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Mechanistic Studies of Cardiovascular Effects of Botanicals
August 22-23, 2002
Bethesda, Maryland
Sponsored by:
National Heart, Lung, and Blood Institute
NIH Office of Dietary Supplements
National Center for Complementary and Alternative Medicine
DRAFT AGENDA
Note: Registration is required.
Thursday - August 22 (8:30 a.m. - 6:00 p.m.) |
|
| 8:00 a.m. | Coffee |
| 8:30 a.m. | Welcome Claude Lenfant, Director, NHLBI Michael C. Lin, Coordinator, NHLBI |
| 8:40 a.m. | Botanical Medicine: Bridging the Gulf between Promise and Proof Linda Engel, Acting Director Division of Extramural Research and Training, NCCAM NIH Perspectives on Dietary Supplements Paul Coates, Director, ODS |
| 9:10 a.m. |
Development of Botanical Drugs: Regulatory Perspectives on Early Phase Studies Shaw Chen, U.S. Food and Drug Administration |
| Session I 9:40 a.m. | Garlic Chair: Eric Block, State University of New York at Albany |
| Introduction and Overview of the Chemistry and Medicinal Properties of Garlic Eric Block, State University of New York at Albany |
|
| 10:10 a.m. | Mechanisms of Cardiovascular Effects of Garlic Larry Lawson, Plant Bioactives Research Institute |
| 10:40 a.m. | Coffee Break | 11:00 a.m. | Effect of Garlic on Biosynthesis and Serum Levels of Cholesterol and Lipids Rolf Gebhardt, University of Leipzig, Germany |
| 11:30 a.m. | Effect of Garlic on Arteriosclerosis Gunter Siegel, Free University of Berlin, Germany |
| 12:00 p.m. | Discussion |
| 12:30 p.m. | Lunch Break |
| 1:30 p.m. | Effect of Garlic in Experimental Animal Models Jose Pedraza-Chaverri, National University of Mexico, Mexico |
| 2:00 p.m. | Effect of Garlic Powder Tablets on Atherosclerosis Alexander N. Orekhov, Moskow State University, Russia |
| 2:30 p.m. | Clinical Trials: Efect of Garlic Preparations on Cardiovascular Disease and Its Risk Factors Christopher Gardner, Stanford University |
| 3:00 p.m. | Herbal Interactions with Cardiovascular Drugs Adriane Fugh-Berman, George Washington University |
| 3:30 p.m. | Effect of Steam-distilled Garlic Oil on Cardiovascular Disease David Maslin, University of Wolverhampton, UK |
| 3:45 p.m. | Discussion |
| 4:05 p.m. | Coffee Break |
| Session II 4:20 p.m. | Ginkgo Biloba Chair: Curt D. Furberg, Wake Forest University |
| 4:30 p.m. | Vascular Effects of Ginkgo Biloba: Pre-clinical Studies John Farquhar, Stanford University |
| 5:00 p.m. | Efficacy of Ginkgo Biloba in the Treatment and Prevention of Cerebrovascular Disease and Cognitive Impairment: The GEM Study Jeff Williamson, Wake Forest University |
| 5:30 p.m. | Discussion |
Friday - August 23 (8:30 a.m. - 12:30 p.m.) |
|
| 8:00 a.m. | Coffee |
| Session III 8:30 a.m. |
Flavonoid-containing Botanicals Chair: Curt D. Furberg, Wake Forest University |
| 8:40 a.m. | Cardiovascular Protection: The Role of Alcohol and Red Wine Polyphenols Dale Parks, University of Alabama at Birmingham |
| 9:10 a.m. | Hawthorn Extract for Congestive Heart Failure: Pre-clinical and Clinical Studies Keith Aaronson, University of Michigan |
| 9:40 a.m. | Discussion |
| 10:10 a.m. | Cardiovascular Effect of Soy Phytoestrogen: Pre-clinical Studies Thomas Clarkson, Wake Forest University |
| 10:40 a.m. | Coffee Break |
| 11:00 a.m. | Clinical Studies of the Cardiovascular Effects of Phytoestrogens Greg Burke, Wake Forest University |
| 11:30 a.m. | Discussion |
| 12:00 p.m. | Conclusion & Recommendations |
| 12:30 p.m. | Luncheon (optional) |
