Optical Imaging

Congwu Du, a Biomedical Engineering researcher at Brookhaven.

Dr. Congwu Du has developed a catheter-based optical system capable of measuring changes in the concentration and oxidation states of hemoglobin, concurrently with calcium Rhod2 fluorescence in the living brain. The optical instrument comprises a 150-W xenon lamp, a fast excitation monochromator and photo-counting detectors for fluorescence and diffusion reflectance. The xenon lamp is connected to a computer-controlled monochromator to select incident lights of 548, 555 and 572 nm by time-sharing to sequentially deliver the selected light onto the brain surface through one arm of a Y-shaped bifurcated fiber optic bundle. The first data testing the instrument capabilities in a stroke model has recently been published.

Last Modified: January 31, 2008

One of ten national laboratories overseen and primarily funded by the Office of Science of the U.S. Department of Energy (DOE), Brookhaven National Laboratory conducts research in the physical, biomedical, and environmental sciences, as well as in energy technologies and national security. Brookhaven Lab also builds and operates major scientific facilities available to university, industry and government researchers. Brookhaven is operated and managed for DOE’s Office of Science by Brookhaven Science Associates, a limited-liability company founded by Stony Brook University, the largest academic user of Laboratory facilities, and Battelle, a nonprofit, applied science and technology organization.

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