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2000 Publications

  1. Abernethy DR: Aging: Its influence on drug disposition and effect. In Nephrology and Geriatrics Integrated, DG Oreopoulos, WR Hazzard, and R Luke, Eds. Kluwer Academic Publishers, Boston, 2000; pp. 37-45.

  2. Abernethy DR, Flockhart DA. Molecular basis of cardiovascular drug metabolism: implications for predicting clinically important drug interactions. Circ 2000;101:1749-1753.

  3. Abernethy DR, Wainer IW, Anacleto AS. Verapamil metabolite exposure in older and younger men during steady-state oral vapermil administration. Drug Metab Disp 2000;28:760-765.

  4. Ajmani RS, Metter EJ, Jaykumar R, Ingram DK, Spangler EL, Abudo OO, Rifkind JM. Hemodynamic changes during aging associated with cerebral blood flow and impaired cognitive function. Neurobiol of Aging 2000;21:357-269.

  5. Alexandroff AB, Jackson AM, Paterson T, Haley JL, Ross JA, Longo DL, Murphy WJ, James K, Taub DD. Role for CD40-CD40 ligand interactions in the immune response to solid tumors. Mol Immunol 2000;515-526.

  6. Al-Jafari AA, Kamal MA, Alhomida AS, Greig NH. Brain acetylcholinesterase inhibition kinetics of two experimental Alzheimer's disease drugs, phenserine and tolserine, in the rat. J Biochem Mol Biol and Biophys 2000;4:323-335.

  7. An DS, Wersto RP, Agricola BA, Metzger ME, Lu S, Amado RG, Chen ISY, Donahue RE. Marking and gene expression by a lentivirus vector in transplanted human and non-human primate CD34+ cells. J Virol 2000;74:1286-1295.

  8. Andrawis NS, Battle MM, Klamerus KJ, Burghart PH, Neefe L, Weinryb I, Mayer P, Abernethy DR. A pharmacokinetic and pharmacodynamic study of the potential drug interaction between tasosartan and atenolol in patients with stage 1 and 2 essential hypertension. J Clin Pharmacol 2000;40:231-241.

  9. Andrawis N, Jones DS, Abernethy DR. Aging is associated with endothelial dysfunction in the human forearm vasculature. J Am Geriatr Soc 2000;48:193-198.

  10. Andrews J, Bouffard GG, Cheadle C, Lu J, Becker KG, Oliver B. Gene discovery using computational and microarray analysis of transcription in the drosophila melanogaster testis. Genome Res 2000;10(12):2030-43.

  11. Andrisano V, Bertucci C, Cavrini V, Varoli L, Felix G, Wainer IW. Stereoselective binding of 2,3-substituted-3-hydroxy-propionic acids on an immobilized human serum albumin chiral stationary phase: Stereochemical characterization and QSSR study. J Chromatogr A 2000;876:75-86.

  12. Anson RM,Bohr VA. Mitochondria, oxidative damage, and aging. AGE 2000;199-218.

  13. Anson RM, Hudson E, Bohr VA. Mitochondrial endogenous oxidative damage has been overestimated. FASEB 2000;14:355-360.

  14. Arrington ED, Caldwell MC, Kumaravel TS, Lohani A, Joshi A, Evans MK, Chen H, Nussenzweig A, Holbrook NJ, Gorospe M. Enhanced sensitivity and long-term G2 arrest in hydrogen peroxide-treated Ku80-null cells are unrelated to DNA repair defects. Free Rad Biol Med 2000;29:1166-1176.

  15. Arun B, Curti BD, Longo DL, Stevens D, Alvord WG, Gause BL, Watson T, Kopp WC, Janik JE. Elevations in serum soluble interleukin-2 receptor levels predict relapse in patients with hairy cell leukemia. Cancer J Sci Am 2000;6:21-24.

  16. Aspelund G, Egan JM, Slezak LA, Sritharan KC, Elahi DE, Andersen DK. Glucagon like peptide-1 and exendin-4 improve glucose tolerance and induce islet cell growth during chronic pancreatitis in rats. Surgical Forums 2000;L1:40-42.

  17. Auclair B, Wainer IW, Fried K, Koch P, Jerussi TP, Ducharme MP. A population analysis of nebulized (R)-albuterol in dogs using a novel mixed gut-lung absorption PK-PD model. Pharm Res 2000;17:1228-1235.

  18. Babar SI, Enright PL, Boyle P, Foley D, Sharp DS, Petrovitch H, Quan SF. Sleep disturbances and their correlates in elderly Japanese-American men residing in Hawaii. J Gerontol A Biol Sci Med Sci 2000;55:M406-M411.

  19. Baek JY, Jun DY, Taub D, Kim YH. Protein, Nucleotide assignment of human 3-phosphoglycerate dehydrogenase (PHGDH) to human chromosome band 1p12 by fluorescence in situ hybridization. Cytogenet Cell Genet 2000;89:6-7.

  20. Bagrov AY, Dmitrieva RI, Dorofeeva NA, Fedorova OV, Lopatin DA, Lakatta EG, Droy-Lefaix MT. Cicletanine reverses vasoconstriction induced by the endogenous sodium pump ligand, marinobufagenin, via a protein kinase C dependent mechanism. J Hypertension 2000;18:209-15.

  21. Bagrov AY, Lakatta EG, Fedorova OV. Marinobufagenin, an endogenous bufodienolide sodium pump inhibitor. In: Na/K-ATPase and Related ATPases. K. Tangiguchi and S. Kaya (Eds), Elsevier Science BV, Amsterdam 2000; pp. 647-654.

  22. Balajee AS, Bohr VA. Genomic heterogeneity of nucleotide excision repair. Gene 2000;250:15-30.

  23. Balajee AS, DeSantis LP, Brosh RM Jr, Selzer R, Bohr VA. Role of the ATPase domain of the Cockayne syndrome group B protein in UV induced apoptosis. Oncogene 2000;19:477-489.

  24. Barker N, Morin PJ, Clevers H. The Yin-Yang of TCF/b-catenin signaling. In: Advances in Cancer Research.Vande Woude GF, Klein G. (Eds.): San Diego, Academic Press, 2000, pp. 1-24.

  25. Becker KG, White SL, Muller J, Engel J. BBID: the biological biochemical image database. Bioinformatics 2000;16:745-747.

  26. Bendriss E-K, Markoglou N, Wainer IW. A liquid chromatographic method for the simultaneous determination of caffeine and fourteen caffeine metabolites in urine. J Chromatogr B 2000;746:331-338.

  27. Berger K, Breteler MMB, Helmer C, Inzitari D, Fratiglioni L, Trenkwalder C, Hofman A, Launer LJ. Prognosis with Parkinson�s disease in Europe: A collaborative study of population based cohorts. Neurologic Diseases in the Elderly Research Group. Neurology 2000;54(11 Suppl 5):24-27.

  28. Bernier M, Kole HK, Montrose-Rafizadeh C, Kole S. Discrete region of the insulin receptor carboxyl terminus plays key role in insulin action. J Cell Biochem. 2000;78:160-169.

  29. Black SE, Moffat SD, Yu DC, Parker J, Stanchev P, Bronskill M. Callosal atrophy correlates with temporal lobe volume and mental status in Alzheimer's disease. Canadian J Neurol Sci 2000;27(3):204-209.

  30. Blazer DG, Hybels CF, Simonsick EM, Hanlon JT. Marked differences in antidepressant use by race in an elderly community sample. Am J Psychiatry 2000;157:1089-1094.

  31. Bochar DA, Savard J, Wang W, Lafleur DW, Moore P, Cote J, Shiekhattar R. A family of chromatin remodeling factors related to Williams syndrome transcription factor. Proc Natl Acad Sci USA 2000;97:1038-1043.

  32. Bochar DA, Wang L, Beniya H, Kinev A, Xue Y, Lane WS, Wang W, Kashanchi F, Shiekhattar R. BRCA1 is associated with a human SWI/SNF-related complex: Linking chromatin remodeling to breast cancer. Cell 2000;102:257-265.

  33. Bohr VA. DNA damage. Encyclopedia of Molecular Medicine 2000;5:1067-1070.

  34. Bohr VA. DNA damage and repair. Article RLS 153. The MacMillan Encyclopedia of Aging. 2000.

  35. Bohr VA. DNA repair pathways and changes in Cancer. DNA Alterations in Cancer: Genetic and Epigenetic Changes, 2000;167-176.

  36. Bohr VA, Cooper MP, Orren DK, Machwe A, Piotrowski J, Sommers J, Karmakar P, Brosh RM Jr. Werner syndrome protein: biochemical properties and functional interactions. Exp Gerontol 2000;695-702.

  37. Bohr VA, Dianov GL, Balajee AS, Nehlin JO, Machwe A, Gray MD, Brosh RM Jr, Dianova I, Orren DK. DNA repair and transciption in human premature aging syndromes. Molecular Biology of Aging 2000;262-272.

  38. Bohr VA, Gilchrest BA. In The role of DNA damage and repair in Cell Aging. Cell Aging and Gerontology 2000.

  39. Brock DB, Beckett LA, Bienias JL. Sample surveys (an update). In: Gail MH, Benichou J eds. Encyclopedia of Epidemiologic Methods. Chichester, UK: John Wiley and Sons, Ltd. 2000.

  40. Brosh RM Jr, Karow JK, White EJ, Shaw ND, Hickson ID, Bohr VA. Potent inhibition of Werner and Bloom helicases by DNA minor groove binding drugs. Nucleic Acids Res 2000;28: 2420-2430.

  41. Brosh Jr. RM, Li J-L, Kenny MK, Karow JK, Cooper MP, Kureekattil RP, Hickson ID, Bohr VA. Replication protein A physically interacts with the Bloom�s Syndrome Protein and stimulates its helicase activity. J Biol Chem 2000;275:23500-23508.

  42. Brosh RM Jr, Majumdar A, Desai S, Hickson ID, Bohr VA, Seidman MM. Unwinding of a DNA triple helix by the werner and bloom syndrome helicase. J Biol Chem 2000;3024-3030.

  43. Bruce-Keller AJ, Keeling JL, Keller JN, Huang FF, Camandola S, Mattson MP. Antiinflammatory effects of estrogen on microglial activation. Endocrinol 2000;141: 3646-3656.

  44. Camandola S, Mattson MP. The lipid peroxidation product 4-hydroxy-2,3-nonenal inhibits constitutive and inducible activity of NF-kB in neurons. Mol Brain Res 2000;85:53-60.

  45. Camandola S, Mattson MP. The pro-apoptotic action of Par-4 involves inhibition of NF-kB activity and suppression of Bcl-2 expression. J Neurosci Res 2000;61:134-139.

  46. Canella KA, Seidman MM. Mutation spectra in supF: approaches to elucidating sequence context effects. Mutat Res 2000;450:61-73.

  47. Carmelli D, DeCarli C, Swan GE, Kelly-Hayes M, Wolf PA, Reed T, Guralnik JM. The joint effect of apolipoprotein E epsilon4 and MRI findings on lower-extremity function and decline in cognitive function. J Gerontol A Biol Sci Med Sci 2000;55:M103-M109.

  48. Carmelli D, Kelly-Hayes M, Wolf PA, Swan GE, Jack LM, Reed T, Guralnik JM. The contribution of genetic influences to measures of lower-extremity function in older male twins. J Gerontol Biol Sci Med Sci 2000;55:B49-B53.

  49. Carmona GN, Jufer R, Cone EJ, Greig N, Yu QS, Goldberg SR, Schindler CW. Butyrylcholinesterase accelerates Coacaine metabolism: in vitro and in vivo effects in non-human primates and humans. Drug Metabol Dis 2000;28:267-371.

  50. Carter MG, Johns MA, Zeng X, Zhou L, Zink MC, Mankowski JL, Donovan DM, Baylin SB. Mice deficient in the candidate tumor suppressor gene Hic1 exhibit developmental defects of structures affected in the Miller-Dieker syndrome. Human Mol Gen 2000;9:413-419.

  51. Chase D, Serafinas C, Ashcroft N, Kosinski M, Longo D, Ferris DK, Golden A. The polo-like kinase PLK-1 is required for nuclear envelope breakdown and the completion of meiosis in Caenorhabditis elegans. Genesis 2000;26:26-41.

  52. Chen-Izu Y, Xiao R-P, Izu LT, Cheng H, Kuschel M, Spurgeon H, Lakatta EG. Gi- dependent localization of b-adrenergic receptor signaling to L-type Ca2+ channels. Biophys J 2000;79:2547-2556.

  53. Chesley A, Lundberg M, Asai T, Xiao R-P, Ohtani S, Lakatta E, Crow M. The b-adrenergic receptor delivers an anti-apoptotic signal to cardiac myocytes through G1-dependent coupling to phosphatidylinositol 3-kinase. Circ Res 2000;87:1172-1179.

  54. Chou SR, Brownell A, Ko MSH, Kaplan J. Interferon gamma receptor gene: key role in determining accessibility of NK-triggeringantigens to recognition by self-reactive NK cells. Cell Immunol 2000;15;200:88-97.

  55. Christiansen M, Stevnsner T, Bohr VA, Clark BF, Rattan SI. Gene-specific DNA repair of pyrimidine dimers does not decline during cellular aging in vitro. Exp Cell Res 2000;256:308-314.

  56. Ciccodicola A, D�Esposito M, Esposito T, Gianfrancesco F, Migliaccio C, Miano MG, Matarazzo MR, Vacca M, Franz� A, Cuccurese M, Cocchia M, Curci A, Terrancciano A, Torino A, Cocchia S, Mercadante G, Pannone E, Archidiacono N, Rocchi M, Schlessinger D, D�Urso M. Differentially regulated and evolved genes in the fully sequenced Xq pseudoautosomal region. Human Molecular Genetics 2000;12:395-401.

  57. Clocquet AR, Egan JM, Stoffers DA, Muller DC, Wideman L, Chin GA, Clark WL, Hanks JB, Habener JF, Elahi D. Impaired insulin secretion and increased insulin sensibility in familial maturity-onset diabetes of the young 4 (insulin promoter factor 1 gene). Diabetes 2000;49:1856-1864.

  58. Cocchia M, Huber R, Pantano S, Chen EY, Ma P, Forabosco A, Ko MSH, Schlessinger D. PLAC1, an Xq26 gene with placenta specific expression. Genomics 2000;68:305-312.

  59. Cocchia M,Kouprina N, Kim S-J, Larionov V, Schlessinger D, Nagaraja R. Recovery and potential utility of YACs as circular YACs/BACs. Nucleic Acids Res 2000;28:1-8.

  60. Cohen HJ, Pieper CF, Hanlon JT, Wall WE, Burchett BM, Havlik RJ. Calcium channel blockers and cancer. Am J Med 2000;108:210-215.

  61. Constantinou A, Tarsounas M, Karow JK, Brosh Jr RM, Bohr VA, Hickson ID, West SC. The Werner's syndrome Protein (WRN) translocates Holliday Junctions in vitro and colocalises with RPA upon replicatin arrest. EMBO Reports 2000;80-84.

  62. Cooper MP, Machwe A, Orren DK, Brosh RM, Ramsden D, Bohr VA. Ku complex interacts with and stimulates the Werner protein. Res Comm 2000;14:907-912.

  63. Costa PT Jr, Herbst JH, McCrae RR, Siegler IC. Personality at midlife: Stability, intrinsic maturation, and response to life events. Assessment 2000;7:367-380.

  64. Costa PT Jr, McCrae RR. A theoretical context for adult temperament. In TD Wachs, GA Kohnstamm (Eds.): Temperament in context. Hillsdale, NJ: Lawrence Erlbaum Associates, 2000, 1-21.

  65. Costa PT Jr, McCrae RR. Innovations in assessment using the revised NEO personality inventory: introduction to the special issue. Assessment 2000;7:323-325.

  66. Costa PT Jr, McCrae RR. NEO Personality Inventory. In: A.E. Kazdin (Ed.): Encyclopedia of Psychology, Washington, DC: American Psychological Association, 2000,(Vol. 5), pp. 407-409.

  67. Costa PT Jr, McCrae RR. Theories of personality and psychopathology: Approaches derived from philosophy and psychology. In: H.I. Kaplan, and B.J. Sadock (Eds.): Comprehensive textbook of psychiatry. (7th ed), Baltimore: Williams and Wilkins 2000, pp 638-651.

  68. Costa PT Jr, McCrae RR, Martin TA, Oryol VE, Senin IG, Rukavishnikov AA, Shimonaka Y, Nakazato K, Gondo Y, Takayama M, Allik J, Kallasmaa T, Realo A. Personality development from adolescence through adulthood: Further cross-cultural comparisons of age differences. In: Molfese VJ, Molfese D (eds.), Temperament and Personality Development Across the Life Span. Hillsdale, NJ: Lawrence Erlbaum Associates, 2000, pp. 235-252.

  69. Davydova NN, Yasuda SU, Woosley RL, Wainer IW. Determination of clemastine in human plasma by gas chromatography with nitrogen-phosphorous detection. J Chromatogr B 2000;744:177-182.

  70. de Rijk MC, Launer LJ, Berger K, Breteler MMB, Dartigues J-F, Baldereschi M, Fratiglioni L, Lobo A, Martinez-Lage J, Trenkwalder C, Hofman A. Prevalence of Parkinson�s disease in Europe: A collaborative study of population-based cohorts. Neurol 2000;54(11 Suppl 5):21-23.

  71. Deutsch J, Kalderon B, Purdon AD, Rapoport SI. Evaluation of brain long-chain acylcarnitines during cerebral ischemia. Lipids 2000;6:693-696.

  72. Dianov GL, Thybo T, Dianova IL, Lipinski LJ, Bohr VA. Single nucleotide patch base excision repair is the major pathway for removal of thymine glycol from DNA in human cell extracts. J Biol Chem 2000;275:11809-11813.

  73. Dibrov P, Murtazine R, Kinsella J, Fliegel L. Characterization of a histidine rich cluster of amino acids in the cytoplasmic domain of the Na+/H+ exchanger. In: Bioscience Rep. Vol. 20(3). Plenum Publishing Corporation 2000, pp 185-197.

  74. Di Carlo A, Launer LJ, Breteler MMB, Fratiglioni L, Lobo A, Martinez-Lage J, Schmidt R, Hofman A. Frequency of stroke in Europe: A collaborative study of population-based cohorts. ILSA Working Group and the Neurologic Diseases in the Elderly Research Group. Italian Longitudinal Study on Aging. Neurology 2000;54(11 Suppl 5):28-33.

  75. Di Marco, MP, Wainer, IW, Granvil CL, Batist G, Ducharme, MP. New insights into the pharmacokinetics and metabolism of (R,S)-ifosfamide in cancer patients using a population pharmacokinetics model. Pharm Res 2000;17:645-652.

  76. Dmitrieva RI, Bagrov AY, Lalli E, Sassone-Corsi P, Stocco DM, Doris PA. Mammalian bufodienolide is synthesized from cholesterol in the adrenal cortex by a pathway which is independent of cholesterol side-chain cleavage. Hypertension 2000;36:442-448.

  77. Donahue RE, Wersto RP, Allay JS, Agricola BA, Metzger ME, Nienhuis AW, Persons DA, Sorrentino BP. High levels of lymphoid tranduction of enhanced green fluorescent protein in non-human primates transplanted with cytokine-mobilized peripheral blood CD34+ cells. Blood 2000;95:445-452.

  78. Duan W, Guo Z, Mattson MP. Brain-derived neurotrophic factor mediates an excitoprotective effect of dietary restriction in mice. J Neurochem 2000;76:619-626.

  79. Duan W, Guo Z, Mattson MP. Participation of Par-4 in the degeneration of striatal neurons induced by metabolic compromise with 3-nitropropionic acid. Exp Neurol 2000;165:1-11.

  80. Duncan MD, Tihan T, Donovan DM, Phung QH, Rowley DL, Harmon JW, Gearhart PJ, Duncan KL. Esophagogastric adenocarcinoma in an E1A/E1B transgenic model involves p53 disruption. J Gastrointest Surg 2000;4:290-297.

  81. Dunn BK, Longo DL. Molecular biology and biological markers. In: Hunter CP, Johnson KA, Muss HB (Eds.): Cancer in the Elderly, New York, Marcel Dekker 2000, pp. 69-121.

  82. Eisenrauch A, Blaustein MP, Juhaszova, M. Regulatory processes on the cytoplasmic surface of the Na+/Ca2+ exchanger from lobster exoskeletal muscle. J Membrane Biol 2000;174:225-235.

  83. Elahi D, Muller DC. Carbohydrate metabolism in the elderly. Eur J Clin Nutr 2000;54 Suppl 3:S112-S120.

  84. Fauerbach JA, Lawrence JW, Schmidt CW Jr, Munster AM, Costa PT Jr. Personality predictors of injury-related posttraumatic stress disorder. Journal of Nervous and Mental Disease 2000;188:510-517.

  85. Faruqi AF, Datta HJ, Carroll D, Seidman MM, Glazer PM. Triple-helix formation induces recombination in mammalian cells via a nucleotide excision repair-dependent pathway. Mol Cell Biol 2000;20:990-1000.

  86. Fedorova OV, Lakatta EG, Bagrov AY. Endogenous Na, K pump ligands are differentially regulated during acute NaCl loading of Dahl rats. Circ 2000;102:3009-3014.

  87. Fedorova OV, Lakatta EG, Bagrov AY. Marinobufagenin and cardiovascular remodeling in Dahl rats on a high NaCl diet. In: Na/K-ATPase and Related ATPases. K. Tangiguchi and S. Kaya (Eds), Elsevier Science BV, Amsterdam 2000, pp. 685-688.

  88. Ferrucci L, Bandinelli S, Benvenuti E, Di Iorio A, Macchi C, Harris TB, Guralnik JM. Subsystems contributing to the decline in ability to walk: Bridging the gap between epidemiology and geriatric practice in the In CHIANTI Study. J Am Geriatr Soc 2000;48:1618-25.

  89. Ferrucci L, Penninx BW, Leveille SG, Corti MC, Pahor M, Wallace R, Harris TB, Havlik RJ, Guralnik JM. Characteristics of nondisabled older persons who perform poorly in objective tests of lower extremity function. J Am Geriatr Soc 2000;48:1102-1110.

  90. Fillenbaum GG, Pieper CF, Cohen HJ, Cornoni-Huntley JC, Guralnik JM. Comorbidity of five chronic health conditions in elderly community residents: determinants and impact on mortality. J Gerontol A Biol Sci Med Sci 2000;55:M84-M89.

  91. Finkel T, Holbrook NJ. Oxidants, oxidative stress and the biology of aging (Insight Review). Nature 2000;408:239-247.

  92. Fleg JL. Arrhythmias and conduction disturbances. In: Beers M, Berkow R, eds. The Merck Manual of Geriatrics. 3rd Edition. Whitehouse Station, NJ; 2000, pp. 885-900.

  93. Fleg JL. Cardiovascular benefits of aerobic exercise in older adults. In: S. Harris, ed. Prevention and Aging 2000, pp. 7-21.

  94. Fleg JL. Diagnostic Evaluation. In: Beers M, Berkow R, eds. The Merck Manual of Geriatrics. 3rd Edition. Whitehouse Station, NJ 2000, pp. 822-832.

  95. Fleg JL, Pina IL, Balady GJ, Chaitman BL, Fletcher B, Lavie C, Limacher M, Stein R, Williams M, Bazzarre T. Assessment of functional capacity in clinical and research applications. Circ 2000;102(13):1591-1597.

  96. Foley DJ, Masaki KH, Ross GW, White LR. Driving cessation in older men with incident dementia. J Am Geriatr Soc 2000;48:928-930.

  97. Fratiglioni L, Launer LJ, Andersen K, Breteler MMB, Copeland RJM, Dartigues J-F, Lobo A, Martinez-Lage J, Soininen H, Hofman A. Incidence of dementia and major subtypes in Europe: A collaborative study of population-based cohorts. Neurologic Diseases in the Elderly Research Group. Neurol 2000;54(11 Suppl 5):S10-S15.

  98. Freeman RQ, Giovannetti T, Lamar M, et al. Visuoconstructional problems in dementia: contribution of executive systems functions. Neuropsychology 2000;14(3):415-426.

  99. Fried LP, Guralnik JM, Baggio G. Forward to Special Issue on Women and Aging. Aging Clin Exp Res 2000;12:63-64.

  100. Friedman BH, Thayer JF, Borkovec TD. Explicit memory bias for threat words in generalized anxiety disorder. Behavior Therapy 2000;31:745-756.

  101. Furlong MT, Morin PJ. Rare activation of the TCF/b-catenin pathway in ovarian cancer. Gyn Onc 2000;77:97-104.

  102. Furey ML, Pietrini P, Alexander GE, Mentis MJ, Szczepanik J, Shetty U, Greig NH, Holloway HW, Schapiro MB, Freo U. Time course of pharmacodynamic and pharmacokinetic effects of physostigmine assessed by functional brain imaging in humans. Pharmacol Biochem Behav 2000;66:475-481.

  103. Garant MJ, Maksimova E, Montrose-Rafizadeh C, Lee-Kwon W, Kole S, Bernier M. Cysteine 981of the human insulin receptor is required for covalent cross-linking between beta-subunit and a thiol-reactive membrane-associated protein. Biochemistry 2000;39:7178-7187.

  104. Garrido R, Mattson MP, Hennig B, Toborek B. Nicotine protects against arachidonic acid-induced caspase activation, cytochrome c release, and apoptosis of cultured spinal cord neurons. J Neurochem 2000;76:1395-1403.

  105. Gasper PW. The Hemopoietic Microenvironment: The Fifth Edition of Schalm�s Veterinary Hematology, Lippincott Williams and Wilkins, Philadelphia, 2000.

  106. Gasper PW. Hemopoietic Stem Cell Biology: The Fifth Edition of Schalm�s Veterinary Hematology, Lippincott Williams and Wilkins, Philadelphia, 2000.

  107. Gasper PW. The Hemopoietic System: The Fifth Edition of Schalm�s Veterinary Hematology, Lippincott Williams and Wilkins, Philadelphia, 2000.

  108. Gasper PW, Thrall, MA: Hemopoietic Stem Cell Transplantation. The Fifth Edition of Schalm�s Veterinary Hematology, Lippincott Williams and Wilkins, Philadelphia, 2000.

  109. Geleijnse JM, Witteman JC, Launer LJ, Lamberst SW, Pols HA. Tea and coronary heart disease: Protection through estrogenlike activity? Arch Intern Med 2000;160:3328-3329.

  110. Germanier M, Defais M, Bohr VA, Larminat F. Transcription-coupled repair is inducible in hamster cells. Nucleic Acids Res 2000;28:4674-4678.

  111. Glazner GW, Camandola S, Mattson MP. Nuclear factor-kB mediates the cell survival-promoting action of an activity-dependent neurotrophic factor peptide-9. J Neurochem 2000;75:101-108.

  112. Glynn RJ, Chae CU, Guralnik JM, Taylor JO, Hennekens CH. Pulse pressure and mortality in older people. Arch Intern Med 2000;160:2765-72.

  113. Gowdak LHW, Poliakova L, Li Z, Grove R, Lakatta EG, Talan M: Induction of angiogenesis by cationic lipid-mediated VEGF165 gene transfer in the rabbit ischemic hindlimb model. J Vasc Surg 2000;32:343-52.

  114. Gowdak LH, Poliakova L, Wang X, Kovesdi I, Fishbein KW, Zacheo A, Palumbo R, Straino S, Emanueli C, Marrocco-Trischitta M, Lakatta EG, Anversa P, Spencer RG, Talan M, Capogrossi MC. Adenovirus-Mediated VEGF(121) Gene transfer stimulates angiogenesis in normoperfused skeletal muscle and preserves tissue perfusion after induction of ischemia. Circ 2000;102(5):565-571.

  115. Granger CB, Keavney B, Francomano C, Olsson G, Yusuf S. Recommendations for national and local regulatory authorities concerning research in genetic markers of disease. Am Heart J 2000;140:53-55.

  116. Greig N, Brossi, A, DeMicheli, E, Holloway HW, Yu QS, Deutsch, J, Ingram D, Soncrant, T. The experimental Alzheimer drug phenserine: Preclinical pharmacokinetics and pharmacodynamics. Acta Neurologica Scandinavica 2000; 176:74-84.

  117. Greig N, DeMicheli E, Utsuki T, Holloway HW, Yu QS, Perry TA, Brossi A, Deutsch J, Ingram D, Lahiri DK, Soncrant T. The experimental Alzheimer drug phenserine: pharmacodynamics and kinetics in the rat. Acta Neurol Scand 2000;102:74-84.

  118. Guo Z, Ersoz A, Butterfield DA, Mattson MP. Beneficial effects of dietary restriction on cerebral cortical synaptic terminals: preservation of glucose transport and mitochondrial function after exposure to amyloideta-peptide and oxidative and metabolic insults. J Neurochem 2000;75:314-320.

  119. Guralnik JM, Balfour JL, Volpato S. The ratio of older women to men: Historical perspective and cross-national comparisons. Aging Clin Exp Res 2000;12:65-76.

  120. Guralnik JM, Ferrucci L, Pieper CF, Leveille SG, Markides KS, Ostir GV, Studenski S, Berkman LF, Wallace RB. Lower extremity function and subsequent disability: Consistency across studies, predictive models, and value of gait speed alone compared to the Short Physical Performance Battery. J Gerontol A Bio Sci Med Sci 2000;55:M221-M231.

  121. Guralnik JM, Havlik RJ. Demographics. In: Beers, MH, Berkow R. eds. Merck Manual of Geriatrics, Third edition. Whitehouse Station, NJ: Merck and Co. 2000;9-23.

  122. Hagemann D, Kuschel M, Kuramochi R, Zhu W, Cheng H, Xiao R-P. Frequency-encoding Thr17 phospholamban phosphorylation is independent of Ser16 phosphorylation in cardiac myocytes. J Biol Chem 2000;275:22532-22536.

  123. Haltiwanger BM, Matsumoto Y, Nicolas E, Dianov GL, Bohr VA, Taraschi TF. DNA base excision repair in human malaria parasites is predominantly by a long-patch pathway. Biochemistry 2000;39:763-772.

  124. Harris TB, Visser M, Everhart J, Cauley JA, Tylavsky F, Fuerst T, Zamboni M, Taaffe D, Resnick H, Scherzinger A, Nevitt M. Waist circumference and sagittal diameter reflect total fat better than visceral fat in older men and women: The Health, Aging and Body Composition Study. Ann NY Acad Sci 2000;904:462-473.

  125. Havlik RJ, Guralnik J, Sayer B, Pahor M, Cohen H. Antihypertensive drugs and gastrointestinal hemorrhage: causation or confounding? [Letter to The Editor] Gastroenterology 2000;119(5):1416-1417.

  126. Havlik RJ, Izmirlian G, Petrovitch H, Ross GW, Masaki K, Curb JD, Saunders AM, Foley DJ, Brock D, Launer LJ, White L. APOE-epsilon4 predicts incident AD in Japanese-American men: The Honolulu-Asia Aging Study. Neurology 2000;54:1526-1529.

  127. Haydar ZR, Blackman MR, Tobin JD, Wright JG, Fleg JL. Relationship between aerobic capacity and circulating IGF-1 levels in healthy men and women. J Am Geriatric Society 2000;48:139-145.

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