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In Situ BioTransformation of Mercury-Contaminated Groundwater In Kazakhstan Utilizing Native Bacteria (Presentation) |
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The Northern outskirts of Pavlodar were contaminated with mercury as a result of activity at the former PO "Khimprom" chemical plant. The plant produced chlorine and alkali from t...
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Diesel Exhaust Exposure Increases Susceptibility to Influenza Infection and Induces Dendritic Cell Migration and Maturation. |
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Mice were necropsied at day 1, 4, 8 and 14 post-infection and lung tissue was assessed for virus titers by TCID50, lung injury and inflammation. Lung and lymph node DC p...
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EVALUATING HYDROLOGICAL RESPONSE TO FORECASTED LAND-USE CHANGE: SCENARIO TESTING WITH THE AUTOMATED GEOSPATIAL WATERSHED ASSESSMENT TOOL |
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Studies of future management and policy options based on different
assumptions provide a mechanism to examine possible outcomes and especially their likely benefits or consequence...
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HISTORICAL ANALYSIS OF THE RELATIONSHIP OF STREAMFLOW FLASHINESS WITH POPULATION DENSITY, IMPERVIOUSNESS, AND PERCENT URBAN LAND COVER IN THE MID-ATLANTIC REGION |
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Methods: This study is an examination of the relationship between stream flashiness and watershed-scale estimates of percent imperviousness, degree of urban development, and popula...
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HISTORICAL ANALYSIS OF THE RELATIONSHIP OF STREAMFLOW FLASHINESS WITH POPULATION DENSITY, IMPERVIOUSNESS, AND PERCENT URBAN LAND COVER IN THE MID-ATLANTIC REGION |
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Historical US Census population data was used to estimate population
density for 1930-2000 and satellite imagery from circa 1973, 1992, and 2001 was used to estimate the degree of...
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How do we assess wetland condition across broad geographic scales? Lessons learned from the Gulf of Mexico Coastal Wetlands Regional Pilot Assessment . |
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Meeting abstract for invited oral presentation....
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LEVELS OF SYNTHETIC MUSK COMPOUNDS IN MUNICIPAL WASTEWATER FOR ESTIMATING BIOTA EXPOSURE IN RECEIVING WATERS |
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Presentation materials. If further information is requested, please refer to the bibliographic citation and contact the person listed under Principal Investigator...
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PARABENS AND SUNSCREENS IN THE ENVIRONMENT: DETERMINATION BY HPLC-ESI-MS/MS AND GC-MS AND CALCULATION OF PHOTOTOXICITY |
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Ultraviolet (UV)-absorbing chemicals are widely used in cosmetics, sunscreens, and plastics to block UV radiation from the sun. Parabens are preservatives and are used extensively...
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PHARMACEUTICALS AS ENVIRONMENTAL POLLUTANTS: ISSUES REGARDING ANALYSIS |
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The Clean Water Act (CWA) provides the legislative mandate for the United States Environmental Protection Agency’s Water Quality Program to restore and maintain the chemical, physi...
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PROPERTY CHANGES IN AQUEOUS SOLUTIONS DUE TO SURFACTANT TREATMENT OF PCE: IMPLICATIONS TO GEOPHYSICAL MEASUREMENTS |
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Presentation materials. If further information is requested, please refer to the bibliographic citation and contact the person listed under Principal Investigator....
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TREATMENT OF METALS IN GROUND WATER USING AN ORGANIC-BASED SULFATE-REDUCING PERMEABLE REACTIVE BARRIER |
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A pilot permeable reactive barrier (PRB) consisting of a mixture of leaf compost, zero-valent iron (ZVI) filings, limestone and pea gravel was evaluated at a former phosphate ferti...
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(AMD) ANALYSIS OF AIR QUALITY DATA NEAR ROADWAYS USING A DISPERSION MODEL |
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We used a dispersion model to analyze measurements made during a field study conducted by the U.S. EPA in July-August 2006, to estimate the impact of traffic emissions on air quali...
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(CALIFORNIA) META-ANALYSIS OF THE LIFE STYLE FACTORS RELEVANT TO ENVIRONMENTAL HAZARDS FOR THE AGING POPULATION |
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The goal of this U.S. Environmental Protection Agency (EPA) Aging Initiative study is to characterize activity patterns, physiological changes, and environmental exposures for the ...
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*Ambient Particluate Matter Supresses Alveolar Macrophage Cytokine Response to Lipopolysaccharide |
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Reports link ambient particulate matter (PM) exposure with cardiopulmonary mortality and morbidity, including the exacerbation of inflammatory disease and increased hospitalization...
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*Evaluating the toxicity of airborne particulate matter and nanoparticles by measuring oxidative strett potential - A workshop report and consensus statement |
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BACKGROUND: There is a strong need for laboratory in vitro test systems for the toxicity of airborne particulate matter and nanoparticles. The measurement of oxidative stress poten...
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*Iron accumulation in bronchial epithelial cells is dependent on concurrent sodium transport |
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Airway epithelial cells prevent damaging effects of extracellular iron by taking up the metal and sequestering it within intracellular ferritin. Epithelial iron transport is associ...
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2008 Meeting in Germany: Emerging Environmental Contaminants and Current Issues |
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This presentation will discuss emerging environmental contaminants that are currently of concern to the U.S. EPA and to other agencies. Emerging contaminants include drinking water...
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2008 Microarray Research Group (MARG Survey): Sensing the State of Microarray Technology |
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Over the past several years, the field of microarrays has grown and evolved drastically. In its continued efforts to track this evolution and transformation, the ABRF-MARG has once...
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3D Air Quality and the Clean Air Interstate Rule: Lagrangian Sampling of CMAQ Model Results to Aid Regional Pollution Accountability Metrics. |
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Presentation materials. If further information is requested, please refer to the bibliographic citation and contact the person listed under Principlal Investigator...
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IN VITRO METABOLISM OF THYROID HORMONES BY RECOMBINANT HUMAN UDP-GLUCORONOSYLTRANSFERASES AND SULFOTRANSFERASES |
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Endocrine disruptors can decrease thyroid hormone levels via the induction of hepatic uridinediphosphate-glucoronosyltransferases (UGTs) and sulfotransferases (SULTs). Due to their...
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In situ BioTransformation Of Mercury-Contaminated Groundwater In Kazakhstan Utilizing Native Bacteria |
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The Northern outskirts of Pavlodar were contaminated with mercury as a result of activity at the former PO "Khimprom" chemical plant. The plant produced chlorine and alkali from t...
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A Balanced Accuracy Fitness Function Leads to Robust Analysis Using Grammatical Evolution Neural Networks in the Case of Class Imbalance |
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The identification and characterization of genetic and environmental factors that predict common, complex disease is a major goal of human genetics. The ubiquitous nature of epist...
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A CALCIUM-BASED INVASION RISK ASSESSMENT FOR ZEBRA AND QUAGGA MUSSELS (DREISSENA SPP.) |
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We used calcium concentration data from over 3000 stream and river sites across the contiguous United States to classify ecoregions relative to their risk for Dreissena species inv...
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A CASE STUDY ON THE RISKS AND BENEFITS OF DECABDE, A MAJOR BROMINATED FLAME RETARDANT |
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This is a proposal for a roundtable presentation at the 2008 Society of Toxicology Annual Meeting. ABSTRACT BODY: Decabromodiphenyl ether (DecaBDE) is a high production vo...
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A COMPARISON OF INTERCELL METRICS ON DISCRETE GLOBAL GRID SYSTEMS |
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A discrete global grid system (DGGS) is a spatial data model that aids in global research by serving as a framework for environmental modeling, monitoring and sampling across the e...
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A COMPARISON OF STUDIES ON THE EFFECTS OF CONTROLLED EXPOSURE TO FINE, COARSE AND ULTRA FINE AMBIENT PARTICULATE MATTER FROM A SINGLE LOCATION |
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Particle size has been implicated by epidemiological and toxicological
studies as an important determinant of the toxicity of ambient particulate
matter (PM). In an effort to c...
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A Computational Framework for Systems-based Analysis of Developmental Toxicity |
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Discusses the EPA/NCCT ToxRefDB database. The EPA is building capacity for multi-dimensional evaluation of toxicity using information aboout chemical properties, genome-wide respon...
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A DYNAMIC MODEL OF AN ESTUARINE INVASION BY A NON-NATIVE SEAGRASS |
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Mathematical and simulation models provide an excellent tool for examining and predicting biological invasions in time and space; however, traditional models do not incorporate dyn...
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A GREENER SYNTHESIS OF CORE (FE, CU)-SHELL (AU, PT, PD AND AG) NANOCRYSTALS USING AQUEOUS VITAMIN C |
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A greener method to fabricate the novel core (Fe and Cu)-shell (noble metals) metal nanocrystals using aqueous ascorbic acid (vitamin C) is described. Transition metal salts such a...
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A HYBRID MODELING APPROACH TO RESOLVE POLLUTANT CONCENTRATIONS IN AN URBAN AREA |
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A modeling tool that can resolve contributions from individual sources to the urban environment is critical for air-toxics exposure assessments. Air toxics are often chemically rea...
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A MIXTURE OF ORGANOTINS FOUND IN POLYVINYL CHLORIDE (PVC) PIPE IS NOT IMMUNOTOXIC TO SPRAGUE-DAWLEY RATS WHEN GIVEN IN DRINKING WATER |
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Organotin compounds used in PVC pipe production are of concern to the U.S. EPA because they leach from supply pipes into drinking water and are reported multisystem toxicants. We ...
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A MULTIDISCIPLINARY APPROACH TO STORMWATER MANAGEMENT AT THE WATERSHED SCALE. |
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Stormwater runoff from extensive impervious surfaces in urban and suburban areas has led to human safety risks and stream ecosystem impairment, triggering an interest in watershed-...
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A MULTIFACETED, MEDIUM-THROUGHPUT APPROACH FOR DETECTING AND CHARACTERIZING DEVELOPMENTAL NEUROTOXICITY USING ZEBRAFISH. |
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To address the EPA's need to prioritize hundreds to thousands of chemicals for testing, we are developing a rapid, cost-effective in vivo screen for developmental neurotoxicity usi...
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A Macroecological Approach to Forecasting Fisheries Services: How much Energy Does it Take to Catch a Fish? |
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The U.S. Environmental Protection Agency is currently developing methods to quantify freshwater fisheries services (e.g., standing-stock abundance and/or biomass) at multiple spati...
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A Modeling Methodology to Support Evaluation Public Health Impacts on Air Pollution Reduction Programs |
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Environmental public health protection requires a good understanding of types and locations of pollutant emissions of health concern and their relationship to environmental public ...
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A New Electropositive Filter for Concentrating Enterovirus and Norovirus from Large Volumes of Water - MCEARD |
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The detection of enteric viruses in environmental water usually requires the concentration of viruses from large volumes of water. The 1MDS electropositive filter is commonly used...
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A Novel Approach: Chemical Relational Databases, and the Role of the ISSCAN Database on Assessing Chemical Carcinogenity |
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Mutagenicity and carcinogenicity databases are crucial resources for toxicologists and regulators involved in chemicals risk assessment. Until recently, existing public toxicity d...
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A PARTICIPANT-BASED APPROACH TO INDOOR/OUTDOOR AIR MONITORING IN COMMUNITY HEALTH STUDIES |
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Community health studies of traffic-related air pollution have been hampered by the cost and participant burden associated with collecting household-level exposure data. The curre...
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A PBPK MODEL FOR EVALUATING THE IMPACT OF ALDEHYDE DEHYDROGENASE POLYMORPHISMS ON COMPARATIVE RAT AND HUMAN NASAL TISSUE ACETALDEHYDE DOSIMETRY |
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ABSTRACT: Acetaldehyde is an important intermediate in chemical synthesis and a byproduct of normal oxidative metabolism of several industrially important compounds includi...
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A PREDICTIVE MODEL FOR ANTI-DEGRADATION MONITORING OF THE DELAWARE RIVER |
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The non-tidal portion of the Delaware River consists of many large sections designated as Wild and Scenic Rivers and passes through two national parks. Although there is increasing...
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A Pyoverdin Siderophore Produced By Pseudomonas aeruginosa CHL-004 Binds Lead And Other Heavy Metals |
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Heavy metal pollution in soils, sediments and wastewater poses a significant environmental and public health threat due to toxicity and the potential for bioaccumulation in both pl...
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A Pyoverdin Siderophore Produced By Pseudomonas aeruginosa CHL-004 Binds Lead And Other Heavy Metals - (Poster) |
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Heavy metal pollution in soils, sediments and wastewater poses a significant environmental and public health threat due to toxicity and the potential for bioaccumulation in both pl...
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A QUANTITATIVE MODEL FOR XENOBIOTIC METABOLIZING ENZYME (XME) INDUCTION REGULATED BY THE PREGNANE X RECEPTOR (PXR) |
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The nuclear receptor, PXR, is an integral part of the regulation of hepatic metabolism. It has been shown to regulate specific CYPs (phase I drug-metabolizing enzymes) as well as ...
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A RAT MODEL OF HEART FAILURE INDUCED BY ISOPROTERENOL AND A HIGH SALT DIET |
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Rat models of heart failure (HF) show varied pathology and time to disease outcome, dependent on induction method. We found that subchronic (4wk) isoproterenol (ISO) infusion in Sp...
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A REVIEW OF BIOACCUMULATION MODELING APPROACHES FOR PERSISTENT ORGANIC POLLUTANTS |
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Persistent organic pollutants and mercury are likely to bioaccumulate in biological components of the environment, including fish and wildlife. The complex and long-term dynamics i...
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A REVIEW OF THE RODENT CARCINOGENICTY AND MUTAGENICITY OF AMBIENT AIR |
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This is a review of the information known about the carcinogenicity and mutagenicity of urban outdoor air including volatile pollutants and particulate organic material.
The e...
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A Review of the Impact of Climate Variability and Change on Aeroallergens and their Associated Effects (Final Report) |
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This report is a survey of the current state of scientific knowledge of the potential impacts of climate change and climate variability on aeroallergens in the United States -- inc...
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A SIMPLE AND RAPID MATRIX-ASSISTED LASER DESORPTION/IONIZATION TIME OF FLIGHT MASS SPECTRONOMY METHOD TO SCREEN FISH PLASMA SAMPLES FOR ESTROGEN-RESPONSIVE BIOMARKERS |
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In this study, we describe and evaluate the performance of a simple and rapid mass spectral method for screening fish plasma for estrogen-responsive biomarkers using matrix assiste...
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A STUDY OF LAND APPLICATION OF ANAEROBICALLY DIGESTED BIOSOLIDS |
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A field-scale research project was conducted in 2004-2005 to evaluate land application of anaerobically digested biosolids at agronomic levels. Biosolids had not been applied to t...
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A SURROGATE SUBCHRONIC TOXICITY TEST METHOD FOR WATERS WITH HIGH TOTAL DISSOLVED SOLIDS |
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Total dissolved solids (TDS) are often identified as a toxicant in whole-effluent toxicity (WET) testing. The primary test organism used in WET testing, Ceriodaphnia dubia, is very...
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A Screening Assessment of the Potential Impacts of Climate Change on Combined Sewer Overflow (CSO) Mitigation in the Great Lakes and New England Regions (Final Report) |
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This report is a screening-level assessment of the potential implications climate change has had on combined sewer overflow (CSO) mitigation in the Great Lakes and New England Regi...
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A Simple Paper Describing the Analysis of Lake Water for Perchlorate and Responses to the Paper in Newspapers and Internet Websites. |
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Analysis of Lake Water for Perchlorate and Responses....
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A Spreadsheet-based GIS tool for planning aerial photography |
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The U.S.EPA's Pacific Coastal Ecology Branch has developed a tool which facilitates planning aerial photography missions. This tool is an Excel spreadsheet which accepts various i...
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A Streamlined Monitoring Framework for Low Impact Development Stormwater Management Practices - Albuquerque |
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In many respects, the collection, of monitoring data has become standard "boilerplate" in grant proposals that fund non point source management projects. This approach typically ca...
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A Streamlined Monitoring Framework for Sustainable and Low Impact Development Stormwater Management Practices - 2 |
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The problems of urbanization and stormwater management, as they pertain to monitoring the condition of water and environmental resources, are grounded in issues of scale, connectiv...
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A TOXICOLOGICAL VIEW OF ISSUES AND APPROACHES |
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Mode of action (MOA) is a powerful approach which can be used to improve extrapolations and understanding of relevance from studies of animals to humans, to inform differential sus...
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A Transcriptional Regulatory Switch Underlying B-Cell Terminal Differentiation and Its Disruption by Dioxin (S) |
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The terminal differentiation of B cells in lymphoid organs into antibody-secreting plasma cells upon antigen stimulation is a crucial step in the humoral immune response. The archi...
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A Transcriptional Regulatory Switch Underlying B-Cell Terminal Differentiation and its Disruption by Dioxin |
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The terminal differentiation of B lymphocytes into antibody-secreting plasma cells upon antigen stimulation is a crucial step in the humoral immune response. The mutually-repressi...
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A View From Within |
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The U.S. Environmental Protection Agency (U.S. EPA) was established in 1970. The U.S. EPA is an agency of statutes and is driven by 29 different environmental laws passed by Congr...
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A YOUNG SCIENTIST'S GUIDE TO GAINFUL EMPLOYMENT: RECENT GRADUATES' EXPERIENCES AND SUCCESSFUL STRATEGIES |
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Securing a job after completing a graduate degree is among a graduate student's most rewarding (and most stressful) experiences. The job hunting process, from submitting an applica...
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A case study of Membrane Testing, Integrity and Estimations of Log Removal Value per the Long Term 2 Enhanced Surface Water Treatment Rule. |
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The SWTR-LT2 Rule addresses the use of membranes that may be used to achieve credits for the reduction of Cryptosporidium. The LT2 Rule requires product-specific testing of membra...
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A core set of microsatellite markers for Western Corn Rootworm (Coleoptera: Chrysomelidae) population genetics studies |
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Interest in the ecological and population genetics of the western corn rootworm, Diabrotica virgifera virgifera LeConte, has grown rapidly in the last few years in North America an...
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A mixture of five phthalate diesters cummulatively inhibit fetal testicular testoserone production in a manner consisent with their predicted reporduction toxicity in the Sprague Dawley rat. |
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Phthalate diesters are commonly-used plasticizers in intravenous bags, plastic food wrap and children’s toys, and the metabolites of multiple phthalates are detected in humans. In...
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A multidisciplinary approach to sub-national sustainability |
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The USEPA is investigating sustainability metrics from an economic and environmental perspective to determine their applicability at a sub-national level. Metrics are derived from ...
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A predictive model for anti-degradation monitoring of the Delaware River mainstem |
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The non-tidal portion of the Delaware River can be considered to be in minimally disturbed condition, but there is increasing pressure on the watershed. Thus, the primary goal of ...
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A review on setting appropriate reach length for biological assessment of boatable rivers |
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Researchers working on boatable rivers are presented with the task of selecting an appropriate stream length, or reach length, from which data will be collected. Ideally, the sampl...
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A roughness-corrected index of relative bed stability for regional stream surveys |
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Quantitative regional assessments of streambed sedimentation and its likely causes are hampered because field investigations typically lack the requisite sample size, measurements,...
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ABRF-MARG RESEARCH STUDY: EVALUATION OF SMALL SAMPLE NUCLEIC ACID AMPLIFICATION TECHNOLOGIES FOR GENE EXPRESSION PROFILING |
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Microarrays have had a significant impact on many areas of biology. However, there are still many fertile research areas that would benefit from microarray analysis but are limited...
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ACID FUNCTIONALIZED SINGLE-WALLED CARBON NANOTUBES ENHANCE CARDIAC ISCHEMIC/REPERFUSIOIN INJURY |
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Engineered carbon nanotubes are being intensively developed for wide applications. Because of their unique light properties, nanotubes can impose some potentially toxic effects, p...
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ACUTE BEHAVIORAL EFFECTS OF INHALED PERCHLOROETHYLENE IN RATS ARE DIRECTLY RELATED TO ITS CONCENTRATION IN THE BRAIN. |
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Perchloroethylene (PCE) is a volatile organic compound (VOC), frequently used in dry cleaning processes, that is currently being assessed by EPA for its risk to human health. Many ...
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ACUTE EXPOSURE TO PARTICULATE MATTER IN A RAT MODEL OF HEART FAILURE |
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Human exposure to ambient particulate matter (PM) has been linked to cardiovascular morbidity and mortality. This association strengthens in people with preexisting cardiopulmonary...
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ACUTE POSTNATAL EXPOSURE TO BROMINATED DIPHENYLETHER 47 DELAYS NEUROMOTOR ONTOGENY AND ALTERS MOTOR ACTIVITY IN MICE |
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Polybrominated diphenyl ethers (PBDEs) are widely used commercial flame retardants that are accumulating in the environment. 2,2’,4,4’-Brominated diphenyl ether (BDE 47) is a very...
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ACUTE RESPIRATORY HEALTH EFFECTS OF AIR POLLUTION ON ASTHMATIC CHILDREN IN US INNER CITIES |
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BACKGROUND: Children with asthma in inner-city communities may be particularly vulnerable to adverse effects of air pollution because of their airways disease and exposure to relat...
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ADDING ECOLOGICAL REALISM TO PLANT TESTING |
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Current test protocols for the protection of nontarget plants used when registering pesticides in the United States and many other countries depend on two tests using greenhouse gr...
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ADULT COHO SALMON AND STEELHEAD USE OF BOULDER WEIRS IN SOUTHWEST OREGON STREAMS |
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The placement of log and boulder structures in streams is a common and often effective technique for improving juvenile salmonid rearing habitat and increasing fish densities. Less...
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ADVANCED OXIDATION PROCESSES IN THE TREATMENT OF CONTAMINANT CANDIDATE LIST (CCL) COMPOUNDS |
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The current (2nd) Contaminant Candidate List was completed in 2005 by the United States EPA as an update to the Safe Drinking Water Act. The list of 42 chemical contaminants spans ...
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AIR POLLUTION, OXIDATIVE STRESS AND NEUROTOXICITY. |
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Increased incidents of classic and variant forms of neurodegenerative diseases suggest that environmental chemicals and susceptibility factors (e.g., genetics, diseased states, obe...
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AJE invited commentary: Measuring social disparities in health - what was the question again? |
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Monitoring social disparities in health is not a straightforward project. Defining what constitutes a disparity is challenging, and multiple measures have been proposed to track ch...
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ALLERGIC ASTHMA AND THE DEVELOPING IMMUNE SYSTEM: A PILOT STUDY |
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Rationale: The predisposition towards atopic disease begins early in life, and that the risk of developing asthma is heightened following prenatal exposure to some compounds. None...
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AN ANIMAL MODEL OF PLATINUM (PT) HYPERSENSITIVITY |
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Exposure to Pt salts has been associated with occupational asthma. Pt, the most active component and widely used metal in catalytic converters, is released in automobile exhaust an...
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AN APPROACH FOR EVALUATING THE EFFECTIVENESS OF VARIOUS OZONE AIR QUALITY STANDARDS FOR PROTECTING TREES |
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We demonstrate an approach for evaluating the level of protection attained using a variety of forms and levels of past, current, and proposed Air Quality Standards (AQSs). The U.S....
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AN APPROACH TO DEVELOPING NUTRIENT CRITERIA FOR PACIFIC NORTHWEST ESTUARIES: A CASE STUDY OF YAQUINA ESTUARY, OREGON |
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NHEERL scientists have developed an approach that could be used by the State of Oregon for development of nutrient and other water quality criteria for the Yaquina Estuary, Oregon....
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AN ASSESSMENT OF THE FATE OF METAL OXIDE NANOMATERIALS IN POROUS MEDIA |
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Developing procedures for assessing the potential environmental fate and transport of nanomaterials is an active endeavor of the environmental technical research community. Insuffi...
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AN EVALUATION OF THE PROTEIN MASS OF PARTICULATE MATTER |
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A comparison of ambient particulate matter mass concentrations with the total protein mass concentration has not been performed previously for North Carolina and was the goal of th...
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AN EXAMPLE OF MODEL STRUCTURE DIFFERENCES USING SENSITIVITY ANALYSES IN PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELS OF TRICHLOROETHYLENE IN HUMANS |
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Abstract
Trichloroethylene (TCE) is an industrial chemical and an environmental contaminant. TCE and its metabolites may be carcinogenic and affect human health. Physiologically ...
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AN INDEX OF COMPOSITIONAL DISSIMILARITY BETWEEN OBSERVED AND EXPECTED ASSEMBLAGES |
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The reference-condition approach to bioassessment often uses the observed/expected (O/E) ratio to indicate anthropogenic alteration of aquatic macroinvertebrates, fish, or periphyt...
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AN OPEN-SOURCE COMMUNITY WEB SITE TO SUPPORT GROUND-WATER MODEL TESTING |
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A community wiki wiki web site has been created as a resource to support ground-water model development and testing. The Groundwater Gourmet wiki is a repository for user supplied...
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ANALYSIS OF FUNGAL SPORE MYCOTOXIN AND THE RELATIONSHIP BETWEEN SPORE SURFACE AREA AND MYCOTOXIN CONTENT UTILIZING A PROTEIN TRANSLATION INHIBITION ASSAY |
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Due to mounting evidence suggesting that biological contamination in the built environment may cause a myriad of adverse health effects, research aimed at understanding the potenti...
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ANALYSIS OF PERFLUORINATED CARBOXYLIC ACIDS IN SOILS II: OPTIMIZATION OF CHROMATOGRAPHY AND EXTRACTION |
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With the objective of detecting and quantitating low concentrations of perfluorinated carboxylic acids (PFCAs), including perfluorinated octanoic acid (PFOA), in soils, we compared...
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ANALYSIS OF THE ENANTIOMERS OF CHIRAL PESTICIDES AND OTHER POLLUTANTS IN ENVIRONMENTAL SAMPLES BY CAPILLARY ELECTROPHORESIS |
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The generic method described here involves typical capillary electrophoresis (CE) techniques, with the addition of cyclodextrin chiral selectors to the electrolyte for enantiomer ...
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ANALYSIS OF TOLUENE AT DIFFERENT LIFE STAGES IN BROWN NORWAY RATS. |
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Differential susceptibility to environmental exposures in subsets of the population is a major regulatory concern of the Environmental Protection Agency. Of special interest is th...
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ANALYTICAL PROTOCOL (GC/ECNIMS) FOR OSWER'S RESPONSE TO OIG REPORT (2005-P-00022) ON TOXAPHENE ANALYSIS |
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The research approached the large number and complexity of the analytes as four separate groups: technical toxaphene, toxaphene congeners (eight in number), chlordane, and organoch...
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APOPTOSIS GENE EXPRESSION IN HUMAN EPDERMAL KERATINOCYTES TREATED WITH SODIUM ARSENITE USING REAL TIME PCR ARRAY |
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Arsenic exposure via contaminated drinking water is a great public health concern worldwide. Chronic arsenic exposure has been associated with human skin, lung and bladder cancer a...
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APPLICATION OF A WATERSHED NITROGEN LOADING MODEL FORTY-NINE (49) MEDIUM SIZED SOUTHERN NEW ENGLAND EMBAYMENT TYPE ESTUARIES |
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Platform presentation at a scientific conference...
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APPLICATION OF THE TISSUE RESIDUE APPROACH TO EVALUATE TOXICITY OF ORGANIC CONTAMINANTS. |
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Abstract for presentation....
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ARSENIC SPECIATION ANALYSIS IN HUMAN SALIVA |
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Background: Determination of arsenic species in human saliva is potentially useful for biomonitoring of human exposure to arsenic and for studying arsenic metabolism. However, ther...
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ASSESSING HABITAT QUALITY OF MOUNT HOPE BAY AND NARRAGANSETT BAY USING GROWTH, RNA:DNA, AND FEDDING HABITS OF CAGED JUVENILE WINTER FLOUNDER |
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Somatic growth rates, RNA:DNA, and feeding habits of juvenile Pseudopleuronectes americanus (Winter Flounder) were used to asses small-scale spatio-temporal variations in the habit...
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ASSESSING THE HEALTH EFFECTS AND RISKS ASSOCIATED WITH CHILDREN’S INHALATION EXPOSURES – ASTHMA AND ALLERGY |
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Adults and children may have different reactions to inhalation exposures, which may be the result of differences in inhaled or target tissue doses following similar exposures, and/...
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ASSESSING VULNERABILITIES FROM ALTERNATIVE DEVELOPMENT PATTERNS |
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Planners in a rapidly urbanizing area must take into account trade offs between
multiple environmental issues of concern. A 15-county region centered on Charlotte, North
Carolina...
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ASSESSMENT OF THE WINTER-TIME PERFORMANCE OF DEVELOPMENTAL PARTICULATE MATTER FORECASTS WITH THE ETA-CMAQ MODELING SYSTEM |
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It is desirable for local air quality agencies to accurately forecast tropospheric PM2.5 concentrations to alert the sensitive population of the onset, severity and dura...
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ASTHMATIC HUMAN SERUM IGE-REACTIVITY WITH MOLD EXTRACTS |
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Although molds have demonstrated the ability to induce allergic asthma-like responses in mouse models, their role in human disease is unclear. This study was undertaken to provide ...
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AUTOMATED GEOSPATIAL WATERSHED ASSESSMENT (AGWA) DOCUMENTATION VERSION 2.0 |
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The Automated Geospatial Watershed Assessment Http://www.epa.gov/nerlesd1/landsci/agwa/introduction.htm and www.tucson.ars.ag.gov/agwa) tool is a GIS interface jointly
developed b...
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AUTOMATED GEOSPATIAL WATERSHED ASSESSMENT (AGWA): A GIS-BASED HYRDOLOGIC MODELING TOOL FOR WATERSHED ASSESSMENT AND ANALYSIS |
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The Automated Geospatial Watershed Assessment tool (AGWA) is a GIS interface jointly
developed by the USDA Agricultural Research Service, the U.S. Environmental Protection |
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Abiotic Removal of TCE and cis-DCE by Magnetite Under Aerobic Conditions in Ground Water |
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Abiotic Removal of TCE and cis-DCE by Magnetite Under Aerobic Conditions in Ground Water...
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Acute effects of ethanol or d-amphetamine on the locomotor activity of larval zebrafish in a microtiter plate format. |
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As part of an effort to develop a rapid in vivo screen for EPA’s prioritization of toxic chemicals, we have begun to characterize the locomotor activity of zebrafish (Danio rerio) ...
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Acute inhalation of 2,2,4-trimethylpentane alters visual evoked potentials and signal detection behaviour of rats. |
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The volatile organic compound 2,2,4-trimethylpentane (TMP, “isooctane”) is a primary constituent of gasoline for which the current health effects data are insufficient to permit EP...
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Acute pulmonary function response to ozone in young adults as a function of body mass index |
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Recent studies have shown enhanced responsiveness to ozone in obese mice. Adiposity has not been examined as a possible modulator of ozone response in humans. We therefore examined...
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Advances in Toxico-Cheminformatics: Supporting a New Paradigm for Predictive Toxicology |
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EPA’s National Center for Computational Toxicology is building capabilities to support a new paradigm for toxicity screening and prediction through the harnessing of legacy toxicit...
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Advantages and Challenges of Electronic Records for Scientific Data at the US EPA |
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Paper, hard-bound notebooks have been the traditional method of collecting data for research studies at the US EPA, RTP, NC. Indeed, ORD recently issued an operating procedure for...
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Aggregation and Deposition of C60 in Aqueous Systems |
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The extremely low water solubility of many fullerenes precludes aqueous solution processing for engineering applications and minimizes the potential for fullerene environmental eff...
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Air Pollution Monitoring Site Selection by Multiple Criteria Decision Analysis |
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Criteria air pollutants (particulate matter, sulfur dioxide, oxides of nitrogen, volatile organic compounds, and carbon monoxide) as well as toxic air pollutants are a global conce...
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Air pollution and respiratory viral infection |
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Despite current regulations, which limit the levels of certain air pollutants, there are still a number of adverse health effects that result from exposure to these agents. Numerou...
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Altered Axial Skeletal Development |
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The axial skeleton is routinely examined in standard developmental toxicity bioassays and has proven to be sensitive to a wide variety of chemical agents. Dysmorphogenesis in the s...
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Alternative Asbestos Control Method (AACM) Research |
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This presentation describes the status to date of the Alternative Asbestos Control Method research, which is intended as a possible alternative technology for use in the demolition...
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Alternative Asbestos Control Method (AACM) Research - Baltimore, MD |
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This presentation describes the status to date of the Alternative Asbestos Control Method research, which is intended as a possible alternative technology for use in the demolition...
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Alternative Asbestos Control Method (AACM) Research - Feb 2008 |
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This presentation describes the status to date of the Alternative Asbestos Control Method research, which is intended as a possible alternative technology for use in the demolition...
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Alternative Asbestos Control Method (AACM) Research, 5/06/2008 |
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This presentation describes the status to date of the Alternative Asbestos Control Method research, which is intended as a possible alternative technology for use in the demolition...
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Alternative Asbestos Control Method (AACM) at GEBO |
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This presentation describes the status to date of the AACM research, which is intended as a possible alternative technology for use in the demolition of buildings that contain asbe...
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Alternative Asbestos Control Method (AACM), Washington |
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This presentation describes the status to date of the Alternative Asbestos Control Method research, which is intended as a possible alternative technology for use in the demolition...
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Ambient air pollution particles and the acute exacerbation of chronic obstructive pulmonary disease |
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Investigation has repeatedly demonstrated an association between exposure to ambient air pollution particles and numerous indices of human morbidity and mortality. Individuals with...
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An Environmental Technology Verification (ETV) Testing of a Ballast Exchange Assurance Meter (BEAM) 100 |
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Mid-ocean ballast water exchange (BWE) is mandatory for all vessels entering U.S. waters from outside the 200-mile exclusive economic zone. To support such regulation, accurate an...
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An Introduction to ToxCast™ |
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ToxCast™ is a chemical prioritization research program to develop the ability to forecast toxicity using bioactivity profiling. The point is to use results in a variety of in vitr...
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An Update on ToxCast™ |
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In its first phase, ToxCast™ is profiling over 300 well-characterized chemicals (primarily pesticides) in over 400 HTS endpoints. These endpoints include biochemical assays of prot...
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An Update on U.S. Gasoline Composition |
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There is no abstract for this product. If further information is requested, please refer to the bibliographic citation and contact the person listed under Contact field....
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An Update on the EPA Study of Lead Scavengers (EDB and DCA) |
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In response to continued concerns about the concentrations of 1,2-dibromoethane (EDB) in ground water from spills of leaded gasoline, OUST formed a Lead Scavengers Team with assist...
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An Update on the Progress of the Extended One-Generation Reproductive Protocol |
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Consistent with a more science-based approach assessing potential adverse effects of pesticides, the ILSI-HESI Agricultural Chemical Safety Assessment (ACSA) Technical Committee, p...
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An integrated assessment of dredging remediation of a midwestern stream using sediment chemistry, water quality, bioassessment and fish biomarkers |
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Abstract for presentation at SETAC North America 29th annual meeting, November 16-20, 2008, in Tampa, FL....
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Analyses of the Effects of Global Change on Human Health and Welfare and Human Systems (SAP 4.6) |
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EPA is announcing the final report entitled, Synthesis and Assessment Product 4.6: Analyses of the Effects of Global Change on Human Health and Welfare and Human Systems ....
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Analysis of 16S rDNA and Metagenomic Sequences Revealed Microbial Community and Host-Specific Sequences of Canadian Geese Feces |
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There is an increasing concern regarding the public health risks associated with waterfowl fecal pollution as a result of the increase in geese populations (Branta canadensis) in o...
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Analysis of Arsenical and Their Sulfur Analogs Using HPLC with Collision Cell ICP-MS and ESI-MS |
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Slide presentation at the 2nd International Congress: Arsenic in the Environment, Valencia, Spain, May 21-23, 2008...
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Analysis of Arsenicals and Their Sulfur Analogs in Biological Samples Using HPLC with Collision Cell ICP-MS and ESI-MS/MS |
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Recent arsenic speciation studies have indicated that the sulfur analogs of the more common arsenic oxides are present in environmental and biological systems. This discovery was p...
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Analysis of Enterococci and Bacteriodales Fecal Indicator Bacteria in a Lake Michigan Tributary by Real-Time Quantitative PCR |
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The Salt Creek watershed in northwest Indiana drains into Lake Michigan near several heavily used recreational beaches. This study aimed to investigate the levels of fecal indicat...
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Analysis of Fish and Shellfish Community Patterns in the Mobile Bay Estuary, USA |
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To present information on the analysis of fish and shellfish community patterns in the Mobile Bay....
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Analysis of ecologically relevant pharmaceuticals in wastewater and surface water using selective solid phase extraction and UPLC/MS/MS |
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A rapid and sensitive method has been developed for the analysis of 48 human prescription active pharmaceutical ingredients (APIs) and 6 metabolites of interest, utilizing selectiv...
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Analysis of the Sensitivity and Uncertainty in 2-Stage Clonal Growth Models for Formaldehyde with Relevance to Other Biologically-Based Dose Response (BBDR) Models |
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The National Center for Environmental Assessment (NCEA) has conducted and supported research addressing uncertainties in 2-stage clonal growth models for cancer as applied to forma...
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Anthropogenic Eutrophication of Narragansett Bay: Evidence from Dated Sediment Cores |
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The organic matter preserved in estuarine sediments provides a number of useful indicators, or "proxies" that can be used to infer paleoenvironmental changes One type of paleoenvir...
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Anthropogenic sedimentation in Pacific Northwest streams inferred from Aquatic Habitat Survey datausing a relative bed stability index |
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We evaluated anthropogenic sedimentation in U.S. Pacific Northwest coastal streams using an index of relative bed stability (LRBS*) based on low flow survey data collected using th...
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Apples: A Standard Food for Determining Potential Residential Pesticide Transfers |
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Children’s unstructured eating behaviors lend themselves to potential
dietary exposures to synthetic pyrethroid pesticides applied in the
home. To determine the potential for exc...
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Application Of Synchrotron Techniques To Investigate In-Situ Arsenic Speciation |
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The speciation, or chemical form of elements governs their fate, toxicity, mobility, and bioavailability in contaminated soils, sediments and water as well as food chain transfer m...
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Application of Stable Carbon Isotope Ratios to Recognize Natural Biodegradation of MTBE |
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The organisms that degrade MTBE under anaerobic conditions are evolved to acquire energy for growth by using molecular hydrogen and carbonate ion to cleave methyl ether bonds. Met...
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Application of Synchrotron Techniques in Environmental Science |
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The complexity of metal contaminated sites has and continues to be simplified to a measure of the total metal content. While total metal content is a critical measure in assessing ...
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Application of Toxicological and Health Risk Assessment Approaches to Investigate Chemical Constituents in Drinking Water |
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Chemical disinfection of water has been practiced since the beginning of the 20th century and has resulted in significant gains in public health protection due to decreased exposur...
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Application of restoration scenarios to basin-scale demographics of coho salmon inferred from pit-tags |
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Effective habitat restoration planning requires correctly anticipating demographic responses to altered habitats. New applications of Passive Integrated Transponder (PIT) tag tech...
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Application of satellite aerosol optical depth and airborne LIDAR data for monitoring fine particulate concentration in San Joaquin Valley, California |
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Presentation materials. If further information is requested, please refer to the bibliographic citation and contact the person listed under Principal Investigator....
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Application of the In Silico Toxicant-Target Approach to Screening a Chemical Library for Estrogenicity |
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In this study the capacity of a series of 318 chemicals to bind to the estrogen receptor has been evaluated using three different methods for docking. ...
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Applications Of Nanomaterials In Risk Management Of Environmental Pollutants: The Use Of Bimetallic Systems |
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Remediation of sediments and water contaminated hydrophobic organic chemicals (HOCs) such as polychlorinated biphenyls (PCBs) remains a scientific and technical challenge. PCBs-co...
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Approaches to Estimating the Waterborne Disease Outbreak Burden in the U.S.: Uses and Limitations of the Waterborne Disease Outbreak Surveillance System (Final Report) |
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This report demonstrates how data from the Waterborne Disease Outbreak Surveillance System (WBDOSS) can be used to estimate disease burden and presents results using 30 years of da...
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Aquatic risks posed by pharmaceutical use |
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Oral presentation at the Toxicology and Risk Assessment Conference 2008....
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Arabidopsis transcriptional responses differentiating closely related chemicals (herbicides) and cross-species extrapolation to Brassica |
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Using whole genome Affymetrix ATH1 GeneChips we characterized the transcriptional response of Arabidopsis thaliana Columbia 24 hours after treatment with five different herbicides....
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Are bryophytes useful indicators of hydrologic permanence in forested headwater streams? |
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Court cases have recently questioned whether all headwater streams, particularly non-perennial streams, should be protected in the U.S. under the Clean Water Act. Rapid field-based...
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Are environmental exposures to chlorophenoxy herbicides associated with adverse human health effects? |
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Background: Exposures to environmental pollutants are suspected of playing a role in the observed increases of many diseases. However, it is difficult to establish a firm link be...
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Are there prospects for enhanced groundwater recharge via infiltration of urban stormwater runoff? |
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This presentation will cover the basics of what a storm water best management practices and focus on infiltration-type practices using the example of rain gardens. I will demonstra...
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Arsenic (+3 oxidation state) methyltransferase and the methylation of arsenicals in the invertebrate chordate Ciona intestinalis |
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The biotransformation of inorganic arsenic (iAs) involves methylation by an arsenic (+3 oxidation state) methyltransferase (AS3MT), yielding methyl arsenic (MA), dimethyl arsenic ...
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Arsenic Fate, Transport And Stability Study: Groundwater, Surface Water, Soil And Sediment Investigation At Fort Devens Superfund Site |
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A field investigation was conducted to examine the distribution of arsenic in groundwater, surface water, and sediments at the Fort Devens Superfund Site. The study area encompass...
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Arsenic and Ammonia-Related Drinking Water Research in Region V |
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TTEB is conducting a number of arsenic and ammonia related research with communities in Region V. The objective of this presentation is to provide an overview of some of the key f...
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Assessing Exposure to Waterborne Pathogens |
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In the U.S, and other developed countries, application of the multi-barrier approach for protecting and treating water supplies has led to the virtual elimination of waterborne thr...
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Assessing patterns of fish demographics and habitat in stream networks |
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Effective habitat restoration planning requires correctly anticipating demographic responses to altered habitats. New applications of Passive Integrated Transponder (PIT) tag tech...
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Assessing the Global Potential and Regional Implications of Promoting Bioenergy |
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There is no simple answer to the question “are materials from bio-based feedstocks environmentally, and socially, preferable?” Bioenergy as an alternative energy source might be ef...
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Assessing the effectiveness of low-pressure ultraviolet light for inactivating Mycobacterium avium complex (MAC) micro-organisms |
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Aims: To assess low-pressure ultraviolet light (LP-UV) inactivation kinetics of Mycobacterium avium complex (MAC) strains in a water matrix using collimated beam apparatus.
Meth...
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Assessing the global potential and regional implications of promoting bio-energy |
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There is no simple answer to the question “are materials from bio-based feedstocks environmentally, and socially, preferable?” Bioenergy as an alternative energy source might be ef...
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Assessment of Caudal Fin Clips as a Non-lethal Technique for Predicting Muscle Tissue Mercury Concentrations in Largeouth Bass |
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The statistical relationship between total mercury (Hg) concentration in clips from the caudal fin and muscle tissue of largemouth bass (Micropterus salmoides) from 26 freshwater s...
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Assessment of a Point-of-Use Ultrafiltration System for Turbidity and Microbial Pathogen Removal |
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U.S. EPA’s Office of Research and Development has been evaluating the performance of point-of-use (POU) devices designed for use in homes and small businesses for many years. In co...
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Assessment of the Impacts of Global Change on Regional U.S. Air Quality (External Review Draft) |
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This report was prepared by the Global Change Research Program in the National Center for Environmental Assessment (NCEA) of the Office of Research and Development (ORD) at the ...
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Atmospheric Deposition of Mercury |
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With the advent of the industrial era, the amount of mercury entering the global environment increased dramatically. Releases of mercury in its elemental form from gold mines and c...
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Atmospherically deposited PBDEs, pesticides, PCBs, and PAHs in Western US National Park fish: Concentrations and consumption guidelines |
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Concentrations of polybrominated diphenyl ethers (PBDEs), pesticides, polychlorinated biphenyls (PCBs), and polycyclic aromatic hydrocarbons were measured in 136 fish from 14 remot...
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BACTERIAL MORTALITY DUE TO SOLAR RADIATION, COMPARING EXPERIMENTAL AND STATISTICAL EVIDENCE |
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Many researchers report that sunlight is a primary stressor of beach indicator bacteria. Some water quality models include code that quantifies the effect of radiation on bacterial...
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BENCHMARK DOSES FOR CHEMICAL MIXTURES: EVALUATION OF A MIXTURE OF 18 PHAHS. |
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Benchmark doses (BMDs), defined as doses of a substance that are expected to result in a pre-specified level of "benchmark" response (BMR), have been used for quantifying the risk ...
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BENTHIC COMMUNITY RESPONSE TO SEDIMENT AMENDMENTS |
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The amendments apatite, organoclay, acetate, chitin, and geotextile reactive mats containing apatite and apatite + organoclay are currently under examination for remediation of con...
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BENZO[A]PYRENE-7,8-QUINONE FORMS COVALENT-DNA ADDUCTS IN VITRO BUT NONE WERE DETECTED IN THE LUNGS OR LIVERS OF STRAIN A/J MICE IN VIVO |
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Benzo[a]pyrene (B[a]P) is a potent human and rodent lung carcinogen. This activity has been ascribed in part to the formation of B[a]P-7,8-dio1-9,10-epoxide (BPDE)-DNA adducts. Oth...
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BIAS IN POPULATION GROWTH RATE ESTIMATION: SPARSE DATA, PARTIAL LIFE CYCLE ANALYSIS AND JENSEN'S INEQUITY |
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Demographic matrix models have become an integral part of population viability analysis for threatened and endangered species, but their use is often limited by data availability. ...
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BIOAVAILABILITY OF CHEMICAL CONTAMINANTS IN AQUATIC SYSTEMS |
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Before a chemical can elicit toxicity, the animal must accumulate a dose at a target tissue of sufficient magnitude to produce a response. Bioavailability refers to the degree to w...
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BIOMARKERS |
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Chapter 16 in book, "Toxicology of Fishes", DiGiulio and Hinton eds....
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BRAIN CHOLINESTERASE INHIBITION AND DEPRESSION OF THE PHOTIC AFTER DISCHARGE (PHAD) OF FLASH EVOKED POTENTIALS (FEPS) IN LONG EVANS RATS FOLLOWING ACUTE OR REPEATED EXPOSURES TO A MIXTURE OF CARBARYL AND PROPOXUR. |
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Carbaryl and propoxur are N-methyl carbamate pesticides (NMCs) which are part of the EPA’s cumulative risk assessments for NMCs. These NMCs inhibit cholinesterase (ChE) activity an...
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BUILDING MODEL ANALYSIS APPLICATIONS WITH THE JOINT UNIVERSAL PARAMETER IDENTIFICATION AND EVALUATION OF RELIABILITY (JUPITER) API |
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The open-source, public domain JUPITER (Joint Universal Parameter IdenTification and Evaluation of Reliability) API (Application Programming Interface) provides conventions and For...
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Bay Scallop Habitat Suitability Models: Predictions over Space and Time |
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A survey of Lagoon Pond, Martha’s Vineyard, MA, USA was conducted in September 2005 to determine the combination of habitat factors most highly correlated with bay scallop (Argopec...
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Bayesian Modeling of the Assimilative Capacity Component of Stream Nutrient Export |
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Implementing stream restoration techniques and best management practices to reduce nonpoint source nutrients implies enhancement of the assimilative capacity for the stream system....
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Behavorial effects of exposure to carbon monoxide (CO) |
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I. 43 reported human studies
II. Summary of findings
A. 21 found significant effects, 22 did not
B. Mean COHb was higher for non-
significant studies...
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Benthic Macroinvertebrate Assemblages and Environmental Correlates in Springs of the Ridge and Valley Province |
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Springs are unique features in the landscape that provide important habitat for benthic invertebrates, yet there are few studies characterizing the distribution of benthic macro in...
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Benthic diatom composition in wet and dry isolated forested wetlands: implications for monitoring and assessment (presentation) |
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Oral presentation - no abstract...
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Binding of Vapour-Phase Mercury (Hg0) on Chemically Treated Bauxite Residues (Red Mud) |
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In this study, Hg capture using red mud, seawater-neutralized red mud, and acid-treated red mud is evaluated and compared to other, more conventional sorbent materials. Red mud (al...
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Biodegradation – Monitored Natural Attenuation (MNA) for Oxygenates: How it Evolved, why it Occurs and Using Stable Carbon Isotopes to Predict Plume Behavior |
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The organisms that degrade MtBE under anaerobic conditions are evolved to acquire energy for growth by using molecular hydrogen and carbonate ion to cleave methyl ether bonds. Met...
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Brazilian Free-tailed Bats (Tadarida brasiliensis) as Insect Pest Regulators in Transgenic and Conventional Cotton Crops |
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During the past 12,000 years agricultural systems have transitioned from natural habitats to conventional agricultural regions, and recently to large areas of genetically- engineer...
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Briefing on geological sequestration |
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Geological sequestration (GS) is generally recognized as the injection and long-term (e.g., hundreds to thousands of years) trapping of gaseous, liquid or supercritical carbon diox...
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Briefing on geological sequestration (Tulsa) |
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Geological sequestration (GS) is generally recognized as the injection and long-term (e.g., hundreds to thousands of years) trapping of gaseous, liquid or supercritical carbon diox...
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Bromine Incorporation in Regulated and Emerging DBPs and the Relative Predominance of Mono-, Di-, and Trihalogenated DBPs |
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Brominated disinfection by-products (DBPs) (in general) appear to be more cytotoxic and genotoxic than the chlorinated species, and some of the dihalogenated species are more toxic...
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Bt crop effects on functional guilds of non-target arthropods: A meta-analysis (journal) |
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Background: Uncertainty persists over the environmental effects of genetically-engineered crops that produce the insecticidal Cry proteins of Bacillus thuringiensis (Bt). We perfor...
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CALCULATING PHYSICAL PROPERTIES OF ORGANIC COMPOUNDS FOR ENVIRONMENTAL MODELING FROM MOLECULAR STRUCTURE |
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Mathematical models for predicting the transport and fate of pollutants in the environment require reactivity parameter values-- that is value of the physical and chemical constant...
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CALIBRATION OF SUBSURFACE BATCH AND REACTIVE-TRANSPORT MODELS INVOLVING COMPLEX BIOGEOCHEMICAL PROCESSES |
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In this study, the calibration of subsurface batch and reactive-transport models involving complex biogeochemical processes was systematically evaluated. Two hypothetical nitrate b...
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CAN FAST REPETITION RATE FLUOROMETRY AND SATELLITE OCEAN COLOR DATA BE COMBINED TO EXAMINE GULF OF MEXICO HYPOXIA? |
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Abstract for presentation...
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CAPE-OPEN Thermodynamic Interfaces: Description and Usage |
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CO-LaN will offer a training course focused on the CAPE-OPEN Thermodynamic interfaces and especially version 1.1 of these interfaces....
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CARCINOGENICITY OF HOUSEHOLD SOLID FUEL COMBUSTION AND OF HIGH-TEMPERATURE FRYING |
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In October, 2006, 19 scientists from eight countries met at the International Agency for Research on Cancer (IARC) in Lyon, France, to assess the carcinogenicity of household solid...
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CARDIOVASCULAR AND OTHER HEALTH EFFECTS ASSOCIATED WITH ARSENIC EXPOSURE IN INNER MONGOLIA |
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Arsenic exposure is associated with cardiovascular and other health effects. The study objectives were to investigate the mode of action and to assess dose-response relationships o...
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CATALYTIC OXIDATION OF DIMETHYL SULFIDE WITH OZONE: EFFECTS OF PROMOTER AND PHYSICO-CHEMICAL PROPERTIES OF METAL OXIDE CATALYSTS |
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This study reports improved catalytic activities and stabilities for the oxidation of dimethyl sulfide (DMS), a major pollutant of pulp and paper mills. Ozone was used as an oxidan...
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CHANGES IN MITOGEN-ACTIVATED PROTEIN KINASE IN CEREBELLAR GRANULE NEURONAL CULTURES BY POLYBROMINATED DIPHENYL ETHERS. |
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Polybrominated diphenyl ethers (PBDEs) are used as additive flame-retardants and have been detected in human blood, adipose tissue, and breast milk; clarifying the nature of the ri...
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CHANGES IN MRNA EXPRESSION PROFILES IN RAT CORTEX AND STRIATUM FOLLOWING SUB CHRONIC TOLUENE EXPOSURE. |
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Toluene, a volatile organic compound (VOC) used in many commercial products, is a ubiquitous air pollutant and therefore of interest to many EPA regulatory programs. A primary con...
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CHAPTER 4. Application of Genomics to Regulatory Ecological Risk Assessments for Pesticides |
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Development of conceptual framework concerning how genomic data could effectively impact different types of ecological risk assessments in both the short and long term....
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CHARACTERIZATION OF CYPS IN THE METABOLISM OF ALL TRANS RETINOIC ACID BY LIVER MICROSOMES FROM MICE TREATED WITH CONAZOLES |
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Conazoles are fungicides used in crop protection and as pharmaceuticals. Triadimefon and propiconazole are hepatotumorigenic in mice, while myclobutanil is not. Previous toxicogeno...
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CHARACTERIZATION OF LOCOMOTOR ACTIVITY OF ZEBRAFISH LARVAE: TEMPORAL VARIABILITY AND PHOTORESPONSE. |
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As part of EPA’s effort to develop a rapid, in vivo, vertebrate screen for toxic chemicals, we have begun research to characterize the locomotor activity of 6-day post-fertilizati...
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CHARACTERIZATION OF NEAR-ROAD POLLUTANT GRADIENTS USING PATH-INTEGRATED OPTICAL REMOTE SENSING |
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Understanding motor vehicle emissions, near roadway pollutant dispersion, and their potential impact to near roadway populations is an area of growing interest. A field study was c...
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CHILD-SPECIFIC EXPOSURE FACTORS HANDBOOK (2008) |
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The National Center for Environmental Assessment Staff have prepared this handbook to provide information on various physiological and behavioral factors commonly used in assessing...
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CHLORPYRIFOS TRANSFORMATION BY AQUEOUS CHLORINE IN THE PRESENCE OF BROMIDE AND NATURAL ORGANIC MATTER |
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The aqueous chlorination of chlorpyrifos (CP) was investigated in the presence of bromide and natural organic matter (NOM), which were identified as naturally occurring aqueous con...
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CLIMATE CHANGE EFFECTS ON STREAM AND RIVER BIOLOGICAL INDICATORS: A PRELIMINARY ANALYSIS (FINAL REPORT) |
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This final report is a preliminary assessment that describes how biological indicators are likely to respond to climate change, how well current sampling schemes may detect climat...
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CO-DEPENDENCIES OF REACTIVE AIR TOXIC AND CRITERIA POLLUTANTS ON EMISSION REDUCTIONS |
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It is important to understand the effect of emission controls on the concentrations of ozone, PM2.5, and hazardous air pollutants simultaneously, in order to evaluate th...
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COASTAL SALT MARSH COMMUNITY CHANGE IN NARRAGANSETT BAY IN RESPONSE TO CULTURAL EUTROPHICATION |
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Coastal salt marshes are susceptible to cultural eutrophication, particularly the over-enrichment of nitrogen, because they are often located where surface water and groundwater d...
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COLLECTION OF AMBIENT PARTICULATE MATTER BY POROUS VEGETATION BARRIERS: SAMPLING AND CHARACTERIZATION METHODS |
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This manuscript describes work done by A. Reff as part of a collaboration begun 3 years ago at Rutgers University with A. Tiwary who was then at the University of Nottingham. The ...
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COMPARABILITY OF A REGIONAL AND STATE SURVEY: EFFECTS ON FISH IBI ASSESSMENT FOR WEST VIRGINIA, U.S.A. |
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The comparability of different survey designs needs to be established to facilitate integration of data across scales and interpretation of trends over time. Probability-based su...
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COMPARING HPLC-ESI-ITMS AND UPLC-ESI-OA-TOF-MS IN CHARACTERIZING MACROLIDE ANTIBIOTICS AND ILLICIT DRUGS IN COMPLEX ENVIRONMENTAL MATRICES |
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Among the challenges of characterizing emerging contaminants in complex environmental matrices (e.g., biosolids, sewage, or wastewater) are the co-eluting interferences. For exampl...
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COMPARISON OF NEUROSCREEN-1 AND CEREBELLAR GRANULE CELL CULTURES FOR EVALUATING NEURITE OUTGROWTH USING THE ARRAYSCAN HIGH CONTENT ANALYSIS SYSTEM |
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A major challenge facing the Environmental Protection Agency is the development of high-throughput screening assays amendable to resource-efficient developmental neurotoxicity for ...
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COMPLEMENTARY MOLECULAR AND ELEMENTAL DETECTION OF SPECIATED THIOARSENICALS USING ESI-MS IN COMBINATION WITH A XENON-BASED COLLISION-CELL ICP-MS WITH APPLICATION TO FORTIFIED NIST FREEZE-DRIED URINE |
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The simultaneous detection of arsenic and sulfur in thio-arsenicals was achieved using xenonbased collision cell ICP-MS in combination with HPLC. In an attempt to minimize the 16O1...
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COMPLETE INHIBITION OF SPONTANEOUS ACTIVITY IN NEURONAL NETWORKS IN VITRO BY DELTAMETHRIN AND PERMETHRIN |
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Type I and II pyrethroid insecticides cause temporally distinct decreases in voltage-gated sodium channel (VGSC) inactivation rates that are proposed to underlie their characterist...
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CONCENTRATION AND TREATMENT OF DRINKING WATERS IN THE FOUR LAB STUDY |
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The purpose of the four lab study was to address concerns related to potential health effects from exposure to complex mixtures of DBPs that cannot be addressed directly from toxic...
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COUPLED BIOLOGICAL-PHYSICAL PROCESSES AFFECTING HYPOXIA IN THE NORTHERN GULF OF MEXICO |
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Abstract for presentation...
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COUPLING SATELLITE BIO-OPTICS, NUMERICAL MODELS AND OBSERVATIONS TO DEFINE A COASTAL ECOSYSTEM. |
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Abstract for presentation...
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CROSS-SPECIES COMPARISON OF CONAZOLE FUNGICIDE METABOLITES USING RAT AND RAINBOW TROUT (ONCHLORHYNCHUS MYKISS) HEPATIC MICROSOMES AND PURIFIED HUMAN CYP 3A4 |
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Ecological risk assessment frequently relies on cross-species extrapolation to predict acute toxicity from chemical exposures. A major concern for environmental risk characterizati...
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Calculating Henry’s Constants of Charged Molecules Using SPARC |
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SPARC Performs Automated Reasoning in Chemistry is a computer program designed to model physical and chemical properties of molecules solely based on thier chemical structure. SPAR...
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Can Soft Water Limit Bighead Carp and Silver Carp (Hypophthalmichthys spp.) Invasions? |
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There is concern that the non-native bighead carp (Hypophthalmichthys nobilis) and silver carp (H. molitrix), now found in many large rivers of the Mississippi River Basin, may spr...
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Carcinogenicity and Mutagenicity Data: New Initiatives to Improve Access and Utility for Modeling |
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Currents models for prediction of chemical carcinogenicity and mutagenicity rely upon a relatively small number of publicly available data resources, where the data being modeled a...
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Cardiac and vascular changes in mice after exposure to ultrafine particulate matter |
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Increased ambient air particulate matter (PM) concentrations are associated with risk for myocardial infarction, stroke, and arrhythmia, and ultrafine PM (UFPM) might be particular...
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Cardiopulmonary responses of intratracheally instilled tire particles and constituent metal components |
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Exposure to near road particulate matter (PM) has been associated with adverse cardiopulmonary health. Tire and brake wear contain transition metals, and contribute to near road PM...
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Careers Other Than Academia EPA/AAAS Graduate Fellowship Expo |
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NCER invited Emilie to speak to the EPA STAR graduate fellows about her transition from graduate school into a postdoctoral position with the EPA. Discussion of what led Emilie to...
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Chapter 7. Toxicogenomics in Ecological Risk Assessments: A Prospectus |
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Development of conceptual framework concerning how genomic data could effectively impact different types of ecological risk assessments in both the short and long term....
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Chapter I. Toxicogenomics in Ecological Risk Assessments: Regulatory Context, Technical Background, and Workshop Overview |
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Development of conceptual framework concerning how genomic data could effectively impact different types of ecological risk assessments in both the short and long term....
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Characterization Of Environmentally Relevant Chemical And Physical Properties Of Silver Nano-Particles |
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Understanding and predicting the fate and transport of nano-materials in the environment requires a detailed characterization of the chemical and physical properties that control f...
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Characterization of neural development in zebrafish embryos using real-time quantitative PCR. |
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Chemicals adversely affecting the developing nervous system may cause long-term consequences on human health. Little information exists on a large number of environmental compounds...
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Characterization of nuclear microsatellite markers from Agrostis species |
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Agrostis stolonifera L. (creeping bentgrass) is a widely distributed, out-crossing, wind-pollinated, perennial grass that has been genetically engineered for a variety of traits in...
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Characterizing Air Pollution in Two Low-Income Neighborhoods in Accra, Ghana |
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Sub-Saharan Africa has the highest rate of urban population growth in the world, with a large number of urban residents living in low-income “slum” neighborhoods. We conducted a st...
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Characterizing Aqueous Fullerene Suspensions |
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Over 500 products purporting to contain nanoscale materials were on the market in 2007 and projections have suggested that the market for nanomaterial-containing products could rea...
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Characterizing Fullerene Nanoparticles in Aqueous Suspensions |
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Studies have indicated that fullerenes can form stable colloidal suspensions in water when introduced to the aqueous phase through solvent exchange, sonication, or extended mixing....
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Chemical Analysis of Drinking Water Concentrates in the Four Lab Study |
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The purpose of the Four Lab study was to evaluate potential health effects from exposure to disinfection by-products (DBPs). Unchlorinated water taken from a full-scale drinking w...
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Chemistry and Long-Term Decomposition of Roots of Douglas-Fir Grown under Elevated Atmospheric Carbon Dioxide and Warming Conditions |
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Elevated atmospheric CO2 concentrations and warming may affect the quality of litters of forest plants and their subsequent decomposition in ecosystems, thereby potentially affecti...
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Chloride dynamics in a restored urban stream and the influence of road salts on water quality |
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Understanding the connection between road salts and water quality is essential to assess the implications for human health and ecosystem services from these widely used de-icers. ...
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Chlorine decay and DBP formation under different flow regions in PVC and ductile iron pipes: Preliminary results on the role of flow velocity and radial mass transfer |
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A systematic experimental study was conducted using a pilot-scale drinking water distribution system simulator to quantify the effect of hydrodynamics, total organic carbon (TOC), ...
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Classification of Chemicals Based On Structured Toxicity Information |
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Thirty years and millions of dollars worth of pesticide registration toxicity studies, historically stored as hardcopy and scanned documents, have been digitized into highly standa...
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Cold Shock Exoribonuclease R(VacB) is involved in Aeromonas hydrophila Virulence |
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In this study, we cloned and sequenced a virulence-associated gene (vacB) from a clinical isolate SSU of Aeromonas hydrophila. We identified this gene based on our recently annotat...
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Coldwater fishes and thernal refuges in hot water: Synthesis and future directions |
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Characterizing spatial and temporal variability of thermal refuges used by coldwater fishes is increasingly becoming important for researchers and water resources practitioners see...
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Combining Existing Monitoring Sites with a Probability Survey Design - Examples from U.S. EPA’s National Coastal Assessment |
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U.S. Environmental Protection Agency’s (EPA’s) National Coastal Assessment was envisioned as a research effort led by EPA’s Office of Research and Development to evaluate assessmen...
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Combining Existing Monitoring Sites with a Probability Survey Design-Examples from U.S. EPA's National Coastal Assessment |
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U.S. Environmental Protection Agency's (EPA's) National Coastal Assessment was envisioned as a research effort led by EPA's Office of Research and Development to evaluate assessmen...
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Combining correlated stressor variables to clarify stressor effects |
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The effects of different stressors on biota cannot be clearly compared when stressor variables are sufficiently correlated in aquatic survey data. The recent USA Wadeable Streams A...
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Comparative Absorption and Bioaccumulation of Polybrominated Diphenyl Ethers following Ingestion via Dust and Oil in Male Rats |
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Household dust has been implicated as a major source of polybrominated diphenyl ether (PBDE) exposure in humans. This finding has important implications for young children, who te...
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Comparative Mammalian Cell Toxicity of N-DBPs and C-DBPs |
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In order to generate a quantitative, direct comparison amongst classes of drinking water disinfection by-products (DBPs), we developed and calibrated in vitro mammalian cell cytoto...
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Comparing Chitin And Organic Substrates On The National Tunnel Waters In BlackHawk, Colorado For Manganese Removal - (Presentation) |
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The National Tunnel is a part of the Central City/Idaho Springs Superfund site. Because passive treatment is an important possibility for removal of contaminants from the water, ...
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Comparing Environmental Influences on Coral Bleaching Across and within Species using Clustered Binomial Regression |
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Differential susceptibility among reef-building coral species can lead to community shifts and loss of diversity as a result of temperature-induced mass bleaching events. However,...
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Comparing Pharmacokinetic Models for Perfluorooctanoic Acid Mice |
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Perfluorooctanoic acid (PFOA) is environmentally persistent and widely detected in humans and wildlife. Model camparison was demonstrated in this presentation...
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Comparing Surface Residue Transfer Efficiencies to Hands Using Polar and Non-Polar Florescent Tracers |
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Results of this study indicate that dermal loadings of both tracers increase through the seventh brief contact. Dermal loading of Uvitex tends to increase at a higher rate than de...
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Comparing trophic position of stream fishes using stable isotope and gut contents analyses |
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Stable isotope analysis (SIA) and gut content analysis (GCA) are commonly used in food web studies, but few studies analyze these data in concert. We used SIA and GCA to identify d...
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Comparison of 85KR and 3H Apparent Ground-Water Ages for Source Water Vulterability in the COLLYER RIVER CATCHMENT, MAINE |
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Apparent ground-water ages as determined by the noble gas isotope 85Kr and the water isotope 3H are compared. Refined gas extraction methodology at the wellhe...
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Comparison of Arsenic Concentrations in Carcass and Viscera of Swim-up Rainbow Trout Exposed to Dietary and Waterborne Arsenic |
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Rainbow trout fry were exposed to arsenic in water only, diet only, or both diet and water in 28-d studies evaluating survival and growth. Diets consisted of Lumbriculus variegatu...
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Comparison of Species Sensitivity Distributions Derived from Interspecies Correlation Models to Distributions used to Derive Water Quality Criteria |
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Species sensitivity distributions (SSD) require a large number of measured toxicity values to define a chemical’s toxicity to multiple species. This investigation comprehensively e...
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Comparison of cell type specificities of stress pathway reporter assay ensemble response to environmental chemicals. |
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The large number of environmental compounds that currently need characterization and prioritization for further toxicological study is a serious regulatory challenge facing the EPA...
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Completion of a Short-term Reproduction Test for Identifying Endocrine-Disrupting Chemicals |
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This abstract describes a short-term reproduction test with the fathead minnow designed to fulfill requirements associated with the current EDC screening program....
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Computational Model of Adrenal Steroidogenesis to Predict Biochemical Response to Endocrin Disruptors |
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Steroids, which have an important role in a wide range of physiological processes, are synthesized primarily in the gonads and adrenal glands through a series of enzyme mediated re...
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Computational Molecular Modeling for Evaluating the Toxicity of Environmental Chemicals: Prioritizing Bioassay Requirements |
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This commentary provides an overview of the challenges that arise from applying molecular modeling tools developed and commonly used for pharmaceutical discovery to the problem of ...
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Computational Steroidogenesis Model To Predict Biochemical Responses to Endocrine Active Chemicals: Model Development and Cross Validation |
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Steroids, which have an important role in a wide range of physiological processes, are synthesized primarily in the gonads and adrenal glands through a series of enzyme-mediated re...
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Computational Toxicology |
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A short article that discusses the growing research of computaional toxicology...
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Computational Toxicology (S) |
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The emerging field of computational toxicology applies mathematical and computer models and molecular biological and chemical approaches to explore both qualitative and quantitativ...
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Computational Toxicology - A State of the Science Mini Review |
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This mini-review is based on presentations and discussions at the International Science Forum on Computational Toxicology that was sponsored by the Office of Research and Developme...
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Conazole Fungicides as Chiral Environmental Contaminants: Enantiomer Analysis and Enantioselectivity in Soil Slurries |
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Conazoles are triazole compounds, many of which are in wide use as agricultural and medicinal fungicides. Opportunities exist for them to contaminate the environment and, since the...
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Concepts, Methods, and Data Sources for Cumulative Health Risk Assessment of Multiple Chemicals, Exposures and Effects: A Resource Document (Final Report) |
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This final report is a resource document that provides concepts, methods and data sources to assist in the conduct of multi-chemical, population-focused cumulative risk assessments...
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Concordance in Genomic Changes Between Mouse Lungs and Human Airway Epithelial Cells Exposed to Diesel Exhaust Particles |
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Human and animal toxicity studies have shown that exposure to diesel exhaust particles (DEP) or their constituents affect multiple biological processes including immune and inflamm...
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Condition Assessment of Drinking Water Transmission and Distribution Systems |
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Condition assessment of water transmission and distribution mains is the collection of data and information through direct and/or indirect methods, followed by analysis of the data...
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Conditional Probability Analysis: A Statistical Tool for Environmental Analysis. |
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The use and application of environmental conditional probability analysis (CPA) is relatively recent. The first presentation using CPA was made in 2002 at the New England Associati...
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Consequences of tetracycline exposure to stream periphyton in an experimental mesocosm study |
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A significant amount of ingested, injected, and applied antibiotics are not metabolized but are excreted; entering the environment via point and non-point sources. Tetracycline an...
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Considering Environment, Economy, And Society In Land-Use: A Case Study - Stella, Missouri |
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Human life is conditional upon intact ecosystems that provide goods and services required to sustain human life. Because development will incrementally and cumulative consume the ...
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Constructed Wetlands for Wastewater Treatment |
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This presentation is a general introductory overview of constructed wetlands for wastewater treatment. Photographs show a wide range of applications and sizes. Summary data on co...
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Contributions from Remote Sensing to Policy Development Related to Genetically Modified Crops in US Agriculture |
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In recent years, the use of Plant Incorporated Protectant (PIP) maize by American producers has been increasing dramatically....
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Control Strategy for Storm-Generated Sanitary Sewer Overflows |
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This presentation covers a strategy for the abatement of pollution from sanitary-sewer overflows (SSO). Because of the great lengths of sanitary sewer systems, it is often less exp...
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Coordinated changes in xenobiotic metabolizing enzyme (XME) gene expression through the life stages of the male C57BL/6 mouse |
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Metabolic homeostasis of the organism is maintained by the liver's ability to detoxify and eliminate xenobiotics. This is accomplished, in part, by the expression of XMEs, which me...
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Correlation of carbon isotope ratios in the cellulose and wood extractives of Douglas-fir |
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Cellulose is usually isolated from the other components of plant material for analysis of carbon stable isotope ratios (δ13C). However, many studies have shown a strong correlation...
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Cryptosporidium Source Tracking in the Potomac River Watershed |
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To better characterize the presence of Cryptosporidium in the Potomac River watershed, a PCR-based genotyping tool was used to analyze 64 base-flow and 28 storm-flow samples from f...
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Current Research at EPA's Urban Watershed Research Facility |
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Description of current research and approaches at the U.S. EPA's Urban Watershed Research Facility....
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DECISION SUPPORT TOOL FOR EVALUATING VULNERABILITY TO HAZARDOUS AIR POLLUTANTS IN THE SOUTHEAST |
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Valued ecological endpoints such as threatened and endangered species and critical habitat are often evaluated for proximate impacts such as nearby development and direct impacts s...
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DELTAMETHRIN AND ESFENVALERATE INHIBIT SPONTANEOUS NETWORK ACTIVITY IN RAT CORTICAL NEURONS IN VITRO. |
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Understanding pyrethroid actions on neuronal networks will help to establish a mode of action for these compounds, which is needed for cumulative risk decisions under the Food Qual...
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DESIGN AND EVALUATION OF AN INLET CONDITIONER TO DRY PARTICLES FOR AN AERODYNAMIC PARTICLE SIZER |
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Atmospheric particulate matter is one of six pollutants for which the Environmental Protection Agency (EPA) has set National Ambient Air Quality Standards. Particulate matter stan...
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DESIGN CONSIDERATION INVOLVING ACTIVE SEDIMENT CAPS (PRESENTATION) |
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When contaminated sediments pose unacceptable risks to human health and the environment, management activities such as removal, treatment, or isolation of contaminated sediments ma...
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DETECTING BENTHIC COMMUNITY DIFFERENCES: INFLUENCE OF STATISTICAL INDEX AND SEASON |
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An accurate assessment of estuarine condition is critical to determining whether there has been a change from baseline or 'natural' conditions; benthic communities are routinely us...
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DETECTION OF STACHYBOTRYS CHARTARUM USING rRNA, tri5, AND Β-TUBULIN PRIMERS AND DETERMINING THEIR RELATIVE COPY NUMBER BY REAL TIME PCR |
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This research utilizes the quantitative polymerase chain reaction (qPCR) to determine ribosomal copy number of fungal organisms found in unhealthy indoor environments. Knowing spe...
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DETERMINATION OF THE POTENTIAL FOR ANAEROBIC DEGRADATION OF UNUSED PHARMACEUTICALS IN MUNICIPAL SOLID WASTE LANDFILLS |
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For many years the recommended method of disposal for unused household medications was the sewage system. However, research studies have emerged showing that many pharmaceuticals ...
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DEVELOPING AND IMPLEMENTING AN UPDATED CHLORINE CHEMISTRY INTO THE COMMUNITY MULTISCALE AIR QUALITY MODEL |
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The study presents an updated chlorine mechanism and evaluates the effects of chlorine emissions on ozone concentrations in the western United States. ...
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DEVELOPING METHODS FOR EMERGING CONTAMINANTS IN BIOSOLIDS |
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There is no abstract available for this product. If further information is requested, please refer to the bibliographic citation and contact the person listed under Contact Field....
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DEVELOPING WATER QUALITY CRITERIA FOR SUSPENDED AND BEDDED SEDIMENTS |
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The U.S. EPA’s Framework for Developing Suspended and Bedded Sediments (SABS) Water Quality Criteria (SABS Framework) is a nationally-consistent process for developing ambient sedi...
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DEVELOPMENT AND APPLICATION OF PLANNING PROCESS TO ACHIEVE SUSTAINABILITY |
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Concepts of sustainability are numerous, widely discussed, and necessary, but sustainability needs to be applied to development projects to succeed. However, few applications are ...
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DEVELOPMENT AND TEST APPLICATION A SCREENING-LEVEL MERCURY FATE MODEL AND TOOL FOR EVALUATING WILDLIFE EXPOSURE RISK FOR SURFACE WATERS WITH MERCURY-CONTAMINATED SEDIMENTS (SERAFM) |
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Complex chemical cycling of mercury in aquatic ecosystems means that tracing the linkage between anthropogenic and natural loadings of mercury to watersheds and water bodies and as...
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DEVELOPMENT OF A PHYSIOLOGICALLY-BASED PHARMACOKINETIC (PBPK) MODEL FOR THE INHALATION OF 2,2,4-TRIMETHYLPENTANE (TMP) IN LONG EVANS RATS. |
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TMP (2,2,4-trimethylpentane,“isooctane”) is a colorless liquid used primarily in the alkylation of isobutene and butylene reactions to derive high-octane fuels. TMP is released in ...
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DEVELOPMENT OF AN OBJECTIVE AND QUANTIFIABLE TERATOLOGICAL SCREEN FOR USE IN ZEBRAFISH LARVAE. |
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To address EPA’s need to prioritize large numbers of chemicals for testing, a rapid, cost-effective in vivo screen for potential developmental toxicity using an alternative vertebr...
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DEVELOPMENT OF MARKERS OF EXPOSURE TO COPPER, NONYLPHENOL AND ATRAZINE USING SUTRACTIVE HYBRIDIZATION |
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Daphnia have been among the most commonly used test organisms for aquatic toxicity studies due to their sensitivity to contaminants. This sensitivity makes them excellent candidate...
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DEVELOPMENT OF NORMAL HUMAN COLON CELL CULTURES TO IDENTIFY UNREGULATED DISINFECTION BY-PRODUCTS (DBPS) WITH CARCINOGENIC POTENTIAL. |
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Epidemiological studies have linked the consumption of chlorinated surface waters to an increased risk of colorectal cancer. Approximately 600 DBPs, less than half of the total org...
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DEVELOPMENTAL TOXICOGENOMIC STUDIES OF PFOA AND PFOS IN MICE. |
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Perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) are developmentally toxic in rodents. To better understand the mechanism(s) associated with this toxicity, we ha...
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DIESEL EXHAUST EXPOSURE INCREASES SEVERITY OF AN ONGOING INFLUENZA INFECTION |
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Numerous studies have shown that air pollutants including diesel exhaust (DE) alter host defense responses, resulting in decreased resistance to respiratory infection. The purpose...
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DIFFERENCES IN ALLERGENIC POTENTIAL OF FOOD EXTRACTS FOLLOWING ORAL EXPOSURE IN MICE REFLECT DIFFERENCES IN DIGESTIBILITY: POTENTIAL APPROACHES TO SAFETY ASSESSMENT |
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An animal model for food allergy is needed to assess genetically modified food crops for potential allergenicity. The ideal model must produce allergic antibody (IgE) to proteins ...
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DIFFERENCES IN METABOLISM AND AROMATASE ACTIVITY IN A FISH AND A RAT SPECIES TREATED WITH ATRAZINE |
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Poster presentation as a scientific conference...
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DIFFERENTIAL CARDIAC ARRHYTHMIA PROFILES IN HYPERTENSIVE AND NORMAL RATS AFTER EMISSION SOURCE PARTICULATE EXPOSURE |
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Exposure to combustion-derived fine particulate air pollution is associated with increased cardiovascular morbidity and mortality. These effects are especially conspicuous in ind...
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DIFFERENTIAL GROWTH RATES OF SYMBIODINIUM ISOLATES EXPOSED TO THE COMBINED EFFECTS OF ELEVATED TEMPERATURE AND ULTRAVIOLET RADIATION |
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Abstract ...
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DISCARDED DRUGS AS ENVIRONMENTAL CONTAMINANTS |
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There is no abstract available for this product. If further information is requested, please refer to the bibliographic citation and contact the person listed under Contact Field....
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DISCARDED DRUGS AS ENVIRONMENTAL CONTAMINANTS (1) |
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Presentation materials. If further information is requested, please refer to the bibliographic citation and contact the person listed under Principal Investigator....
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DISCARDED DRUGS AS ENVIRONMENTAL CONTAMINANTS (2) |
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Presentation materials. If further information is requested, please refer to the bibliographic citation and contact the person listed under Prinicpal Investigator....
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DISINFECTION PROCESSES AND STABILITY REFINEMENTS TO BIOSOLIDS TREATMENT TECHNOLOGIES |
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This paper reviews the current US sewage sludge disinfection regulations and their associated practices; discusses the limitations of the practices; discusses the criteria employed...
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DISPERSANT EFFECTIVENESS ON OIL SPILLS - EMPIRICAL CORRELATIONS |
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When a dispersant is applied to an oil slick, its effectiveness in dispersing the spilled oil depends on various factors such as oil properties, wave mixing energy, temperature of ...
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DNA Microarray-based Ecotoxicological Biomarker Discovery in a Small Fish Model Species |
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This paper addresses several issues critical to use of zebrafish oligonucleotide microarrays for computational toxicology research on endocrine disrupting chemicals using small fis...
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DOES RESPONSE EVALUATION OF GENE EXPRESSION PROFILES IN THE SKIN OF K6/ODC MICE EXPOSED TO SODIUM ARSENITE |
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Abstract - Chronic drinking water exposure to inorganic arsenic and its metabolites increases tumor frequency in the skin of K6/ODC transgenic mice. To identify potential biomarke...
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DOSE-DEPENDENT DISTRIBUTION AND ELIMINATION OF CIS- AND TRANS-PERMETHRIN IN THE RAT |
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Pyrethroids are neurotoxic insecticides used in a variety of agricultural and household activities. Due to the phase-out of organophosphate pesticides, use of pyrethroids has incr...
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DRUG EFFECTS ON THE LOCOMOTOR ACTIVITY OF LARVAL ZEBRAFISH. |
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As part of an effort to develop a rapid in vivo screen for EPA’s prioritization of toxic chemicals, we have begun to characterize the locomotor activity of zebrafish (Danio rerio) ...
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DYNAMIC EVALUATION OF REGIONAL AIR QUALITY MODELS: ASSESSING CHANGES TO O 3 STEMMING FROM CHANGES IN EMISSIONS AND METEOROLOGY |
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Regional-scale air quality models are used to estimate the response of air pollutants to potential emission control strategies as part of the decision-making process. Traditionally...
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DYNAMICS OF PHYTOPLANKTON, DETRITUS, AND COLORED DISSOLVED ORGANIC MATTER IN HYPOXIC AND NON-HYPOXIC GULF OF MEXICO WATERS. |
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Abstract for presentation...
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Data for Environmental Modeling (D4EM): Background and Applications of Data Automation |
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The Data for Environmental Modeling (D4EM) project demonstrates the development of a comprehensive set of open source software tools that overcome obstacles to accessing data neede...
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Data-derived uncertainty factor approach in the revised N-methyl carbamate risk assessment. |
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EPA completed its Revised Cumulative Risk Assessment (CRA) of the N-methyl Carbamate (NMC) Pesticides in 2007. This assessment evaluated the joint risk to 10 pesticides from food, ...
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Delineating resource sheds in aquatic ecosystems (presentation) |
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Analysis of spatially-explicit ecological phenomena in aquatic ecosystems is impeded by a lack of knowledge of, and tools to delimit, spatial patterns of material supply to point l...
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Denitrification Potential, Root Biomass and Organic Matter in Degraded and Restored Urban Riparian Zones |
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Hydrologic changes associated with urbanization often lead to lower water tables and drier, more aerobic soils in riparian zones. These changes
reduce the potential for denitrifi...
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Description of Drinking Water Bacterial Communities Using 16S rRNA Gene Sequence Analyses |
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Descriptions of bacterial communities inhabiting water distribution systems (WDS) have mainly been accomplished using culture-based approaches. Due to the inherent selective nature...
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Detection and Quantification of Human Fecal Pollution with Real-Time PCR |
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ABSTRACT
Assessment of health risk and fecal bacteria loads associated with human fecal pollution requires a reliable host-specific genetic marker and a rapid quantification meth...
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Detection of Mycobacterium avium subsp. paratuberculosis in Drinking Water and Biofilms Using Quantitative PCR |
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Mycobacterium avium subsp. paratuberculosis (MAP) causes Johne’s disease in domestic animals and has been implicated in Crohn’s disease in humans. Cows infected with Johne’s diseas...
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Deteriorating Coastal Salt Marshes - Lessons Learned |
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Noticeable changes in structure and function in some Narragansett Bay, RI and Jamaica Bay, NY coastal salt marshes support the idea that “tipping points” in these ecosystems have b...
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Determination of Perfluorocarboxylic Acids in Sludge |
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Methods were developed for the extraction from wastewater-treatment sludge and quantitation by LC/MS/MS of perfluorocarboxylic acids (PFCAs, C6 to C12), 7-3 fluorotelomer carboxyli...
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Determining the Ecosystem Services Important for Urban Landscapes |
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Urban ecosystems present special considerations and challenges in researching and evaluating ecosystem functions and services. A case study of nitrate retention and loss in forest...
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Determining the Ecosystem Services Important for Urban Landscapes-Slides |
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This presentation consists of introductory slides on ecosystem services in urban landscapes and then a discussion of two case studies concerning the provision of water quality in u...
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Development of Benthic Indicators for Nearshore Coastal Waters of New Jersey - A REMAP Project |
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EPA's National Coastal Assessment (NCA) is providing the first complete, consistent dataset on the condition of benthic communities in the nation's estuaries. Prior to NCA, New Je...
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Development of Fire Emissions Inventory Using Satellite Data |
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There are multiple satellites observing and reporting fire imagery at various spatial and temporal resolutions and each system has inherent merits and deficiencies. In our study, ...
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Development of Mass Spectrometric Ionization Methods for Fullerenes and Fullerene Derivatives |
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Currently investigations into the environmental behavior of fullerenes and fullerene derivatives is hampered by the lack of well characterized standards and by the lack of readily ...
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Development of Quality Control Parameters and Electronic Data Recording for an Ambient Air Particle Inhalation Exposure System |
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Ambient air particle concentrating systems were installed by the US EPA in RTP, NC. These systems, designed by Harvard School of Public Health’s Department of Environmental Scienc...
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Development of Species Sensitivity Distributions for Wildlife Using Interspecies Toxicity Correlation Models |
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Species sensitivity distributions (SSD) are cumulative distributions of chemical toxicity of multiple species and have had limited application in wildlife risk assessment because o...
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Development of Thyroid Gland Specific Markers of Hypothalamic-pituitary-thyroid Axis Disruption in the Amphibian Model Species Xenopus laevis |
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The focus of the research presented here is the development of an in vitro thyroid gland culture system to test the effect of chemicals directly on the gland without influence of o...
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Development of Water Quality Modeling in the United States |
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This presentation describes historical trends in water quality model development in the United States, reviews current efforts, and projects promising future directions. Water qua...
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Development of Weighted Distributions of REPs for Dioxin-Like Compounds: Implications for Risk Assessment |
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In their recent reevaluation of the TEF methodology, the WHO expert panel indicated that consideration should be given to developing weighted distributions of REP values to establi...
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Development of a Biologically Based Dose Response (BBDR) Model for Arsenic Induced Cancer (S) |
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Discuss the development of a biologically based dose response (BBDR) model for arsenic carcinogenicity in order to reduce uncertainty in estimates of low dose risk by maximizing th...
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Development of a Biomass Burning Emissions by Combining Satellite and Ground-based Information |
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A 2005 biomass burning (wildfire, prescribed, and agricultural) emission inventory has been developed for the contiguous United States using a newly developed simplified method of ...
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Development of a Gas Chromatography/Mass Spectrometry Method for the Analysis of the Solvent Stabilizer 1,4-Dioxane in Drinking Water |
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The solvent stabilizer 1,4-dioxane was named to the latest draft Drinking Water Contaminant Candidate List (CCL3) in February 2008 by the United States Environmental Protection Age...
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Development of a High-throughput Method for Quantitating Thyroid Gland Folllicular Cell Hyperplasia in Amphibian Model Species Xenopus laevis |
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This abstract outlines new methods for the quantitation of thyroid follicular cell hyperplasia in amphibian model species Xenopus laevis....
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Development of a Microarray Detection Method for Waterborne Pathogens - MCEARD/BARB |
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Presentation at the Joint EPA and DHS Conference on Real-World Applications and Solutions for Microbial Risk Assessment in Bethesda, MD, April 8-10, 2008...
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Development of normal human colon cell cultures to identify priority unregulated disinfection byproducts with a carcinogenic potential |
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Epidemiological studies have linked the consumption of chlorinated surface waters to an increased risk of colorectal cancer. At present ~600 DBPs have been identified as the major...
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Development of rapid methods for measuring stream ecosystem functions |
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Oral presentation at the meeting of the West Virginia Coal Association, Charleston, WV....
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Developmental Immunotoxicity |
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Animal models suggest that the immature immune system is more susceptible to xenobiotics than the fully mature system, and sequelae of developmental immunotoxicant exposure may be ...
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Developmental exposure to a mixture of two mechanistically distinct antiandrogens results in cumulative adverse reproductive effects in adult male rats |
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Typically, toxicological studies have focused on the adverse effects from exposure to single chemicals. However, endocrine disrupting chemicals (EDCs) are detected in the environme...
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Developmental exposure to perchlorate alters synaptic transmission in hippocampus of the adult rat. |
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The Food Quality Protection Act and Safe Drinking Water Act mandate the EPA to identify potential health risks associated with chemicals that act on the endocrine system. Perchlora...
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Developmental neurotoxicity testing: Past, present and future. |
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Adverse effects on the nervous system following exposure to environmental contaminants during development have been well documented. Indeed, in a number of cases (e.g., lead, meth...
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Diagnosing Abiotic Degradation |
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The abiotic degradation of chlorinated solvents in ground water can be difficult to diagnose. Under current practice, most of the “evidence” is negative; specifically the apparent...
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Diagnostic Analysis of the Three-Dimensional Sulfur Distributions over the Eastern United States Using the CMAQ Model and Measurements from the ICARTT Field Experiment |
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Previous comparisons of air quality modeling results from various forecast models with aircraft measurements of sulfate aerosol collected during the ICARTT field experiment indicat...
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Diesel exhaust particles induce the over expression of tumor necrosis factor-alpha (TNF-alpha) gene in alvelor machrophage and failed to induce apoptosis through activation of nuclear factor-kappaB (NF-kappaB) |
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Exposure to particulate matter (PM2.5-10), including diesel exhaust particles (DEP) has been reported to induce lung injury and exacerbation of asthma and chronic obstructive pulmo...
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Diet and nutrition of western rock lobsters, Panulirus cygnus, in shallow coastal waters: the role of habitat |
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Generalist consumers often have diets that vary considerably over time and space, which reflects changes in resource availability. Predicting diets of consumers can therefore be di...
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Dietary Uptake Models Used for Modeling the Bioaccumulation of Organic Contaminants in Fish |
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Numerous models have been developed to predict the bioaccumulation of organic chemicals in fish. Although chemical dietary uptake can be modeled using assimilation efficiencies, bi...
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Differential Effects of Solar Ultraviolet Radiation on Culturable Enterococcus faecalis and Enterococcus DNA Determined Using Real-time Quantitative PCR |
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Biological contamination of aquatic environments by pathogenic microorganisms is often assessed using fecal indicator bacteria such as enterococci. The concentrations of enterococc...
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Discontinuities reveal panarchy in socio-ecological system |
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Debates on the organization, structure and dynamics of ecosystems across scales of space and time have waxed and waned in the literature for a century. From successional theory to...
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Do You Know What's in Your Drinking Water? Uncovering New Disinfection By-Products |
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Slide presentation on drinking water disinfection by-products. There is no abstract for this product. If further information is requested, please refer to the bibliographic citatio...
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Do post-mining constructed channels replace functional characteristics of headwater streams? |
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Mountaintop mining and valley fill (MTMVF) is a method of coal mining common in eastern Kentucky and southern West Virginia. Over 1200 miles of stream channel have been buried by M...
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Documenting taxonomic data quality for field fish identifications: a proposal for national surveys |
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The U.S. Environmental Protection Agency is in the midst of a multiyear series of natinal surveys of water resource conditions. Because communicating ecological condition is the pr...
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Does Terrestrial Carbon Subsidize Production of Estuarine Fish Larvae? |
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The study shows important connections between terrestrial, riverine and marine energy sources in supporting larval fish production across an estuarine ecosystem in Chesapeake Bay, ...
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Does encouraging the use of wetlands in water quality trading programs make economic sense? |
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Water quality trading has grown in popularity and scope in recent years owing to its potential as a flexible, low-cost way to achieve nutrient reduction goals. Policy makers are i...
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Does temperature structure phytoplankton community composition in the Ross Sea, Antarctica? |
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The Ross Sea polynya experiences one of the largest phytoplankton blooms in the Southern Ocean. Energy flow potential within the Ross Sea food web is primarily set by diatoms and p...
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Drinking Water Contaminants Research Findings |
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The presentation provides a short summary of the USEPA arsenic removal demonstration program. The summary included the results of the arsenic demonstration project in Arnaudville,...
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Dynamic river networks as the context for evaluating riparian influence on river basin solute export |
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Many studies have examined the influence of riparian areas on nitrogen as water drains from hillslopes and through riparian zones at the stream reach scale. Most of these studies h...
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EFFECT OF AGING ON THE CARDIOVASCULAR AND THERMOREGULATORY RESPONSE TO TOLUENE IN THE BROWN NORWAY RATS. |
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Since the proportion of aged in the U.S. will expand markedly for the next several decades, the U.S.EPA is assessing if the aged are more susceptible to environmental toxicants. Th...
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EFFECTS OF EROSION AND MACROALGAE ON INTERTIDAL EELGRASS (ZOSTERA MARINA) IN A NORTHEASTERN PACIFIC ESTUARY (USA) |
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Eelgrass (Zostera marina) in open-coast northeastern Pacific estuaries is primarily intertidal, yet little research has been done on the natural factors controlling its upper inter...
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EFFECTS OF HABITAT LOSS ON POPULATIONS OF WHITE-FOOTED MICE: MATRIX MODEL PREDICTIONS WITH LANDSCAPE-SCALE PERTURBATION EXPERIMENTS |
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Habitat loss is the leading cause of decline in wildlife diversity and abundance throughout the world, and understanding its impacts on animal populations is a critical challenge f...
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EFFECTS OF HYPOXIA ON ANIMAL BURROW CONSTRUCTION AND CONSEQUENT EFFECTS ON SEDIMENT REDOX PROFILES (ASLO) |
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poster presentation at a scientific conference...
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EFFECTS OF SPATIAL EXTENT ON LANDSCAPE STRUCTURE AND SEDIMENT METAL CONCENTRATION RELATIONSHIPS IN SMALL ESTUARINE SYSTEMS OF THE US MID-ATLANTIC COAST |
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Prior studies exploring the quantitative relationship between landscape structure metrics and the ecological condition of receiving waters have used a variety of sampling units (e....
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EFFECTS OF THE VARIATION OF SELECT SAMPLING PARAMETERS ON SOIL VAPOR CONCENTRATIONS |
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Currently soil vapor surveys are commonly used as a screening technique to delineate subsurface volatile organic compound (VOC) contaminant plumes and to provide information for va...
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EFFECTS ON HEPATIC DEIODINASE 1 AND THYROID HORMONE LEVELS IN PERINATALLY EXPOSED RATS TO A PBDE COMMERCIAL MIXTURE |
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PBDE mixture, DE-71, mostly tetra- and penta-bromodiphenyl ethers had been commonly used as a flame retardant in polyurethane foam. These congeners are ubiquitous in the environme...
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EMERGING CONTAMINANTS IN BIOSOLIDS |
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Emerging contaminants are receiving increasing media and scientific attention. These chemicals are sometimes referred to as compounds of emerging concern or trace organic compound...
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ENANTIOSELECTIVE CHRONIC TOXICITY OF FIPRONIL TO CERIODAPHNIA DUBIA |
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Fipronil is a phenylpyrazole pesticide that has greatly increased in popularity in recent years. As a chiral molecule, fipronil is released into the environment as a 1:1 mixture (...
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ENCOURAGING THE USE OF DRIFT REDUCTION TECHNOLOGIES IN THE UNITED STATES |
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A number of pesticide application technologies offer the potential to reduce spray drift from pesticide applications. However, limited information exists on their effectiveness in ...
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ENDOCRINE DISRUPTING CHEMICAL RISK MANAGEMENT RESEARCH IN THE US EPA'S OFFICE OF RESEARCH AND DEVELOPMENT |
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Endocrine disrupting chemicals (EDCs) are receiving increasing media and scientific attention. Concerns about these chemicals stem from the possibility of serious human and wildli...
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ENVIRONMENTAL IMPACT ASSESSMENT TAXONOMY PROVIDING COMPREHENSIVE COVERAGE OF MIDPOINTS, ENDPOINTS, DAMAGES, AND AREAS OF PROTECTION |
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Prior to conducting a comprehensive impact assessment, such as a Life Cycle Impact Assessment (LCIA), there is a need to discuss the range of impacts which could and should be incl...
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ENVIRONMENTAL QUALITY AND LANDSCAPE-RISK ASSESSMENT IN THE YANTRA RIVER BASIN |
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Landscape characteristics exert their impact on the processes occurring in river basins in many directions and may influence in a different way the environmental security and some ...
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EPA Analysis for MAQC Toxicogenomics Datasets |
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Iconix Data Analysis -Multi-factorial Approach. 24 input training data sets (ITD) generated from the raw data using different methods....
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EPA DSSTox and ToxCast Project Updates: Generating New Data and Linkages in Support of Public Toxico-Cheminformatics Efforts |
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EPA’s National Center for Computational Toxicology is generating data and capabilities to support a new paradigm for toxicity screening and prediction. The DSSTox project is improv...
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EPA ORD's Role In Mine-Influenced Water-Treatment: Past, Present and Future |
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The purpose of this presentation is to describe the different technologies that the Office of Research and Development (ORD) of the U.S. Environmental Protection Agency has tested ...
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EPA Research Evaluating CAFO Impacts on Ground Water Quality |
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An overview of several projects will be presented on a research program currently underway at ORD’s Ground Water and Ecosystems Restoration Division (GWERD) to evaluate CAFO impact...
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EPA Workshop on Monitored Natural Attenuation for Inorganic Contaminants: 3 – Discussion of Specific Contaminants & Case Study |
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The purpose of this training is to present an overview of site characterization approaches to support evaluation of the potential for Monitored Natural Attenuation (MNA) as a remed...
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EPA ’s ECOLOGICAL MODELS FOR INTEGRATED WATERSHED MANAGEMENT |
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Aquatic ecological populations and communities are affected by the nature and quality of the water in which they live. Specific factors that affect instream biota include chemical ...
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EPA'S 2008 REPORT ON THE ENVIRONMENT (ROE) |
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The RoE presents information on environmental indicators in the areas of air, water, land, human health, and ecological condition. The report is available for download and the RoE...
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EPA's Ongoing Green Infrastructure Research |
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Green Infrastructure is a concept originating in the United States in the mid-1990's that highlights the importance of the natural environment in decisions about land use planning....
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EPA's ToxCast (TM) Program for Predicting Hazard and Prioritizing Toxicity Testing of Environmental Chemicals |
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EPA's ToxCast (TM) Program for Predicting Hazard and Prioritizing Toxicity Testing of Environmental Chemicals...
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EPA's ToxCast Program for Predicting Toxicity and Prioritizing Chemical Testing |
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Integrate modern computing and information technology with molecular biology to improve Agency prioritization of data requirements and risk assessment of chemicals...
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EPA's future midwestern landscapes (FML) study |
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EPA's ecological research program is initiating research to characterize ecosystem services and enable their routine consideration in environmental management and policy. The "Futu...
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EPA's future midwestern landscapes study |
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Overview of the future midwestern landscapes study at the annual meeting of the Soil Water Conservation Society, Tucson, Arizona, July 26-30, 2008....
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EPA's new research focus on ecosystem services, with a study of biofuels expansion in the Midwestern U.S. |
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EPA's Ecological Research Program is initiating new research to characterize ecosystem services and to enable their routine consideration in environmental management and policy. Re...
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EPAs ToxCast Program for Predicting Toxcity and Prioritizing Chemicals for Further Screening and Testing |
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Testing of environmental and industrial chemicals for toxicity potential is a daunting task because of the wide range of possible toxicity mechanisms. Although animal testing is on...
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EPAs ToxCast Research Program; Developing Predictive Bioactivity Signatures for Chemicals |
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The international community needs better predictive tools for assessing the hazards and risks of chemicals. It is technically feasible to collect bioactivity data on virtually all...
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EPA’s ToxCast Program for Predicting Hazard and Prioritizing the Toxicity Testing of Environmental Chemicals |
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An alternative is to perform a set of relatively inexpensive and rapid high throughput screening (HTS) assays, derive signatures predictive of effects or modes of chemical toxicity...
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ETV, LT2 and You: How the Environmental Technology Verification Program Can Assist with the Long Term 2 Enhanced Surface Water Treatment Rule |
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The Environmental Technology Verification (ETV) Drinking Water Systems (DWS) Center has verified the performance of treatment technologies that may be used by communities in meetin...
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EVALUATING PROBABILITY SAMPLING STRATEGIES FOR ESTIMATING REDD COUNTS: AN EXAMPLE WITH CHINOOK SALMON (Oncorhynchus tshawytscha) |
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Precise, unbiased estimates of population size are an essential tool for fisheries management. For a wide variety of salmonid fishes, redd counts from a sample of reaches are commo...
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EVALUATION AND LABORATORY VALIDATION OF THE CHEMICAL STANDARD ANALYTICAL PROTOCOL FOR EXTRACTABLE SEMIVOLATILE ORGANIC COMPOUNDS |
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There is no abstract available for this product. If further information is requested, please refer to the bibliographic citation and contact the person listed under Contact Field....
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EVALUATION OF ANALYTICAL REPORTING ERRORS GENERATED AS DESCRIBED IN SW-846 METHOD 8261A |
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SW-846 Method 8261A incorporates the vacuum distillation of analytes
from samples, and their recoveries are characterized by internal standards. The internal
standards measure re...
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EVALUATION OF HUMAN NEURAL PROGENITOR CELLS FOR DEVELOPMENTAL NEUROTOXICITY SCREENING: TIME COURSE OF EFFECTS ON CELL PROLIFERATION AND VIABILITY. |
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Current testing methods for developmental neurotoxicity (DNT) make evaluation of the effects of large numbers of chemicals impractical and prohibitively expensive. As such, we are ...
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EVALUATION OF SELECTED DNA-BASED TECHNOLOGY IN IMPAIRED WATERSHEDS IMPACTED BY FECAL CONTAMINATION FROM DIVERSE SOURCES |
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Fecal pollution of surface waters is a top reason for impairment, as listed by the U.S. Environmental Protection Agency’s report on the quality of the Nation's waters. To be able t...
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EVALUATION OF STREAMBANK RESTORATION ON IN-STREAM WATER QUALITY IN AN URBAN WATERSHED |
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The objectives of this on-going project are to: investigate the effectiveness of streambank restoration techniques on increasing available biological habitat and improving in-strea...
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EVALUATION OF THE COMMUNITY MULTISCALE AIR QUALITY (CMAQ) MODEL VERSION 4.5: UNCERTAINTIES AND SENSITIVITIES IMPACTING MODEL PERFORMANCE: PART I - OZONE |
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This study examines ozone (O3) predictions from the Community Multiscale Air Quality (CMAQ) model version 4.5 and discusses potential factors influencing the model resul...
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EVALUATION OF THE REMOVAL OF ESTROGENS FOLLOWING CHLORINATION |
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A number of estrogenic compounds have been shown to be present in surface waters in the U.S. These compounds have the potential to act as potent endocrine disrupting chemicals (ED...
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EVALUATION OF TOXICS IN RUNOFF FROM COATED SURFACES |
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Presented in this paper are results from a field and laboratory study of the potential runoff toxicity from coated surfaces. The study results qualified and quantified the types an...
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EXACERBATION OF ATHEROSCLEROSIS FOLLOWING EXPOSURE TO VARIOUS COMBUSTION SOURCE PARTICLES |
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Exposure of ApoE knockout (ApoE-/-) mice to concentrated ambient particles (CAPs) has been shown to increase arterial plaque area and size. CAPs are a complex aerosol mi...
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EXOTIC AND INVASIVE AQUATIC PLANTS IN GREAT LAKES COASTAL WETLANDS: DISTRIBUTION AND RELATION TO WATERSHED LAND USE AND PLANT RICHNESS AND COVER |
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This manuscript provides previously unavailable information to researchers and managers concerning exotic plants in the Great Lakes...This work arises out of our broader efforts to...
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EXPERIENCES WITH USING PROBABILISTIC EXPOSURE ANALYSIS METHODS IN THE U.S. EPA |
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Over the past decade various Offices and Programs within the U.S. EPA have either initiated or increased the development and application of probabilistic exposure analysis models. ...
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EXPOSURE OF AMPHIBIANS TO SEMI-VOLATILE ORGANIC COMPOUNDS IN THE SIERRA NEVADA MOUNTAINS AND CALIFORNIA CASCADES: RELATIONSHIP BETWEEN TADPOLE TISSUE AND SEDIMENT CONCENTRATIONS |
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Pesticides and other semi-volatile organic compounds (SOCs) undergo regional and longrange atmospheric transport. One such example is the transport of current-use pesticides from t...
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EXPRESSION PROFILING OF FIVE RAT STRAINS REVEAL TRANSCRIPTIONAL MODES IN THE ANTIGEN PROCESSING PATHWAY |
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Comparative gene expression profiling of rat strains with genetic predisposition to diverse cardiovascular diseases can help decode the transcriptional program that governs cellula...
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Ecological consequences of antibiotic exposure to periphyton in naturally colonizing stream mesocosms |
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Tetracycline and its derivatives are extensively used human and animal antibiotics, and enter stream ecosystems via point and non-point sources. Laboratory studies indicate that ...
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Ecosystem Restoration Research at GWERD |
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Ground Water and Ecosystems Restoration Division, Ada, OK Mission: Conduct research and technical assistance to provide the scientific basis to support the development of strat...
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Ecosystem Services Modeling Infrastructures: Simile/MIMES (Gund Institute) and FRAMES/3MRA (US EPA) Integrated Modeling for Forecasting |
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The Ecological Research Program (ERP) of the EPA Office of Research and Development has the vision of a comprehensive theory and practice for characterizing, quantifying, and valui...
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Ecosystem Services and Environmental Decision-Making |
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Presentation on ecosystem services and environmental decision-making....
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Ecosystem Services of Rivers |
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Presentation on ecosystem services of rivers for the National River Rally, May 2008, in Huron, OH....
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Ecosystem Services: New strategic focus for US EPA’s Ecological Research Program |
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U.S. EPA’s Office of Research and Development has made ecosystem services the new strategic focus for its Ecological Research Program (ERP). Understanding that the protection and ...
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Ecosystem Services: Priority strategic focus for U.S. EPA’s Ecological Research Program |
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U.S. EPA’s Office of Research and Development has made ecosystem services the new strategic focus for its Ecological Research Program (ERP). Understanding that the protection and ...
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Ecosystem and decomposer effects on litter dynamics along an old field to old-growth forest successional gradient |
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Identifying the biotic (e.g. decomposers, vegetation) and abiotic (e.g. temperature, moisture) mechanisms controlling litter decomposition is key to understanding ecosystem functio...
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Ecotoxicogenomics Short Course - Proteomics |
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Presentation at the 5th SETAC World Congress, Sydney, Australia, August 3-7, 2008....
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Effect Of Organic Substrate Composition On Microbial Community Structure Of Pilot-Scale Biochemical Reactors Treating Mining Influenced Water - (Presentation) |
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Mining-influenced water (MIW) is acidic, metal rich water formed when sulfide minerals react with oxygen and water. There are various options for the treatment of MIW; however, pa...
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Effect of Natural Organic Matter on the Reduction of Nitroaromatics by Fe(II) Species |
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Although natural organic matter is a necessary electron source for the microbial mediated development of redox zones in nature, uncertainty still exists regarding its role(s) in th...
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Effect of a peri-juvenile exposure to Triclosan on serum androgens and thyroid hormone in the male Wistar rat |
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Triclosan (5-chloro-2-(2,4-dichlorophenoxy)phenol) is a potent antibacterial and antifungal compound that is widely used in personal care products. Studies testing triclosan expos...
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Effect of acrolein (ACR) exposure with or without diesel exhaust particles (DEP) on allergic lung disease in ovalbumin (OVA)-sensitized mice. |
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Acrolein (ACR), a highly reactive irritant gas, is a toxic byproduct of gasoline and diesel combustion. To investigate whether ACR exposure with or without DEPs affected the initia...
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Effective Best Management Practices for Nitrogen Removal in Aquatic Ecosystems |
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Elevated nitrate levels in streams and groundwater are detrimental to human and ecosystem health. The Ground Water and Ecosystems Restoration Division (GWERD) of the USEPA investi...
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Effects of Hypoxia on Animal Burrow Constraction and Consequent Effects on Sediment Redox Profiles (SETAC08) |
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We investigated the effects of mild hypoxia on the burrowing behavior of three marine species (the hard clam Mercenaria mercenaria, the polychaete worm Nereis virens, and the amphi...
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Effects of Low Dissolved Oxygen on Organisms Used in Freshwater Sediment Toxicity Tests |
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This manuscript describes the results of tests to determine the tolerance of three benthic organisms to reduced dissolved oxygen (DO). These three organisms are those recommended b...
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Effects of atrazine (ATR), deisopropylatrazine (DIA), Diaminochlorotriazine (DACT) on the hypothalamic-pituitary-adrenal (HPA) axis in female rats |
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We previously reported that a single dose of the herbicide ATR stimulated the HPA axis in the male rat while equimolar doses of its primary metabolite, DACT, had a minimal effect. ...
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Effects of brominated flame retardants on calcium buffering mechanisms in rat brain in vitro. |
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Polybrominated diphenyl ethers (PBDEs; used as additive flame-retardants) have been detected in human blood, adipose tissue, and breast milk. Developmental and long-term exposures ...
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Effects of hypoxia on the response of fish to estrogen exposure |
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Natural and synthetic estrogens are common contaminants in surface waters and have the potential to affect reproduction in fish. Estrogens are likely to co-occur with low dissolved...
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Efficient Syntheses of Organics and Nanomaterials Using Microwaves |
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A brief account of reactions involving microwave (MW) exposure of neat reactants or catalyzed by mineral support surfaces, such as alumina, silica, clay, or their ‘doped’ versions,...
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Emergency Response and Protection Water Treatment Technologies |
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The Expeditionary Unit Water Purifier (EUWP) is supported
and deployed by NFESC, the TARDEC, and the USBR. The
EUWP was deployed to Biloxi, MS after Hurricane Katrina to
supply ...
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Emerging Contaminants in US Drinking Water: Do you know where your water's been? |
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The drinking water and wastewater cycles are integrally linked. Chemicals that are present in household wastewater may be sufficiently mobile and persistent to survive on-site or ...
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Emerging Contaminants in Water: A Perspective from the United States |
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Workshop presentation on emerging contaminants in water....
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Emerging Contaminants in the Drinking Water Cycle |
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In the past decade, the scientific community and general public have become increasingly aware of the potential for the presence of unregulated, and generally unmonitored contamina...
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Emerging Contaminants in the Drinking Water Cycle - MCEARD |
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In the past decade, the scientific community and general public have become increasingly aware of the potential for the presence of unregulated, and generally unmonitored contamina...
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Emerging Disinfection By-Products and Other Emerging Environmental Contaminants: What's New |
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Drinking water disinfection by-products (DBPs) have been associated with adverse human health effects, including bladder cancer, early term miscarriage, and birth defects. While i...
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Emerging Issues in Genotoxicity and Carcinogenicity with Implications for Structure Activity Analyses |
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In silico systems for the prediction of the ability of chemicals to induce carcinogenicity in rodents have generally relied on knowledge of the structure and physical-chemical feat...
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Emergy and Its Importance |
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Emergy is an important quantity needed for public policy analysis that is based on a complex methodology. The intent of this Environmental Research Brief is to define emergy and it...
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Encouraging stormwater management using a reverse auction: potential to restore stream ecosystems |
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Stormwater runoff is the primary mechanism by which urbanizing landscapes disrupt natural, stream ecosystems. Source control management has been demonstrated as an effective and c...
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Encouraging the use of wetlands in water quality trading programs |
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The interest in water quality trading (WQT) has grown in recent years because of its potential to meet nutrient reduction goals at lower costs. However, one problem identified by ...
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Energy efficient recovery and dehydration of ethanol from fermentation broths by Membrane Assisted Vapor Stripping technology |
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Distillation combined with molecular sieve dehydration is the current state of the art for fuel grade ethanol production from fermentation broths. To improve the sustainability of...
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Environmental Contaminants That Degrade in the Environment: Do They Really Disappear? |
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Slide presentation for the American Society for Mass Spectrometry 2008 meeting in Denver, CO....
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Environmental Decision Support with Consistent Metrics |
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One of the most effective ways to pursue environmental progress is through the use of consistent metrics within a decision making framework. The US Environmental Protection Agency...
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Environmental Flow Modeling Challenges for Rapidly Urbanizing Watersheds |
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It is a challenge for land use planners and water resource managers to balance water needs that support urban growth and economic development of a growing population and yet mainta...
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Environmental Health and Aging: Activity, Exposure and Biological Models to Improve Risk Assessment and Health Promotion |
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The US Environmental Protection Agency (EPA) and other public health agencies are concerned that the environmental health of America’s growing population of older adults has not be...
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Environmental Impact of Atmospheric NH 3 Emissions Under Present and Future Conditions in the Eastern United States |
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Recent regulations require large-scale emission reductions of NOx and SO2 in the eastern United States. These emission changes will alter the partitioning of...
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Environmental Indicators for the Coastal Region of North American Great Lakes: Introduction and Prospectus |
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Environmental indicators are benchmarks for the current conditions of the Great Lakes coastal region and provide measurable endpoints to assess the success of future management, co...
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Environmental Pollution and Health |
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Enormous progress has been made in identifying chemicals in the environment that adversely affect human health. The environment is cleaner, and, partly as a result, people are livi...
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Environmental Technology Verification: Biological Inactivation Efficiency by HVAC In-Duct Ultraviolet Light Systems--American Ultraviolet Corporation, DC24-6-120 [EPA600etv08005] |
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The Air Pollution Control Technology Verification Center (APCT Center) is operated by RTI International (RTI), in cooperation with EPA's National Risk Management Research Laborator...
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Epistasis-list.org: A Curated Database of Gene-Gene and Gene-Environment Interactions in Human Epidemiology |
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The field of human genetics has experienced a paradigm shift in that common diseases are now thought to be due to the complex interactions among numerous genetic and environmental ...
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Estimating aquatic hazards posed by prescription pharmaceutical residues from municipal wastewater |
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Risks posed by pharmaceuticals in the environment are hard to estimate due to limited monitoring capacity and difficulty interpreting monitoring results. In order to partially addr...
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Estimating the Impact of the 2004 Alaskan Forest Fires on Episodic Particulate Matter Pollution over the Eastern United States through Assimilation of Satellite Derived Aerosol Optical Depths in a Regional Air Quality Model |
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During the summer of 2004, extensive wildfires burned in Alaska and western Canada; the fires were the largest on record for Alaska. Smoke from these fires was observed over the co...
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Estimation of Carcinogenicity using Hierarchical Clustering and Nearest Neighbor Methodologies |
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Previously a hierarchical clustering (HC) approach and a nearest neighbor (NN) approach were developed to model acute aquatic toxicity end points. These approaches were developed ...
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Estimation of Henry's Law Constant for a Diverse Set of Organic Compounds from Molecular Structure |
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The SPARC (SPARC Performs Automated Reasoning in Chemistry) vapor pressure and activity coefficient models were coupled to estimate Henry’s Law Constant (HLC) in water and in hexad...
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Estuarine habitat utilization by birds in Yaquina Estuary, Oregon |
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A wide variety of bird species are highly dependent on intertidal wetland habitats. Because of this dependency, birds are viewed as important indicators of wetland structure and f...
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Estuarine intertidal sediment temperature variability in Zoster marina and Z. japonica habitats in Yaquina Bay, Oregon |
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Physical characterization of intertidal estuarine plant habitats over time may reveal distribution-limiting thresholds. Temperature data from loggers embedded in sediment in trans...
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Ethanol and Lead Scavengers in U.S. Gasolines |
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Powerpoint presentation on ethanol and lead scavengers in gasoline....
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Evaluating Regional-Scale Air Quality Models |
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Numerical air quality models are being used to understand the complex interplay among emission loading meteorology, and atmospheric chemistry leading to the formation and accumulat...
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Evaluation of Biomass Gasification to Produce Reburning Fuel for Coal-Fired Boilers |
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Gasification and reburning testing with biomass and other wastes is of interest to both the U.S. EPA and the Italian Ministry of the Environment & Territory. Gasification systems t...
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Evaluation of Commercial Cell Preparations as Sources of Calibration Standards for Real-Time qPCR Analysis of Enterococci in Recreational Waters |
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In response to the Beach Act, the U.S. EPA has developed a quantitative PCR (qPCR) method for enterococci that meets requirements for rapid, risk-based water quality assessments of...
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Evaluation of Two PCR-Based Swine-Specific Fecal Source Tracking Assays (Poster) |
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Several PCR-based methods have been proposed to identify swine fecal pollution in environmental waters. However, the specificity and distribution of these targets have not been ade...
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Evaluation of a Microarray for Genotyping Noroviruses |
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Noroviruses that infect humans are divided into three genogroups based upon their sequence diversity. Of these, genogroups I and II have been identified as leading causes of water...
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Evaluation of a real-time quantitative PCR method with propidium monazide treatment for analyses of viable fecal indicator bacteria in wastewater samples |
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The U.S. EPA is currently evaluating rapid, real-time quantitative PCR (qPCR) methods for determining recreational water quality based on measurements of fecal indicator bacteria D...
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Evaluation of a weighted test in the analysis of ordinal gait scores in an additivity model for five OP pesticides. |
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Appropriate statistical analyses are critical for evaluating interactions of mixtures with a common mode of action, as is often the case for cumulative risk assessments. Our objec...
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Evaluation of an index of biotic integrity approach to assess fish assemblage condition in Western USA streams and rivers at varying spatial scales |
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Consistent assessments of biological condition are needed across multiple ecoregions to provide a greater understanding of the spatial extent of environmental degradation. However,...
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Evaluation of an intensity error-model for Affymetrix GeneChips using a wholly-defined, control dataset |
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abstract for conference...
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Evaluation of the Impact of Chlorine on Mercury Oxidation in a Pilot-Scale Coal Combustion--The Effect of Coal Blending |
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Coal-fired power plants are a major source of mercury (Hg) released into the environment and the utility industry is currently investigating options to reduce Hg emissions. The EPA...
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Expeditious oxidation of alcohols to carbonyl compounds using iron(III) nitrate |
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An efficient and solvent-free protocol for the oxidation of alcohols to corresponding carbonyl compounds using iron (III) nitrate nonahydrate has been developed....
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Exploration of the Chemical Space of Public Genomic Databases |
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Exploration of the Chemical Space of Public Genomic Databases...
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Exposure Considerations for Chemical Prioritization and Toxicity Testing |
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Globally there is a need to characterize potential risk to human health and the environment that arises from the manufacture and use of tens of thousands of chemicals. Currently, ...
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Exposure Science and Its Applications for Effective Environmental Management |
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Exposure is the link between environmental pollution and human/ecosystem health. Exposure science entails understanding the scientific processes that affect source emissions, trans...
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Exposure to Phthalate Emitted from Vinyl Flooring and Sorbed to Interior Surfaces, Dust, Airborne Particles and Human Skin |
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There is an urgent need to characterize potential risk to human health and the environment that arises from the manufacture and use of tens of thousands of chemicals. Computationa...
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Extending the Diffuse Layer Model of Surface Acidity Constant Behavior: II. Estimation of Intrinsic Acidity and Electrolyte Ion Site Binding Constants |
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The two-pK metal oxide surface acidity constant model relies on generic mass action expressions of the form: Ka = [>SOHx-1x-2]aH+EXP(-ΔGexcess/RT)/[>SOHxX-l] where x equals 1 or 2....
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Extent of Sorption and Biodegradability of Perfluorooctanoic Acid (PFOA) and Perfluorooctanesulfonic Acid (PFOS) in Aquifer Sediment |
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Fluoropolymers such as Perfluorooctanoic Acid (PFOA) and Perfluorooctanesulfonic acid (PFOS) were used provide non-stick surfaces on cookware and waterproof, breathable clothing. ...
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FACTORS INFLUENCEING NITROGEN-CHLOROPHYLL RELATIONSHIPS FOR THE ESTUARIES ON THE U.S. ATLANTIC AND GULF OF MEXICO COASTS |
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a poster presentation at a multi-organizational scienitific conference...
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FECAL SOURCE TRACKING BY ANTIBIOTIC RESISTANCE ANALYSIS ON A RURAL WATERSHED |
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The Turkey Creek watershed located in northwestern Oklahoma, sustains approximately 40000 head of livestock. In addition, the stream receives partially-treated municipal waste from...
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FESTERING FOOD: CHYTRIDIOMYCETE PATHOGEN REDUCES QUALITY OF DAPHNIA HOST AS A FOOD RESOURCE |
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When parasitic infections are severe or highly prevalent among prey, a significant component of the predator’s diet may consist of parasitized hosts. However, despite the ubiquity...
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FIELD AND LABORATORY PERFORMANCE CHARACTERISTICS OF A NEW SAMPLING PROTOCOL FOR RIVERINE MACROINVERTEBRATE ASSEMBLAGES |
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Measurement and estimation of performance characteristics (i.e., precision, bias, performance range, interferences and sensitivity) are often neglected in the development and use o...
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FIELD EVALUATION OF ARSENIC TRANSPORT: SPECIATION IN SEDIMENT MATERIAL |
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Fort Devens was established in 1917 as Camp Devens, a temporary training camp for soldiers from the New England area for WWI. Throughout its history, Fort Devens served as a train...
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FIELD STUDY OF ARSENIC REMOVAL FROM GROUNDWATER BY ZEROVALENT IRON |
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Contamination of ground-water resources by arsenic is a widespread environmental problem; consequently, there is a need for developments and improvements of remedial technologies t...
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FOCUSING ON CHILDREN’S INHALATION DOSIMETRY AND HEALTH EFFECTS FOR RISK ASSESSMENT: AN INTRODUCTION |
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Substantial effort has been invested in improving children’s health risk assessment in recent years. However, the body of scientific evidence in support of children’s health asses...
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FORECASTS AND SENSITIVITY OF PCB BIOACCUMULATION IN FISH OF LAKE HARTWELL, SOUTH CAROLINA, USA |
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The EPA aquatic ecosystem model AQUATOX was applied to the Twelvemile Creek arm of Lake Hartwell, which received 400,000 lbs of PCBs from the Sangamo-Weston Superfund Site near Cle...
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FRom Pickle Jars to Ecosystem Services: Who Cares About Water Fleas Anyway? |
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We’ve made tremendous progress in protecting the environment since Ohio’s Cuyahoga River burned in 1969 – the air, water and land of this country are cleaner due in major part to t...
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FULL-GENOME ANALYSIS OF ALTERNATIVE SPLICING IN MOUSE LIVER AFTER HEPATOTOXICANT EXPOSURE |
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Alternative splicing plays a role in determining gene function and protein diversity. We have employed whole genome exon profiling using Affymetrix Mouse Exon 1.0 ST arrays to unde...
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Factors Influencing Ferrihydrite Crystallinity In Natural And Synthetic Systems |
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Recent investigations of the structure of the mineral ferrihydrite indicate that disparities in the number of peaks observed in powder x-ray diffraction patterns can be attributed ...
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Fate of High Priority Pesticides During Drinking Water Treatment |
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The fate of organophosphorus (OP) pesticides in the presence of chlorinated oxidants was investigated under drinking water treatment conditions. In the presence of aqueous chlorine...
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Feasibility of Community Food Item Collection for the National Children's Study |
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The National Children’s Study proposes to investigate the role of contaminants on health outcomes in pregnant women and children. A specific area of concern is contaminant exposure...
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Fecal Indicator Bacteria and Environmental Observations: Validation of Virtual Beach |
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Contamination of recreational waters by fecal material is often assessed using indicator bacteria such as enterococci. Enumeration based on culturing methods can take up to 48 hour...
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Field Evaluation Of Arsenic Speciation In Sediments At The Ground Water/Surface Water Interface |
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The speciation and mineralogy of sediments contaminated with arsenic at the ground water/surface water interface of the Ft. Devens Super Fund Site in Ft. Devens, MA were determined...
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Field Evaluation Of Arsenic Transport Across The Ground Water/Surface Water Interface: Speciation In Sediment Material |
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The solubility and mobility of arsenic in ground water are influenced by a variety of processes in the northeastern US subjective to geogenic and anthropogenic sources. This prese...
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Field Evaluation Of Arsenic Transport Across The Ground-Water/Surface Water Interface: Ground-Water Discharge And Iron Oxide Precipitation |
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A field investigation was conducted to examine the distribution of arsenic in ground water, surface water, and sediments at a Superfund Site in the northeastern United States (see ...
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Field Experience with Chlorine Dioxide Fumigation of a Hospital: Timeline and Lessons Learned |
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Chlorine dioxide (Cl02) fumigation technology was developed and successfully used to remediate four large buildings contaminated with anthrax spores from 2001 through 2004. As a fi...
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Final Project Report for Investigation of the Influence of Temporal Variation on Active Soil Gas/Vapor Sampling |
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Soil gas data are widely used in site investigation and remediation projects to delineate volatile organic compound (VOC) vapor plumes, as a screening tool to refine soil and groun...
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Fisher Information, Entropy, and the Second and Third Laws of Thermodynamics |
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We propose Fisher Information as a new calculable thermodynamic property that can be shown to follow the Second and the Third Laws of Thermodynamics. Fisher Information is, however...
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Fishing for Novel Approaches to Ecosystem Service Forecasts |
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The ecosystem service concept provides a powerful framework for conserving species and the environments they depend upon. Describing current distributions of ecosystem services an...
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Flux-Based Site Management |
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Managing DNAPL contaminated sites continues to be among the most pressing environmental problems currently faced. In particular, the benefits of partial DNAPL mass depletion due t...
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Formation Kinetics of Aqueous Suspensions of Fullerenes:Meeting in New Orleans. |
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Stable colloidal suspension of C60 is commonly achieved through various solvent exchange techniques. Nevertheless, the additives such as tetrahydrofuran may be retained in the C60...
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Formation and Occurrence of Disinfection By-Products |
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Disinfection by-products (DBPs) are formed when disinfectants such as chlorine, ozone, chlorine dioxide, or chloramines react with naturally occurring organic matter, anthropogenic...
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Formation of Emerging and High Molecular Weight DBPs from NOM |
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Workshop presentation on formation of emerging disinfection by-products reacting with natural organic matter....
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Formation of Secondary Organic Aerosol from Irradiated a-Pinene/Tolueme/NOx Mixtures and the Effect of Isoprene and Sulfur Dioxide |
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Secondary organic aerosol (SOA) was generated by irradiating a series of a-pinene/toluene/NOx mixtures in the absence and presence of isoprene or sulfur dioxide. The purpose of th...
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Four Possible Steps to Reduce Greenhouse Gas Emissions in Ada, Oklahoma |
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An overview of federal, state, and city initiatives on climate change are presented. Specific steps for the City of Ada, Oklahoma, are presented. This is an abstract of a propose...
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Framework for Optimizing the Evaluation of Data From Contaminated Soil in Sweden |
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The Swedish guidelines for the evaluation of data for the purpose of a risk assessment at contaminated sites are of a qualitative character, as opposed to the USEPA’s Data Quality ...
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Framework for Placement of BMPs in Urban Watersheds (2008) |
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The U.S. Environmental Protection Agency’s Urban Watershed Management Branch is responsible for developing and demonstrating methods to manage the risk to public health, property a...
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Frank and Opportunistic Pathogen Exposure Risks from Distribution System Biofilms |
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To be presented at Columbia University, New York, NY, November 9, 2007...
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From source-to-tap; Understanding the ecology of environmental pathogens for sustainable urban water use |
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Presentation given at The Water Cycle ISME, Cairns, Australia, August 20, 2008...
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Functionally charged nanosize particles differentially activate BV2 microglia. |
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The effect of particle surface charge on the biological activation of immortalized mouse microglia (BV2) was examined. Nanosize (860-950 nm) spherical polystyrene microparticles (S...
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Fusing Observations and Model Results for Creation of Enhanced Ozone Spatial Fields: Comparison of Three Techniques |
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This paper presents three simple techniques for fusing observations and numerical model predictions. The techniques rely on model/observation bias being considered either as error...
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GENE EXPRESSION PROFILING OF NORMAL HUMAN BRONCHIAL EPITHELIAL CELLS EXPOSED TO TRIVALENT ARSENICALS AND DIMETHYLTHIOARSINIC ACID |
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Lung is a major target for arsenic carcinogenesis in humans. However, the carcinogenic mode of action of arsenicals is unknown. We investigated, in human bronchial epithelial (BEAS...
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GENE EXPRESSION PROFILING OF XENOBIOTIC METABOLIZING ENZYMES (XMES) THROUGH THE LIFE STAGES OF THE MALE C57BL/6 MOUSE |
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In the presence of foreign compounds, metabolic homeostasis of the organism is maintained by the liver's ability to detoxify and eliminate these xenobiotics. This is accomplished, ...
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GEOCHEMICAL FACTORS GOVERNING METHYL MERCURY PRODUCTION IN MERCURY CONTAMINATED SEDIMENTS |
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Bench scale experiments were conducted to improve our understanding of aquatic mercury transformation processes (biotic and abiotic), specifically those factors which govern the pr...
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Gasoline Composition in 2008 |
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Gasoline composition in the U.S is determined by factors related to crude oil source, refinery capacity, geography and regulatory factors. Major regulation derived from the Clean ...
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Gender and Species-Mediated Differences in the In Vitro Metabolism of Triadimefon by Rodent Hepatic Microsomes |
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Understanding how metabolism kinetics differ between genders and species is important in developing informative pharmacokinetic models and accurately assessing risk. Metabolism of...
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Gene expression, proteomics and microarrays and their respective informatic approaches to address ecotoxicological issues (Gene expression, proteomics and microarrays) |
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Presentation at the 5th SETAC World Congress, Sydney, Australia, August 3-7, 2008...
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Generic Verification Protocol for Determination of Emissions from Cleaner Outdoor Wood-Fired Hydronic Heaters |
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This protocol describes the Environmental Technology Verification Program's considerations and requirements for verification of emissions reduction provided by cleaner outdoor wood...
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Genetic characterization of the burrowing shrimp (Neotrypaea californiensis) in Washington and Oregon estuaries |
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The Ghost shrimp, (Neotrypaea californiensis) are burrowers, which have a wide demographic distribution along the United States Pacific Coast. Our study used genetic analysis to e...
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Genomics in Regulatory Ecotoxicology: Applications and Challenges |
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This book is the result of a Pellston workshop. The primary goal of the workshop was to develop a conceptual framework concerning how genomic data could effectively impact differe...
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Geometry within Geographic Science (Spatial Analysis: GIS and Remote Sensing) |
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Presentation materials. If further information is requested, please refer to the bibliographic citation and contact the person listed under Principal Investigator....
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Geomorphic stream restoration as an approach for reducing nutrients in degraded urban watersheds |
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Elevated nitrate levels in streams and groundwater pose human and ecological threats. Stream restoration may improve the nutrient removal capacity of streams, yet few studies have...
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Green Infrastructure Research at NRMRL’s Urban Watershed Research Facility |
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USEPA’s National Risk Management Research Laboratory (NRMRL) examined several options for completing water quality research supporting the Clean Water Act and the Safe Drinking Wat...
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Green Roofs for Stormwater Management |
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This project evaluated green roofs as a stormwater management tool. Results indicate that the green roofs are capable of removing 40% of the annual rainfall volume from a roof thro...
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Green Synthetic Alternatives to Organic Compounds and Nanomaterials |
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A brief account of reactions involving microwave (MW) exposure of neat reactants or catalyzed by mineral support surfaces, such as alumina, silica, clay, or their ‘doped’ versions,...
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Green Synthetic Alternatives to Organic Compounds and Nanomaterials-May 2008 |
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A brief account of reactions involving microwave (MW) exposure of neat reactants or catalyzed by mineral support surfaces, such as alumina, silica, clay, or their ‘doped’ versions,...
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Green Synthetic Alternatives to Organic Molecules and Nanomaterials |
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A brief account of reactions involving microwave (MW) exposure of neat reactants or catalyzed by mineral support surfaces, such as alumina, silica, clay, or their ‘doped’ versions,...
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Greener Alternatives to Expedient Synthesis of Heterocycles and Nanomaterial |
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A brief account of reactions involving microwave (MW) exposure of neat reactants or catalyzed by mineral support surfaces, such as alumina, silica, clay, or their ‘doped’ versions,...
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Greener Biomimetic Approach to the Synthesis of Nanomaterials and Nanocomposite |
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A brief account of greener production of nanoparticles which reduces or eliminates the use and generation of hazardous substances is presented. The utility of vitamins B1 and B2, w...
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Greener Synthesis of Nanomaterials: Risk Reduction Strategies and Environmental Applications |
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A brief account of a greener preparation of nanoparticles which reduces or eliminates the use and generation of hazardous substances is presented. The utility of vitamins B1, B2, a...
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Greener Synthesis of Organics and Nanomaterials |
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A brief account of reactions involving microwave (MW) exposure of neat reactants or catalyzed by mineral support surfaces, such as alumina, silica, clay, or their ‘doped’ versions,...
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Greener Synthetic Alternatives to Heterocycles, Nanomaterials and Nanocomposites |
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Microwave (MW) expedited reaction of neat reactants or catalyzed by mineral support surfaces, such as alumina, silica, clay, or their ‘doped’ versions, for the rapid one-pot assemb...
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Greener Synthetic Alternatives to Organic Molecules and Nanomaterials |
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A brief account of reactions involving microwave (MW) exposure of neat reactants or catalyzed by mineral support surfaces, such as alumina, silica, clay, or their ‘doped’ versions,...
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Greener and Rapid Access to Bio-Active Heterocycles |
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A new kind of chemical revolution “GREEN CHEMISTRY” is brewing, 150 years after the first one transformed modern life with a host of conveniences. It protects the environment, not ...
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Groundwater Modeling of Mercury Pollution at a Former Mercury Cell Chlor Alkali Facility in Pavlodar City, Kazakhstan |
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In northern Kazakhstan, there is a serious case of mercury pollution near the city of Pavlodar from an old mercury cell chlor-alkali plant. The soil, sediment, and water is severe...
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Guidance for Evaluating in-vivo Fish Bioaccumulation Data |
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This paper provides guidance for evaluating the key aspects of study design and conduct that must be considered in judging the reliability and adequacy of reported laboratory data....
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HIGH PERMEABILITY MEMBRANES FOR THE DEHYDRATION OF LOW WATER CONTENT ETHANOL BY PERVAPORATION |
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Energy efficient dehydration of low water content ethanol is a challenge for the sustainable production of fuel-grade ethanol. Pervaporative membrane dehydration using a recently d...
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HIGHER ENVIRONMENTAL RELATIVE MOLDINESS INDEX (ERMISM) VALUES MEASURED IN DETROIT HOMES OF SEVERELY ASTHMATIC CHILDREN |
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Sieved vacuum bag dust from the homes of 143 children in Detroit was analyzed by mold specific quantitative PCR (MSQPCR) and the Environmental Relative Moldiness Index (ERMIsm) wa...
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HIGHLY SENSITIVE DETECTION OF GREEN CRAB (CARCINUS MAENAS AND CARCINUS ASTUARII) LARVAE IN MIXED PLANKTON SAMPLES USING POLYMERASE CHAIN REACTION AND RESTRICTION FRAGMENT LENGTH POLYMORPHISMS (PCR-RFLP) |
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The brachyuran crab genus Carcinus consists of two species, C. maenas and C. aestuarii, both of which have invaded multiple regins of the globe. C. maenas has proven a particularl...
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HISTORICAL EVALUATION AND ANALYSIS OF THE EMERGY TO MONEY RATIO FOR THE U.S. AND CHINA |
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Platform presentation at a scientific conference...
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HPLC-ICP/MS Analysis of Thyroid Hormone and Related Iodinated Compounds in Tissues and Media |
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Quantifying thyroid hormone (TH) and the synthetic precursors and metabolic products of TH is important for developing models of the hypothalamic-pituitary-thyroid (HPT) axis as we...
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HSPF Toolkit: a New Tool for Stormwater Management at the Watershed Scale |
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The Hydrological Simulation Program - FORTRAN (HSPF) is a comprehensive watershed model endorsed by US EPA for simulating point and nonpoint source pollutants. The model is used fo...
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HUMAN INFLUENCES ON WATER QUALITY IN GREAT LAKES COASTAL WETLANDS |
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This work supports MED research on aquatic stressors, and results have implications for 1) identifying and quantifying sources of nutrient loading from surrounding landscapes, as p...
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HYDROLOGIC MODEL CALIBRATION AND UNCERTAINTY IN SCENARIO ANALYSIS |
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A systematic analysis of model performance during simulations based on
observed land-cover/use change is used to quantify error associated with water-yield
simulation...
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HYDROLOGY AND LANDSCAPE CONNECTIVITY OF VERNAL POOLS |
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Vernal pools are shaped by hydrologic processes which influence many aspects of pool function. The hydrologic budget of a pool can be summarized by a water balance equation that re...
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Has the Performance of Regional-Scale Photochemical Modelling Systems Changed over the Past Decade? |
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This study analyzed summertime ozone concentrations that have been simulated by various regional-scale photochemical modelling systems over the Eastern U.S. as part of more than te...
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Hepatotoxicity of Chlorpyrifos in Zebrafish Liver Cells by NMR-based Metabolomics |
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For decades chlorpyrifos (CPS) has been one of the most widely used organophosphate insecticides for a variety of agricultural and public health applications. The extensive use of ...
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Heterogeneous Activation Of Peroxymonosulfate With Iron-Cobalt Bimetallic Nanocatalysts |
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Sulfate radical-based advanced oxidation technologies (SR-AOTs) are attracting considerable attention due to the high oxidizing ability of sulfate radicals (SRs) to degrade various...
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Homogeneous And Heterogeneous Activation Of Peroxymonosulfate With Iron-Based Catalysts |
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Polychlorinated biphenyls (PCBs) in the environment pose long-term risk to public health because of their persistent and toxic nature. This study investigates the degradation of P...
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How Are Changing Solar Ultraviolet Radiation and Climate Affecting Light-induced Chemical Processes in Aquatic Environments? |
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Changes in the ozone layer over the past three decades have resulted in increases in solar UV-B radiation (280-315 nm) that reach the surface of aquatic environments. These changes...
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Hybridization between invasive Spartina Densiflora (Poaceae) and native S. Foliosa in San Francisco Bay, California, USA |
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Rapid evolution in contemporary time can result when related species, brought together through human-aided introduction, hybridize. The evolutionary consequences of post introduct...
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Hydrology and Hyporheic Nitrogen Biogeochemistry in a Geomorphically Degraded Urban Stream |
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Few studies have investigated the relationship between hydrology and nitrogen biogeochemistry in hyporheic zones of degraded urban streams despite significant national efforts to r...
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Hydrology and Nitrogen Biogeochemistry in the Hyporheic Zone of a Geomorphically Degraded Urban Stream |
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Few studies have investigated the relationship between hydrology and nitrogen biogeochemistry in hyporheic zones of degraded urban streams despite significant national efforts to r...
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Hypoxia Alters Gene Expression in the Gonads of Zebrafish, Poster Presentation |
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The objectives of this study were to characterize gene expression responses to hypoxia in gonads of mature zebrafish (Danio rerio), and to determine how the duration of exposure af...
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IDENTIFICATION OF EARLY MOLECULAR EVENTS AFTER PEROXISOME PROLIFERATOR EXPOSURE IN THE RODENT LIVER |
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Peroxisome proliferators (PP) are a large class of structurally diverse chemicals that mediate their effects in the liver mainly through the PP-activated receptor α(PPARα). De...
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IDENTIFICATION OF INTERSPECIES CONCORDANCE OF MECHANISMS OF ARSENIC-INDUCED BLADDER CANCER |
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Exposure to arsenic causes cancer by inducing a variety of responses that affect the expression of genes associated with numerous biological pathways leading to altered cell growth...
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IDENTIFYING INDICATORS OF REACTIVITY FOR CHEMICAL REDUCTANTS IN ANOXIC AND ANAEROBIC SEDIMENTS |
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To develop reaction transport models describing the movement of redox-active organic contaminants through contaminated sediments and aquifers, it is imperative to know the identity...
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IGE IN ASTHMATIC HUMAN SERA IS REACTIVE AGAINST MOLD EXTRACTS |
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Molds have been associated with various health effects including asthma, but their role in induction of asthma is unclear. However, the presence of mold-specific IgE indicates thei...
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IMMUNE FUNCTION IN INTACT AND PPARΑ KNOCKOUT MICE EXPOSED TO PFOA |
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Perfluorooctanoic acid (PFOA), used in fluoropolymer production, is environmentally persistent, present in human and wildlife populations worldwide, and associated with health effe...
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IMPACT OF AN UPDATED CARBON BOND MECHANISM ON PREDICTIONS FROM THE CMAQ MODELING SYSTEM: PRELIMINARY ASSESSMENT |
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An updated and expanded Carbon Bond mechanism (CB05) has been incorporated into the Community Multiscale Air Quality modeling system to more accurately simulate wintertime, pristin...
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IMPACT OF SUBMERSIBLE PUMPS ON PB CONSTITUENTS IN RESIDENTIAL WELLS |
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Dissolved lead in 51 domestic wells screened from 18 m to 48 m in glacial tills and outwash deposits were examined, from archived samples collected during 2001-2004, in conjunction...
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IMPACT ON DISINFECTION AT PEAK FLOWS DURING BLENDING/PARTIAL BYPASSING OF SECONDARY TREATMENT |
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A U.S EPA study evaluated the impact on disinfection during peak flows when a portion of the flow to the wastewater treatment plant (WWTP) bypasses secondary treatment prior to dis...
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IMPACTS OF DISSOLVED ORGANIC MATTER VARIABILITY ON CORALS-ASSOCIATED MICROBIAL COMMUNITIES IN THE FLORIDA KEYS |
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Coral reefs in the Florida Keys have experienced a significant decrease in coral cover over the past few decades with most reefs currently exhibiting <10% overall coral cover. ...
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IMPEDIMENTS AND SOLUTIONS TO SUSTAINABLE, WATERSHED-SCALE URBAN STORMWATER MANAGEMENT: LESSONS FROM AUSTRALIA AND THE UNITED STATES |
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In urban and exurban areas, stormwater runoff is a primary stressor on surface waters (streams, wetlands, lakes, estuaries, and coastal waters). Conventional urban stormwater drai...
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IN VITRO EFFECTS OF ENVIRONMENTALLY RELEVANT POLYBROMINATED DIPHENYL ETHER (PBDE) CONGENERS ON CALCIUM BUFFERING MECHANISMS IN RAT BRAIN |
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Polybrominated diphenyl ethers (PBDEs) are widely used as additive flame-retardants and have been detected in human blood, adipose tissue, and breast milk. Developmental and long-t...
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IN VIVO DERMAL ABSORPTION OF PYRETHROID PESTICIDES IN THE RAT |
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The potential for exposure to pyrethroid pesticides has risen recently because of their increased agricultural and residential use. The objective of this study was to examine the ...
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INFLUENCE OF DIET ON THE PERFORMANCE OF BOVINE FECAL POLLUTION DETECTION METHODS AND MICROBIAL POPULATION STRUCTURE |
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ABSTRACT
Background and Aims. Waterborne diseases originating from bovine fecal material are a significant public health issue. Ensuring water quality requires the use of method...
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INHALED COMPLEX COMBUSTION EMISSIONS UPREGULATE TRANSCRIPTION AND ACTIVITY OF SYSTEMATIC MATRIX METALLOPROTEINASE-9 (MMP9): EVIDENCE IN MURINE AND HUMAN MODELS |
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Air pollution is associated with acute and chronic adverse human health effects related to atherosclerotic pathologies. MMP9 has a crucial role in the progression and ultimate deg...
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INHIBITION OF TYROSINE PHOSPHATASE ACTIVITY INITIATES RECEPTOR SIGNALING IN AIRWAY EPITHELIAL CELLS EXPOSED TO DIESEL EXHAUST PARTICLES |
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Exposure to particulate matter is associated with increased cardiopulmonary morbidity and mortality. Diesel exhaust particles (DEP) are a major component of PM in urban areas and m...
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INTEGRATED DISINFECTION BYPRODUCTS MIXTURES RESEARCH: COMPREHENSIVE CHARACTERIZATION OF WATER CONCENTRATES PREPARED FROM CHLORINATED AND OZONATED/POSTCHLORINATED DRINKING WATER |
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This article describes the disinfection byproduct (DBP) characterization portion of a series of experiments designed for comprehensive chemical and toxicological evaluation of two ...
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INTEGRATED SCIENCE ASSESSMENT (ISA) FOR SULFUR OXIDES – HEALTH CRITERIA (FInal Report) |
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EPA is announcing the release of the Integrated Science Assessment (ISA) for Sulfur Oxides – Health Criteria final assessment. This ISA represents a concise synthesis and ev...
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INTEGRATED SCIENCE ASSESSMENT FOR OXIDES OF NITROGEN – HEALTH CRITERIA (FINAL REPORT) |
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The Integrated Science Assessment (ISA) for Oxides of Nitrogen – Health Criteria document represents a concise synthesis and evaluation of the most policy-relevant science and will...
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INTEGRATION OF PATHOLOGY AND TOXICOLOGY IN RISK ASSESSMENT |
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In order to develop a scientifically defensible assessment of the risk for the development of cancer after long-term exposure to xenobiotics, regulatory agencies have adopted a uni...
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INTERCOMPARISON OF SCIAMACHY AND OMI TROPOSPHERIC NO2 COLUMNS: OBSERVING THE DIURNAL EVOLUTION OF CHEMISTRY AND EMISSIONS FROM SPACE |
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Concurrent (August 2006) satellite measurements of tropospheric NO2 columns from OMI aboard Aura (13:30 local overpass time) and SCIAMACHY aboard Envisat (10:00 overpas...
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INTERIM GUIDANCE FOR DEVELOPING GLOBAL POSITIONING SYSTEM DATA COLLECTION STANDARD OPERATING PROCEDURES AND QUALITY ASSURANCE PROJECT PLANS |
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The United States Environmental Protection Agency Geospatial Quality Council developed this document to harmonize the process of collecting, editing, and exporting spatial data of ...
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INTERIM REPORT, DEVELOP A SAMPLING STRATEGY: PREPARE TO IMPLEMENT A COHORT STUDY OF CHILDREN'S ENVIRONMENTAL HEALTH |
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Overview
The goal of the National Children's Study (NCS) is to collect information on environmental and
social factors in the lives of children, starting before birth...
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INTERPRETATION OF BENZENE URINARY BIOMARKER DATA FOR RISK ASSESSMENT: A CASE STUDY |
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Human biomonitoring is an effective tool in assessing exposure to hundreds of chemicals. Too often, however, biomarkers such as parent or metabolite concentrations in blood or uri...
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INTRODUCTION OF THE VITELLOGENIN GENE IN EARLY LIFE STAGE FATHEAD MINNOWS AS AN EFFECTIVE EXPOSURE INDICATOR FOR ESTROGENIC COMPOUNDS |
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Vitellogenin (Vg) gene expression in adult male fathead minnows (FHM) has previously been used successfully to detect exposures to estrogenic compounds in aquatic systems; however,...
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IODO-ACID DISINFECTION BY-PRODUCTS IN DRINKING WATER: DOES LC/ESI-MS/MS OFFER AN ADVANTAGE OVER GC/NCI-MS? |
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As part of a recent Nationwide Disinfection By-Product (DBP) Occurrence Study, iodo-acids were identified for the first time as DBPs in drinking water disinfected with chloramines....
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IRIS 2008 Agenda |
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IRIS 2008 Agenda: Literature Searches And Request For Information For New Starts
IRIS is an EPA database of human health effects that may result from exposure to chemical...
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IRIS HEALTH ASSESSMENT OF 2,2',4,4'-TETRABROMODIPHENYL ETHER (BDE-47) CASRN 5436-43-12,2',4,4',5-PENTABROMODIPHENYL ETHER (BDE-99) CASRN 60348-60-92,2',4,4',5,5'-HEXABROMODIPHENYL ETHER (BDE-153) CASRN 68631-49-22,2',3,3',4,4',5,5',6,6'-DECABROMODIPHENYL ETHER (BDE-209) CASRN 1163-19-5 |
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Polybrominated diphenyl ethers (PBDEs) are used as flame retardants in furniture foam (pentaBDE), plastics for TV cabinets, consumer electronics, wire insulation, and backcoatings ...
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IRIS PROCESS (2008 UPDATE) |
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The Integrated Risk Information System (IRIS) is a U.S. Enviro...
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IRIS TOXICOLOGICAL REVIEW AND SUMMARY DOCUMENTS FOR 1,1,2,2-TETRACHLOROETHANE |
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EPA's assessment of the carcinogenic potential of 1,1,2,2-tetrachloroethane was entered into the IRIS database in 1987. The IRIS program is preparing an update of the IRIS assessme...
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IRIS TOXICOLOGICAL REVIEW OF 1,2,3-TRICHLOROPROPANE (EXTERNAL REVIEW DRAFT) |
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EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of 1,2,3-trichloropropane (TCP) that once finalized will app...
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IRIS TOXICOLOGICAL REVIEW OF ACRYLAMIDE (EXTERNAL REVIEW DRAFT) |
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EPA is conducting a peer review by EPA’s Science Advisory Board (SAB) of the scientific basis supporting the human health hazard and dose-response assessment of acrylamide that onc...
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IRIS TOXICOLOGICAL REVIEW OF BERYLLIUM (EXTERNAL REVIEW DRAFT) |
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EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of beryllium that will appear on the Integrated Risk Informa...
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IRIS TOXICOLOGICAL REVIEW OF CERIUM OXIDE AND CERIUM COMPOUNDS (EXTERNAL REVIEW DRAFT) |
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EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of cerium oxide and cerium compounds that will appear on the...
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IRIS TOXICOLOGICAL REVIEW OF CHLORDECONE (KEPONE) (EXTERNAL REVIEW DRAFT) |
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EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of chlordecone that will appear on the Integrated Risk Infor...
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IRIS TOXICOLOGICAL REVIEW OF TETRACHLOROETHYLENE (PERCHLOROETHYLENE) (EXTERNAL REVIEW DRAFT) |
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EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of tetrachloroethylene that will appear on the Integrated Ri...
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IRIS TOXICOLOGICAL REVIEW of CARBON TETRACHLORIDE (External Review Draft) |
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EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of carbon tetrachloride that will appear on the Integrated R...
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IRIS Toxicological Review of Decabromodiphenyl Ether (Final Report) |
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The purpose of this Toxicological Review is to provide scientific support and rationale for the hazard and dose-response assessment in IRIS pertaining to chronic exposure to dec...
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IRIS Toxicological Review of Ethylene Glycol mono-Butyl Ether (EGBE) (External Review Draft) |
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EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of ethylene glycol monobutyl ether that will appear on the I...
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IRIS Toxicological Review of Hexabromodiphenyl Ether (Final Report) |
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The purpose of this Toxicological Review is to provide scientific support and rationale for the hazard and dose-response assessment in IRIS pertaining to chronic exposure to 2,2...
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IRIS Toxicological Review of Pentabromodiphenyl Ether (Final Report) |
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The purpose of this Toxicological Review is to provide scientific support and rationale for the hazard and dose-response assessment in IRIS pertaining to chronic exposure to 2,2...
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IRIS Toxicological Review of Tetrabromodiphenyl Ether (Final Report) |
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The purpose of this Toxicological Review is to provide scientific support and rationale for the hazard and dose-response assessment in IRIS pertaining to chronic exposure to 2,2...
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ISEA 2007 Panel: Integration of Better Exposure Characterizations into Disaster Preparedness for Responders and the Public |
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An expert panel was convened in October 2007 at the International Society for Exposure Analysis (ISEA) Annual Meeting in Durham, NC, entitled “The Path Forward in Disaster Prepared...
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ISOFIT - A PROGRAM FOR FITTING SORPTION ISOTHERMS TO EXPERIMENTAL DATA |
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Isotherm expressions are important for describing the partitioning of contaminants in environmental systems. ISOFIT (ISOtherm FItting Tool) is a software program that fits isotherm...
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IT’S GOOD TO BE BIG—PHAEOCYSTIS ANTARCTICA COLONY SIZE UNDER THE INFLUENCE OF ZOOPLANKTON GRAZERS |
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The haptophyte Phaeocystis antarctica forms extremely dense accumulations in the Ross Sea, Antarctica, and accounts for over 60% of the seasonal primary production. Similar to the ...
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Identification of Active Bacterial Communities in Drinking Water Using 16S rRNA-Based Sequence Analyses |
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DNA-based methods have considerably increased our understanding of the bacterial diversity of water distribution systems (WDS). However, as DNA may persist after cell death, the us...
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Identifying Sources of Fecal Contamination in Streams Associated with Chicken Farms |
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Poultry is responsible for 44% of the total feces production in the U.S., followed by cattle and swine. The large U.S. production of feces poses a contamination risk for affected ...
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Immunotoxicity -- The Risk is Real |
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Several papers published over the last year represent significant progress in closing the gap between rodent immunotoxicity data and human risk and indicate that, at least for the ...
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Impact of Mountaintop Mining/Valley Fill on the Stable Carbon Isotopic Composition and Concentration of Dissolved Organic Carbon and Dissolved Inorganic Carbon in Headwater Streams |
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Headwater streams are the dominant land-water interface across much of the landscape and provide many important ecological services. Cycling and transport of various carbon fractio...
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Impact of Urbanization on Water Quantity and Quality: The Need for an Integrative Watershed Modeling Approach |
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Economic development through natural resource extraction is the primary driver of land use change. Land use change generally occurs as a result of urban development (residential, c...
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Impact of a classic paper by H. Ronald Pulliam: An overview of the first twenty years (1988-2007) |
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In 1988, H. Ronald Pulliam published the classic paper, “Sources, Sinks, and Population Regulation.” The message of this paper was that population dynamics can change across heter...
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Impact of meteorology, traffic characteristics, and distance from roadway on roadside concentrations of ultrafine particulate matter |
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Traffic-laden roadways are major contributors to poor air quality in developed areas, elevating pollutants such as particulate matter (PM) and ozone. Among the numerous air pollut...
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Implementation of retrofit BMPs in a suburban watershed via economic incentives |
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Urban stormwater is typically conveyed to centralized infrastructure, and there is great potential for reducing stormwater runoff quantity through decentralization. In this case we...
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Improved Leach Testing for Evaluating Fate of Mercury and Other Metals from Management of Coal Combustion Residues |
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Coal-fired power plants, the largest domestic source of atmospheric mercury emissions in the U.S., are also a major emission source of nitrogen oxides (NOx), sulfur dioxide (S02), ...
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Improving EPA Chemical Risk Assessment Information Availability: Using DSSTox Database Technology and IRIS Data in Computational Toxicology |
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Abstract for a poster to show the mission of the EPA's Distributed Structure-Searchable Toxicity (DSSTox) Database project is to improve structure-activity and predictive toxicity ...
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Improving Lab Sample Management - POS/MCEARD |
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"Scientists face increasing challenges in managing their laboratory samples, including long-term storage of legacy samples, tracking multiple aliquots of samples for many experimen...
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Improving the Scientific Foundation for Mixtures Joint Toxicity and Risk Assessment: Contributions from the SOT Mixtures Project |
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This paper summarizes the activities of the SOT (Society of Toxicology) Mixtures Program and the SOT Task Force. As such it provides the history leading to the formation of the SO...
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In Situ Biodegradation of MTBE and TBA |
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Ground water at most UST spills sites in Kansas contains both MTBE and benzene, and both contaminants must be effectively treated to close the sites. Soil vacuum extraction, and a...
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In vivo mutagenicity of conazole fungicides correlates with tumorigenicity |
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Triadimefon, propiconazole, and myclobutanil are conazoles, an important class of agricultural and therapeutic fungicides. Triadimefon and propiconazole are mouse liver tumorigens,...
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In-situ exposure of fish for biomarker experimentation at Department of Water Resources (DWR) real-time monitoring sites |
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For decades, the field of aquatic toxicology has assessed the health of water bodies using, primarily, laboratory based static-renewal toxicity tests. In recent years, there has be...
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In-vitro Cell Culture and Real-time Reverse Transcriptase PCR-based Assays to Detect Infective Toxoplas gondii Oocysts |
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Toxoplasma gondii is an obligate intracellular, apicomplexan parasite that infects humans. It is ubiquitous in nature and seroprevalence in the United States and in Europe ranges f...
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Incorporation of Modeling in Assessment of Diving Plumes |
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Powerpoint presentation on modeling in assessment of diving plumes....
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Increasing Confidence In Treatment Performance Assessment Using Geostatistical Methods |
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It is well established that the presence of dense non-aqueous phase liquids (DNAPLs) such as trichloroethylene (TCE) in aquifer systems represents a very long-term source of ground...
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Influence of Activity on Transfer of Pesticides from Treated Formica ® in Foods |
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The children’s dietary intake model (CDIM) has been developed to predict total dietary intake of a child incorporating excess exposures due to handling of food prior to consumption...
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Influence of Land Use and Watershed Characteristics on Protozoa Contamination in a Potential Drinking Water Resources Reservoir |
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Relative changes in the microbial quality of Lake Texoma, on the border of Texas and Oklahoma, were investigated by monitoring protozoan pathogens, fecal indicators, and factors in...
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Insight into molecular mechanisms of ultrafine carbon particle induced cardiovascular impairments in spontaneously hypertensive rats. |
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Rationale: Exposure to ambient particulate matter is a risk factor for cardiopulmonary disease as identified in several epidemiological studies. Radio telemetric analysis detected ...
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Integrated Disinfection By-Products Mixtures Research: Results from the Four Lab Study |
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This study involves collaboration of four national laboratories/centers of the U.S. Environmental Protection Agency (EPA), as well as scientists from universities and water utiliti...
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Integrated Monitoring, Modeling and Mapping for Managing and Valuing Bundled Services in the US – Ecosystem Services Research and Development at the EPA |
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The Ecological Research Program (ERP) of the EPA Office of Research and Development has the vision of a comprehensive theory and practice for characterizing, quantifying, and valui...
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Integrating Demographic, Clinical,and Environmental Exposure Information to Identify Genomic Biomarkers Associated With Subtypes of Childhood Asthma |
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Childhood asthma is a multifactorial disease with a disturbingly high incidence in urbanized areas. The pathogenesis of asthma is poorly understood due to the complex relationship ...
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Integration of DNA barcoding approaches into aquatic bioassessments |
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The Clean Water Act directs states to protect water resources by developing criteria based in part on biological assessments of natural aquatic ecosystems. Current protocols can be...
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Integration of Flux-Based Methods and Triad Principles for DNAPL Site Management, Part II: Review of Flux Measurement Methods |
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Managing dense nonaqueous phase liquid (DNAPL) contaminated sites continues to be among the most pressing environmental problems currently faced. One approach that has recently bee...
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Integration of genomic endpoints into toxicity identification evaluations |
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Toxicity identification and evaluations (TIEs) use physical/chemical manipulation of a sample to isolate or change the potency of different groups of toxicants potentially present ...
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Interaction between land use and climate variability amplifies stream nitrate export |
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We investigated regional effects of urban land use change on nitrate concentrations in approximately 1,000 small streams in Maryland, U.S.A. during record drought and wet years in ...
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Interactions of Changing Solar Ultraviolet Radiation and Climate with Light Induced Chemical Reactions in Aquatic Environments |
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Changes in the ozone layer over the past two decades have resulted in increases in solar ultraviolet radiation that reach the surface of North American aquatic environments. Concur...
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Interferon Gamma as a Biomarker of Exposure to Enteric Viruses |
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Interferon gamma (IFN-γ) was selected as a biomarker for viral exposure. Twelve-week-old BALB/c mice were intraperitoneally injected with Coxsackievirus B3 or B4 diluted in phospha...
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International use of risk assessment/risk management to direct waterborne pathogen research |
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Presentation to given at the Pathogens-In-Groundwater Research Consortium National Workshop, Delta Bow Valley, Calgary, Canada, September 4-5, 2008...
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Investigating Adaptive, Compensatory, and Toxic Responses of Fathead Minnow (Pimephales promelas) Exposed to 17α-ethynylestradiol using NMR-based Metabolite Profiling |
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Determining the impact(s) on fish and other aquatic organisms of exposure to endocrine disrupting compounds (EDCs) is critical for determining the risks that these chemicals pose. ...
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Investigation of In-situ Biogeochemical Reduction of Chlorinated Solvents in Groundwater by Reduced Iron Minerals |
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Biogeochemical transformation is a process in which chlorinated solvents are degraded abiotically by reactive minerals formed by, at least in part or indirectly from, anaerobic bio...
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Investigation of the Biotransformation of a DMA in Mouse Cecum Samples Using IC-ICP-MS and LC-ESI-MS/MS Detection |
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Recent arsenic metabolism studies have begun to indicate the presence of sulfur analogs of the more common arsenic oxides in biological systems. An emerging area of research is ho...
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Investigations of anticoagulant rodenticide exposure in wildlife in a national park in southern California: distribution, extent, and effects of exposure in multiple carnivores, surveys of human use, and exposure in small mammals and lagomorphs |
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Since 1996, we have been studying the ecology and conservation of mammalian carnivores, including bobcats, coyotes, and more recently mountain lions, at Santa Monica Mountains Nati...
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Ionic Stress to Invertebrates in Appalachian Headwater Streams |
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Poster presentation of the analysis and summary of available empirical datasets to develop empirical relationships and compare these results to toxicity testing data from various l...
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Iron homeostasis in the lung following asbestos exposure |
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Human exposure to asbestos can cause a wide variety of pulmonary diseases, including pneumoconiosis (i.e., asbestosis). This lung injury is mediated by oxidant generation which inc...
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Iron homeostatis and oxidative stress in idiopathic pulmonary alveolar proteinosis: a case-control study |
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ABSTRACT: BACKGROUND: Lung injury caused by both inhaled dusts and infectious agents depends on increased availability of iron and metal-catalyzed oxidative stress. Because inhaled...
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Kinetic Modeling of Polychlorinated Dibenzo-p-dioxin and Dibenzofuran Formation Based on Carbon Degradation Reactions |
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Combustion experiments in a laboratory-scale fixed bed reactor were performed to determine the role of temperature and time in PCDD/F formation allowing a global kinetic expression...
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Knowledge base for v-Embryo: Information Infrastructure for in silico modeling |
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Computers, imaging technologies, and the worldwide web have assumed an important role in augmenting traditional learning. Resources to disseminate multimedia information across pl...
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LACK OF ALTERATIONS IN THYROID HORMONES FOLLOWING EXPOSURE TO POLYBROMINATED DIPHENYL ETHER 47 DURING A PERIOD OF RAPID BRAIN DEVELOPMENT IN MICE |
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Polybrominated diphenyl ether 47 (PBDE-47) is one of a class of commonly used flame retardants that are accumulating in the environment, including human tissues. There are reports ...
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LANDSCAPE INDICATORS OF WATERSHED IMPAIRMENT - NUTRIENTS |
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Abstract for presentation...
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LANDSCAPE INFLUENCES ON LAKE CHEMISTY OF SMALL DIMICTIC LAKES IN THE HUMAN DOMINATED SOUTHERN WISCONSIN LANDSCAPE |
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Changes in landscape heterogeneity, historic landcover change, and human disturbance regimes are governed by complex interrelated landscape processes that modify lake water quality...
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LARGE SCALE DISASTER ANALYSIS AND MANAGEMENT: SYSTEM LEVEL STUDY ON AN INTEGRATED MODEL |
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The increasing intensity and scale of human activity across the globe leading to severe depletion and deterioration of the Earth's natural resources has meant that sustainability h...
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LEVELS OF SYNTHETIC MUSK COMPOUNDS IN MUNICIPAL WASTEWATER FOR ESTIMATING BIOTA EXPOSURE IN RECEIVING WATER |
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To test the ruggedness of a newly developed analytical method for synthetic musks, a 1-year monthly monitoring of synthetic musks in water and biota was conducted for Lake
M...
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LIGHT-INDUCED PROCESSES AFFECTING ENTEROCOCCI IN AQUATIC ENVIRONMENTS |
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Fecal indicator bacteria such as enterococci have been used to assess contamination of freshwater and marine environments by pathogenic microorganisms. Various past studies have s...
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LINKAGE BETWEEN PRODUCTION AND RESPIRATION ON THE LOUISIANA CONTINENTAL SHELF. |
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Abstract for presentation.
Original title, "PRIMARY PRODUCTION, BACTERIOPLANKTON PRODUCTION, AND COMMUNITY RESPIRATION IN STRATIFIED WATERS OF THE NORTHERN GULF OF MEXICO CONTINEN...
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LINKING SOLID PHASE SPECIATION OF PB SEQUESTERED TO BIRNESSITE TO ORAL PB BIOACCESSIBLITY: IMPLICATIONS FOR SOIL REMEDIATION |
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Lead (Pb) sorption onto oxide surfaces in soils may strongly influence the risk posed from incidental ingestion of lead-contaminated soils. In this study, Pb was sorbed to a model...
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LOW NOX, HIGH EFFICIENCY MULTISTAGED BURNER: GASEOUS FUEL RESULTS |
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The paper discusses the evaluation of a multistaged combustion burner design on a 0.6 MW package boiler simulator for in-furnace NOx control and high combustion efficiency. Both de...
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LUNG INJURY IS INDUCED BY INSOLUBLE AND TOTAL BUT NOT SOLUBLE PARTICULATE MATTER (PM) COLLECTED IN MEXICO CITY |
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Exposure to ambient air PM has been associated with adverse cardiopulmonary health effects; however, causative components have not been identified. The solubility of PM constituent...
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Laboratory Evaluations of the Enterococcus qPCR Method for Recreational Water Quality Testing: Method Performance and Sources of Uncertainty in Quantitative Measurements |
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The BEACH Act of 2000 directed the U.S. EPA to establish more expeditious methods for the detection of pathogen indicators in coastal waters, as well as new water quality criteria ...
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Landscape Thresholds and the Condition of Northeastern Estuaries |
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Anthropogenic impacts to northeastern estuaries have been well documented and many researchers have quantified the associations between broad scale human land uses in contributing ...
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Landscape-based Indicators |
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The report is based on data and experience gained through the GLNPO-funded Great Lakes Coastal Wetland Consortium (GLCWC) and the EPA-STAR funded Great Lakes Ecological Indicators ...
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Larval salamanders and channel geomorphology are indicators of hydrologic permanence in forested headwater streams |
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Regulatory agencies need rapid indicators of hydrologic permanence for jurisdictional determinations of headwater streams. Our study objective was to assess the utility of larval s...
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Lead Scavengers in Old Product Samples: An EPA Evaluation |
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Slide presentation presented at the 20th Annual Tanks Conference on lead scavengers in old product samples....
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Legionella - (re-) awakening to the amoeba-based pathogens of distribution system biofilms |
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Presentation to be given at the Environmental Research Laboratory, University of Arizona, Tucson, Arizona, July 24, 2008...
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Legionella - (re-)awakening to the Amoeba-based Pathogens of Distribution System Biofilm |
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Fecal pathogens have long been the focus of concern in the distribution of drinking waters. Yet today, with distribution system ‘failures’ accounting for the majority of waterborne...
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Lessons Learned - Modeling Cancer Data |
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The primary goal of modeling in this exercise is to derive a single point of departure (POD) for use in calculating a margin of exposure (MOE) estimate, and evaluate its uncertaint...
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Letter to the Editor: Response to comments from Drs. Grahame & Hidy on "Comparative Toxicity of Size-Fractionated Airborne Particulate Matter..." |
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This is a response to the comments of Drs. Grahame and Hidy on the above referenced article....
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Levels of brominated diphenylether, dibenzo-P-dioxin, and dibenzofuran in flue gases of a municipal waste combustor |
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Due to the extensive use of brominated flame retardants (BFRs), including brominated diphenylether (BDE) formulations, for various domestic and industrial applications, the presenc...
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Life Cycle Assessment of an Ionic LIquid versus Traditional Solvents and Their Applications |
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Ionic liquids (ILs) have been claimed as "greener" replacements to traditional solvents. HOwever, the environmental impacts of the life cycle phases including the making of ILs, th...
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Light-Induced Decomposition of Surface Litter from the Cerrado in Central Brazil |
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It is well-established that light-induced decomposition can accelerate the decomposition of the organic matter in aquatic environments. In this study, using the production of carbo...
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Linkage of exposure and effects using genomics, proteomics and metabolomics in small fish models (presentation) |
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This research project combines the use of whole organism endpoints, genomic, proteomic and metabolomic approaches, and computational modeling in a systems biology approach to 1) id...
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Linking Global and Regional Models to Simulate U.S. Air Quality in the Year 2050 |
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The potential impact of global climate change on future air quality in the United States is investigated with global and regional-scale models. Regional climate model scenarios ar...
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Linking Global to Regional Models to Assess Future Climate Impacts on Surface Ozone Concentrations in the United States |
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The UCD sectional aerosol model has been coupled to the CMAQ air quality model and used to simulate air quality in Tampa, Florida. Sea salt emissions are parameterized as a functi...
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Linking Watershed Atrazine and PCB Loads to Lake Michigan |
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An introduction, overview, and results of mathematical modeling in Lake Michigan. The presentation focuses on model mass balances and forecasts for atrazine and PCBs. The mass ba...
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Living waters: Connection and separation in water from physical, legal, political, and spiritual perspectives |
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Water is a dominant material on the Earth’s surface, covering most of the planet. Water significantly shapes land through the hydrologic cycle. Water is essential to all life, an...
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Loss of Virus-Specific Memory T. cells in Coxsackievirus B3 and B4 Infected Mice |
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There are two major types of enteroviruses: polioviruses and non-polio enteroviruses. While vaccines have effectively eliminated poliovirus infections, no vaccine is currently avai...
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Low dose-response for benzo[a]pyrene induced stable DNA adducts and gene expression in strain A/J mouse lung |
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Benzo[a]pyrene (B[a]P) is a potent human and rodent lung carcinogen. The current EPA cancer risk assessment of B[a]P assumes that the risk posed by low level e...
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MECHANISMS OF NANODIAMOND PARTICLE INDUCED IL-8 EXPRESSION IN HUMAN AIRWAY EPITHELIAL CELLS |
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Nanodiamond particles (NDP) prepared by detonation under confined conditions have a number of industrial and analytical applications. Previous in vitro studies have reported NDP to...
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MERCURY AND STABLE ISOTPOES OF CARBON AND NITROGEN IN MINK |
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The total mercury concentrations, δ15N and δ13C in tissues of mink (Mustela vison) captured in Rhode Island during winters of the years 1999-2004 showed samples to be statisticall...
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METABOLOMICS AS A TOOL FOR DISCRIMINATING AMONG ADAPTIVE, COMPENSATORY, AND TOXIC RESPONSES UPON EXPOSURE OF SMALL FISH TO EDCS |
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Determining the impact(s) of exposure on aquatic organisms by endocrine disrupting compounds (EDCs) is essential for determining the risks that these chemicals pose. However, to a...
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METAL RELEASE FROM BOTTOM SEDIMENTS OF OCOEE LAKE NO. 3, A PRIMARY CATCHMENT AREA FOR THE DUCKTOWN MINING DISTRICT |
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Ocoee Lake No. 3 is the first reservoir receiving suspended
sediments contaminated with trace metals discharged by acid
mine effluents from the Ducktown Mining District, Tennesse...
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METHODS FOR AQUATIC RESOURCE ASSESSMENT (MARA) FY 2008 - 2012 |
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For the past 17 years, members of the Freshwater Ecology Branch (FEB) at EPA’s Western Ecology Division (WED) have been engaged in research to develop the concepts and tools that w...
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MICROWAVE IRRADIATION IN BENIGN SYNTHESIS OF ORGANIC MOLECULES, NOBLE NANOMETALS AND NANOCOMPOSITES |
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A brief historic account of reactions involving microwave (MW) exposure of neat reactants or catalyzed by mineral support surfaces, such as alumina, silica, clay, or their ‘doped’ ...
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MNA of Inorganic Contaminants: Contrasting Behavior of Base Metals and Oxyanions |
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EPA’s Office of Research and Development has recently prepared technical resource documents for the application of MNA to inorganic contaminants in groundwater. These documents pr...
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MODELING APPROACHES FOR ESTIMATING THE DOSIMETRY OF INHALED TOXICANTS IN CHILDREN |
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Risk assessment of inhaled toxicants has typically focused upon adults, with modeling used to extrapolate dosimetry and risks from laboratory animals to humans. However, behaviora...
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MODELING ENERGY EXPENDITURE AND OXYGEN CONSUMPTION IN HUMAN EXPOSURE MODELS: ACCOUNTING FOR FATIGUE AND EPOC |
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Human exposure and dose models often require a quantification of oxygen consumption for a simulated individual. Oxygen consumption is dependent on the modeled Individual's physical...
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MODELING LONG-TERM DYNAMICS OF LITTER ACCUMULATION IN RESPONSE TO STATIC AND VARIABLE HYDROPERIODS |
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Accumulated litter from emergent species like the cattail hybrid (Typha glauca Godr.) can influence local abiotic conditions, other biota, and ecosystem processes. Litter accumulat...
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MODELING POPULATION EXPOSURES TO OUTDOOR SOURCES OF HAZARDOUS AIR POLLUTANTS |
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Accurate assessment of human exposures is an important part of environmental health effects research. However, most air pollution epidemiology studies rely upon imperfect surrogat...
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MODELING THE TOXICOKINETICS OF INHALED TOLUENE IN RATS: THE IMPACT OF CONDITIONING AND PHYSICAL ACTIVITY |
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Toluene is found in petroleum-based fuels and used as a solvent in consumer products and industrial applications. The critical effects following inhalation exposure involve the br...
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MRA Research Activities to Support Drinking Water Standards |
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Slide Presentation for the Joint U.S. EPA and Department of Homeland Security Conference on Real-World Applications and Solutions for Microbial Risks Assessment, Bethesda, MD, Apri...
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MULTIPLE REGRESSION MODELS FOR HINDCASTING AND FORECASTING MIDSUMMER HYPOXIA IN THE GULF OF MEXICO (ABSTRACT) |
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Abstract for presentation...
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Making Connections between Coastal Landscapes and Coastal Ecosystems (Presentation to Graduate Students) |
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This presentation is to graduate students in Integrated Biological Sciences. It intends to illustrate a problem and the accompanying research and development approach to designing...
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Managing Saginaw Bay nutrient loading by surrounding watersheds through near real time hydrologic resource sheds |
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We can quantify source areas contributing material to a location during various time periods as resource sheds. Various kinds of resource sheds and their source material distributi...
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Mapping estuarine distributions of the non-indigenous Japanese Eelgrass Zostera japonica using Color Infrared Aerial Photography |
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This presentation describes a technique for mapping distributions of the nonindigenous Japanese eelgrass Zostera japonica in estuarine ecosystems of the Pacific Northwest. The rel...
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Mapping isolated wetlands with GIS and remote sensing in North Central Florida, USA |
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Wetlands perform many functions on the landscape related to water quality and quantity, and provide habitat for myriad organisms. The identification of wetlands can be problematic,...
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Mappping isolated wetlands with GIS and remote sensing in North Central Florida USA |
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Presentation at the ENVIROMIS 2008 international conference on environmental observations, modeling and information systems, Tomsk, Russia, June 28 - July 6, 2008....
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Mechanisms of perfluoroalkyl acid (PFAA) toxicity: Involvement of peroxisome proliferator activator receptor alpha (PPAR) molecular signals. |
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Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) are members of a family of environmentally persistent perfluorinated compounds and are found in the serum of wild...
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Mechanistic Indicators of Childhood Asthma (MICA) Study |
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The Mechanistic Indicators of Childhood Asthma (MICA) Study has been designed to incorporate state-of-the-art technologies to examine the physiological and environmental factors th...
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Mechanistic Investigation of the Non-Cytochrome P450 Mediated Metabolism of Triadimefon and Implications for Toxicity |
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Triazole containing compounds have been used for decades as agricultural and medicinal fungicides. Recently, emphasis has been placed on the potential adverse effects of these com...
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Meeting at Temple University: An Update on U.S. Gasoline Composition |
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There is no abstract for this product. If further information is requested, please refer to the bibliographic citation and contact the person listed under Contact field....
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Meeting at Yale University: The Next Generation of Disinfection By-Products |
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Slide presentation on drinking water disinfection by-products....
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Meeting in Atlanta: An Update on U.S. Gasoline Composition |
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There is no abstract for this product. If further information is requested, please refer to the bibliographic citation and contact the person listed under Contact field....
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Meeting in Atlanta: Lead Scavengers in Old Product Samples: An EPA Evaluation |
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Slide presentation presented at the ASTWMO meeting on MTBE and other fuel additives on lead scavengers in old product samples. ...
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Meeting in Canada: Chlorinated vs. Chloraminated Drinking Water: Toxicity-Based Identification of Disinfection By-Products Using ESI-MS and ESI-MS/MS |
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Drinking water disinfection by-products (DBPs) are of concern because epidemiologic studies have shown that they are associated with bladder cancer and adverse reproductive/develop...
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Meeting in Korea: WASP Transport Modeling and WASP Ecological Modeling |
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A combination of lectures, demonstrations, and hands-on excercises will be used to introduce pollutant transport modeling with the U.S. EPA's general water quality model, WASP (Wat...
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Meeting in New Orleans: An Assessment of the Fate of Metal Oxide Nanomaterials in Porous Media |
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This work assesses potential aqueous environmental metal oxide nanomaterial self-aggregation through the application of recent developments in surface complexation theory with hist...
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Metabolic Changes Caused by Ethinylestradiol in Human Breast Cancer Cells as Observed by NMR Spectroscopy |
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To conduct cell culture based metabolomics, we have developed a novel sample preparation method using adherent mammalian cells, which is rapid, effective, and exhibits greater meta...
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Metal Immobilization Influence On Bioavailability And Remediation For Urban Environments |
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Immobilization of soil contaminants, such as lead, via phosphate amendments to alter the chemical environment of metals into highly insoluble forms is a well established process. T...
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Meteorological influences on algal bloom potential in a nutrient-rich blackwater river |
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The effect of variability in rainfall on the potential for algal blooms was examined for the St. Johns River in northeast Florida. Water chemistry and phytoplankton data were colle...
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Method Development for the Determination of Fluorotelomer Alcohols in Soils by Gas Chromatography Mass Spectrometry |
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Fluorotelomer alcohols (FTOHs) have been widely studied as precursors to perfluorocarboxylates, e.g. 8:2 FTOH degrades to perfluorooctanoic acid (PFOA). This presentation describes...
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Methods for Measuring Occurrence and Exposure From Viruses in Drinking and Recreational Water |
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The United States Environmental Protection Agency (EPA) has an active research program to develop and improve methods for detecting human enteric viruses in recreational, source, a...
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Microbial As(III) Oxidation in Water Treatment Plant Filters |
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Arsenic exists in two oxidation states in water - arsenite [As(III)] and arsenate [As(V)]. As(III) is relatively mobile in water and difficult to remove by arsenic-removal treatmen...
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Microbial Risk Assessment: Underpinning Research Needs for Recycled Water |
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Slide Presentation to be presented at the 12th Annual Water Reuse and Desalination Research Conference, Denver, Colorado, May 5-6, 2008...
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Microsatellite loci for the invasive colonial hydrozoan Cordylophora caspia |
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Cordylophora caspia, a colonial hydrozoan native to the Ponto-Caspian region, has become a common invader of both fresh and brackish water ecosystems of North America and Europe. ...
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Microwave-Assisted Organic Synthesis Using Benign Reaction Medium and Reagents |
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Account of chemical reactions expedited by microwave (MW) exposure of neat reactants for the rapid one-pot assembly of heterocyclic compounds from in situ generated reactive interm...
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Microwave-Assisted Synthesis of Nanomaterials and Nanocomposites |
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The aqueous preparation of nanoparticles using vitamins B1 and B2, and vitamin C which can function both as reducing and capping agents prompted us accomplished the bulk syntheses ...
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Microwave-assisted one-pot synthesis of ring-fused aminals under catalyst- and solvent-free conditions |
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Heterocyclic compounds hold a special place in drug discovery and variety of techniques such as combinatorial synthesis, parallel synthesis, and automated library production to inc...
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Microwave-assisted transformations and synthesis of polymer nanocomposites and nanomaterials |
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The use of emerging MW-assisted chemistry techniques in conjunction with greener reaction media is dramatically reducing chemical waste and reaction times in several organic transf...
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Mitochondrial biogenesis in the pulmonary vasculature during inhalation lung injury and fibrosis |
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Cell survival and injury repair is facilitated by mitochondrial biogenesis; however, the role of this process in lung repair is unknown. We evaluated mitochondrial biogenesis in th...
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Modeled Watershed Runoff Associated with Variations in Precipitation Data with Implications for Contaminant Fluxes |
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Watershed-scale fate and transport models are important tools for estimating the sources, transformation, and transport of contaminants to surface water systems. Precipitation is o...
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Modeling Analyses of the Effects of Changes in Nitrogen Oxides Emission from the Electric Power Sector on Ozone Levels in the Eastern United States |
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This modeling study tests a hypothetical scenario to see what air quality might have looked like if no emission controls had been placed on electric generating units, as required b...
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Modeling Single and Repeated Dose Pharmacokinetics of PFOA in Mice |
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Perfluorooctanoic acid (PFOA) displays complicated pharmacokinetics in that plasma serum concentration indicates a long half life – 3.8 years in humans (Olsen et al. 2007) – but al...
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Modeling Watershed Mercury Response to Atmospheric Loadings: Response Time and Challenges |
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The relationship between sources of mercury to watersheds and its fate in surface waters is invariably complex. Large scale monitoring studies, such as the METAALICUS project, have...
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Modeling the Pharmacokinetics of Perfluorooctanoic Acid During Gestation and Lactation In Mice |
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Perfluorooctanoic acid (PFOA) is used as a processing aid for the production of commercially valuable fluoropolymers and fluoroelastomers. It has been widely detected in biological...
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Mold Species in Dust from the International Space Station Identified and Quantified by Mold Specific Quantitative PCR - MCEARD |
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Dust was collected over a period of several weeks in 2007 from HEPA filters in the U.S. Laboratory Module of the International Space Station (ISS). The dust was returned on the S...
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Molecular Characterization of a Functional Type VI Secretion System from a Clinical Isolate of Aeromonas hydrophilia |
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Our laboratory recently molecularly characterized the type II secretion system (T2SS)-associated cytotoxic enterotoxin (Act) and the T3SS-secreted AexU effector from a diarrheal is...
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Molecular Genotyping of Viable Cryptosporidium Oocysts |
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Cryptosporidium is a chlorination-resistant protozoan parasite that causes a self-limiting diarrheal disease in the immunocompetent or severe chronic diarrhea in the immunocompromi...
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Molecular techniques from a regulatory perspective |
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Presentation at the 5th SETAC World Congress, Sydney, Australia, August 3-7, 2008...
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Molybdenum Accumulation in Marine Sediments as an Indicator of Hypoxic Water Conditions (NACAETAC) |
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Direct monitoring of hypoxic water column conditions over large spatial and temporal extents is difficult due to the substantial logistical and financial investment required. Recen...
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Monitored Natural Attenuation of Inorganic Contaminants in Ground Water – Technical Report Series |
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This presentation will cover the development and content of new EPA Technical Resource Documents on the application of monitored natural attenuation for inorganic contaminants in g...
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Monitoring dredging effectiveness using biological and chemical markers of exposure in brown bullheads and benthic macroinvertebrates |
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Sediments in portions of the Ashtabula River in Northeastern, Ohio are heavily contaminated with polychlorinated biphenyls (PCBs), and the river has been designated by the Internat...
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Monitoring the Effectiveness of Measures to Contain the Primary Sources of Mercury Pollution on the Site of a Former Chlor-Akali Plant in Kazakhstan |
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An extensive sampling campaign was conducted in 2005-2007 to monitor the effectiveness of remedial measures to contain mercury pollution at the site of a former mercury cell chlor-...
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Monitoring the expanding distribution of non-indigenous dwarf eelgrass Zostera japonica in a Pacific Northwest USA estuary using high-resolution digital aerialphotomaps |
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The proliferation of non-indigenous species is a world-wide issue. Environmental managers need improved methods of detecting and monitoring the distribution of such invaders over ...
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Moving from the laboratory to the field: Adding natural environmental conditions to toxicology testing |
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While laboratory toxicology tests are generally easy to perform, cost effective and readily interpreted, they have been criticized for being unrealistic. In contrast, field tests ...
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Multi-Chambered Treatment Train (MCTT) For Treating Stormwater Runoff From Highly Polluted Source Areas |
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A full-scaled Multi-Chambered Treatment Train (MCTT) stormwater treatment system was tested in Taiwan during the spring and summer of 2007. The MCTT was installed in a parking lot ...
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NANOMATERIAL HEALTH EFFECTS RESEARCH CONTRIBUTES TO RISK MANAGEMENT STRATEGIES THROUGH THE RISK ASSESSMENT PARADIGM |
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Nanotechnology continues to produce a diversity of engineered nanomaterials displaying novel physicochemical properties with applications in commercial, consumer, electronic, biome...
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NATIONAL LAKE ASSESSMENT MONITORING DESIGN |
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The USEPA designed the National Lake Assessment in 2005-6 with field sampling being completed in 2007. The objective of the assessment is to estimate the ecological condition of l...
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NET ANTHROPOGENIC PHOSPHORUS INPUTS; SPATIAL AND TEMPORAL VARIABILITY IN THE CHESAPEAKE BAY REGION |
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Coastal watershed eutrophication has increasingly become a regional and global issue as larger proportions of the earth’s human population settle in coastal areas. Human activitie...
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NEUROSENSORY EFFECTS OF CHRONIC HUMAN EXPOSURE TO ARSENIC ASSOCIATED WITH BODY BURDEN AND ENVIRONMENTAL MEASURES |
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Exposure to arsenic in drinking water is known to produce a variety of
health problems including peripheral neuropathy. Auditory, visual and
somatosensory impairments have be...
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NON-TRADITIONAL RESPONSES TO PHARMACEUTICALS IN AQUATIC ECOSYSTEMS |
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Quantitation of human and veterinary pharmaceuticals in environmental matrices has resulted in pharmaceuticals in the environment receiving unprecedented attention from the scienti...
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NOVEL INSIGHTS INTO THE MECHANISM OF SUBCHRONIC AIR POLLUTANT-INDUCED CARDIOVASCULAR IMPAIRMENT |
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The mechanisms by which air pollutants induce cardiovascular mortality are unknown. We hypothesized that blood vessels are the target of injury by circulating oxidation by-products...
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NRMRL Green Infrastructure Research |
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Solution: Build demonstration site
• Reasonable scale
• Introduce “some” level of control
• Improved QA/QC
• Educational outreach / demonstration site
• Collaborative opportun...
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NTP-CERHR Expert Panel Report on the Reproductive and Developmental Toxicity of Bisphenol A |
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The National Toxicology Program (NTP)1 established the NTP Center for the Evaluation of Risks to Human Reproduction (CERHR) in June 1998. The purpose of the CERHR is to provide tim...
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Natural Anaerobic Biodegradation of TBA in Aquifer Sediments at Gasoline Spill Sites |
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TBA is an important contaminant at spills sites of gasoline that contains MTBE. The impact of TBA is particularly important in Southern California, where the State Action Level for...
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Neighborhood deprivation and preterm birth among non-Hispanic black and white women in eight geographic areas in the United States |
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Disparities in preterm birth by race and ethnic group have been demonstrated in the United States. Recent research focuses on the impact of neighborhood environmental context on r...
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Nekton-habitat associations in Yaquina Bay, Oregon - March 2008 |
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We conducted a 3-year field study to determine the relative nekton usage of 4 intertidal habitats (eelgrass [Zostera marina], mud shrimp [Upogebia pugettensis], ghost shrimp [Neotr...
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Neurobehavioral toxicity testing for risk assessment. |
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Neurobehavioral evaluations are key components in neurotoxicity testing. In the realm of regulatory testing, these evaluations range from a functional observational battery (FOB) ...
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Neurotoxicity and Immunotoxicity Outcomes following Gestational Exposure to Four Lab Drinking Water Concentrates |
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To evaluate whether developmental exposure to drinking water concentrates altered other endpoints, standard neuro- and immunotoxicity tests were conducted on the offspring. Male a...
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New Toxico-Cheminformatics & Computational Toxicology Initiatives At EPA |
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EPA’s National Center for Computational Toxicology is building capabilities to support a new paradigm for toxicity screening and prediction. The DSSTox project is improving public ...
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Next steps for the National Wetlands Condition Assessment |
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The U.S. Environmental Protection Agency (EPA) anticipates conducting a national survey of wetland condition, with field work scheduled for 2011 and a report in 2013. This session...
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Nitorgen Effects on Coastal Marine Ecosystems(Update) |
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This is an updated review and synthesis of a chapter written in 2001. The update primarily discusses an enlarging scale of the issue and some changing perspectives on how to resea...
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Nowcasting and Forecasting Concentrations of Biological Contaminants at Beaches: A Feasibility and Case Study |
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Public concern over microbial contamination of recreational waters has increased in recent years. A common approach to evaluating beach water quality has been to use the persistenc...
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Numerical Modeling of One-Dimensional Steady-State Flow and Contaminant Transport in a Horizontally Heterogeneous Unconfined Aquifer with an Uneven Base |
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Algorithms and a short description of the D1_Flow program for numerical modeling of one-dimensional steady-state flow in horizontally heterogeneous aquifers with uneven sloping bas...
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Numerical Quantification of Perkinsus Marinus in the American Oyster Crassostrea virginicata (Gmelin 1791) (Mollusca: Bivalvia) by Modern Stereology |
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Species of Perkinsus are responsible for high mortalities of bivalve molluscs world-wide. Techniques to accurately estimate parasites in tissues are required to improve understandi...
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OBSERVABLE INDICATORS OF THE SENSITIVITY OF PM2.5 NITRATE TO EMISSION REDUCTIONS PART I: DERIVATION OF THE ADJUSTED GAS RATIO AND APPLICABILITY AT REGULATORY-RELEVANT TIME SCALES |
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Chemical transport models have frequently been used to evaluate the impacts of emission reductions on inorganic PM2.5. However, such models are limited in their accuracy by uncert...
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OCCURRENCE, GENOTOXICITY, AND CARCINOGENICITY OF EMERGING DISINFECTION BY-PRODUCTS IN DRINKING WATER: A REVIEW AND ROADMAP FOR RESEARCH |
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Occurrence, Genotoxicity, and Carcinogenicity of Emerging Disinfection By-products in Drinking Water: A Review and Roadmap for Research
Summary of Paper
What is study?...
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ORD Technical Outreach and Support Activities on Sustainable Mining Applications |
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Hardrock mining has played a significant role in the development of economies, consumer products and defense in the United States from the start of industrialization. Currently, t...
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ORIGINS AND TEMPORAL SCALES OF HYPOXIA ON THE LOUISIANA SHELF: IMPORTANCE OF BENTHIC AND SUB-PYCNOCLINE WATER METABOLISM |
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Hypoxic-to-anoxic conditions (2–0 mg O2 l− 1) occur in the bottom waters of the northern Gulf of Mexico on the Louisiana shelf west of the Mississippi river delta during late sprin...
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OVERVIEW OF EXPOSURE TO DIOXIN-LIKE COMPOUNDS AND PCBS ON DEVELOPMENTAL, IMMUNOSUPPRESSIVE, AND HORMONE-RELATED EFFECTS IN MAMMALS, INCLUDING HUMANS |
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Exposure to TCDD and related compounds leads to a plethora of effects in multiple species, tissues and stages of development. The response spectrum ranges from simple biochemical ...
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OVERVIEW OF VOLLUNTARY STEWARDSHIP EFFORTS TO ADDRESS PHARMACEUTICAL DISPOSAL |
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This presentation will provide an overview of current federal regulatory guidance for pharmaceutical disposal, currently funded pilot programs for take-back pilot studies, and stat...
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OVERVIEW ON ALTERNATIVE ASBESTOS CONTROL METHOD RESEARCH |
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The alternative asbestos control method (AACM) is an experimental approach to building demolition. Unlike the NESHAP method, the AACM allows some regulated asbestos-containing mat...
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Obesity and perinatal TCDD exposure increases mammary tumor incidence in FVB mice |
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Breast cancer risk consistently correlates with total lifetime exposure to estrogens. Because both TCDD and adipocytes impact the estrogen pathway, we examined how TCDD and obesit...
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Obesity and perinatal TCDD exposure increases mammary tumors in FVB mice |
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Risk of breast cancer has been consistently shown to correlate to total lifetime exposure to estrogens. Because both TCDD exposure and the state of obesity interact with the estro...
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Occurrence, Synthesis and Mammalian Cell Cytotoxicity and Genotoxicity of Haloacetamides: An Emerging Class of Nitrogenous Drinking Water Disinfection By-Products |
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The haloacetamides, a class of emerging nitrogenous drinking water disinfection by-products (DBPs), were analyzed for their chronic cytotoxicity and for the induction of genomic DN...
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Oligomers Formed Through In-cloud Metylglyoxal Reactions: Chemical Composition, Properties, and Mechanisms Investigated by Ultra-high Resolution FT-ICR Mass Spectrometry |
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Secondary organic aerosol (SOA) is a substantial component of total atmospheric organic particulate matter, but little is known about the composition of SOA formed through cloud pr...
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Organic Carbon as Inhibitor to SVOC and Metal Migration in Stormwater Drywells Discharging to the Subsurface-SLIDES |
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The Safe Drinking Water Act (SDWA) authorizes the Underground Injection Control (UIC) program to protect underground drinking water (USDW) sources from contamination caused by unde...
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Organic Carbon-water Column Concentration Quotients: Measuring Chemical Disequilibrium and Exploring the Impact of Black Carbon in Lake Michigan |
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When black carbon (bc) and biologically derived organic carbon (bioc) phases are present in sediments or suspended particulates, both forms of carbon act additively to sorb organic...
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Organic Matter Sources Supporting Lower Food Web Production in the Tidal Freshwater Portion of the York River Estuary, Virginia |
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This manuscript presents novel findings on the role of terrestrial organic carbon in an estuary ecosystem. We show that, contrary to current thinking, terrestrial carbon can suppo...
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Organophosphorus (OP) Pesticide Degradation in the Presence of Chlorinated Oxidants: Kinetics, Modeling, and Structure-Activity Relationships |
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The rates and pathways for pesticide transformation during drinking water treatment are known for only a few pesticides and under limited conditions. The resulting oxons are more t...
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Overview On Alternative Asbestos Control Method Research: Alternative Methods To Demolition |
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The Alternative Asbestos Control Method (AACM) is an experimental approach to building demolition. Unlike the NESHAP method, the AACM allows some regulated asbestos-containing mat...
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Overview of ToxCast |
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In 2007, EPA launched ToxCast™ in order to develop a cost-effective approach for prioritizing the toxicity testing of large numbers of chemicals in a short period of time. Using da...
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Overview of USEPA's ORD Technical Outreach and Support Activities on Vapor Intrusion Impacts - 03/2008 |
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The science of determining, characterizing and managing vapor intrusion risks is constantly evolving. Much remains to be done in assisting regulators, consultants and other decisio...
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Overview of current TEFs as it relates to current PCB exposures: What is needed? |
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The toxic equivalency factor (TEF) approach is one of the ways to assess the risk associated with exposure to complex mixture of polychlorinated biphenyls (PCBs) and structurally r...
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Overwintering Habitats of Migratory Juvenile American Shad in Chesapeake Bay |
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We describe overwintering habitats of age-0 American shad in the lower Chesapeake Bay estuary through analyses of multiple, complementary
data sets, including bottom-trawls of the...
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P2.4 SPECIATE - EPA's Database for Speciated Emission Profiles |
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SPECIATE, is the U.S. Environmental Protection Agency’s (EPA) repository of total organic compound (TOC) and particulate matter (PM) speciation profiles for emissions from air poll...
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PAHs in the Lake Michigan Aquatic Ecosystem |
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These data will augment efforts to reduce large uncertainties in risk assessments and water quality criteria developed for PAHs....
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PARAMETRIC DISTANCE WEIGHTING OF LANDSCAPE INFLUENCE ON STREAMS |
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We present a parametric model for estimating the areas within watersheds whose land use best predicts indicators of stream ecological condition. We regress a stream response variab...
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PARTIAL LEAST SQUARES (PLS) REGRESSION FOR SMALL SAMPLE WITH COLLINEAR PREDICTORS IN LANDSCAPE ECOLOGY |
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The primary objective of the U.S. Environmental Protection Agency's (EPA) Landscape Ecology research program is investigation of associations between surface water constituents and...
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PBPK MODELING OF DELTAMETHRIN IN RATS |
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The pyrethroid pesticide deltamethrin is cleared nearly twice as rapidly in human liver microsomes compared to rat liver microsomes. A species difference such as this could influen...
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PCDD/F and Aromatic Emissions from Simulated Forest and Grassland Fires |
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Emissions of polychlorinated dibenzodioxin and polychlorinated dibenzofuran (PCDD/F) from simulated grassland and forest fires were quantitatively sampled to derive emission factor...
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PCEIS - THE PACIFIC COAST ECOSYSTEM INFORMATION SYSTEM, CHANGING THE WAY SCIENTISTS VIEW THE NATURAL HISTORY OF SPECIES |
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The Pacific Coast Ecosystem Information System (PCEIS) is a database that provides biological, ecological and geospatial information for over 8100 species from Alaska to Baja. PCEI...
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PERSISTENT EFFECTS OF REPEATED INHALATION OF TOLUENE: 4 WEEKS VS. 13 WEEKS. |
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Understanding and predicting the extent of neurotoxic damage from repeated exposure to volatile organic compounds (VOCs) is a problem for many EPA programs. Eighty adult, male Long...
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PFOS and PFOSA in Bottlenose Dolphins: An Investigation into Two Unusually High Mortality Epizootics |
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Along the Atlantic coast of the United States during 1987 and 1988, bottlenose dolphins (Tursiops truncatus) suffered one of this country's largest marine mammal mass mortality eve...
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PFOS and PFOSA in Bottlenose Dolphins: An Investigation into Two Unusually High Mortality Events |
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Along the Atlantic coast of the United States during 1987 and 1988, bottlenose dolphins (Tursiops truncatus) suffered one of this country's largest marine mammal mass mortality eve...
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PHARMACEUTICALS AND PERSONAL CARE PRODUCTS (PPCPS) AS ENVIRONMENTAL POLLUTANTS: AN OVERVIEW OF THE SCIENCE |
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Presentation materials. If further information is requested, please refer to the bibliographic citation and contact the person listed under Principal Investigator....
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PHOTOBIOGEOCHEMISTRY OF SARGASSUM: A POTENTIALLY IMPORTANT SOURCE OF CHROMOPHORIC DISSOLVED ORGANIC MATTER IN THE UPPER OCEAN |
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Sargassum is a genus of widely distributed, generally planktonic macroalgae that often is found near the surface of the ocean. Here we report that a consortium of commonly occurrin...
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PLANNING THE WEDDING: DEVELOPMENT BASED UPON ECOSYSTEMS |
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Changing land uses to meet needs and expectations of the growing human population is largely responsible for habitat loss, species extinctions, deterioration of water quality and ...
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POLLEN FLOW IN THE ENVIRONMENT - DEVELOPMENT OF A RESEARCH PROGRAM |
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The USEPA Office of Research and Development seeks to provide to the agency and society the best information relating to the status of the environment and any related technology ma...
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POLYCHLORINATED BIPHENYLS (PCBS) AND POLYBROMINATED DIPHENYL ETHERS (PBDES)IN CURRENT AND HISTORICAL SAMPLES OF AVIAN EGGS FROM NESTING SITES IN BUZZARDS BAY, MA |
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Poster presentation at a national scientific meeting...
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POLYMORPHIC MICROSATELLITE LOCI FROM NORTHERN AND MEXICAN CORN ROOTWORMS (INSECTA: COLEOPTERA: CHRYSOMELIDAE) AND CROSS-AMPLIFICATION WITH OTHER DIABROTICA SPP |
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The northern corn rootworm (Diabrotica barberi) and Mexican corn rootworm (Diabrotica virgifera zeae) are significant agricultural pests. For the northern corn rootworm, and to a l...
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POSSIBLE MECHANISMS OF THYROID HORMONE DISRUPTION IN MICE BY BDE 47, A MAJOR POLYBROMINATED DIPHENYL ETHER CONGENER |
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ABSTRACT
Polybromindated diphenyl ethers (PBDEs) are a class of polyhalogenated aromatic compounds commercially used as fire retardants in consumer products. These compounds hav...
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POTENTIATION OF PULMONARY REFLEX RESPONSE TO CAPSAICIN 24 HOURS FOLLOWING WHOLE-BODY ACROLEIN EXPOSURE IS MEDIATED BY TRPV1 |
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Pulmonary C-fibers are stimulated by irritant air pollutants producing apnea, bronchospasm, and decrease in HR. C-fiber chemoreflex activation is mediated by TRPV1 and release of ...
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PREDICTING ESTUARINE SEDIMENT METAL CONCENTRATIONS AND INFERRED ECOLOGICAL CONDITIONS: AN INFORMATION THEORETIC APPROACH |
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Empirically derived values associating sediment metal concentrations with degraded ecological conditions provide important information to assess estuarine condition. However, reso...
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PREDICTIVE MODELING OF LIGHT-INDUCED MORTALITY OF ENTEROCOCCI FAECALIS IN RECREATIONAL WATERS |
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One approach to predictive modeling of biological contamination of recreational waters involves the application of process-based approaches that consider microbial sources, hydrody...
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PREFACE: MARINE AND COASTAL APPLICATIONS IN LANDSCAPE ECOLOGY |
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Landscape ecology traditionally has been limited to the study of terrestrial systems; however, the questions and methods defining the science are equally relevant for marine and c...
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PREGNANCY AND PERINATAL HEALTH, INNER MONGOLIA, CHINA, DECEMBER 1996-DECEMBER 1999 |
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Pregnancy and Perinatal Health, Inner Mongolia, China, December 1996- December 1999
Subtitle: Pregnancy and Perinatal Health, Inner Mongolia, China
Authors: Z. Liu1, D.T. Lo...
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PRELIMINARY RESULTS: EVALUATIONS OF THE ALTERNATIVE ASBESTOS CONTROL METHOD FOR BUILDING DEMOLITION |
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This presentation describes the preliminary results of the evaluations of the alternative asbestos control method for demolishing buildings containing asbestos, and are covered und...
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PRELIMINARY STEPS TOWARDS INTEGRATING CLIMATE AND LAND USE (ICLUS): THE DEVELOPMENT OF LAND-USE SCENARIOS CONSISTENT WITH CLIMATE CHANGE EMISSIONS STORYLINES (EXTERNAL REVIEW DRAFT) |
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This report was prepared by the Global Change Research Program in the National Center for Environmental Assessment (NCEA) of the Office of Research and Development (ORD) at the U.S...
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PRIMARY AND SECONDARY CONTRIBUTIONS TO AMBIENT PM IN THE MIDWESTERN UNITED STATES |
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Ambient PM2.5 samples were collected in five Midwestern US cities throughout 2004: East St. Louis, Illinois; Detroit, Michigan; Cincinnati, Ohio; Bondville, Illinois; an...
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PRIONS AND THE TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES |
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This book chapter is an invited, scholarly review of the mechanism(s) of TSEs for the 2nd edition of Metabolic Encephalopathies. Each chapter in the book assumes a professional kno...
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PROPERTY CHANGES IN AQUEOUS SOLUTIONS DUE TO SURFACTANT TREATMENT OF PCE: IMPLICATIONS TO GEOPHYSICAL MEASUREMENTS |
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Select physicochemical properties of aqueous solutions composed of surfactants, dye, and
perchloroethylene (PCE) were evaluated through a response surface quadratic design |
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PROPICONAZOLE-INDUCED CARCINOGENESIS: ROLE OF OXIDATIVE STRESS |
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Propiconazole is a systemic foliar fungicide with a broad range of activity. Rodents fed with propiconazole at high dose resulted in diminished body weight, increased liver weight ...
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PROTEOMIC PROFILING OF CULTURED HUMAN BLADDER CELLS AFTER TRIVALENT ARSENICAL EXPOSURES (SOT 2008) |
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Chronic exposure to arsenic has been associated with human cancers of the bladder, kidney, lung, liver, and skin. Inorganic arsenic is biotransformed in a stepwise manner via both ...
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PROTEOMICS IN ECOTOXICOLOGY: PROTEIN EXPRESSION PROFILING TO SCREEN CHEMICALS FOR ANDROGENIC ACTIVITY. |
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Abstract for presentation....
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PULMONARY TOXICITY OF SIZE-CLASSIFIED COAL FLY ASH PARTICLES OF VARYING CARBON CONTENT |
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Epidemiological studies have shown that morbidity and mortality increase along with concentration of particulate matter (PM) in many different countries and regions despite great v...
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PYRETHROID MODULATION OF SPONTANEOUS NEURONAL EXCITABILITY AND NEUROTRANSMISSION IN HIPPOCAMPAL NEURONS IN CULTURE |
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Pyrethroid insecticides have potent actions on voltage-gated sodium channels, inhibiting inactivation and increasing channel open times. These are thought to underlie, at least in ...
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Partitioning and Phase Behavior of Ethanol Fuel Blends |
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Presentation at the 2008 International Oil Spill Conference in May 2008....
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Past, Present & Future of the US EPA: Protecting Human Health & the Natural Environment |
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The time line of events that lead to the creation of the US EPA are marked by grassroots efforts by average citizens voicing concerns to politicians in Washington. Visionary leader...
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Perfluorinated Compounds in House Dust from Ohio and North Carolina, USA |
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The perfluoroalkyl acids (PFAAs), including perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS), have come under increasing scrutiny due to their persistence in the ...
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Perfluoroalkyl acids and related chemistries Toxicokinetics and modes of action |
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The perfluoroalkyl acid salts (both carboxylates and sulfonates, hereafter designated as PFAAs) and their derivatives are important chemicals that have numerous consumer and indust...
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Performance Assessment of Human-Specific Microbial Source Tracking Assays End-Point PCR Assays |
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Waterborne diseases are a significant public health issue, and many originate from contact with water contaminated with human fecal material. Ensuring public water quality require...
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Perinatal exposure to PBDEs elevate systolic blood pressure in response to hyperosmotic stimulation in aged adult rats. |
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Polybrominated diphenyl ethers (PBDEs) are flame retardants used widely throughout the U S. These chemicals are persistent throughout the environment and accumulate in biota. In p...
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Permeable Pavement Research at NRMRL’s Urban Watershed Research Facility |
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The results of a bench-scale study of a porous pavement parking lot. Flow rates and total suspended solids (TSS) removal are discussed for systems with a geotextile filter fabric l...
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Permeable Pavement Research at NRMRL’s Urban Watershed Research Facility (Poster 2) |
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Assess pollutant removal efficiency of porous pavement systems with regard to parking lot runoff.
Bench-scale study will examine:
Discharge volume
Flow rate ...
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Pervious Pavement System Evaluation- Abstract 1 |
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Porous pavement is a low impact development stormwater control. The Urban Watershed Management Branch is evaluating interlocking concrete pavers as a popular implementation. The ...
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Pervious Pavement System Evaluation-Poster |
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Pervious pavement is a low impact development stormwater control. The Environmental Protection Agency's Urban Watershed Management Branch is evaluating interlocking concrete paving...
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Pharmacokinetic Modeling of Perfluoroalkyl Acids in Rodents |
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Perfluorooctanoic acid (PFOA) has pharmacokinetic properties that appear consistent with a number of processes that are currently not well understood. Studies in mice exposed oral...
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Phase 2, Determining the releasability of the asbestos fiber from soils and solid matrices. |
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Factors that affect the releasability or aerosolization of asbestos and related mineral fibers from a variety of sources need to be better understood to allow prediction and modeli...
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Phylogenetic Diversity and Membership Patterns of Fecal and Environmental Bacteroidales Populations |
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Members of the Bacteroidales order have recently been targets of microbial source tracking assays. While several studies have documented that some populations exhibit preferential ...
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Physical habitat in the national wadeable streams assessment |
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Effective environmental policy decisions require stream habitat information that is accurate, precise, and relevant. The recent National Wadeable Streams Assessment (NWSA) carried ...
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Physical indicators of hydrologic permanence in forested headwater streams |
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Recent court cases have brought headwater streams and their hydrologic permanence into the forefront for regulatory agencies, so rapid field-based indicators of hydrologic permanen...
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Pilot Plant Testing of Elemental Mercury Reemission from a Wet Scrubber (2) |
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This paper discusses the recent observations of elemental mercury (HgO) reemissions from a pilot-scale limestone wet scrubber. Simulated flue gas was generated by burning natural g...
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Pilot Scale In Situ BioTransformation Of Mercury-Contaminated Groundwater In Kazakhstan Utilizing Native Bacteria |
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The Northern outskirts of Pavlodar were contaminated with mercury as a result of activity at the former PO "Khimprom" chemical plant. The plant produced chlorine and alkali from t...
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Pipe and Solids Analysis: What Can I Learn? |
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This presentation gives a brief overview of techniques that regulators, utilities and consultants might want to request from laboratories to anticipate or solve water treatment and...
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Planning Sustainability: A Master Plan For Stella, Missouri |
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Human Life is conditional upon intact ecosystems that provide goods and services required to sustain human life. Because development will incrementally and cumulative consume the ...
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Polychlorinated Biphenyls (PCBs) and Polybrominated Diphenol Ethers (PBDEs) in Current and Historical Samples of Avian Eggs from Nesting Sites in Buzzards Bay, MA, USA |
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We measured concentrations of polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) in eggs from breeding colonies in Buzzards Bay, MA, USA. Eggs from two pi...
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Population viability impacts of habitat additions and subtractions: A simulation experiment with endangered kangaroo rats |
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Species viability is influenced by the quality, quantity and configuration of habitat. For species at risk, a principal challenge is to identify landscape configurations that, if...
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Potential exposure to human prescription pharmaceutical residues from wastewater |
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Pharmaceuticals in the environment (PiE) pose a complicated problem, involving multiple dissimilar compounds, multiple routes of potential exposure, and a range of potentially affe...
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Potential for Siting New Water Wells and Restoring Existing Wells in Arsenic-Impacted Aquifers |
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Studies have indicated that arsenic concentrations greater than the new U.S. Environmental Protection Agency (EPA) maximum contaminant level (MCL) concentration of 10 micrograms pe...
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Predicting Lactational and Early Post-Weaning Exposures in Rats Using Biologically Based Pharmacokinetic Modeling |
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Risk and safety assessments for early life exposures to environmental chemicals or pharmaceuticals based on cross-species extrapolation would greatly benefit from information on ch...
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Predicting Maternal Rat and Pup Exposures: How Different Are They? |
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Risk and safety assessments for early life exposures to environmental chemicals or pharmaceuticals based on cross-species extrapolation would greatly benefit from information on ch...
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Predicting Systems Behaviors in PK and PD Using Biologically Based Modeling of Rats & Mice |
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Slide presentation discusses biological modeling contexts, predicting PK, predicting PD, and regulatory accepetance of models....
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Prediction of Daily Flow Duration Curves and Streamflow for Ungauged Catchments Using Regional Flow Duration Curves |
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This study presents a method to predict flow duration curves (FDCs) and streamflow for ungauged catchments in the Mid-Atlantic Region, USA. We selected 29 catchments from the Appal...
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Predictive Modeling of Apical Toxicity Endpoints Using Data From ToxCast |
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The US EPA and other regulatory agencies face a daunting challenge of evaluating potential toxicity for tens of thousands of environmental chemicals about which little is currently...
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Pregnancy Outcome in a Multi-Generational Rat Bioassay of Drinking Water Concentrates in the Four Lab Study |
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To address concerns raised by epidemiological studies, we conducted a multigenerational reproductive toxicity study in rats using a “whole” mixture of drinking water disinfection b...
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Preliminary Results: Release Of Metals From Acid-Mine Drainage Contaminated Streambed Sediments Under Anaerobic Conditions (Presentation) |
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Many miles of streams in the western U.S. are contaminated with acid-mine drainage (AMD) from abandoned metal mines. Treatment of these streams may include removal of the existing ...
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Presence of Pharmaceuticals in Groundwater Down Gradient from Wastewater Lagoons Receiving Partially Treated Wastewater |
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Wastewater can contain traces of the pharmaceutical compounds that are used within a given household or community. These chemicals can act as markers of the wastewater, and their p...
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Presence of organic matter and microbial activity in Minebank Run, a restored stream in the Chesapeake Bay watershed |
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Abstract: Increasing nitrate levels in streams and ground water are harmful to both the environment and humans. Denitrification, a natural process performed by microbes, removes ni...
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Preventing Pollution from Biofuels Through A Knowledge Based Approach to Composition and Transport |
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The US has been subject to unexpected and costly fuel-related contamination problems. The composition, properties and behavior of fuels in the environment is problematic because th...
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Primary producers and nutrient loading in Silver Springs, FL, USA |
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The characteristics and dynamics of primary producer communities of Silver Springs was examined to compare with that observed by Odum as a means of evaulating the impacts of change...
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Primary productivity estimates in Gulf of Mexico waters: comparing in situ methods (FRRF,FIRe) with traditional techniques. |
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Abstract for presentation...
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Prioritizing Site-Selection And Use |
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Land subject to remediation is usually considered relative to its availability and its potential financial return-on-investment. Typically, these short-term considerations are unr...
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Production of Methane During Anaerobic Degradation of Ethanol in Gasoline |
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Field and laboratory studies show that the natural biodegradation of benzene may be inhibited by the presence of ethanol. Preferential biodegradation of ethanol can consume electr...
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Promising Emerging Mechanisms |
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Most applications of enhanced in situ bioremediation are based on biological reductive dechlorination. Anaerobic metabolism can also produce reactive minerals that allow for in si...
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Protecting and Restoring Streams in an Urbanizing World: Back to Square One |
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Headwater streams represent a majority (up to 70%) of the stream length in the United States. Because of their position and prevalence in the landscape, these small streams are of...
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Proteomic Analysis of Arsenic-Induced Oxidative Stress in Human Epidermal Keratinocytes |
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Chronic exposure to inorganic arsenic (IAs) has been associated with the development of several human cancers, including those found in the skin, lung, urinary bladder, liver, pros...
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Proteomic and Gene Expression Changes in the Fathead Minnow Liver in Response to Flutamide and Trenbolone Waterborne Exposure |
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This work demonstrates the utility of genomic tools in identifying candidate biomarkers for androgenic and antiandrogenic chemicals....
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Proteomic profiles of liver microsomes from mice treated with the hepatotumorigenic conazole, triadimefon |
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Abstract for Experimetnal Biology Meeting, April 2008...
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Pyrethroid Pesticides and Their Metabolites in Vacuum Cleaner Dust Collected from Homes and Day-Care Centers |
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The purpose of this study was to quantify the concentrations of 13 selected pyrethroid pesticides and their degradation products in samples of indoor dust that had been collected i...
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QUANTITATIVE TOXICOPROTEOMIC ANALYSIS OF CARCINOGEN-TREATED ANIMAL TISSUES AND HUMAN CELLS FOR HUMAN HEALTH RISK ASSESSMENT |
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Humans are exposed to a variety of environmental toxicants, and this together with a large number of interacting factors can contribute to an individual's risk for health. To under...
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Quantifying The Water Quality Services Of Wetlands |
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Wetlands are well recognized for their potential for providing a wide range of important ecological services including their ability to provide water quality protection. Watershed...
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Quantifying seasonal shifts in nitrogen sources to Oregon estuaries using a transport model combined with stable isotopes |
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Identifying the sources of dissolved inorganic nitrogen (DIN) in estuaries is complicated by the multiple sources, temporal variability in inputs, and variations in transport. We ...
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Quantitative Microbial Risk Assessment of Drinking Water - The Next Step |
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Presentation given at the Technische Universiteit Delft, Holland, The Netherlands, April 16, 2008...
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RAPID, AUTOMATED DETERMINATION OF ELEMENTAL COMPOSITIONS OF IONS IN MASS SPECTRA OBTAINED WITH AN OPEN-AIR ION SOURCE |
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Introduction. An inexpensive autosampler employing a 3' long, 1/4"-square aluminum bar riding on N-scale model railroad flat cars provides mass spectra obtained with a DART/TOFMS f...
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RELATIONSHIPS BETWEEN COMPOSITION AND PULMONARY TOXICITY OF PROTOTYPE PARTICLES FROM COAL COMBUSTION AND PYROLYSIS (MONTREAL, CANADA) |
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The hypothesis that health effects associated with coal combustion fly-ash particles are exacerbated by the simultaneous presence of iron and soot was tested through two sets of ex...
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RELATIONSHIPS BETWEEN LEVELS OF VOLATILE ORGANIC COMPOUNDS IN AIR AND BLOOD FROM THE GENERAL POPULATION |
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Background: The relationships between levels of volatile organic compounds (VOCs) in blood and air have not been well characterized in the general population where exposure concen...
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RELATIONSHIPS BETWEEN SEDIMENT PROFILE IMAGERY (SPI) AND ENVIRONMENTAL VARIABLES |
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Poster presentation at a scientific conference...
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RELATIVE POTENCY BASED ON HEPATIC ENZYME INDUCTION PREDICTS IMMUNOSUPPRESSIVE EFFECT OF A MIXTURE OF POLYCHLORINATED DIBENZO-P-DIOXINS (PCDDS), DIBENZOFURANS (PCDFS) AND BIPHENYLS (PCBS) |
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ABSTRACT
). Mixture (MIX)-1 contained TCDD , 2,3,7,8-tetrachlorodibenzofuran (TCDF), 1,2,3,7,8-pentachlorodibenzofuran (1-PeCDF), 2,3,4,7,8-pentachlorodibenzofuran (4-PeCDF), a...
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REMEDIATION OF TCE-CONTAMINATED GROUNDWATER BY A PERMEABLE REACTIVE BARRIER FILLED WITH PLANT MULCH (BIOWALL) |
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A pilot-scale permeable reactive barrier filled with plant mulch was installed at Altus Air Force Base (in Oklahoma, USA) to treat trichloroethylene (TCE) contamination in ground w...
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REMOVAL OF ADDED NITRATE IN THE SINGLE, BINARY, AND TERNARY SYSTEMS OF COTTON BURR COMPOST, ZEROVALENT IRON, AND SEDIMENT: IMPLICATIONS FOR GROUNDWATER NITRATE REMEDIATION USING PERMEABLE REACTIVE BARRIERS |
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Recent research has shown that carbonaceous solid materials and zerovalent iron (Fe0) may potentially be used as media in permeable reactive barriers (PRBs) to degrade groundwater ...
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REPEATED TREATMENTS WITH DOXORUBICIN CAUSES ELECTROCARDIOGRAM (ECG) CHANGES AND INCREASED VENTRICULAR PREMATURE BEATS IN WISTAR-KYOTO (WKY) RATS |
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Doxorubicin (DOX) is a widely used anthracycline anti-neoplastic drug used to treat tumors. However it has been implicated in irreversible cardiac toxicity via the generation of a ...
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RESEARCH ACTIVITIES AT U.S. GOVERNMENT AGENCIES IN SUBSURFACE REACTIVE TRANSPORT MODELING |
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The fate of contaminants in the environment is controlled by both chemical reactions and transport phenomena in the subsurface. Our ability to understand the significance of these...
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RESIDENTIAL EXPOSURE TO DRINKING WATER ARSENIC IN INNER MONGOLIA, CHINA |
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Residential exposure to drinking water arsenic in Inner Mongolia, China
Zhixiong Ning1, Richard K. Kwok2, Zhiyi Liu1, Shiying Zhang1, Chenglong Ma1, Danelle T. Lobdell2, Michael...
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RESOURCE MANAGERS BENEFIT FROM EPA'S VIEW OF THE OZARKS LANDSCAPE |
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The words “promise, praise, and problems” are frequently used to describe recent industry and population growth in the Ozark Mountains region (see, for example, Kirkpatrick, S. No ...
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RESUSPENDED SEDIMENTS CAN CONTRIBUTE TO THE ESTABLISHMENT AND MAINTENANCE OF HYPOXIA ON THE LOUISIANA CONTINENTAL SHELF |
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ABSTRACT FOR PRESENTATION...
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REVIEW IV: SCIENCE LINKING ENVIRONMENTAL CONTAMINANT EXPOSURES WITH FERTILITY AND REPRODUCTIVE HEALTH IMPACTS IN THE ADULT FEMALE |
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Design: Reviewed articles indexed in PubMed from 1999-2007 addressing environment and puberty, menstrual and ovarian function, fertility, and menopause.
Results: The strongest e...
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RNA Extraction Methods for Real-Time PCR and Microarray Analyses of Cryptosporidium and Toxoplasma gondii Oocysts - 2nd Presentation |
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The ability of infectious oocyst forms of Toxoplasma gondii and Cryptosporidium spp. to resist disinfection treatments and cause disease may have significant public health implicat...
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RNA Extraction Methods for Reverse Transcriptase Real-Time PCR and Microarray Analysis of Cryptosporidium and Toxoplasma gondii Oocysts |
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The ability of infectious oocyst forms of Toxoplasma gondii and Cryptosporidium spp. to resist disinfection treatments and cause disease may have significant public health implicat...
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ROLE OF TOXICS IN SEAGRASS DECLINES: A FLORIDA PERSPECTIVE. |
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Abstract
Original title: "FATE AND EFFECTS OF ANTHROPOGENIC CHEMICALS IN SEAGRASS ECOSYSTEMS."...
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Rain Garden Research at EPA’s Urban Watershed Research Facility |
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Summary of the ongoing rain garden research at UWMB. The context for the study was described as well as the experimental design for the full-scale study, instrumentation, and stor...
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Rain Garden Research at EPA’s Urban Watershed Research Facility: Promoting Nitrate Removal through Rain Garden Design |
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Rain gardens are designed to infiltrate stormwater, capture suspended solids, sorb heavy metals and phosphorus, and transform nutrients through biological processes. Most studies ...
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Rain Garden Research at NRMRL’s Urban Watershed Research Facility: Evaluating Pollutant Removal Performance |
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This slide was displayed on a TV screen along with slides from other ORD postdocs at the EPA Science Forum Postdoc Exhibit, May 20-22. The slide illustrated the rain garden resear...
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Reactive Fe/Pd Bimetallic Systems-Impregnated Adsorptive Activated Carbon For The Environmental Risk Management Of Contaminated Sites |
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Remediation of sediments and groundwater contaminated with hydrophobic organic chemicals such as polychlorinated biphenyls (PCBs) and polycyclic aromatic hydrocarbons remains a sci...
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Real-time combustion monitoring of PCDD/F indicators by REMPI-TOFMS |
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Analyses for polychlorinated dibenzodioxin and dibenzofuran (PCDD/F) emissions typically require a 4 h extractive sample taken on an annual or less frequent basis. This results in ...
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Recent Developments in Toxico-Cheminformatics: A New Frontier for Predictive Toxicology |
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Efforts to improve public access to chemical toxicity information resources, coupled with new high-throughput screening (HTS) data and efforts to systematize legacy toxicity studie...
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Recent Developments in Toxico-Cheminformatics; Supporting a New Paradigm for Predictive Toxicology |
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EPA's National Center for Computational Toxicology is building capabilities to support a new paradigm for toxicity screening and prediction through the harnessing of legacy toxicit...
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Recent Findings in EPA’s Lead Scavengers Evaluation |
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In response to continued concerns about the concentrations of 1,2-dibromoethane (EDB) in ground water from spills of leaded gasoline, OUST formed a Lead Scavengers Team with assist...
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Reconfiguration of water-energy systems for healthy and sustainable urban water management |
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Presentation at the the International Conference on Water Scarcity, Global, Changes, and Groundwater Management Responses...
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Recovery of a PCB-Contaminated Creek Fish Community |
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Polychlorinated Biphenyls (PCBs) from the Sangamo-Weston Superfund Site near Clemson, South Carolina, USA, were released into the Twelvemile Creek until the early 1990s. PCB concen...
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Rehabilitation of Wastewater Collection and Water Distribution Systems |
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The nation’s 54,000 drinking water systems and 16,000 wastewater systems are nearing the end of their useful life and need to be replaced/repaired to comply with federal regulation...
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Relationship Between Watershed Land Use and Denitrification Enzyme Activity in Headwater Streams |
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Headwater streams are the dominant land-water interface across much of the landscape. Denitrification is an important ecological service provided by headwater streams. Anthropogeni...
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Relationships between composition and pulmonary toxicity of prototype particles from coal combustion and pyrolysis |
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The hypothesis that health effects associated with coal combustion fly-ash particles are exacerbated by the simultaneous presence of iron and soot was tested through two sets of ex...
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Release Mechanisms, Control Strategies, and Implementation Challenges of Controlling Lead in Drinking Water |
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Even minimally or moderately corrosive water can cause unacceptable and dangerous lead contamination to be released from common plumbing materials and devices into drinking water. ...
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Remediation Evaluation Model for Chlorinated Solvents (REMChlor) |
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A new analytical solution has been developed for simulating the transient effects of groundwater source and plume remediation. This development was performed as part of a Strategi...
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Remote sensing: A tool for resistance monitoring in Bt crops |
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Corn forecasts anticipated significant increases in transgenic corn plantings in the United States for the 2007 growing season and foreseeable future. Driven by biofuel demand, si...
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Removal of EDB and 1,2-DCA by Abiotic Reaction with Iron (II) Sulfide |
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To properly evaluate the risk associated with exposure to EDB and 1,2-DCA in ground water from old spills of leaded gasoline, it is necessary to understand the mechanisms that may ...
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Repeating History: Pharmaceuticals in the Environment |
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As state-of-the-art analytical techniques become more sensitive and widely deployed, an increasing number of human and veterinary drugs are being detected in environmental samples....
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Representing Chemical-Induced Liver Injury for Multiscale Tissue Modeling |
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This presentation will provide an overview of the knowledgebased approach for representing MoA information in rodents and its extrapolation/translation to humans....
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Reproductive Development in a Multi-Generational Rat Bioassay of Drinking Water Concentrates in the Four Lab Study |
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To address concerns raised by epidemiological studies, we conducted a multigenerational reproductive toxicity study in rats using a “whole” mixture of drinking water disinfection b...
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Reproductive Toxicity of Vinclozolin in the Fathead Minnow: Confirming an Anti-androgenic Mode of Action |
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The objective of this study was to characterize responses of the reproductive endocrine system of the fathead minnow to the fungicide vinclozolin....
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Research to inform policy on headwater streams: ongoing and future directions |
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Headwater streams are the exterior links of stream networks and represent a substantial proportion of U.S. stream miles. Alteration and loss of headwater streams have occurred with...
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Research to inform policy on headwater streams: ongoing and future directions--oral presentation |
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Oral presentation at Southern Illinois University, Department of Zoology, Graduate Student Association Seminar...
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Resistance Management Monitoring For the US Corn Crop |
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Significant increases in genetically modified corn planting are expected for future planted acreages approaching 80% of total corn plantings anticipated by 2009. As demand increas...
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Resistance Management Research Status |
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Long-term sustainability of genetically modified corn expressing Bt relies on the validity of assumptions underlying IRM models used by the EPA and the ability of EPA to monitor, d...
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Resistance Management Research Status-May 2008 |
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Long-term sustainability of genetically modified corn expressing Bt relies on the validity of assumptions underlying IRM models used by the EPA and the ability of EPA to monitor, d...
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Resistance Management Research for PIP Crops |
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A significant increase in genetically modified corn planting driven by biofuel demand is expected for future planted acreages approaching 80% of total corn plantings in 2009. As d...
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Resolving Local-Scale Emissions for Modeling Air Quality near Roadways |
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A large body of literature published in recent years suggests increased health risk due to exposure of people to air pollution in close proximity to roadways. As a result, there i...
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Responsiveness of Great Lakes Wetland Indicators to Human Disturbances at Multiple Spatial Scales: A Multi-assemblage Assessment |
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Developing indicators of ecosystem condition is a priority in the Great Lakes, but little is known about appropriate spatial scales to characterize disturbance or response for most...
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Risk Reduction from Minimization of Persistent, Bioaccumulative, and Toxic Waste Materials Within the U.S. Industrial Solid Waste Management System |
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This study addressed three questions of interest in national-scale solid and hazardous waste management decision-making within the United States: 1) can we quantify the reduction ...
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Risk Reduction via Greener Synthesis of Noble Metal Nanostructures and Nanocomposites |
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A brief account of greener production of nanoparticles which reduces or eliminates the use and generation of hazardous substances is presented. The utility of vitamins B1 and B2, w...
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Risks to aquatic organisms posed by human pharmaceutical use |
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In order to help prioritize future research efforts within the US, risks associated with exposure to human prescription pharmaceutical residues in wastewater were estimated from ma...
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Robert S. Kerr Environmental Research Center |
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The Kerr Center, situated on 16 acres three miles south of Ada, Oklahoma, houses the Ground Water and Ecosystems Restoration Division (GWERD) of the National Risk Management Resear...
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Roles of Quantitative in vitro ADME in Toxicology and Risk or Safety Assessment |
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Describe uses if in vitro ADME, predicting in vivo pharmacokinetics, and combining ADME processes with in vitro assays for effects...
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SAMS #1: Using Fish Tissue Data to Monitor Remedy Effectiveness |
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This document provides general background and specific recommendations on how to design and implement fish monitoring programs for Superfund sites for the detection of significant ...
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SCIENTIFIC UNCERTAINTIES IN ATMOSPHERIC MERCURY MODELS III: BOUNDARY AND INITIAL CONDITIONS, MODEL GRID RESOLUTION, AND HG(II) REDUCTION MECHANISMS |
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In this study we investigate the CMAQ model response in terms of simulated mercury concentration and deposition to boundary/initial conditions (BC/IC), model grid resolution (12- v...
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SCOUT 2008 (WINDOWS VERSION 1.00.00) SOFTWARE PACKAGE, INCLUDING SCOUT 2008 (VERSION 1.00.00) USER GUIDE |
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The Scout 2008 version 1.0 software package provides a wide variety of classical and robust statistical methods that are not typically available in other commercial software packag...
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SEAGRASS DISTRIBUTION IN THE PENSACOLA BAY SYSTEM, NORTHWEST FLORIDA |
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Seagrass coverage in the northern Gulf of Mexico has decreased 20 to 100% in many estuaries since the 1950s. As a result, determination of seagrass coverage and identification of ...
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SEDIMENT METABOLISM ON THE LOUISIANA CONTINENTAL SHELF |
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Abstract for presentation...
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SEDIMENT TOXICITY IDENTIFCATION AND EVALUATION (TIE) PHASES I,II,III GUIDANCE DOCUMENT |
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Poster presentation at a scientific conference...
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SELDI PROTEINCHIP-BASED LIVER BIOMARKERS IN FUNGICIDE EXPOSED ZEBRAFISH |
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The research presented here is part of a three-phased small fish computational toxicology project using a combination of 1) whole organism endpoints, 2) genomic, proteomic, and met...
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SHIPBOARD PHOSPHORUS, NITROGEN AND SILICA NUTRIENT LIMITATION ASSAYS USING IN-VIVO PHYTOPAM FLUORESCENCE IN THE NORTHERN GULF OF MEXICO |
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ABSTRACT FOR PRESENTATION...
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SMARTe: A FREE Web-Based Tool To Help Communities Overcome Revitalization Obstacles - Detroit, MI, May 6, 2008 |
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SMARTe (Sustainable Management Approaches and Revitalization Tools - electronic) is a web-based decision support tool being developed by t...
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SODIUM BICARBONATE FACILITATES LOW-DOSE ORAL TOLERANCE TO PEANUT IN MICE |
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Rationale: Oral tolerance specifically inhibits production of allergic IgE antibody and is therefore a potential method for suppressing food allergy. We have previously demonstrate...
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SOT 2008- TRANSCRIPTIONAL RESPONSES IN THYROID TISSUES FROM RATS TREATED WITH A TUMORIGENIC AND A NON-TUMORIGENIC TRIAZOLE CONAZOLE FUNGICIDE |
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Conazoles are triazole- or imidazole-containing fungicides that are used in agriculture and medicine. Conazoles can induce follicular cell adenomas of the thyroid in rats after chr...
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SOURCES OF VARIATION IN BASELINE GENE EXPRESSION LEVELS FROM TOXICOGENOMIC STUDY CONTROL ANIMALS ACROSS MULTIPLE LABORATORIES |
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Variations in study design are typical for toxicogenomic studies, but their impact on gene expression in control animals has not been well characterized. A dataset of control anima...
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SPATIAL PATTERNS OF AIRBORNE PESTICIDES IN THE ALPINE HABITATE OF A DECLINING CALIFORNIA AMPHIBIAN, THE MOUNTAIN YELLOW-LEGGED FROG |
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The mountain yellow-legged frog complex (Rana muscosa complex) has disappeared from most of its historic localities in the Sierra Nevada of California, and airborne pesticides from...
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SPECIATION ANALYSIS OF ARSENIC IN BIOLOGICAL MATRICES BY AUTOMATED HYDRIDE GENERATION-CRYOTRAPPING-ATOMIC ABSORPTION SPECTROMETRY WITH MULTIPLE MICROFLAME QUARTZ TUBE ATOMIZER (MULTIATOMIZER) |
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Abstract Analyses of arsenic (As) species in tissues and body fluids of individuals chronically exposed to inorganic arsenic (iAs) provide essential information about the e...
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SPLICE VARIANT SPECIFIC UPREGULATIONOF CA+2/CALMODULIN DEPENDENT PROTEIN KINASE 1G BY PYRETHROID INSECTICIDES IN VIVO. |
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Pyrethroid insecticides induce neurotoxicity in mammals by interfering with ion channel function in excitable neuronal membranes. Previous work demonstrated dose-dependent increas...
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SSOAP - A USEPA TOOLBOX FOR SSO ANALYSIS AND CONTROL PLANNING |
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Rainfall Derived Infiltration and Inflow (RDII) into sanitary sewer systems has long been recognized as a source of operating problems in sewerage systems. RDII is the main cause o...
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STORMWATER TREATMENT USING MULTI-CHAMBERED TREATMENT TRAIN |
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slide presentation made at this conference.
MCTT developed to abate toxicants in stormwater from critical source areas
Pilot-scale reductions of > 90% for toxicity, Pb, Zn, ...
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STREAMWATER ACID-BASED CHEMISTRY AND CRITICAL LOADS OF ATMOSPHERIC SULFUR DEPOSITION IN SHENANDOAH NATIONAL PARK, VIRGINIA |
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A modeling study was conducted to evaluate the acid-base chemistry of streams within Shenandoah National Park, Virginia and to project future responses to sulfur (S) and nitrogen (...
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SUBCHRONIC EPISODIC EXPOSURE OF RATS TO DIESEL PLUS OZONE INDUCES MINIMAL CARDIOPULMONARY EFFECTS |
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Diesel exhaust (DE) emissions contribute to near-road air pollution and have been shown to induce a variety of cardiovascular and pulmonary abnormalities in animals and humans. Sin...
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SUBCHRONIC INHALATION OF ZINC SULFATE CAUSES CARDIAC CHANGES IN HEALTHY RATS |
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Zinc is a common metal in most ambient particulate matter (PM), and has been proposed to be a causative component in PM-induced adverse cardiovascular health effects. Zinc is also ...
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SUBCHRONIC TOXICITY OF INHALED TOLUENE IN RATS: OXIDATIVE STRESS MARKERS IN BRAIN. |
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The effects of long-term exposure to volatile organic compounds (VOCs), which is of concern to the EPA, are poorly understood, primarily due to insufficient information about human...
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SUMMARY REPORT OF AIR QUALITY MODELING RESEARCH ACTIVITIES FOR 2006 |
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Through a Memorandum of Understanding (MOU) and Memorandum of Agreement (MOA) between the Department of Commerce (DOC) and U.S. Environmental Protection Agency (EPA), the Atmospher...
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SUSTAIN - A BMP Process and Placement Tool for Urban Watersheds (Poster) |
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To assist stormwater management professionals in planning for best management practices (BMPs) and low-impact
developments (LIDs) implementation, USEPA is developing a decision su...
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SWALE RESEARCH AT NRMRL’S URBAN WATERSHED RESEARCH FACILITY |
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Swales are “engineered ditches” that provide stable routing for stormwater runoff. Swales are green infrastructure, a low-cost drainage option for highways, farms, industrial, and...
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SYMPOSIUM SESSION PROPOSAL: INCORPORATION OF MODE OF ACTION INTO MECHANISTICALLY-BASED QUANTITATIVE MODELS |
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The biological processes by which environmental pollutants induce adverse health effects is most likely regulated by complex interactions dependent upon the route of exposure, dose...
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SYNTHESIS AND ASSESSMENT PRODUCT 4.4: PRELIMINARY REVIEW OF ADAPTATION OPTIONS FOR CLIMATE SENSITIVE ECOSYSTEMS AND RESOURCES |
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This product will be a report produced under the auspices of the United States Climate Change Science Program (CCSP). The report is one of 21 synthesis and assessment products (SA...
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SYNTHESIS AND ASSESSMENT PRODUCT 4.6: ANALYSIS OF THE EFFECTS OF GLOBAL CHANGE ON HUMAN HEALTH AND WELFARE AND HUMAN SYSTEMS |
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This product is a report produced under the auspices of the United States Climate Change Science Program (CCSP). The report is one of the 21 synthesis and assessment products (SAP...
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Salmon 2100: Some recovery strategies that just might work |
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The primary goal of the Salmon 2100 Project is to identify practical options that have a high probability of maintaining biologically significant, sustainable populations of wild s...
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Scale Dependence in the Species-Discharge Relationship for Fishes of the Southeastern U.S.A. |
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Species-discharge relationships (SDR) are aquatic analogues of species-area relationships, and are increasingly used in both basic research and conservation planning. SDR studies ...
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Secondary Organic Aerosol Yields from Cloud-Processing of Isoprene Oxidation Products |
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Uncertainties in estimating aerosol direct and indirect effects on climate arise due to the complexity of aerosol properties and their source and sink processes. While these are u...
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Sediment Toxicity Identification and Evaluation (TIE) Phases I, II and III Guidance Document |
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This presentation summarizes the sediment toxicity identification evaluation (TIE) techniques that allow researchers to characterize and identify chemical causes of acute toxicity ...
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Selecting for resistance to the Cry3Bb1 protein in a genetically diverse population of non-diapausing Western Corn Rootworm |
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Abstract published in Resistant Pest Management Newsletter, a biannual newsletter of the Center for Integrated Plant Systems (CIPS) in cooperation with the Insecticide Resistance A...
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Selection for resistance to the Cry3Bb1 protein in a genetically diverse population of non-diapausing Western Corn Rootworm |
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The western corn rootworm (WCR, Diabrotica virgifera virgifera) is a serious economic pest of corn, and historically has evolved resistance to many chemical insecticides when used ...
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Selenium-Water Treatment Residual Adsorption And Characterization |
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Aluminum-based water treatment residuals (WTR) have the ability to adsorb tremendous quantities of soil-borne P, and have been shown to adsorb other anions, such as As (V), As (III...
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Semi-Analytical Models of CO2 Injection into Deep Saline Aquifers: Evaluation of the Area of Review and Leakage through Abandoned Wells |
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This presentation will provide a conceptual preview of an Area of Review (AoR) tool being developed by EPA’s Office of Research and Development that applies analytic and semi-analy...
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Sensivity of Adult Reproduction and Reproductive Development in Japanese Medaka Exposed to 4-Tert-octylphenol |
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In response to legislation, the USEPA is developing assessment tools for identifying chemicals likely to cause sublethal effects on reproduction and reproductive development with u...
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Short-term Dynamics and Retention of Triclosan in the Lower Hudson River Estuary |
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Triclosan (5-chloro-2-(2,4-dichlorophenoxy)-phenol) is a antimicrobial agent present in a wide array of consumer based goods such as soaps, skin creams and dental care products. T...
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Siletz River nutrients: Effects of biosolids application |
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Stream water nutrients were measured in the Siletz River, Oregon, with the goal of comparing dissolved nutrient concentrations, primarily the nitrogenous nutrients nitrate and ammo...
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Simple Approaches for Measuring Dry Atmospheric Nitrogen Deposition to Watersheds |
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Assessing the effects of atmospheric nitrogen (N) deposition on surface water quality requires accurate accounts of total N deposition (wet, dry, and cloud vapor); however, dry dep...
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Simulating Runoff from a Grid Based Mercury Model: Flow Comparisons |
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Several mercury cycling models, including general mass balance approaches, mixed-batch reactors in streams or lakes, or regional process-based models, exist to assess the ecologica...
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Simulating the Vapour Phase Air/Water Exchange of p,p′-DDE, p,p′-DDT, Lindane, and 2,3,7,8-Tetrachlorodibenzodioxin |
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Uncertainties in our understanding of gaseous air/water exchange have emerged as major sources of concern in efforts to construct global and regional mass balances of both the gree...
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Site Characterization for MNA of Radionuclides in Ground Water |
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Monitored natural attenuation is often evaluated as a component of the remedy for ground water contaminated with radionuclides. When properly employed, monitored natural attenuatio...
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Site Information Management: Visualizing and Making Decisions |
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Presentation at Tenth International Conference on Soil-Water Systems, June 2008....
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Skin sensitization in chemical risk assessment: Report of aWHO/IPCS international workshop focusing on dose–responseassessment |
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An international workshop was held in 2006 to evaluate experimental techniques for hazard identification and hazard characterization of sensitizing agents in terms of their ability...
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Slow-Releasing Oxygen Source |
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Subsurface pollution is an environmental issue of great concern in the United States and around the world. Bioremediation has proven to be an effective and environmentally prefera...
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Small-Scale Evaluation of the Expeditionary Unit Water Purifier |
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The U.S. EPA’s Technology Testing and Evaluation Program has been charged by EPA to evaluate the performance of commercially available water security-related technologies. Througho...
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Soil carbon sequestration: Quantifying this ecosystem service |
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Soils have a crucial role in supplying many goods and services that society depends upon on a daily basis. These include food and fiber production, water cleansing and supply, nut...
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Some Environmental Consequences of a Release of Ethanol to Ground Water |
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Estimates on the concentration of ethanol in ground water as a result of a spill of gasoline containing 10% to 15% ethanol vary from approximately 4,000 mg/L to 15,000 mg/L.
Pub...
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Sorption of PFOA and PFOS to Aquifer Sediment |
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During its years of operation, the Washington County Sanitary Landfill near St. Paul, Minnesota accepted both municipal and industrial solid waste. Several years of ground water mo...
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Sorption of PFOA and PFOS to Ground Water Sediment |
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During its years of operation, the Washington County Sanitary Landfill near St. Paul, Minnesota accepted both municipal and industrial solid waste. Several years of ground water mo...
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Southwest Region Threatened, Endangered, and At-Risk Species Workshop: Managing Within Highly Variable Environments Hydrology and Ecology of Intermittent Stream and Dry Wash Ecosystems |
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Ephemeral (dry washes) and intermittent streams make up approximately 59% of all streams in the U.S. (excluding Alaska), and over 81% in the arid and semi-arid Southwest (Arizona, ...
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Spatial Approaches for Ecological Screening and Exposure Assessment of Chemicals and Radionclides |
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This presentation details a tool, SADA, available for use in environmental assessments of chemicals that can also be used for radiological assessments of the environment. Spatial ...
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Spatial and Temporal Variability of Solar Ultraviolet Exposure of Coral Assemblages in the Florida Keys: Importance of Colored Dissolved Organic Matter |
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Solar UV radiation can have deleterious effects on coral assemblages in tropical and subtropical marine environments. We present evidence that UV exposure of coral reefs in the Flo...
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Spatial and Temporal Variability of Solar Ultraviolet Exposure of Coral Assemblages in the Florida Keys: Importance of Colored Dissolved Organic Matter x |
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Solar ultraviolet (UV) radiation can have deleterious effects on coral assemblages in tropical and subtropical marine environments, but little information is available on UV penetr...
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Spatial and functional characterization, identification and assessment of isolated wetlands in Alachua County, Florida, USA - GIS and remote sensing techniques |
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In this study, Geographic Information Systems (GIS) and remote sensing mapping techniques were developed to identify the locations of isolated wetlands in Alachua County, FL, a 251...
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Spatially- and Temporally-Resolved Measurements of Roadway Air Pollution Using a Zero-Emission Electric Vehicle |
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Vehicle-related air pollution has an intrinsically dynamic nature. Recent field measurements and modeling work have demonstrated that near-road topography may modify levels of air ...
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Speciation analysis of arsenic in biological matrices by automated hydride generation-cryotrapping-atomic absorption spectrometry with multiple microflame quartz tube atomizer (multiatomizer). |
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This paper describes an automated system for the oxidation state specific speciation of inorganic and methylated arsenicals by selective hydride generation - cryotrapping- gas chro...
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Speciation, Characterization, And Mobility Of As, Se, and Hg In Flue Gas Desulphurization Residues |
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Flue gas from coal combustion contains significant amounts of volatile elements, such as arsenic (As), selenium (Se) and mercury (Hg), which could lead to serious environmental hea...
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Spectroscopic and Photochemical Properties of Water-Soluble Fullerenol |
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Fullerenol, a hydroxylated form of C60-fullerene, is of potential environmental and biological significance due to its buckyball structure, hydroxyl groups and high water solubilit...
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Stormwater Retention Ponds and Constructed Wetlands Research at NRMRL’s Urban Watershed Research Facility |
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Microorganisms are priority stressors to receiving water bodies. Practitioners often consider structural stormwater management practices as effective tools to mitigate stormwater-...
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Strong population genetic structure and larval dispersal capability of the burrowing ghost shrimp (Neotrypaea californiensis) |
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The burrowing ghost shrimp, Neotrypaea californiensis, is a vital member of the estuarine benthic community. Dense populations of shrimp are found in the major estuaries of Washin...
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Sulfate-Reducing Bioreactors For The Treatment Of Acid Mine Drainage |
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Mine influenced water (MIW) affects a large portion of mountainous surface water bodies in the western United States as well as elsewhere. In this study, the purpose of this appli...
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Summary Report for the Workshop on Integrating Climate Change Adaption into Air Quality Decision Making |
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Over the past few decades, air quality planners have forecasted future air pollution levels based on information about changing emissions from stationary and mobile sources, popula...
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Supercritical Fluid Extraction of Aflatoxin B 1 from Soil |
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This research describes the development of a Supercritical Fluid Extraction (SFE) method to recover aflatoxin B1 from fortified soil. The effects of temperature, pressure, modifie...
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Susceptibility of the aging Brown Norway rat to carbaryl, an anti-cholinesterase-based insecticide: Thermoregulatory and cardiovascular responses. |
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The proportion of aged in the United States is projected to expand markedly for the next several decades. Hence, the U.S.EPA is assessing if the aged are more susceptible to enviro...
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Sustainability Metrics: The San Luis Basin Project |
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Sustainability is about promoting humanly desirable dynamic regimes of the environment. Metrics: ecological footprint, net regional product, exergy, emergy, and Fisher Information....
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Sustainable System Management with Fisher Information based Objectives |
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Sustainable ecosystem management that integrates ecological, economic and social perspectives is a complex task where simultaneous persistence of human and natural components of th...
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Sustainable Urban Waterfutures: A Vision |
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Background:
Urban growth is seriously limited by water scarcity on every continent, and trying to house more people that aspire to current developed region water services is s...
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Sustainable environmental nanotechnology using nanoparticle surface modification. |
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Reactive nanomaterials used for environmental remediation require surface modification to make them mobile in the subsurface. Nanomaterials released into the environment inadverte...
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Swine Fecal Metagenomics |
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Metagenomic approaches are providing rapid and more robust means to investigate the composition and functional genetic potential of complex microbial communities. In this study, we...
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Synthesis of Pd-N-heterocyclic carbene Pd-catalyst and its application in MW-assisted Heck and Suzuki reaction |
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The first Pd-N-heterocyclic carbene (NHC) complex in the form of organic silica is prepared using sol-gel method and its application in Heck and Suzuki reactions are demonstrated. ...
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TECHNICAL CHALLENGES ASSOCIATED WITH ASSESSING THE IN VITRO PULMONARY TOXICITY OF CARBON NANOTUBES |
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Nanotechnology continues to produce a large number of diverse engineered nanomaterials (NMs) with novel physicochemical properties for a variety of applications. Test methods that ...
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TECHNICAL CHALLENGES INVOLVED IN IMPLEMENTATION OF VOC REACTIVITY-BASED CONTROL OF OZONE |
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The control of VOC emissions based on their individual contribution to ozone formation has been the subject of intensive discussion and research in the past five years, and has gai...
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TEMPORAL AND SPATIAL VARIATION IN SOLAR RADIATION AND PHOTO-ENHANCED TOXICITY RISKS OF SPILLED OIL IN PRINCE WILLIAM SOUND, ALASKA |
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Solar irradiance (W/m2) and downwelling diffuse attenuation coefficients (Kd; m-1) were determined in several locations in Prince William Sound, Alaska, USA, between April 2003 and...
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TEMPORAL GEOPHYSICAL INVESTIGATIONS OF THE FT-2-PLUME AT THE WURTSMITH AIR FORCE BASE, OSCODA, MICHIGAN |
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The decommissioned Wurtsmith Air Force Base former Fire Training Cell (FT-02) facility has been the focus of several geophysical investigations. After several decades of fire train...
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TESTING AND ANALYSES OF CHAT AND ASPHALT-CONTAINING CHAT |
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Granular mine waste are generated from the extraction and beneficiation of lead/zinc minerals. The fine gravel waste, commonly known as chat, in the Tristate Mining District conta...
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TESTING AND ANALYSES OF CHAT AND ASPHALT-CONTAINING CHAT (PRESENTATION) |
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Granular mine waste are generated from the extraction and beneficiation of lead/zinc minerals. The fine gravel waste, commonly known as chat, in the Tristate Mining District conta...
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THE AORTA, BUT NOT LUNG OR HEART, IS THE TARGET OF SUBCHRONIC DIESEL-INDUCED INJURY AND INFLAMMATION |
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Recently cardiovascular abnormalities have been noted in individuals exposed to diesel exhaust (DE) or traffic generated air pollution; however, the mechanisms are unknown. We pos...
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THE APPLICATION OF BIOMONITORING DATA IN RISK ASSESSMENT: AN EXPANDED CASE-STUDY WITH BENZENE |
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Improved analytical methods permit the measurement of low levels of chemicals in human tissues. Despite evidence that chemicals are absorbed, it is unclear whether the relatively ...
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THE DEVELOPMENT OF A STANDARDIZED NEIGHBORHOOD DEPRIVATION INDEX FOR USE WITH REPRODUCTIVE OUTCOMES |
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Census data are widely used for assessing neighborhood socioeconomic context. Research using census data has been inconsistent in variable choice and usually limited to single geo...
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THE DISTRIBUTION OF COLORED DISSOLVED ORGANIC MATTER (CMOD)AND SALINITY ALONG THE SOUTHERN NEW ENGLAND COAST FROM AIRCRAFT REMOTE SENSING |
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Poster presentation at a scientific conference...
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THE DRINKING WATER TREATABILITY DATABASE (Slides) |
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The Drinking Water Treatability Database (TDB) assembles referenced data on the control of contaminants in drinking water, housed on an interactive, publicly-available, USEPA web s...
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THE EFFECTS OF ANTI-INFLAMMATORY IFNγ AND PRO-INFLAMMATORY TNFα, IL-1β ON CHEMOKINE RELEASE IN MOUSE EPITHELIAL CELLS |
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RATIONALE: Asthma is a chronic inflammatory disorder of the airways that affects nearly 20 million individuals in the US. Airway inflammation is a hallmark characteristic of asth...
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THE EFFECTS OF FUNCTIONALIZED AND NON-FUNCTIONALIZED CARBON NANOTUBES ON ROOT ELONGATION OF SELECTED CROP SPECIES |
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Single-walled carbon nanotubes (SWNT) have many potential beneficial uses with additional applications constantly being investigated. However, these unique properties create a pot...
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THE EMERGY BASIS FOR HUMAN SERVICE |
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Platform presentation at a scientific conference...
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THE IMPORTANCE OF CONCURRENT MONITORING AND MODELING FOR UNDERSTANDING MERCURY EXPOSURE IN THE ENVIRONMENT |
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Understanding the cycling processes governing mercury exposure in the environment requires sufficient process-based modeling and monitoring data. Monitoring provides ambient concen...
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THE INFLUENCE OF PARTICULATE AIR POLLUTANTS ON ALLERGIC SENSITIZATION IN ANIMAL MODELS |
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Air pollution has long been associated with detrimental health risks in susceptible populations including asthmatics. Experimental evidence in rodents indicates that inhaled or in...
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THE INFLUENCE OF SUBURBAN LAND USE ON HABITAT AND BIOTIC INTEGRITY OF COASTAL RHODE ISLAND STREAMS |
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Watershed land use in suburban areas can affect stream biota through degradation of instream habitat, water quality, and riparian vegetation. By monitoring stream biotic communitie...
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THE PHYSICAL AND CHEMICAL CHARACTERIZATION OF THE EMISSIONS FROM A RESIDENTIAL OIL BOILER |
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The toxicity of emissions from the combustion of home heating oil and the use of residential oil boilers (ROB) is an important health concern. Yet scant physical and chemical info...
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THE POWER TO DETECT A DIFFERENCE: DETERMINING SAMPLE SIZE REQUIREMENTS FOR EVALUATION OF REPRODUCTIVE/DEVELOPMENTAL EFFECTS FROM EXPOSURE TO COMPLEX MIXTURES OF DISINFECTION BYPRODUCTS |
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Toxicological assessment of environmentally-realistic complex mixtures of drinking-water disinfection byproducts (DBPs) are needed to address concerns raised by some epidemiologica...
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THE ROLE OF CATALYST PROPERTIES ON METHANOL OXIDATION OVER V2O5-TIO2 USING OZONE |
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Oxidation of methanol over V2O5 catalysts supported on anatase TiO2 that were prepared using sol-gel formation and impregnation procedures were inv...
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THE ROLE OF FLAVONOIDS IN MODULATION OF THE METABOLISM OF ARSENIC |
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The biotransformation of inorganic arsenic (iAs) in humans produces trivalent and pentavalent methylated species. The pattern and extent of iAs conversion is critical for the overa...
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THE ROLE OF PROTEIN BINDING OF TRIVALENT ARSENICALS IN ARSENIC CARCINOGENESIS AND TOXICITY |
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Three of the most plausible biological theories of arsenic carcinogenesis are protein binding, oxidative stress and altered DNA methylation. This review presents the role of trival...
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THE URINARY BLADDER EXHIBITS A U-SHAPED GENOMIC DOSE-RESPONSE FOLLOWING SHORT- AND LONG-TERM EXPOSURE OF MICE TO ARSENATE IN DRINKING WATER |
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A number of studies have demonstrated increased urinary bladder tumor incidence in populations exposed to inorganic arsenic in drinking water at concentrations on the order of seve...
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THE USE OF LANDSCAPE SCIENCE FOR THE ASSESSMENT OF ENVIROMENTAL SECURITY |
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The assessment of land use and land cover is an extremely important activity for contemporary land management. Human land-use practices (including type, magnitude, and distribution...
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THE USE OF MODIS NDVI DATA FOR CHARACTERIZING CROPLAND ACROSS THE GREAT LAKES BASIN |
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The Moderate Resolution Imaging Spectroradiometer (MODIS) provides new opportunities for characterizing land-cover (LC) to support monitoring and assessment studies at watershed, r...
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THE USE OF SCENARIO ANALYSIS TO ASSESS FUTURE LANDSCAPE CHANGE ON WATERSHED CONDITION IN THE PACIFIC NORTHWEST (USA) |
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The traditional definition of security has been broadened to include environmental threats resulting from resource degradation and scarcity related to anthropogenic development. Th...
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THe Pacific Northwest in 2010: An alternative futures perspective on salmon recovery |
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The primary goal of the Salmon 2100 Project is to identify practical options that have a high probability of maintaining biologically significant, sustainable populations of wild s...
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TIME COURSE OF THE TRANSCRIPTIONAL RESPONSE OF RAT CEREBROCORTICAL TISSUE AFTER ACUTE IN VIVO PYRETHROID EXPOSURE. |
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Pyrethroid insecticides disrupt neuronal function by interfering with the function of voltage-sensitive Na+ channels (VSSCs). Distinct differences in the pharmacological actions o...
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TISSUE DISTRIBUTION AND URINARY EXCRETION OF INORGANIC ARSENIC AND ITS METHYLATED METABOLITES IN C57BL/6 MICE FOLLOWING SUBCHRONIC EXPOSURE TO ARSENATE (ASV) IN DRINKING WATER |
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The relationship of exposure and tissue concentration of parent chemical and metabolites over prolonged exposure is a critical issue for chronic toxicities mediated by metabolite(s...
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TISSUE DISTRIBUTION OF ARSENIC SPECIES IN MICE CHRONICALLY EXPOSED TO METHYLARSONOUS ACID |
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The metabolism of inorganic arsenic (iAs) in humans yields toxic and carcinogenic methyl-As (MAs) and dimethyl-As (DMAs) intermediates. Methylarsonous acid (MAsIII) is the most acu...
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TISSUE DOSIMETRY, METABOLISM AND EXCRETION OF PENTAVALENT AND TRIVALENT DIMETHYLATED ARSENIC IN MICE AFTER ORAL ADMINISTRATION |
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Dimethylarsinic acid (DMA(V)) is a rat bladder carcinogen and the major urinary metabolite of inorganic arsenic in most mammals. This study examined the disposition of pentavalent...
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TRAFFIC AND METEOROLOGICAL IMPACTS ON NEAR-ROAD AIR QUALITY: SUMMARY OF METHODS AND TRENDS FROM THE RALEIGH NEAR-ROAD STUDY |
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There are adverse health effects in populations living, working or going to school near major roadways. A study was designed to assess traffic emissions impacts on air quality and...
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TRANSCRIPTIONAL RESPONSES IN THYROID TISSUES FROM RATS TREATED WITH A TUMORIGENIC AND A NON-TUMORIGENIC TRIAZOLE CONAZOLE FUNGICIDE |
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Conazoles are fungicides that are used in agriculture and medicine. Conazoles can induce follicular cell adenomas of the thyroid in rats after chronic bioassay and are considered t...
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TRANSCRIPTIONAL RESPONSES IN THYROID TISSUES FROM RATS TREATED WITH A TUMORIGENIC AND A NON-TUMORIGENIC TRIAZOLE CONAZOLE FUNGICIDE |
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What is the study?
Conazoles are triazole- or imidazole-containing fungicides that are used in agriculture and medicine. Conazoles can induce follicular cell adenomas of the ...
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TRANSFORMATION OF DEVELOPMENTAL NEUROTOXICITY DATA INTO STRUCTURE-SEARCHABLE TOXML DATABASE IN SUPPORT OF STRUCTURE-ACTIVITY RELATIONSHIP (SAR) WORKFLOW. |
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Early hazard identification of new chemicals is often difficult due to lack of data on the novel material for toxicity endpoints, including neurotoxicity. At present, there are no...
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TRICLOSAN ALTERS THYROID HORMONES HOMEOSTASIS VIA UP-REGULATION OF HEPATIC CATABOLISM. |
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Triclosan (5-chloro-2-(2,4-dichlorophenoxy)phenol) is a chlorinated phenolic antibacterial compound used in household and hygiene products. The structural similarity of triclosan t...
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TRICLOSAN AND ENDOCRINE DISRUPTION: EVIDENCE FOR ALTERATIONS IN THYROID HORMONE HOMEOSTASIS. |
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Impact Statement: Triclosan (5-chloro-2-(2,4-dichlorophenoxy)phenol) is a chlorinated phenolic antibacterial compound found as an active ingredient in many personal care and house...
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Temporal Trends of Triclosan in Sediment Cores Collected from Two Urbanized Estuaries |
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Triclosan (5-chloro-2-(2,4-dichlorophenoxy)-phenol) is a antimicrobial agent present in a wide array of consumer based goods such as soaps, skin creams and dental care products. I...
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Temporal Variation in the Estrogenicity of a Sewage Treatment Plant Effluent and its Biological Significance |
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This paper describes variations in the estrogenic potency of effluent from a "model" wastewater treatment plant in Duluth, MN, and explores the significance of these variations rel...
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Testing for Additivity in Chemical Mixtures Using a Fixed-Ratio Ray Design and Statistical Equivalence Testing Methods |
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Fixed-ratio ray designs have been used for detecting and characterizing interactions of large numbers of chemicals in combination. Single chemical dose-response data are used to pr...
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The Analysis of Genomic Dose-Response Data in the EPA ToxCast™ Program |
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The U.S. EPA must assess the potential adverse effects of thousands of chemicals, often with limited toxicity information. Accurate toxicity predictions will help prioritize chemic...
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The Androgen Trenbolone and the Anti-androgen Flutamide Regulate Distinct Biological Processes in Fathead Minnow |
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This presentation will describe how gene expression in the adult fathead minnow responds to short-term exposures to the model endocrine disrupting chemicals (EDCs)....
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The Construction And Instrumentation Of A Pilot Treatment System At The Standard Mine Superfund Site, Crested Butte, CO - (Presentation) |
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A pilot biochemical reactor (BCR) was designed and constructed to treat mine-influenced water emanating from an adit at a remote site in southern Colorado which receives an average...
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The Correlation of Secondary Organic Aerosol with Odd Oxygen in Mexico City |
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Data from a mountain location intercepting the Mexico City emission plume demonstrate a strong correlation between secondary organic aerosol and odd-oxygen (O3 + NO...
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The Drinking Water Treatability Database (Poster) |
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Drinking Water Treatability Database (TDB) will provide data taken from the literature on the control of contaminants in drinking water, and will be housed on an interactive, publi...
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The EPA ToxCast Program |
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There are tens of thousands of chemicals used in the environment for which little or no toxicology information is known. Current testing paradigms that use large numbers of animals...
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The Effect of Environmental Chemicals on Human Health -- CJA |
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Humans and animals have always been exposed to chemicals in our environment - natural products in foods, smoke from cooking fires, sewage in drinking water, pesticides from plants....
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The Effect of Lateral Boundary Values on Atmospheric Mercury Simulations with the CMAQ Model |
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Simulation results from three global-scale models of atmospheric mercury have been used to define three sets of initial condition and boundary condition (IC/BC) data for regional-s...
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The Enterococci qPCR Method for Recreational Water Quality Testing: Background and Single Lab Performance |
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Slide Presentation given at the Scientific Meeting on Development, Validation and Implementation of qPCR and PCR Methods for Use in Recreational Waters...
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The Evolution of Improved Baghouse Filter Media as Observed in the Environmental Technology Verification Program |
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The U.S. EPA implemented the Environmental Technology Verification (ETV) program in 1995 to generate independent and credible data on the performance of innovative technologies tha...
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The Healthy Men Study, a Partnership Exploring Associations between Drinking |
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Although the chlorination of public drinking water supplies has provided enormous public health benefits, toxicity test data regarding resultant disinfection by-products (DBPs) hav...
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The Impact of Chloride, Sulfate, and Bicarbonate on Iron Release from an Old Iron Pipe |
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“Colored water” describes the appearance of drinking water that contains suspended particulate iron where the actual suspension color may range from light yellow to red due to wate...
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The Impact of Satellite-derived Biomass Burning Emission Estimates on Air Quality |
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Various methods to generate satellite-based biomass burning emission estimates have recently been developed for their use in air quality models. Each method has different assumpti...
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The Importance of Exposure in Addressing Current and Emerging Air Quality Issues |
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The air quality issues that we face today and will face in the future are becoming increasingly more complex and require an improved understanding of human exposure to be effective...
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The Integrated Disinfection By-Product Mixtures Project (“4-Lab Study”): An Overview |
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The intended result of chemical disinfection of drinking water is reduction of microbial contamination and a concomitant decrease in waterborne disease. The formation of a myriad ...
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The Next Generation of Disinfection By-Products |
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The disinfection of drinking water has been rightly hailed as a public health triumph of the 20th century. Millions of people worldwide receive quality drinking water every day fro...
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The North American Mercury Model Intercomparison Study (NAMMIS). Study Description and Model-to-Model Comparison |
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This manuscript provides a description of the North American Mercury Model Intercomparison Study (NAMMIS) and results obtained from that study. The NAMMIS was conducted by EPA/NER...
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The Occurrence of Contaminant Accumulation in Lead Pipe Scales from Domestic Drinking Water Distribution Systems-ABSTRACT |
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Previous work has shown that contaminants such as Al, As and Ra, can accumulate in drinking water distribution system solids. The release of accumulated contaminants back into the ...
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The Performance of Adsorptive Media Full Scale Arsenic Removal Systems - USEPA Arsenic Demonstration Program |
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The presentation provides information and data on the performance of several full scale, arsenic removal adsorptive media treatment systems operated under the USEPA arsenic removal...
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The Power of Computer-aided Tomography to Investigate Marine Benthic Communities |
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Utilization of Computer-aided-Tomography (CT) technology is a powerful tool to investigate benthic communities in aquatic systems. In this presentation, we will attempt to summariz...
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The Reduction of Microbial and Chemical Contaminants with Selected POU/POE Systems |
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Centralized drinking water treatment and distribution alone may not always be the most practical or cost-effective option. Also, some consumers seeking a proactive measure to redu...
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The Response of Fish Habitat to Environmental Flows in the Albemarle-Pamlico Watershed |
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The provision of habitat for fish is an important service provided by rivers. Future land development and climate change will likely alter several aspects of habitat, including flo...
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The Role of Biofilms in Drinking Water Exposure to Potentially Pathogenic Legionella spp. |
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Legionellosis is a bacterial infection caused by species of the genera Legionella and is the most common waterborne disease reported in the United States. This type of infection ...
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The Role of Ecological Endpoints in Watershed Management |
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Landscape change and pollution in watersheds affect ecological endpoints in receiving water bodies. Therefore, these endpoints are useful in watershed management. Fish and benthic ...
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The Role of Exposure Science in Air Quality Management |
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Air quality standards and regulations are designed to protect public health and the environment. However, there are issues regarding whether the current standards and regulations ...
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The State of Coral Reef Ecosystems of the Florida Keys |
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Chapter 6 in NOAA Report, "The State of Coral Reef Ecosystems of the United States and Pacific Freely Associated States: 2008" covering the Florida Keys....
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The State of Coral Reef Ecosystems of the U.S. Virgin Islands. |
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Chapter in NOAA Report, "The State of Coral Reef Ecosystems of the United States and Pacific Freely Associated States: 2008" covering the U.S. Virgin Islands....
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The Toxicity Data Landscape for Environmental Chemicals |
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The Toxicity Data Landscape for Environmental Chemicals...
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The U.S.-German Bilateral Working Group (BGW): Collaborative Research For A Sustainable Future |
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Since 1990, the United States and Germany have worked bilaterally to identify, understand, and apply innovative technologies and policies for remediation and sustainable revitaliza...
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The US EPA's Endocrine Disruptor Screening Program: In VItro and In Vivo Mammalian Tier 1 Screening Assays |
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In response to emerging concerns that environmental chemicals may have adverse effects on human health by altering the function of the endocrine system, the Food Quality Protection...
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The Urban Stream Food Web: Synthesis of Recent Investigations and a Look Ahead |
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Research has repeatedly demonstrated declines in assemblage richness, diversity, and biotic integrity with increasing urbanization. Benthic macroinvertebrates are among the most wi...
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The Use of Aquatic Ecosystem Modeling in Environmental Management |
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Presentation on the use of aquatic ecosystem modeling in environmental management....
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The Variable Effects of Ozone and/or Diesel Particulate Inhalation Exposure on Allergic Airways Responses in Mice |
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Exposure to diesel exhaust particle matter (DEP) associated with the combustion of diesel fuel exacerbates asthma. Likewise, similar effects have been reported with exposure to the...
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The Virtual Embryo Project |
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The v-Embryo™ is a far reaching new research program at the US EPA to develop a working computer model of a mammalian embryo that can be used to better understand the prenatal risk...
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The Virtual Embryo Project (v-Embryo TM) |
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The v-Embryo is a far reaching new research program at the US EPA to develop a working computer model of a mammalian embryo that can be used to better understand the prenatal risks...
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The Virtual Liver Project: Modeling Tissue Response To Chemicals Through Multiscale Simulation |
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Discusses the newly developed US EPA, National Center for Computational Toxicology's Virtual Liver Project: Modeling Tissue Response To Chemicals Through Multiscale Simulation...
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The Virtual Liver Project: Modeling Tissue Response To Chemicals Through Multiscale Simulation |
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The US EPA Virtual Liver Project is aimed at simulating the risk of toxic effects from environmental chemicals in silico. The computational systems model of organ injury due to chr...
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The Virtual Liver Project: Simulating Tissue Injury Through Molecular and Cellular Processes |
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Efficiently and humanely testing the safety of thousands of environmental chemicals is a challenge. The US EPA Virtual Liver Project (v-Liver™) is aimed at simulating the effects o...
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The dark side of suibsidies: quantifying contaminant exposure to riparian predators via stream insects |
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Aquatic insects provide a critical nutrient subsidy to riparian food webs, yet their role as vectors of contaminants to terrestrial ecosystems is poorly understood. We investigated...
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The effect of diesel (DE) exposure in utero on reproductive and developmental immunotoxicity |
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Epidemiology studies are beginning to show that in utero exposure to traffic related pollutants might increase the incidence of immune mediated lung diseases. Time pregnant...
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The healthy men study: an evaluation of exposure to disinfection by-products in tap water and sperm quality |
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BACKGROUND: Chlorination of drinking water generates disinfection by-products (DBPs), which have been shown to disrupt spermatogenesis in rodents at high doses, suggesting that DBP...
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The healthy men study: design and recruitment considerations for environmental epidemiologic studies in male reproductive health |
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Study Objective: To describe study conduct and response and participant characteristics.
Design: Prospective cohort study.
Setting: Participants were male partners of wome...
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The influence of road salts on water quality in a restored urban stream (Columbus, OH) |
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Understanding the connection between road salts and water quality is essential to assess the implications for human health and ecosystem services. To assess the effects of the res...
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The need for a paradigm shift in toxicology xx. |
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This manuscript briefly reviews the impact of the NAS report “Toxicity Testing in the 21st Century: A Vision and A Strategy” and it’s potential impact on the field of toxi...
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The role of trans-disciplinary skills in environmental education and science |
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In the past three decades there have been tremendous changes in how environmental scientists address issues relating to societal needs. In the early 1980s interdisciplinary work m...
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The role of trans-disciplinary skills in environmental education and science - 5/2008 |
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In the past four decades there have been tremendous changes in how environmental scientists address issues relating to societal needs. In the early 1980s, interdisciplinary work i...
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The startle response and toxicology: Methods, use and interpretation. |
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The startle response (SR) is a sensory-evoked motor reflex that has been used successfully in toxicology for decades. Advantages of this procedure include: rapidly objective measur...
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Thermal Extraction–Two-Dimensional Gas Chromatography–Mass Spectrometry with Heart-Cutting for Nitrogen Heterocyclics in Biomass Burning Aerosols |
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A thermal extraction-two-dimensional gas chromatography-mass spectrometry (TE-GC-MS) method (with heart-cutting) is developed for quantitatively assessing nitrogen (N-bearing organ...
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Timing and Prediction of Climate Change and Hydrological Impacts: Periodicity in Natural Variations |
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Hydrological impacts from climate change are of principal interest to water resource policy-makers and practicing engineers, and predictive climatic models have been extensively in...
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Tissue Distribution and Metabolism of Benzo[a]pyrene in Embryonic and Larval Medaka Oryzias Latipes |
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This study emphasizes the importance of understanding metabolism of bioaccumulative chemicals and the relative toxicity of parent chemical and metabolites during different life sta...
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Tolerance to anatoxin-a and nicotine on operant behavior: A search for mechanisms. |
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Anatoxin-a is a cyanobacterial toxin of concern to EPA as it can contaminate water supplies and poison a wide variety of species by stimulating nicotinic receptors. Research has sh...
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Tools and Metrics for Environmental Sustainability |
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Within the U.S. Environmental Protection Agency’s Office of Research and Development the National Risk Management Research Laboratory has been developing tools to help design and e...
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Tools for Assessing Ecological Nanomaterial Exposures |
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Manufactured nanomaterials (MNs) are commonly defined as being
commercial products with at least one dimension in the size range of 1
nm to 100 nm that also possess unique prop...
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Tools for the Reduction and Assessment of Chemical and other Environmental Impacts (TRACI) use within Sustainability Systems |
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Describing TRACI and its relationshiop to NIST's BEES and the US GBC's LEED 2009...
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Toward a US National Air Quality Forecast Capability: Current and Planned Capabilities |
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As mandated by Congress, NOAA is establishing a US national air quality forecast capability. This capability is being built with EPA, to provide air quality forecast information w...
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Towards a joint national and state partnership in aquatic resource assessment monitoring survey design |
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The USEPA is currently conducting national assessments of all aquatic resources in the United States. Prior national assessments were completed for coastal waters and wadeable str...
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ToxCast: Developing Predictive Signatures of Chemically Induced Toxicity (S) |
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ToxCast, the United States Environmental Protection Agency’s chemical prioritization research program, is developing methods for utilizing computational chemistry, bioactivity prof...
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ToxCast: EPAs Contribution to the Tox21 Consortium |
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The international community needs better predictive tools for assessing the hazards and risks of chemicals. It is technically feasible to collect bioactivity data on virtually all...
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ToxCast: One Step in the NRC Vision of 21st Century Toxicology |
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The international community needs better predictive tools for assessing the hazards and risks of chemicals. It is technically feasible to collect bioactivity data on virtually all...
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ToxCast: One Step in the NRC Vision of 21st Century Toxicology (S) |
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The international community needs better predictive tools for assessing the hazards and risks of chemicals. It is technically feasible to collect bioactivity data on virtually all...
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ToxCast: One Step in the NRC Vision of 21st Century Toxicology (T) |
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The international community needs better predictive tools for assessing the hazards and risks of chemicals. It is technically feasible to collect bioactivity data on virtually all...
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ToxPredictor: a Toxicity Estimation Software Tool |
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The Computational Toxicology Team within the National Risk Management Research Laboratory has developed a software tool that will allow the user to estimate the toxicity for a vari...
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Toxicity Assessment of 17 alpha-ethinylestradiol by Cell-Culture Based NMR Metabolomics |
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A zebrafish liver cell line (ZFL) established from adult zebrafish has been used in a variety of biological research, including toxicology, pharmacology, developmental biology and ...
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Toxicity Data Informatics: Supporting a New Paradigm for Toxicity Prediction |
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Toxicity Data Informatics: Supporting a New Paradigm for Toxicity Prediction...
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Toxicity Equivalency Values for Polychlorinated Biphenyl Mixtures |
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This document determines dioxin toxicity equivalency factors for commercial PCB mixtures, e.g., Aroclors, Clophens, Kanechlors, Sovol, Delors, Phenoclor, and Chlorofen....
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Toxico-Cheminformatics: A New Frontier for Predictive Toxicology |
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The DSSTox database network and efforts to improve public access to chemical toxicity information resources, coupled with high-throughput screening (HTS) data and efforts to system...
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Toxicogenomic Dissection of the Perfluorooctanoic Acid Transcript Profile in Mouse Liver: Evidence for Involvement of the Nuclear Receptors PPARα and CAR |
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A number of perfluorinated alkyl acids including perfluorooctanoic acid (PFOA) elicit effects similar to peroxisome proliferator chemicals (PPC) in mouse and rat liver. There is st...
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Toxicogenomic Dissection of the Perfluorooctanoic Acid Transcript Profile in Mouse Liver: Evidence for the Involvement of Nuclear Receptors PPARα and CAR |
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A number of perfluorinated alkyl acids including perfluorooctanoic acid (PFOA) elicit effects similar to peroxisome proliferator chemicals (PPC) in mouse and rat liver. There is s...
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Toxicokinetics in Fishes |
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Chapter 3 in the book, "The Toxicology of Fishes". Richard T. Di Giulio and David E. Hinton, editors. CRC, Boca Raton,FL. 2008 ...
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Toxicology and senescence: Baseline variability and toluene effects on the motor function of aging brown Norway rats. |
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The rapidly expanding population of older adults raises concern in EPA over aging-related vulnerability to environmental exposures. Deficits in motor function are frequent with adv...
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Toxicoproteomics and its applications to human health risk assessment |
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What is the study?
Toxicoproteomics is the use of proteomic technologies to better understand environmental and genetic factors, toxic mechanisms and modes of action in response t...
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Tracking contaminant flux from aquatic to terrestrial food webs |
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Aquatic insects provide a critical energy subsidy to riparian food webs, yet their role as vectors of contaminants to terrestrial ecosystems is poorly understood. We investigated ...
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Tracking the pathway of arsenic metabolism |
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Although the toxic and carcinogenic properties of arsenic have been recognized for centuries, only in the past few decades has research focused on understanding the metabolic fate ...
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Trading forest carbon |
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The nature of carbon in forests is discussed from the perspective of carbon trading. Carbon inventories, specifically in the area of land use and forestry are reviewed for the Paci...
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Transformation of Reactive Iron Minerals in a Permeable Reactive Barrier (Biowall) Used to Treat TCE in Groundwater |
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Abstract: Iron and sulfur reducing conditions are generally created in permeable reactive barrier (PRB) systems constructed for groundwater treatment, which usually leads to format...
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Transient hypoxia stimulates mitochondrial biogenesis in brain subcortex by a neuronal nitric oxide synthase-dependent mechanism |
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The adaptive mechanisms that protect brain metabolism during and after hypoxia, for instance, during hypoxic preconditioning, are coordinated in part by nitric oxide (NO). We teste...
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Treasures in Archived Histolopathology Collections: Preserving the Past for Future Understanding |
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Extensive collections of histopathology materials from studies of marine and freshwater mollusks, crustaceans, echinoderms, and other organisms are archived in the Registry of Tu...
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Treasures in Archived Histopathology Collections: Preserving the Past for Future Understanding (NACSETAC) |
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Extensive collections of histopathology materials from studies of marine and freshwater mollusks, crustaceans, echinoderms, and other organisms are archived in the Registry of Tu...
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U.S. EPA High-Field NMR Facility with Remote Accessibility |
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EPA’s High-Field Nuclear Magnetic Resonance Research Facility housed in Athens, GA has two Varian 600 MHz NMR spectrometers used for conducting sophisticated experiments in environ...
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U.S. EPA's Ecosystem Services Research for Coastal Wetlands |
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Slide presentation on the EPA's ecosystem services research for coastal wetlands, NATO CCMS meeting in Dalaman, Turkey, October 2008....
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U.S. EPA's Watershed Management Research Activities |
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Watershed and stormwater managers need modeling tools to evaluate alternative plans for environmental quality restoration and protection needs in urban and developing areas. A wate...
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U.S. Environmental Technology Verification Program |
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Overview of the U.S. Environmental Technology Verification Program (ETV), the ETV Greenhouse Gas Technology Center, and energy-related ETV projects. Presented at the Department ...
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U.S. Environmental Technology Verification Program (ETV) |
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ETV is a partnership program that verifies the performance of innovative environmental technologies using stakeholder-developed protocols....
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US ENVIRONMENTAL PROTECTION AGENCY - FUTURE USE OF GOES-R IN AIR QUALITY ASSESSMENTS (INVITED TALK) |
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There is no abstract available for this product. If further information is requested, please refer to the bibliographic citation and contact the person listed under Contact Field....
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US LAND-COVER MONITORING AND DETECTION OF CHANGES IN SCALE AND CONTEXT OF FOREST |
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Disparate land-cover mapping programs, previously focused solely on mission-oriented goals, have organized themselves as the Multi-Resolution Land Characteristics (MRLC) Consortium...
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US-German Cooperation For Further Development Of Decision Support Systems For Sustainable Contaminated Site Revitalization - Berlin, Germany, Sept. 24, 2008. |
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SMARTe (Sustainable Management Approaches and Revitalization Tools - electronic) is a web-based decision support tool developed by the Off...
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USE OF PHYSIOLOGICALLY-BASED PHARMACOKINETIC (PBPK) MODELING AND TOXICOKINETICS/TOXICODYNAMICS (TK/TD) FOR SENSITIVE POPULATIONS AND LIFESTAGES. |
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Populations and lifestages may have differential sensitivity due to a combination of differences in exposure, how the body handles the chemical (toxicokinetics)and how the body res...
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USE OF PROBABILITY BASED SAMPLING OF WATER QUALITY INDICATORS IN SUPPORTING WATER QUALITY CRITERIA DEVELOPMENT |
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We propose that water quality indicator data collected from large scale, probability based assessments of coastal condition such as the US EPA National Coastal Condition Report III...
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USE OF RADIO FREQUENCY IDENTIFICATION (RFID) FOR TRACKING HAZARDOUS WASTE SHIPMENTS ACROSS INTERNATIONAL BORDERS - TEST/QA PLAN |
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The Environmental Technology Verification (ETV) – Environmental and
Sustainable Technology Evaluations (ESTE) Program conducts third-party verification testing of commercially ava...
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USE OF REPEATED BRONCHOALVEOLAR LAVAGE IN RABBITS TO ASSESS POLLUTANT-INDUCED LUNG CHANGES IN AN ANIMAL MODEL OF CARDIOVASCULAR (CV) DISEASE. |
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Animal models of coronary heart disease (e.g., hyperlipidemic rabbits) are being used to investigate epidemiologic associations between higher levels of air pollution and adverse C...
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USE OF WEIBULL FUNCTION FOR NON-LINEAR ANALYSIS OF EFFECTS OF LOW LEVELS OF SIMULATED HERBICIDE DRIFT ON PLANTS |
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We compared two regression models, which are based on the Weibull and probit functions, for the analysis of pesticide toxicity data from laboratory studies on Illinois crop and na...
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USEPA Arsenic Demonstration Program |
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The presentation provides background information on the USEPA arsenic removal program. The summary includes information on the history of the program, sites and technology selecte...
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USEPA Resistance Management Research |
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A significant increase in genetically modified corn planting driven by biofuel demand is expected for future planted acreages approaching 80% of total corn plantings in 2009. As d...
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USING CHIRALITY TO INFORM THE METABOLISM OF TRIADIMEFON TO TRIADIMENOL: A CROSS-SPECIES EXAMINATION |
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Triadimefon is a systemic agricultural fungicide of the conazole class whose metabolite, triadimenol, provides the majority of the actual fungicidal activity; i.e. inhibition of st...
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USING PHARMACOKINETIC DATA TO INTERPRET METABOLOMIC CHANGES IN CD-1 MICE TREATED WITH TRIAZOLE FUNGICIDES |
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Triazoles are a class of fungicides widely used in both pharmaceutical and agricultural applications. These compounds elicit a variety of toxic effects including disruption of norm...
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USING THE TARGET LIPID MODEL AS AN APPROACH TO ASSESS TISSUE RESIDUES AND THE RESPONSE OF ACUTE BASELINE TOXICANTS IN AQUATIC SPECIES. |
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Abstract for presentation....
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Uncertainty and variability in physiologically-based pharmacokinetic (PBPK) models: Key issues and case studies (Final Report) |
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This report summarizes some of the recent progress in characterizing uncertainty and variability in physiologically-based pharmacokinetic models and their predictions for use in ri...
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Understanding Genetic Toxicity Through Data Mining: The Process of Building Knowledge by Integrating Multiple Genetic Toxicity Databases |
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This paper demonstrates the usefulness of representing a chemical by its structural features and the use of these features to profile a battery of tests rather than relying on a si...
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Understanding Mechanisms Toxicity: Insights from Drug Discovery Research |
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This review describes the application of high-throughput screening assays as experimental tools for profiling chemicals for potential toxicity and understanding underlying mechanis...
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Unregulated DBPs of Potential Concern |
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The slides describe a few classes of unregulated disinfection byproducts (DBPs). They show some general chemical structures of those thus far identified in finished waters and pre...
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Update on PEC Activities and Introduction of Website and Improved Application Process |
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Over the last several years, there has been a growing interest in using alternative technologies for disinfection of municipal sludge destined for land application. The 503 regulat...
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Update on the Mammalian Tier 1 Endocrine Disruptor Screening Protocols |
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The endocrine system provides a number of target sites that may be susceptible to disruption by environmental agents. In response to emerging concerns that environmental chemicals...
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Update on the Status of Sanitary Sewer Overflow Analysis and Planning (SSOAP) Toolbox |
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A properly designed, operated and maintained sanitary sewer system is meant to collect and convey all of the sewage that flows into it to a wastewater treatment plant. However, occ...
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Urban Marine Habitat Use by Waterbirds in Narragansett Bay |
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We examined patterns of habitat use by waterbirds (waterfowl, shorebirds, and wading birds) at a series of urban and non-urban marine habitats in Narragansett Bay during 2005-2007....
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Urban Stormwater Stressors, Sources & BMPS |
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This paper covers the origin and values of the various pollutants or stressors in urban stormwater including flow (shear force), pathogens, suspended solids/sediment, toxicants (or...
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Urbanization eliminates ephemeral and intermittent stream length and increases perennial flow |
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Protection of headwater streams under the Clean Water Act has been under scrutiny in recent Supreme Court cases, leading to renewed interest in the extent of non-perennial tributar...
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Use Of Genomics In Chemical Mode Of Action Analysis |
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The US-EPA has spent considerable effort in the last few years to develop guidance on the use of genomics to inform the process for determining effects on humans and ecological spe...
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Use of (1-3)-β-D-glucan Concentrations in Dust as a Surrogate Method for Estimating Specific Mold Exposures |
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Indoor exposure to fungi has been associated with respiratory symptoms, often attributed to their major cell wall component, (1-3)-β-D-glucan (DG). This and the ease and low cost o...
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Use of On-line Microdialysis Sampling to Determine the In Vivo Rate of Phenol Glucuronidation in Rainbow Trout |
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A quantitative microdialysis (MD) sampling method was used to study phenol (PH) glucuronidation in vivo in rainbow trout. The method employs internal calibrators to account for cha...
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Use of Spectral Vegetation Indices for Detection of European Corn Borer Infestation in Iowa Corn Plots |
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Recently, corn grown for grain in the United States has increased from 28 million ha in 2006 to more than 35 million ha in 2007 with a production value of over $52 billion dollars....
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Use of a Ferrous Sulfate - Sodium Dithionite Blend to Treat a Dissolved Phase Cr(VI) Plume |
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A field study was conducted to evaluate the use of a combination of sodium dithionite and ferrous sulfate in creating an in situ redox zone for treatment of a dissolved phase Cr(VI...
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Use of electrostatic dust cloth for self-administered home allergen collection |
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Abstract Most epidemiologic studies employ a vacuum cleaner used by a trained technician to collect household allergens. This approach is labor intensive, equipment dependent, and ...
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Use of geospatial data to predict downstream influence of coal mining in Appalachia |
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A 2001 Supreme Court decision first called into question whether some headwater streams could be considered jurisdictional under the Clean Water Act. A subsequent decision then re...
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Use of probability based sampling of water quality indicators in supporting water quality criteria development - 2/28/08 |
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We examine the proposition that water quality indicator data collected from large scale, probability based assessments of coastal condition such as the US Environmental Protection ...
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Using Asymmetric Flow Field-Flow Fractionation (AF4) to Determine C60 Colloidal Size Distributions |
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The formation of aqueous fullerene suspensions by solvent exchange, sonication, or extended mixing in water is widely reported. Commonly used methods for determining the size of th...
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Using Attributes of Natural Systems to Plan the Built Environment |
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The concept of 'protection' is possible only before something is lost, however, development of the built environment to meet human needs also compromises the environmental systems ...
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Using Nanomaterials In Risk Management Of Environmental Pollutants: An Overview Of Recent Advancements |
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Persistent organic pollutants, known as POPs, are toxic substances released into the environment by human activities. Of all POPs released into the environment by human activity, ...
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Using Streamflow as a Predictor of Biotic Health in the Upper Oconee Watershed |
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Macroinvertebrates are commonly used as biological indicators of stream habitat and water quality. Chronic reduced streamflows can have a significant impact on biota, decreasing in...
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Using Web-Based Tools for Teaching Embryology |
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Computers, imaging technologies, and the worldwide web have assumed an important role in augmenting traditional learning. Resources to disseminate multimedia information across pl...
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Using a Metabolic Null Model to Predict Freshwater Fish Abundances at Regional to National Scales |
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Poster presented at the Conference on Aquatic Conservation Science held in Athens, GA, October 3-4, 2008....
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Using attributable risk to assess the regional-scale impacts of environmental stressors |
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We describe the application of population attributable risk (AR) for assessing the relative importance of aquatic stressors across large regions. A stressor's importance depends on...
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Using intensive indicators of wetland condition to evaluate a rapid assessment methodology in Oregon tidal wetlands |
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In 2011, the US EPA and its partners will conduct the first-ever national survey on the condition of the Nation’s wetlands. This survey will utilize a three-tiered assessment appr...
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Using stable isotopes and models to explore estuarine linkages at multiple scales |
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Estuarine managers need tools to respond to dynamic stressors that occur in three linked environments – coastal ocean, estuaries and watersheds. Models have been the tool of choic...
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VARIABILITY OF THE DIFFUSE DOWNDWELLING IRRADIANCE IN GULF OF MEXICO HYPOXIC AND NON-HYPOXIC WATERS |
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Abstract for presentation...
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VOLATILE POLAR METABOLITES IN EXHALED BREATH CONDENSATE (EBC): COLLECTION AND ANALYSIS |
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Environmental exposures, individual activities, and disease states can perturb normal metabolic processes and be expressed as a change in the patterns of polar volatile organic com...
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Vacuum Flushing of Sewer Solids (Slides) |
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The vacuum sewer and tank cleaning (flushing) technology removes sewer solids from urban drainage systems, such as storage tanks and pipes. This technology is both effective and in...
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Vaporization or Chemical Reaction: Which controls the fate of contaminants treated by in situ thermal remediation? |
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Thermal remediation technologies, which includes steam enhanced extraction, electrical resistance heating, and thermal conductive heating, have been developed based on technologies...
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Variation in pollen competitive ability in diverse maize lines |
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Although pollen occupies a small fraction of the angiosperm life cycle, it is of interest for both basic and applied scientific reasons. Seed production depends on a functional ma...
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Variations in High-Intensity Precipitation under Climate Changes in the LMRB and Implications on Drinking Water Supply Security |
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A systematic temporal and spatial analysis is being conducted at the U.S. EPA on historical precipitation and stream flow over the continental U.S. and their relationships with Atl...
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Verification of Cryptospporidium Removal by a Full-scale Water Treatment Plant Using a Yeast Challenge and Ramifications for Risk Assessments |
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Presentation at the Greater Cincinnati Water Works Advisory Commmittee, Cincinnati, September 26, 2008...
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Vertical Profiling of Soil Vapor Concentrations Using a New Passive Diffusion Sampler at a UST Site |
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Understanding the transport of volatile contaminants in soil gas, particularly those associated with underground storage tanks (USTs), requires a detailed knowledge about the depth...
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Virtual Beach Manager Toolset |
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The Virtual Beach Manager Toolset (VB) is a set of decision support software tools developed to help local beach managers make decisions as to when beaches should be closed due to ...
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Virtual Beach: Decision Support Tools for Beach Pathogen Prediction |
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The Virtual Beach Managers Tool (VB) is decision-making software developed to help local beach managers make decisions as to when beaches should be closed due to predicted high lev...
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Visible Light-activated TiO2 photocatalytic Films; Synthesis, Characterization and Environmental Application for the Destruction of Microcystin-LR |
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Titanium dioxide (TiO2) photocatalysis has become one of the most effective advanced oxidation technologies (AOTs) for the treatment of persistent organic contaminants. To generate...
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WATER QUALITY IN GREAT LAKES COASTAL WETLANDS: BASIN-WIDE PATTERNS AND RESPONSES TO AN ANTHROPOGENIC DISTURBANCE GRADIENT |
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This manuscript presents water quality data collected from wetlands around the U.S. shoreline of the Great Lakes, as part of a larger effort examining relationships between wetland...
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WATERSHED MANAGEMENT AND ARCGIS: THE RELEASE OF AGWA 2.0 |
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Focusing time, energy, and money where it can be best utilized is in the best interest of managers
everywhere. By making tools more widely available that facilitate the iden...
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WED Research Update Spring 2008 |
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Synopsis of research at the Western Ecology Division....
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Water Resources Adaptation to Global Changes: Risk Management through Sustainable Infrastructure Planning and Managements |
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Global changes due to cyclic and long-term climatic variations, demographic changes and economic development, have impacts on the quality and quantity of potable and irrigation sou...
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Water, Water Everywhere, But is it Safe to Drink? |
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Drinking water disinfection by-products (DBPs) have been associated with adverse human health effects, including bladder cancer, early term miscarriage, and birth defects. While i...
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Watershed Central: An Integrated Watershed Assessment and Management Website (Columbus, OH workshop). |
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The U.S.EPA’s Office of Water (OW), Office of Research and Development (ORD), and Office of Environmental Information (OEI) have teamed together with other Federal Agencies, state ...
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Watershed Central: An Integrated Watershed Assessment and Management Website (MO presentation) |
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The U.S. EPA’s Office of Water (OW), Office of Research and Development (ORD), and Office of Environmental Information (OEI) have teamed together with other Federal Agencies, state...
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Watershed Management in the United States |
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A watershed approach provides an effective framework for dealing with water resources challenges. Watersheds provide drinking water, recreation, and ecological habitat, as well as ...
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Watershed Nitrogen Modeling: Benefits of Diverse Approaches Using a Case Study from New York State |
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Watershed-scale models have evolved as an important tool for estimating the sources, transformation, and transport of contaminants to surface water systems. A wide variety of mode...
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What does it take to Demonstrate a Clear and Meaningful Trend for MNA? - Atlanta, GA |
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As specified in the 1999 OSWER Directive on MNA, the first line of evidence for MNA is historical data that demonstrate a clean and meaningful trend of decreasing concentration ove...
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What is the minimum number of sites needed for precisely assessing the ecological status of mainstem rivers? |
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We evaluated the number of sites that would yield relatively precise estimates of physical, chemical, and biological condition for six raftable rivers 100-200 km long and 20-120 m ...
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White Paper: Summary of the NOAA Workshop - Ecological Effect of Sea Level Rise in the Florida Panhandle and Coastal Alabama: Research and Modeling Needs |
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The Center for Sponsored Coastal Ocean Research (CSCOR) is addressing current and future impacts to ecological systems due to the long term effect of sea level rise due to climate ...
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Why Does the Environmental Protection Agency Study Toxicology and What Are Biological Models |
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An informal talk to high school students participating in the EPA/Shaw University Research Apprenticeship Program....
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Wild salmon in California, Oregon, Washington, and Idaho: Some recovery strategies that just might work |
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The primary goal of the Salmon 2100 Project is to identify salmon recovery options that have a high probability of maintaining biologically significant, sustainable populations of ...
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Workshop Report: Use of In Vitro Absorption, Distribution, Metabolism and Excretion (ADME) Data in Bioaccumulation Assesments for Fish |
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This manuscript describes the results of scientific workshop which was held March 2006, in San Diego, California. Workshop participants reviewed the state-of-the-science regarding...
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Workshop on Monitored Natural Attenuation for Inorganic Contaminants: 1 – Introduction, MNA Processes and Characterization |
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The purpose of this training is to present an overview of site characterization approaches to support evaluation of the potential for Monitored Natural Attenuation (MNA) as a remed...
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XENOBIOTIC METABOLISM RESEARCH AND ITS APPLICATION TO HUMAN AND ECOLOGICAL EXPOSURE AND RISK ASSESSMENT |
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A major uncertainty in risk assessment is determining the exposure of a target organism to a chemical stressor, and a confounding factor is the transformation of the chemical to a ...
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e-Estuary: Developing a Decision-support System for Coastal Management |
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platform presentation at a scientific conference...
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v-Tissue 2009: The EU-US Workshop on Virtual Tissues |
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The liver plays a key role in removing chemicals from the body and frequently shows the earliest signs of their harmful effects. Animal testing gives useful information about the e...
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