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Cover Design for NISTIR 7350 includes an image for LED and OLED and an image depicting an operating room.

Trends and Opportunities in Photonics Technologies: Solid-State Lighting and Healthcare

NISTIR 7305

Grady S. White
Kris A. Bertness

May 2006

View Adobe PDF version of interim report.

TABLE OF CONTENTS

I.  INTRODUCTION

II. SOLID-STATE LIGHTING (SSL)

A.  Current Status 

B.  White Light Generation

  1. Blue light source with fluorescing particles
  2. UV LED with fluorescing particles
  3. Three Color LEDs/OLEDs

C. Scientific and Technical Barriers

  1. 1 - 3 year time frame
  2. 5 - 10 year time frame
  3. Additional considerations 

D. NIST Interaction Opportunities in SSL

1.  DOE

  1. NIST Laboratories
  2. ATP

2.  NEMA

  1. NIST Laboratories
  2. ATP

3.  Next Generation Lighting Industry Alliance

  1. NIST Laboratories
  2. ATP

4.  OIDA 

  1. NIST Laboratories
  2. ATP

E.  NIST Laboratory Research Opportunities

  1. Inorganic devices 
  2. Organic specific 

III. PHOTONICS IN HEALTHCARE 

A.  Current Status

  1. Clinical 
  2. Research and development
a)  In vitro
      i. Optical microscopy
      ii. Spectroscopy 
      iii. Combinatorial approaches
b) In vivo
      i. Imaging
      ii. Diagnostics
      iii. Treatment

B.  Long-term issues

  1. Implant/biomarker issues
  2. Imaging/spectroscopy

C.  NIST Interaction Opportunities in Photonics in Healthcare
1.  Food and Drug Administration

  1. NIST Laboratories
  2. ATP

2.  National Institutes of Health

  1. NIST Laboratories
  2. ATP

3.  National Science Foundation

  1. NIST Laboratories
  2. ATP

D.  NIST Research Opportunities

IV.  REFERENCES

V.  APPENDIX I: NIST staff sources for this report

VI. APPENDIX II: Non-NIST sources

VII. APPENDIX III: ATP-funded projects

VIII. APPENDIX IV: Benefits accrued to ATP detail

TABLES and FIGURES
Table 1: Sector and CRI estimates of teralumen-hours lighting demand in 2005
Table 2: Typical efficacies of LEDs/OLEDs in 1999
Table 3: Strengths and weaknesses of current optical techniques (Healthcare)
Figure 1: Three approaches to generate a solid state white lamp
Figure 2a: Scientific and technical barriers to LEDs
Figure 2b: Scientific and technical barriers to OLEDs
Figure 3: Confocal microscope schematic
Figure 4: Two-photon energy schematic
Figure 5: Higher harmonic generation
Figure 6: Fluorescent resonant energy transfer schematic
Figure 7: Total internal reflections schematic
Figure 8: Flowchart showing sequential, semi-independent relationship between diagnosis, treatment, and treatment evaluation in current medical practice
Figure 9: Penetration depth through water and hemoglobin across the visible  wavelength range
Figure 10: Schematic of future use of photonics in medical care

Go to Section 1. Introduction.

Date created: May 24, 2006
Last updated: June 9, 2006

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