What is Metagenomics?

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Biofilm from an acid mine drainage (AMD) site sampled for metagenomic analysis

Metagenomics is a strategy, pioneered by DOE JGI, for isolating, sequencing, and characterizing DNA extracted directly from environmental samples. These data, along with 16s ribosomal RNA signatures, are used to obtain a profile of the microbial community residing in a particular environment. Traditionally, laboratory cultures of microbes were necessary for genome sequencing projects, but most microbes are resistant to cultivation and exist in the environment as part of larger communities, making them harder to isolate and characterize.

 

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