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| Nazli B. McDonnell, M.D., Ph.D., Staff Clinician Molecular and Clinical Pharmacology Section |
 Dr. Nazli McDonnell graduated from University College Cork and Towson University with a B.A. degree in philosophy and a B.S. degree in chemistry and biology. She subsequently worked as a research assistant in Dr. Jeff Corden's laboratory at Johns Hopkins Medical School, Department of Molecular Biology and Genetics. She completed the M.D./Ph.D. program in University of Maryland Medical School in 1998. Her Ph.D. supervisor was Dr. Michael Summers in the Department of Biochemistry and Molecular Biology at the University of Maryland, Baltimore County. The focus of Dr. McDonnell's Ph.D. research was the study of protein-drug interactions by Nuclear Magnetic Resonance Spectroscopy. Dr. McDonnell's clinical training consisted of a residency in Internal Medicine at York Hospital, Pennsylvania, and a Medical Genetics Fellowship at the Metropolitan Washington D.C. Genetics Fellowship Training Program at National Human Genome Research Institute at the National Institutes of Health. In 2003, Dr. McDonnell joined Dr. Clair Francomano's laboratory at the National Institute on Aging, Laboratory of Genetics to study hereditary disorders of connective tissue. Upon Dr. Francomano's departure, she moved to the Laboratory of Clinical Investigation. Her professional memberships include Sigma Xi, American Medical Association, American Women's Medical Association, American Association for the Advancement of Science, American Society of Human Genetics, and Phi Kappa Phi. |
| Research Interests: Dr. McDonnell's research is focused on clinical and molecular investigations of hereditary disorders of connective tissue (HDCT). The disorders of interest are Ehlers-Danlos syndrome (EDS), Marfan syndrome, Stickler syndrome, hereditary aneurysm syndromes and fibromuscular dysplasia (FMD). Dr. McDonnell is investigating the natural history of these disorders at the NIA-ASTRA Unit, as well as studying genotype/phenotype correlations, molecular and cellular mechanisms and exploring treatment strategies in the laboratory. |
| Contact Information: Laboratory of Clinical Investigation Gerontology Research Center 5600 Nathan Shock Drive Baltimore, MD 21224-6825 Fax 410-558-8538 E mail mcdonnellna@grc.nia.nih.gov For more information about the Laboratory: http://www.grc.nia.nih.gov/branches/lci/mps.htm |
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