Agency for Toxic Substances and Disease Registry
 
CONTENTS
Toxicological Profile Information
Toxicological Profile Access

Toxicological Profile Contents
Preface
Relevance to Public Health
Health Effects
Chemical and Physical Information
Production, Import, Use, and Disposal
Potential for Human Exposure
Analytical Methods
Regulations and Advisories
References
Glossary
Appendices

Reference
Disclaimer
Where can I get more information?
RELATED RESOURCES
ToxFAQ PDF File for Uranium ToxFAQ™ (File Size 40k)40k
ToxFAQ™ en Español PDF File for Uranium ToxFAQ™ en Español (File Size 31k)31k
Public Health Statement PDF File for Uranium Public Health Statement (File Size 150k)150k
Toxicological Profile PDF File for Uranium Toxicological Profile (File Size 6.8MB)6.8MB
A-Z INDEX
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L M N O P
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VX Y Z
ATSDR RESOURCES
ToxFAQs
ToxFAQs™ en Español
Public Health Statements
Toxicological Profiles
Minimum Risk Levels
MMGs
MHMIs
Interaction Profiles
Priority List of Hazardous Substances
Division of Toxicology

September 1999
Toxicological Profile
for
Uranium
 
CAS# 7440-61-1

Toxicological Profile Information

The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects information for the hazardous substance described here. Each peer-reviewed profile identifies and reviews the key literature that describes a hazardous substance's toxicologic properties. Other pertinent literature is also presented, but is described in less detail than the key studies. The complete list of topics covered (chapter titles) is shown at the left and in more detail further down this page.

The focus of the profile is on health and toxicologic information. Therefore, each profile begins with a Public Health Statement that summarizes in nontechnical language, a substance's relevant properties.

A useful two page information sheet, the ToxFAQs, is also available.

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Toxicological Profile Access

In order to access the ATSDR toxicological profiles' PDF files below, you must have Adobe Acrobat Reader .

You may download that program for free from this link to Adobe  Exiting the ATSDR Web Site.  and then use it to access (open) the files below that are labeled as PDF files.

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Toxicological Profile Contents

The table of contents and list of individual PDF files are given below. The whole profile in one large PDF file is here: PDF File for the Uranium Toxicological Profile (File Size 6.8MB) 6.8MB

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Preface PDF File for Preface Chapter of Uranium Toxicological Profile (File Size 213k) 213k
Foreword
Contributors
Peer review
Contents
List of figures
List of tables
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1. Public Health Statement PDF File for Chapter 1 - Public Health Statement of Uranium Toxicological Profile (File Size 150k) 150k
1.1 What is this substance?
1.2 What happens to it when it enters the environment?
1.3 How might I be exposed to it?
1.4 How can it enter and leave my body?
1.5 How can it affect my health?
1.6 Is there a medical test to determine whether I have
been exposed to it?
1.7 What recommendations has the federal government
made to protect human health?
1.8 Where can I get more information?
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2. Health Effects PDF File for Chapter 2 - Health Effects of Uranium Toxicological Profile (File Size 3.9MB) 3.9MB
2.1 Introduction
2.2 Discussion of health effects by route of exposure
2.3 Toxicokinetics
2.4 Mechanisms of action
2.5 Relevance to public health
2.6 Biomarkers of exposure and effect
2.7 Interactions with other substances
2.8 Populations that are unusually susceptible
2.9 Methods for reducing toxic effects
2.10 Adequacy of the database
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3. Chemical and Physical Information PDF File for Chapter 3 - Chemical and Physical Information of Uranium Toxicological Profile (File Size 390k) 390k
3.1 Chemical Identity
3.2 Physical and Chemical Properties
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4. Production, Import, Use, and Disposal PDF File for Chapter 4 - Production, Import, Use, and Disposal of Uranium Toxicological Profile (File Size 403k) 403k
4.1 Production
4.2 Import / Export
4.3 Use
4.4 Disposal
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5. Potential for Human Exposure PDF File for Chapter 5 - Production, Import, Use, and Disposal of Uranium Toxicological Profile (File Size 825k) 825k
5.1 Overview
5.2 Releases to the environment
5.3 Environmental fate
5.4 Levels monitored or estimated in the environment
5.5 General population and occupational exposure
5.6 Populations with potentially high exposure
5.7 Adequacy of the database
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6. Analytical Methods PDF File for Chapter 6 - Production, Import, Use, and Disposal of Uranium Toxicological Profile (File Size 735k) 735k
6.1 Biological materials
6.2 Environmental samples
6.3 Adequacy of the database
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7. Regulations and Advisories PDF File for Chapter 7 - Production, Import, Use, and Disposal of Uranium Toxicological Profile (File Size 651k) 651k
 
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8. References PDF File for Chapter 8 - Production, Import, Use, and Disposal of Uranium Toxicological Profile (File Size 230k) 230k

 

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9. Glossary PDF File for Chapter 9 - Production, Import, Use, and Disposal of Uranium Toxicological Profile (File Size 229k) 229k

 

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Appendices PDF File for the Appendices Chapter of Uranium Toxicological Profile (File Size 338k) 338k
A. Minimal risk level worksheets
B. User's guide
C. Acronyms, abbreviations, and symbols
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Reference

Agency for Toxic Substances and Disease Registry (ATSDR). 1999. Toxicological profile for uranium. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service.

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Disclaimer

All ATSDR toxicological profile PDF files are electronic conversions from paper copy or other electronic ASCII text files. This conversion may have resulted in character translation or format errors. Users are referred to the original paper copy of the toxicological profile for the official text, figures, and tables. Original paper copies can be obtained via the directions on the toxicological profile home page, which also contains other important information about the profiles.

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Where can I get more information?

ATSDR can tell you where to find occupational and environmental health clinics. Their specialists can recognize, evaluate, and treat illnesses resulting from exposure to hazardous substances. You can also contact your community or state health or environmental quality department if you have any more questions or concerns.

For more information, contact:

Agency for Toxic Substances and Disease Registry
Division of Toxicology
1600 Clifton Road NE, Mailstop F-32
Atlanta, GA 30333
Phone: 1-888-42-ATSDR (1-888-422-8737)
FAX:   (770)-488-4178
Email: ATSDRIC@cdc.gov

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ATSDR Information Center / ATSDRIC@cdc.gov / 1-888-422-8737

This page was updated on 08/28/2008