The Study of Relationship of Plasma Concentrations of Folic Acid, Vitamin B and Homocysteine With Carotid Atherosclerosis and Endothelium-Dependent Vasodilatation of Geriatric and Young Patients in the Ambulatory Care Department of NTUH

This study has been completed.

Sponsored by:	National Taiwan University Hospital
Information provided by:	National Taiwan University Hospital
ClinicalTrials.gov Identifier:	NCT00172250

Purpose

Elevation of plasma homocysteine has been recognized as one of the risk factors of atherosclerotic disease. The objectives of this study are: (1) to investigate the level of plasma homocysteine and the prevalence of hypehomocysteinemia (2) to find out the role of homocysteine in coronary artery disease and the proper cut-off point of plasma homocysteine to evaluate the presence of coronary artery disease; (3) to understand the control condition of tranditional risk factors of cardiovascular disease, especially hypertension, dyslipidemia, and diabetes mellitus.

The study subjects were recruited from the ambulatory setting of cardiology in National Taiwan University Hospital.

Condition
Homocysteine Coronary Artery Disease

MedlinePlus related topics: Coronary Artery Disease

Drug Information available for: Folic acid Homocysteine

U.S. FDA Resources

Study Type:	Observational
Study Design:	Screening, Cross-Sectional, Case Control, Retrospective Study

Further study details as provided by National Taiwan University Hospital:

Study Start Date:

September 2003

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both

Criteria

Inclusion Criteria:

Patient > 65 y/o or < 50y/o Scr<=1.5mg/dL

Exclusion Criteria:

Scr> 1.5mg/dl pregnancy alcohoism

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00172250

Sponsors and Collaborators

National Taiwan University Hospital

Investigators

Principal Investigator:

Juey-Jen Hwang, MD, PhD

National Taiwan University Hospital

More Information

Study ID Numbers:	9261701046
Study First Received:	September 12, 2005
Last Updated:	November 23, 2005
ClinicalTrials.gov Identifier:	NCT00172250
Health Authority:	Taiwan: Department of Health

Study placed in the following topic categories:

Atherosclerosis
Arterial Occlusive Diseases
Heart Diseases
Myocardial Ischemia
Vascular Diseases
Central Nervous System Diseases
Ischemia

Arteriosclerosis
Brain Diseases
Cerebrovascular Disorders
Folic Acid
Coronary Disease
Carotid Artery Diseases
Coronary Artery Disease

Additional relevant MeSH terms:

Nervous System Diseases
Cardiovascular Diseases

ClinicalTrials.gov processed this record on January 16, 2009