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Sponsored by: |
National Taiwan University Hospital |
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Information provided by: | National Taiwan University Hospital |
ClinicalTrials.gov Identifier: | NCT00172458 |
Vertebral artery stenosis (VAS) decreases posterior brain perfusion, causing vertebrobasilar insufficiency (VBI). It is also an important embolic source to the posterior brain. The most frequently involved location is the proximal part of the vessel, including the ostium. Various surgical procedures have been described for the treatment of proximal VAS with symptoms refractory to medical therapy, but all are technically difficult with high operative mortality and morbidity.
Endovascular intervention has been described as an alternative to surgery. Balloon angioplasty is limited by elastic recoil and dissection. The restenosis rates reported in the literature varied, as high as 75 %. Stenting offers salvage following unsuccessful balloon angioplasty, and primary stenting have been shown to be safe and effective with lower restenosis rate. Coronary equipments are ideal for ostial VAS, considering the size of the artery and location of the lesion. Recently, Albuquerque et al. reports a relative high restenosis rate in a longer follow-up duration. Restenosis seems to become an important issue regarding the patients’ quality of life. However, there is no clinical parameter to predict restenosis of VAS. The purpose of this study is to evaluate the clinical results of our series of symptomatic ostial VAS treated exclusively with tubular balloon expandable coronary stents. We sought to identify predictors of restenosis.
This is a clinical observation study. Only chart review and angiographic review will be performed.
Condition |
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Vertebral Artery Stenosis |
Study Type: | Observational |
Study Design: | Natural History, Longitudinal, Defined Population, Retrospective Study |
Official Title: | Clinical Results and Restenosis Analysis of Symptomatic Ostial Vertebral Artery Stenosis Treated With Tubular Coronary Stents |
Genders Eligible for Study: | Both |
Inclusion Criteria:
Patients with symptomatic vertebral artery stenosis treated by stenting
Exclusion Criteria:
-
Contact: Hesien-Li Kao, MD | 886-2-23123456 ext 5874 | hsienlie_kao@yahoo.com |
Taiwan | |
National Taiwan University Hospital | Recruiting |
Taipei, Taiwan | |
Contact: Hesien-Li Kao, MD 886-2-23123456 ext 5874 hsienlie_kao@yahoo.com |
Principal Investigator: | Hesien-Li Kao, MD | National Taiwan University Hospital |
Study ID Numbers: | 9361700454 |
Study First Received: | September 12, 2005 |
Last Updated: | September 14, 2005 |
ClinicalTrials.gov Identifier: | NCT00172458 |
Health Authority: | Taiwan: Department of Health |
Pathological Conditions, Anatomical Vascular Diseases Central Nervous System Diseases Brain Ischemia Constriction, Pathologic |
Ischemia Brain Diseases Cerebrovascular Disorders Vertebrobasilar Insufficiency |
Nervous System Diseases Cardiovascular Diseases |