Cayman Chemical

Featured Items

SQUISH FISH ARE BACK!

Chemical Structure Database

FABP4 Protein and Assays

4E-BP1 EIA Kits

His-Express Detection EIA Kit

SIRT Recombinant Proteins

8-hydroxy-2-deoxy Guanosine EIA Kit

Apoptotic Blebs Assay Kit

LSD1 Inhibitor Screening Assay Kit

p53 Transcription Factor Assay Kit

KRP 203

New Products

15-deoxy-Δ12,14-Prostaglandin J2 Lipid Maps MS Standard

Prostaglandin K2 Lipid Maps MS Standard

2-methylbenzamide Oxime

Docosahexaenoic Acid ethyl ester

KT 5823

Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.

FABP4 Protein and Assays

FABP4—a new therapeutic target for obesity and diabetes

Cayman Chemical is a leading provider of high-purity, active Fatty Acid Binding Proteins. Contact our sales staff for quotations on bulk preparations of FABP4 and FABP4 assay kits for your drug discovery efforts.

All FABP4 products from Cayman Chemical…

4E-BP1 EIA Kits

4E-BP1—a key regulator of protein translation

Cayman's two new immunometric (i.e., sandwich) assays are designed to accurately detect human Phospho-Thr³⁷/Thr⁴⁶ 4E-BP1 and total 4E-BP1 in cell culture lysates.

Full information for 4E-BP1 EIA Kits...

His-Express Detection EIA Kit

• For the rapid screening of His-tagged recombinant proteins in cell lysates and affinity column fractions

• Use in place of SDS-PAGE for semi-quantitative results in just a few hours

Full information for His-Express Detection Kits...

SIRT Recombinant Proteins

09-24 · SIRT1 (human recombinant) New

Source: recombinant N-terminal GST-tagged SIRT1 amino acids 193-747 purified from E. coli · M_r: 89.2 kDa ·

Details for SIRT1 (human recombinant)...

12-15 · SIRT3 (human recombinant) New

Source: recombinant N-terminal Hexahistidine-tagged SIRT3 amino acids 101-399 purified from E. coli · M_r: 33.5 kDa ·

Details for SIRT3 (human recombinant)...

05-21 · 8-hydroxy-2-deoxy Guanosine EIA Kit

A competitive EIA for quantification of 8-OH-2dG

Cayman’s 8-OH-dG EIA is a competitive assay that can be used for the quantification of 8-OH-dG in urine, cell culture, plasma, and other sample matrices. The EIA utilizes an anti-mouse IgG-coated plate and a tracer consisting of an 8-OH-dG-enzyme conjugate. This …

Details for 8-hydroxy-2-deoxy Guanosine EIA Kit...

02-29 · Apoptotic Blebs Assay Kit

Cayman’s Apoptotic Blebs Assay Kit employs a recombinant protein containing single-chain variable fragments (scFv) of D56R fused to the protein A domain B fraction as an antibody for apoptotic blebs. The protein A portion of this fusion protein is recognized and visualized by fluorescein-conjugated …

Details for Apoptotic Blebs Assay Kit...

10-16 · LSD1 Inhibitor Screening Assay Kit New

A convenient fluorescence-based method for screening LSD1-specific inhibitors

Cayman’s LSD1 Inhibitor Screening Assay Kit provides a convenient fluorescence-based method for screening LSD1-specific inhibitors. The assay is based on the multistep enzymatic reaction in which LSD1 first produces H₂O₂ during the demethylation of lysine 4 on a peptide …

Details for LSD1 Inhibitor Screening Assay Kit...

10-27 · p53 Transcription Factor Assay Kit New

96-Well assay for measurement of p53

Cayman’s p53 Transcription Factor Assay is a non-radioactive, sensitive method for detecting specific transcription factor DNA binding activity in nuclear extracts. A specific-double stranded DNA (dsDNA) sequence containing the p53 response element is immobilized onto the wells of a 96-well plate. …

Details for p53 Transcription Factor Assay Kit...

10-29 · KRP 203 New Excl.

An immune modulator that is a selective S1P₁ receptor agonist

KRP 203 is a selective S1P₁ receptor agonist that has been shown to reduce peripheral lymphocyte infiltration and to prolong survival in rat transplant models. The phosphorylated form of KRP 203 demonstrates a high affinity for the S1P₁ receptor with an ED₅₀ value in the nM range and …

Details for KRP 203...

01-16 · 15-deoxy-Δ^12,14-Prostaglandin J₂ Lipid Maps MS Standard New

Designed for the convenient, precise quantification of 15-deoxy-Δ^12,14-Prostaglandin J₂

15-deoxy-Δ^12,14-Prostaglandin J₂ (15-deoxy-Δ^12,14-PGJ₂) is formed from PGD₂ by the elimination of two molecules of water. It binds selectively to PPARγ with an EC₅₀ value of 2 µM in a murine chimera system. …

Details for 15-deoxy-Δ^12,14-Prostaglandin J₂ Lipid Maps MS Standard...

01-16 · Prostaglandin K₂ Lipid Maps MS Standard New

Designed for the convenient, precise quantification of Prostaglandin K₂

Prostaglandin K₂ (PGK₂) is the 9,11-diketone formed by the oxidation of PGE₂ or PGD₂. Whether this compound exists biologically is uncertain; it is known to be resistant to metabolism by 15-hydroxy PGDH in vitro.

Details for Prostaglandin K₂ Lipid Maps MS Standard...

01-15 · 2-methylbenzamide Oxime New

A synthetic intermediate useful for pharmaceutical synthesis

2-methylbenzamide Oxime is a synthetic intermediate useful for pharmaceutical synthesis.

Details for 2-methylbenzamide Oxime...

01-15 · Docosahexaenoic Acid ethyl ester New

A ω-3 fatty acid ethyl ester

DHA ethyl ester (DHA-EE) is the stabilized ethyl ester form of the ω-3 22:6 fatty acid. Dietary intake of DHA-EE enhances maze-learning ability in old mice. In rats, dietary DHA-EE increases plasma and erythrocyte membrane DHA levels without altering the content of the ω-6 …

Details for Docosahexaenoic Acid ethyl ester...

01-15 · KT 5823 New

Potent selective inhibitor of cGMP-dependent protein kinase (PKG)

KT 5823 is a potent, selective inhibitor of cGMP-dependent protein kinase (PKG) (in vitro IC₅₀ value = 234 nM). KT 5823 is cell-permeable and is often used in intact cells to assess the role of PKG in signaling, although there are cases where it poorly inhibits PKG …

Details for KT 5823...

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