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2008-Publications

  1. Abdelmohsen K, Kuwano Y, Kim HH, Gorospe M. Posttranscriptional gene regulation by RNA-binding proteins during oxidative stress: implications for cellular senescence. Biol Chem. 2008;389(3):243-255.

  2. Ahmet I, Krawczyk M, Zhu W, Woo AY, Morrell C, Poosala S, Xiao RP, Lakatta EG, Talan MI. Cardioprotective and survival benefits of long-term combined therapy with {beta}2 AR agonist and {beta}1 AR blocker in dilated cardiomyopathy post-myocardial infarction. J Pharmacol Exp Ther. 2008;325(2):491-499.

  3. Aid S, Langenbach R, Bosetti F. Neuroinflammatory response to lipopolysaccharide is exacerbated in mice genetically deficient in cyclooxygenase-2. J Neuroinflammation. 2008;5(1):17.

  4. Anderson DE, Fedorova OV, Morrell CH, Longo DL, Kashkin VA, Metzler JD, Bagrov AY, Lakatta EG. Endogenous sodium pump inhibitors and age-associated increases in salt sensitivity of blood pressure in normotensives. Am J Physiol Regul Integr Comp Physiol. 2008;294(4):R1248-R1254.

  5. Ankle Brachial Index Collaboration, Fowkes FG, Murray GD, Butcher I, Heald CL, Lee RJ, Chambless LE, Folsom AR, Hirsch AT, Dramaix M, deBacker G, Wautrecht JC, Kornitzer M, Newman AB, Cushman M, Sutton-Tyrrell K, Fowkes FG, Lee AJ, Price JF, d'Agostino RB, Murabito JM, Norman PE, Jamrozik K, Curb JD, Masaki KH, Rodr�guez BL, Dekker JM, Bouter LM, Heine RJ, Nijpels G, Stehouwer CD, Ferrucci L, McDermott MM, Stoffers HE, Hooi JD, Knottnerus JA, Ogren M, Hedblad B, Witteman JC, Breteler MM, Hunink MG, Hofman A, Criqui MH, Langer RD, Fronek A, Hiatt WR, Hamman R, Resnick HE, Guralnik J, McDermott MM. Ankle brachial index combined with Framingham risk score to predict cardiovascular events and mortality: a meta-analysis. JAMA. 2008;300(2):197-208.

  6. Araki Y, Fann M, Wersto R, Weng NP. Histone acetylation facilitates rapid and robust memory CD8 T cell response through differential expression of effector molecules (Eomesodermin and its targets: Perforin and Granzyme B). J Immunol. 2008;180(12):8102-8108.

  7. Arnaud-Lopez L, Usala G, Ceresini G, Mitchell BD, Pilia MG, Piras MG, Sestu N, Maschio A, Busonero F, Albai G, Dei M, Lai S, Mulas A, Crisponi L, Tanaka T, Bandinelli S, Guralnik JM, Loi A, Balaci L, Sole G, Prinzis A, Mariotti S, Shuldiner AR, Cao A, Schlessinger D, Uda M, Abecasis GR, Nagaraja R, Sanna S, Naitza S. Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function. Am J Hum Genet. 2008;82(6):1270-1280.

  8. Arumugam TV, Selvaraj PK, Woodruff TM, Mattson MP. Targeting ischemic brain injury with intravenous immunoglobulin. Expert Opin Ther Targets. 2008;12(1):19-29.

  9. Arumugam TV, Woodruff TM, Lathia JD, Selvaraj PK, Mattson MP, Taylor SM. Neuroprotection in stroke by complement inhibition and immunoglobulin therapy. Neuroscience. 2008 July. [Epub ahead of print].

  10. Bagby RM, Quilty LC, Segal ZV, McBride CC, Kennedy SH, Costa PT. Personality and differential treatment response in major depression: a randomized controlled trial comparing cognitive-behavioural therapy and pharmacotherapy. Can J Psychiatry. 2008;53(6):361-370.

  11. Bandmann O, Singleton AB. Yet another spinocerebellar ataxia: the saga continues. Neurology. 2008 ;71(8):542-543.

  12. Bagrov AY, Shapiro JI. Endogenous digitalis: pathophysiologic roles and therapeutic applications. Nat Clin Pract Nephrol. 2008;4(7):378-392.

  13. Bartali B, Frongillo EA, Guralnik JM, Stipanuk MH, Allore HG, Cherubini A, Bandinelli S, Ferrucci L, Gill TM. Serum micronutrient concentrations and decline in physical function among older persons. JAMA. 2008;299(3):308-315.

  14. Basselin M, Chang L, Chen M, Bell JM, Rapoport SI. Chronic administration of valproic acid reduces brain NMDA signaling via arachidonic acid in unanesthetized rats. Neurochem Res. 2008 May. [Epub ahead of print].

  15. Basselin M, Chang L, Chen M, Bell JM, Rapoport SI. Chronic carbamazepine administration attenuates dopamine D(2)-like receptor-initiated signaling via arachidonic acid in rat brain. Neurochem Res. 2008 Feb.; [Epub ahead of print].

  16. Baum AE, Akula N, Cabanero M, Cardona I, Corona W, Klemens B, Schulze TG, Cichon S, Rietschel M, Nothen MM, Georgi A, Schumacher J, Schwarz M, Abou Jamra R, Hofels S, Propping P, Satagopan J, Detera-Wadleigh SD, Hardy J, McMahon FJ. A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder. Mol Psychiatry. 2008;13(2):197-207.

  17. Beason-Held LL, Kraut MA, Resnick SM. I. Longitudinal changes in aging brain function. Neurobiol Aging. 2008;29(4):483-496.

  18. Beason-Held LL, Kraut MA, Resnick SM. II. Temporal patterns of longitudinal change in aging brain function. Neurobiol Aging. 2008;29(4):497-513.

  19. Beck J, Ferrucci L, Sun K, Fried LP, Varadhan R, Walston J, Guralnik JM, Semba RD. Circulating oxidized low-density lipoproteins are associated with overweight, obesity, and low serum carotenoids in older community-dwelling women. Nutrition. 2008 June. [Epub ahead of print].

  20. Becker RE, Greig NH. Alzheimer�s disease drug development in 2008 and beyond: problems and opportunities. Curr Alzheimer Res. 2008;5(4):346-357.

  21. Berquist BR, McNeill DR, Wilson DM 3rd. Characterization of abasic endonuclease activity of human Ape1 on alternative substrates, as well as effects of ATP and sequence context on AP site incision. J Mol Biol. 2008;379(1):17-27.

  22. Beydoun MA, Beason-Held LL. Does hypertension interact with body weight to impact cognitive function in the elderly?: Emerging evidence. Am J Hypertens. 2008;21(6):603.

  23. Bezprozvanny I, Mattson MP. Neuronal calcium mishandling and the pathogenesis of Alzheimer�s disease. Trends Neurosci. 2008 July. [Epub ahead of print].

  24. Bhatia P, Kolinski M, Moaddel R, Jozwiak K, Wainer IW. Determination and modelling of stereoselective interactions of ligands with drug transporters: A key dimension in the understanding of drug disposition. Xenobiotica. 2008;38(7):656-675.

  25. Bhattacharjee AK, Chang L, Chen M, White L, Bell JM, Bazinet RP, Rapoport SI. Chronic d-amphetamine depresses an imaging marker of arachidonic acid metabolism in rat brain. Int J Neuropsychopharmacol. 2008;23:1-13.

  26. Bhattacharjee AK, Chang L, White L, Bazinet RP, Rapoport SI. Imaging apomorphine stimulation of brain arachidonic acid signaling via D(2)-like receptors in unanesthetized rats. Psychopharmacology (Berl). 2008 Feb.; [Epub ahead of print].

  27. Biragyn A, Coscia M, Nagashima K, Sanford M, Young HA, Olkhanud P. Murine {beta}-defensin 2 promotes TLR-4/MyD88-mediated and NF-{kappa}B-dependent atypical death of APCs via activation of TNFR2. J Leukoc Biol. 2008;83(4):998-1008.

  28. Bjornsson HT, Sigurdsson MI, Fallin MD, Irizarry RA, Aspelund T, Cui H, Yu W, Rongione MA, Ekstr�m TJ, Harris TB, Launer LJ, Eiriksdottir G, Leppert MF, Sapienza C, Gudnason V, Feinberg AP. Intra-individual change over time in DNA methylation with familial clustering. JAMA. 2008;299(24):2877-2883.

  29. Bosetti F, Toscano CD. Is it time to standardize ethics guiding the peer review process? Lipids. 2008;43(2):107-108.

  30. Branch-Mays GL, Dawson DR, Gunsolley JC, Reynolds MA, Ebersole JL, Novak KF, Mattison JA, Ingram DK, Novak MJ. The effects of a calorie-reduced diet on periodontal inflammation and disease in a non-human primate model. J Periodontol. 2008;79(7):1184-1191.

  31. Bras J, Guerreiro R, Ribeiro M, Morgadinho A, Januario C, Dias M, Calado A, Semedo C, Oliveira C, Hardy J, Singleton A. Analysis of Parkinson disease patients from Portugal for mutations in SNCA, PRKN, PINK1 and LRRK2. BMC Neurol. 2008 Jan.;8(1):1 [Epub ahead of print].

  32. Brosh RM Jr. DNA repair as a target for anti-cancer therapy. Anticancer Agents Med Chem. 2008;8(4):350.

  33. Brummett BH, Siegler IC, Day RS, Costa PT. Personality as a predictor of dietary quality in spouses during midlife. Behav Med. 2008;34(1):5-10.

  34. Bugreev DV, Brosh RM Jr, Mazin AV. RECQ1 possesses DNA branch migration activity. J Biol Chem. 2008;283(29):20231-20242.

  35. Bukowy Z, Harrigan JA, Ramsden DA, Tudek B, Bohr VA, Stevnsner T. WRN exonuclease activity is blocked by specific oxidatively induced base lesions positioned in either DNA strand. Nucleic Acids Res. 2008 July. [Epub ahead of print].

  36. Cai H, Shim H, Lai C, Xie C, Lin X, Yang WJ, Chandran J. LS2/Alsin knockout mice and motor neuron diseases. Neurodegener Dis. 2008; 5(6):359-367.

  37. Camargos ST, Cardoso F, Momeni P, Gurgel Gianetti J, Lees A, Hardy J, Singleton A. Novel GCH1 mutation in a Brazilian family with dopa-responsive dystonia. Mov Disord. 2008;23(2):299-302.

  38. Camargos S, Scholz S, Simon-Sanchez J, Paisan-Ruiz C, Lewis P, Hernandez D, Ding J, Gibbs JR, Cookson MR, Bras J, Guerreiro R, Oliveira CR, Lees A, Hardy J, Cardoso F, Singleton AB. DYT16, a novel young-onset dystonia-parkinsonism disorder: identification of a segregating mutation in the stress-response protein PRKRA. Lancet Neurol. 2008;7(3):207-215.

  39. Cao YJ, Mager DE, Simonsick EM, Hilmer SN, Ling SM, Windham BG, Crentsil V, Yasar S, Fried LP, Abernethy DR. Physical and cognitive performance and burden of anticholinergics, sedatives, and ACE inhibitors in older women. Clin Pharmacol Ther. 2008;83(3):422-429.

  40. Cappola AR, Maggio M, Ferrucci L. Is research on hormones and aging finished? No! Just started! J Gerontol A Biol Sci Med Sci. 2008;63(7):696-698.

  41. Cardoso CL, de Moraes MC, Carvalho Guido RV, Oliva G, Andricopulo AD, Wainer IW, Cass QB. The development of an immobilized enzyme reactor containing glyceraldehyde-3-phosphate dehydrogenase from Trypanosoma cruzi: the effect of species' specific differences on the immobilization. Analyst. 2008;133(1):93-99.

  42. Carter MG, Stagg CA, Falco G, Yoshikawa T, Bassey UC, Aiba K, Sharova LV, Shaik N, Ko MS. An in situ hybridization-based screen for heterogeneously expressed genes in mouse ES cells. Gene Expr Patterns. 2008;8(3):181-198.

  43. Casolaro V, Fang X, Tancowny B, Fan J, Wu F, Srikantan S, Asaki SY, De Fanis U, Huang SK, Gorospe M, Atasoy UX, Stellato C. Posttranscriptional regulation of IL-13 in T cells: Role of the RNA-binding protein HuR. J Allergy Clin Immunol. 2008 Feb.; [Epub ahead of print].

  44. Cecchi F, Mannoni A, Molino-Lova R, Ceppatelli S, Benvenuti E, Bandinelli S, Lauretani F, Macchi C, Ferrucci L. Epidemiology of hip and knee pain in a community based sample of Italian persons aged 65 and older. Osteoarthritis Cartilage. 2008 Mar.; [Epub ahead of print].

  45. Chang YC, Kim HW, Rapoport SI, Rao JS. Chronic NMDA administration increases neuroinflammatory markers in rat frontal cortex: cross-talk between excitotoxicity and neuroinflammation. Neurochem Res. 2008 May. [Epub ahead of print].

  46. Chang YC, Rapoport SI, Rao JS. Chronic administration of mood stabilizers upregulates BDNF and Bcl-2 expression levels in rat frontal cortex. Neurochem Res. 2008 August. [Epub ahead of print].

  47. Chantler PD, Lakatta EG, Najjar SS. Arterial-ventricular coupling: mechanistic insights into cardiovascular performance at rest and during exercise. J Appl Physiol. 2008 July. [Epub ahead of print].

  48. Chantler PD, Melenovsky V, Schulman SP, Gerstenblith G, Becker LC, Ferrucci L, Fleg JL, Lakatta EG, Najjar SS. The sex-specific impact of systolic hypertension and systolic blood pressure on arterial-ventricular coupling at rest and during exercise. Am J Physiol Heart Circ Physiol. 2008;295(1):H145-H-153.

  49. Chen J, Xiao L, Rao JN, Zou T, Liu L, Bellavance E, Gorospe M, Wang JY. JunD represses transcription and translation of the tight junction protein ZO-1 modulating intestinal epithelial barrier function. Mol Biol Cell. 2008 June. [Epub ahead of print].

  50. Chen WM, Erdos MR, Jackson AU, Saxena R, Sanna S, Silver KD, Timpson NJ, Hansen T, Orru M, Grazia Piras M, Bonnycastle LL, Willer CJ, Lyssenko V, Shen H, Kuusisto J, Ebrahim S, Sestu N, Duren WL, Spada MC, Stringham HM, Scott LJ, Olla N, Swift AJ, Najjar S, Mitchell BD, Lawlor DA, Smith GD, Ben-Shlomo Y, Andersen G, Borch-Johnsen K, J�rgensen T, Saramies J, Valle TT, Buchanan TA, Shuldiner AR, Lakatta E, Bergman RN, Uda M, Tuomilehto J, Pedersen O, Cao A, Groop L, Mohlke KL, Laakso M, Schlessinger D, Collins FS, Altshuler D, Abecasis GR, Boehnke M, Scuteri A, Watanabe RM. Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels. J Clin Invest. 2008;118(7)2620-2628.

  51. Cheng WH, Muftic D, Muftuoglu M, Dawut L, Morris C, Helleday T, Shiloh Y, Bohr VA. WRN is required for ATM activation and the S-phase checkpoint in response to interstrand crosslink-induced DNA double strand breaks. Mol Biol Cell. 2008 July. [Epub ahead of print].

  52. Chia CW, Egan JM. Special Features: Incretin-based therapies in type 2 diabetes mellitus. J Clin Endocrinol Metab. 2008 July. [Epub ahead of print].

  53. Chiara F, Castellaro D, Marin O, Petronilli V, Brusilow WS, Juhaszova M, Sollott SJ, Forte M, Bernardi P, Rasola A. Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels. PLoS ONE. 2008;3(3):e1852.

  54. Chigurupati S, Son T, Hyun DH, Lathia J, Mughal M, Savell J, Li S, Ganji N, Chan S, Arumugam T, Mattson M. Lifelong running reduces oxidative stress and degenerative changes in the testes of mice. J Endocrinol. 2008 August. [Epub ahead of print].

  55. Choi JH, Park JT, Davidson B, Morin PJ, Shih IM, Wang TL. Jagged-1 and Notch3 juxtacrine loop regulates ovarian tumor growth and adhesion. Cancer Res. 2008;68(14):5716-5723.

  56. Choi SH, Langenbach R, Bosetti F. Genetic deletion or pharmacological inhibition of cyclooxygenase-1 attenuate lipopolysaccharide-induced inflammatory response and brain injury. FASEB J. 2008;22(5):1491-1501.

  57. Cookson MR, van der Brug M. Cell systems and the toxic mechanism(s) of alpha-synuclein. Exp Neurol. 2008;209(1):5-11.

  58. Csiszar A, Labinskyy N, Podlutsky A, Kaminski PM, Wolin MS, Zhang C, Mukhopadhyay P, Pacher P, Hu F, de Cabo R, Ballabh P, Ungvari Z. Vasoprotective effects of resveratrol and SIRT1: attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations. Am J Physiol Heart Circ Physiol. 2008;294(6):H2721-H2735.

  59. Csiszar A, Wang M, Lakatta EG, Ungvari ZI. Inflammation and endothelial dysfunction during aging: role of NF-{kappa}B. J Appl Physiol. 2008 July. [Epub ahead of print].

  60. Dahiya N, Sherman-Baust CA, Wang TL, Davidson B, Shih IeM, Zhang Y, Wood W 3rd, Becker KG, Morin PJ. MicroRNA expression and identification of putative miRNA targets in ovarian cancer. PLoS ONE. 2008;3(6):e2436.

  61. Davatzikos C, Fan Y, Wu X, Shen D, Resnick SM. Detection of prodromal Alzheimer's disease via pattern classification of magnetic resonance imaging. Neurobiol Aging. 2008;29(4):514-523.

  62. Dawson HD, Collins G, Pyle R, Key M, Taub DD. Retinoic acid receptor-alpha mediates human T-cell activation and Th2 cytokine production. BMC Immunol. 2008 Apr.;9(1):16 [Epub ahead of print].

  63. Dayhoff-Brannigan M, Ferrucci L, Sun K, Fried LP, Walston J, Varadhan R, Guralnik JM, Semba RD. Oxidative protein damage is associated with elevated serum interleukin-6 levels among older moderately to severely disabled women living in the community. J Gerontol A Biol Sci Med Sci. 2008;63(2):179-183.

  64. Dehvari N, Sandebring A, Flores-Morales A, Mateos L, Chuan YC, Goldberg MS, Cookson MR, Cowburn RF, Cedazo-M�nguez A. Parkin-mediated ubiquitination regulates phospholipase C-gamma1. J Cell Mol Med. 2008 July. [Epub ahead of print].

  65. Deng J, Lewis PA, Greggio E, Sluch E, Beilina A, Cookson MR. Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase. Proc Natl Acad Sci USA. 2008;105(5):1499-1504.

  66. Deo R, Wassel Fyr CL, Fried LF, Newman AB, Harris TB, Angleman S, Green C, Kritchevsky SB, Chertow GM, Cummings SR, Shlipak MG; for the Health ABC study. Kidney dysfunction and fatal cardiovascular disease-an association independent of atherosclerotic events: Results from the Health, Aging, and Body Composition (Health ABC) study. Am Heart J. 2008;155(1):62-68.

  67. Deshpande N, Metter EJ, Bandinelli S, Lauretani F, Windham BG, Ferrucci L. Psychological, physical, and sensory correlates of fear of falling and consequent activity restriction in the elderly: The InCHIANTI Study. Am J Phys Med Rehabil. 2008;87(5):354-362.

  68. Deshpande N, Metter EJ, Lauretani F, Bandinelli S, Guralnik J, Ferrucci L. Activity restriction induced by fear of falling and objective and subjective measures of physical function: a prospective cohort study. J Am Geriatr Soc. 2008;56(4):615-620.

  69. Deshpande N, Metter EJ, Ling S, Conwit R, Ferrucci L. Physiological correlates of age-related decline in vibrotactile sensitivity. Neurobiol Aging. 2008;29(5):765-773.

  70. de Souza-Pinto NC, Wilson DM 3rd, Stevnsner TV, Bohr VA. Mitochondrial DNA, base excision repair and neurodegeneration. DNA Repair (Amst). 2008 May. [Epub ahead of print].

  71. Di Bari M, Pecchioli A, Mazzaglia G, Marini M, Maciocco G, Ferrucci L, Marchionni N. Care available to severely disabled older persons living at home in Florence, Italy. Aging Clin Exp Res. 2008;20(1):31-39.

  72. Ding J, Kritchevsky SB, Harris TB, Burke GL, Detrano RC, Szklo M, Jeffrey Carr J; for the Multi-Ethnic Study of Atherosclerosis. The association of pericardial fat with calcified coronary plaque. Obesity (Silver Spring). 2008 May. [Epub ahead of print].

  73. Dotson VM, Kitner-Triolo M, Evans MK, Zonderman AB. Literacy-based normative data for low socioeconomic status African Americans. Clin Neuropsychol. 2008;21:1-29.

  74. Dotson VM, Resnick SM, Zonderman AB. Differential association of concurrent, baseline, and average depressive symptoms with cognitive decline in older adults. Am J Geriatr Psychiatry. 2008;16(4):318-330.

  75. Downs JL, Mattison JA, Ingram DK, Urbanski HF. Effect of age and caloric restriction on circadian adrenal steroid rhythms in rhesus macaques. Neurobiol Aging. 2008;29(9):1412-1422.

  76. Earley CJ, Ponnuru P, Wang X, Patton SM, Conner JR, Beard JL, Taub DD, Allen RP. Altered iron metabolism in lymphocytes from subjects with restless legs syndrome. Sleep. 2008;31(6):847-852.

  77. Ebersole JL, Steffen MJ, Reynolds MA, Branch-Mays GL, Dawson DR, Novak KF, Gunsolley JC, Mattison JA, Ingram DK, Novak MJ. Differential gender effects of a reduced-calorie diet on systemic inflammatory and immune parameters in nonhuman primates. J Periodontal Res. 2008 June. [Epub ahead of print].

  78. Egan JM, Margolskee RF. Taste cells of the gut and gastrointestinal chemosensation. Mol Interv. 2008;8(2):78-81.

  79. Elahi D, Egan JM, Shannon RP, Meneilly GS, Khatri A, Habener JF, Andersen DK. GLP-1 (9-36) amide, cleavage product of GLP-1 (7-36) amide, is a glucoregulatory peptide. Obesity (Silver Spring). 2008 April; [Epub ahead of print].

  80. Esposito G, Giovacchini G, Liow JS, Bhattacharjee AK, Greenstein D, Schapiro M, Hallett M, Herscovitch P, Eckelman WC, Carson RE, Rapoport SI. Imaging neuroinflammation in Alzheimer�s disease with radiolabeled arachidonic acid and PET. J Nucl Med. 2008 August. [Epub ahead of print].

  81. Fan Y, Resnick SM, Wu X, Davatzikos C. Structural and functional biomarkers of prodromal Alzheimer's disease: A high-dimensional pattern classification study. Neuroimage. 2008; [Epub ahead of print].

  82. Farasat SM, Morrell CH, Scuteri A, Ting CT, Yin F, Spurgeon HA, Chen CH, G Lakatta E, Najjar SS. Do hypertensive individuals have enlarged aortic root diameters? Insights from studying the various subtypes of hypertension. Am J Hypertens. 2008;21(5):558-563.

  83. Farasat SM, Morrell CH, Scuteri A, Ting C-T, Yin FCP, Spurgeon HA, Chen C-H, Lakatta EG, Najjar SS. Pulse pressure is inversely related to aortic root diameter: implications for the pathogenesis of systolic hypertension. Hypertension. 2008;51:196-202.

  84. Farias SE, Basselin M, Chang L, Heidenreich KA, Rapoport SI, Murphy RC. Formation of eicosanoids, E2/D2-isoprostanes and docosanoids following decapitation-induced ischemia, measured in high-energy microwaved rat brain. J Lipid Res. 2008 May. [Epub ahead of print].

  85. Ferrucci L. Throwing pots and commitments for 2008. J Gerontol A Biol Sci Med Sci. 2008;63(2):157-159.

  86. Firestein R, Blander G, Michan S, Oberdoerffer P, Ogino S, Campbell J, Bhimavarapu A, Luikenhuis S, de Cabo R, Fuchs C, Hahn WC, Guarente LP, Sinclair DA. The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth. PLoS ONE. 2008;3(4):e2020.

  87. Fleg JL and Lakatta EG. Normal Aging of the Cardiovascular System. Chapter in Cardiovascular Disease in the Elderly. Fourth edition. Wilbert Aronow, Michael W. Rich, Jerome L. Fleg, eds. CRC Press, Boca Raton, Florida. 2008:1-43.

  88. Freathy RM, Timpson NJ, Lawlor DA, Pouta A, Ben-Shlomo Y, Ruokonen A, Ebrahim S, Shields B, Zeggini E, Weedon MN, Lindgren CM, Lango H, Melzer D, Ferrucci L, Paolisso G, Neville MJ, Karpe F, Palmer CN, Morris AD, Elliott P, Jarvelin MR, Smith GD, McCarthy MI, Hattersley AT, Frayling TM. Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected, given its effect on BMI. Diabetes. 2008 Mar.; [Epub ahead of print].

  89. Furey ML, Ricciardi E, Schapiro MB, Rapoport SI, Pietrini P. Cholinergic enhancement eliminates modulation of neural activity by task difficulty in the prefrontal cortex during working memory. J Cogn Neurosci. 2008 Feb.; [Epub ahead of print].

  90. Galban S, Kuwano Y, Pullmann R Jr, Martindale JL, Kim HH, Lal A, Abdelmohsen K, Yang X, Dang Y, Liu JO, Lewis SM, Holcik M, Gorospe M. RNA-binding proteins HuR and PTB promote the translation of hypoxia-inducible factor-1{alpha} Mol Cell Biol. 2008;28(1):93-107.

  91. Gearhart PJ. Response to �Mutation frequency vs. mutation patterns: A comparison of the results in spleen and Peyer�s patches� DNA Repair (Amst). 2008 July. [Epub ahead of print].

  92. Giles JT, Ling SM, Ferrucci L, Bartlett SJ, Andersen RE, Towns M, Muller D, Fontaine KR, Bathon JM. Abnormal body composition phenotypes in older rheumatoid arthritis patients: Association with disease characteristics and pharmacotherapies. Arthritis Rheum. 2008;59(6):807-815.

  93. Goldman SE, Hall M, Boudreau R, Matthews KA, Cauley JA, Ancoli-Lsrael S, Stone KL, Rubin SM, Satterfield S, Simonsick EM, Newman AB. Association between nighttime sleep and napping in older adults. Sleep. 2008;31(5):733-740.

  94. Gong F, Fahy D, Liu H, Wang W, Smerdon MJ. Role of the mammalian SWI/SNF chromatin remodeling complex in the cellular response to UV damage. Cell Cycle. 2008;7(8). [Epub ahead of print].

  95. Gorospe M, de Cabo R. AsSIRTing the DNA damage response. Trends Cell Biol. 2008;18(2):77-83.

  96. Gouras P, Ivert L, Landauer N, Mattison JA, Ingram DK, Neuringer M. Drusenoid maculopathy in rhesus monkeys (Macaca mulatta): effects of age and gender. Graefes Arch Clin Exp Ophthalmol. 2008 August. [Epub ahead of print].

  97. Gouras P, Ivert L, Mattison JA, Ingram DK, Neuringer M. Drusenoid maculopathy in rhesus monkeys: autofluorescence, lipofuscin and drusen pathogenesis. Graefes Arch Clin Exp Ophthalmol. 2008 August. [Epub ahead of print].

  98. Gredilla R, Garm C, Holm R, Bohr VA, Stevnsner T. Differential age-related changes in mitochondrial DNA repair activities in mouse brain regions. Neurobiol Aging. 2008 August. [Epub ahead of print].

  99. Greggio E, Zambrano I, Kaganovich A, Beilina A, Taymans JM, Dani�ls V, Lewis P, Jain S, Ding J, Syed A, Thomas KJ, Baekelandt V, Cookson MR. The Parkinson disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylation. J Biol Chem. 2008;283(24):16906-16914.

  100. Grober E, Hall CB, Lipton RB, Zonderman AB, Resnick SM, Kawas C. Memory impairment, executive dysfunction, and intellectual decline in preclinical Alzheimer's disease. J Int Neuropsychol Soc. 2008;14(2):266-278.

  101. Guerreiro RJ, Baquero M, Blesa R, Boada M, Br�s JM, Bullido MJ, Calado A, Crook R, Ferreira C, Frank A, G�mez-Isla T, Hern�ndez I, Lle� A, Machado A, Mart�nez-Lage P, Masdeu J, Molina-Porcel L, Molinuevo JL, Pastor P, P�rez-Tur J, Relvas R, Oliveira CR, Ribeiro MH, Rogaeva E, Sa A, Samaranch L, S�nchez-Valle R, Santana I, T�rraga L, Valdivieso F, Singleton A, Hardy J, Clarim�n J. Genetic screening of Alzheimer�s disease genes in Iberian and African samples yields novel mutations in presenilins and APP. Neurobiol Aging. 2008 July. [Epub ahead of print].

  102. Guerreiro RJ, Santana I, Bras JM, Revesz T, Rebelo O, Ribeiro MH, Santiago B, Oliveira CR, Singleton A, Hardy J. Novel progranulin mutation: Screening for PGRN mutations in a Portuguese series of FTD/CBS cases. Mov Disord. 2008 May. [Epub ahead of print].

  103. Guerreiro RJ, Schymick JC, Crews C, Singleton A, Hardy J, Traynor BJ. TDP-43 is not a common cause of sporadic amyotrophic lateral sclerosis. PLoS ONE. 2008;3(6):e2450.

  104. Guilarte TR, Burton NC, Verina T, Prabhu VV, Becker KG, Syversen T, Schneider JS. Increased APLP1 expression and neurodegeneration in the frontal cortex of manganese-exposed non-human primates. J Neurochem. 2008 Feb.; [Epub ahead of print].

  105. Gupta R, Brosh RM Jr. Helicases as prospective targets for anti-cancer therapy. Anticancer Agents Med Chem. 2008;8(4):390-401.

  106. Guralnik JM. Successful aging: is it in our future? Arch Intern Med. 2008;168(2):131-132.

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