What's New From the USPSTF

Screening for Abdominal Aortic Aneurysm


This series of fact sheets is based on the work of the U.S. Preventive Services Task Force (USPSTF). The USPSTF systematically reviews the evidence of effectiveness of a wide range of clinical preventive services—including screening, counseling, and chemoprevention (the use of medication to prevent diseases)—to develop recommendations for preventive care in the primary care setting.

This fact sheet presents highlights of USPSTF recommendations on this topic and should not be used to make treatment or policy decisions.


What Does the U.S. Preventive Services Task Force Recommend?

The U.S. Preventive Services Task Force (USPSTF) recommends one-time screening for abdominal aortic aneurysm by abdominal ultrasonography for men between the ages of 65 and 75 who have ever smoked (i.e., at least 100 cigarettes during one's lifetime). The USPSTF makes no recommendation for or against screening for abdominal aortic aneurysm in men between the ages of 65 and 75 who have never smoked. The USPSTF recommends against routine screening for abdominal aortic aneurysm in women.

What Are the Risk Factors?

Being male, 65 or older, and ever having smoked are the major risk factors for abdominal aortic aneurysm. A first-degree family history of abdominal aortic aneurysm requiring surgical repair also elevates a man's risk for this condition; this may also be true for women but the evidence is less certain.

The U.S. Preventive Services Task Force recommends one-time screening for abdominal aortic aneurysm by abdominal ultrasonography for men between the ages of 65 and 75 who have ever smoked.

What Are the Potential Benefits of Screening and Treatment?

Screening for abdominal aortic aneurysm and open surgical repair of abdominal aortic aneurysms of 5.5 cm or more in older men leads to an estimated 43-percent reduction in mortality from abdominal aortic aneurysm. In men with abdominal aortic aneurysms of 4.0 to 5.4 cm, periodic surveillance, combined with elective surgery in those whose abdominal aortic aneurysm has progressed, offers comparable mortality benefit to routine elective surgery. Currently, there is no evidence to support any intervention in those with small abdominal aortic aneurysms (3.0-3.9 cm), although some expert opinion-based recommendations favor annual ultrasonography for these patients.

The potential benefit of screening for abdominal aortic aneurysm among women aged 65 to 75 is low due to the small number of deaths related to this condition in this population. A clinician may, however, choose to discuss screening in unusual circumstances, such as in the case of a healthy female smoker in her early 70s who has a first-degree family history for abdominal aortic aneurysm that required surgery.

One-time screening using ultrasonography is sufficient to detect abdominal aortic aneurysm, since new abdominal aortic aneurysm is extremely rare in persons with an initial negative result. Abdominal ultrasonography is an accurate screening test for abdominal aortic aneurysm if it is performed in a setting with adequate quality assurance (i.e., an accredited facility with credentialed technologists). Screening for abdominal aortic aneurysm should be reserved for those who have a reasonable probability of having an abdominal aortic aneurysm large enough to benefit from surgery and for those who have a reasonable life expectancy.

Screening should be reserved for those who have a reasonable probability of having an abdominal aortic aneurysm large enough to benefit from surgery and for those who have a reasonable life expectancy.

What Are the Harms of Screening and Treatment?

The peri-operative mortality for open surgical repair of abdominal aortic aneurysm is 4% to 5%. Nearly one-third of patients who undergo surgery for abdominal aortic aneurysm have important complications, such as cardiac and pulmonary conditions. Men who undergo this surgery are at increased risk for impotence.

Endovascular repair (EVAR) of abdominal aortic aneurysm is being used as an alternative to open surgical repair. Recent studies have shown a short-term mortality and morbidity benefit of EVAR compared with open surgical repair. The long-term effectiveness of EVAR to reduce abdominal aortic aneurysm rupture and mortality is still being studied.

More Information

For more information, go to:

healthfinder®
www.healthfinder.gov

National Institutes of Health
www.nih.gov

More detailed information on this subject is available in "Primary Care Screening for Abdominal Aortic Aneurysm: Evidence Synthesis," in the USPSTF recommendation statement, and in the cost-effectiveness analyses review. All can be found on the Agency for Healthcare Research and Quality (AHRQ) Web site (http://www.preventiveservices.ahrq.gov) and through the National Guideline Clearinghouse (http://www.guideline.gov).

USPSTF Members

Members of the USPSTF represent the fields of family medicine, gerontology, obstetrics-gynecology, pediatrics, nursing, prevention research, and psychology. Members of the USPSTF when its recommendation on this topic was finalized:

Ned Calonge, M.D., M.P.H., Chair
Janet D. Allan, Ph.D., R.N., CS, Vice-chair
Alfred O. Berg, M.D., M.P.H.
Paul S. Frame, M.D.
Leon Gordis, M.D., M.P.H., Dr.P.H.
Kimberly D. Gregory, M.D., M.P.H.
Russell Harris, M.D., M.P.H.
Mark S. Johnson, M.D., M.P.H.
Jonathan D. Klein, M.D., M.P.H.
Carol Loveland-Cherry, Ph.D., R.N.
Virginia A. Moyer, M.D., M.P.H.
Judith K. Ockene, Ph.D.
Diana B. Petitti, M.D., M.P.H.
Albert L. Siu, M.D., M.S.P.H.
Steven M. Teutsch, M.D., M.P.H.
Barbara P. Yawn, M.D., M.Sc.

For a list of current Task Force members, go to www.ahrq.gov/clinic/uspstfab.htm.

AHRQ Publication No. 05-IP002
Current as of February 2005


Internet Citation:

Screening for Abdominal Aortic Aneurysm: What's New From the USPSTF? AHRQ Publication No. 05-IP002, February 2005. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/clinic/uspstf05/aaascr/aaawh.htm


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