Analysis of Clinical Profiles of Chinese Patients With Normal Tension Glaucoma - Full Text View

Analysis of Clinical Profiles of Chinese Patients With Normal Tension Glaucoma

This study is currently recruiting participants.
Verified by Chinese University of Hong Kong, May 2008

Sponsors and Collaborators:	Chinese University of Hong Kong Hong Kong Eye Hospital Prince of Wales Hospital, Shatin, Hong Kong
Information provided by:	Chinese University of Hong Kong
ClinicalTrials.gov Identifier:	NCT00321386

Purpose

To obtain demographic and baseline ophthalmic parameters (such as Intraocular Pressure profiles, disc morphological characteristics, central corneal thickness, peripapillary retinal nerve fibre layer thickness and its serial changes, visual field changes, severity of any medical associations—e.g. hypertension, migraine, strokes) with non-invasive measurements, in Chinese Patients with Normal Tension Glaucoma

Condition

Glaucoma

Genetics Home Reference related topics:

early-onset glaucoma

MedlinePlus related topics:

Glaucoma

U.S. FDA Resources

Study Type:	Observational
Study Design:	Cohort, Prospective

Official Title:	Parameters for Disease Progression in Chinese Patients With Normal Tension Glaucoma

Further study details as provided by Chinese University of Hong Kong:

Biospecimen Retention: Samples With DNA

Biospecimen Description:

Blood taking for glaucoma genetics analysis shall be performed.

Estimated Enrollment:	500
Study Start Date:	December 2003
Estimated Study Completion Date:	December 2009
Estimated Primary Completion Date:	December 2008 (Final data collection date for primary outcome measure)

Show Detailed Description

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes
Sampling Method:	Non-Probability Sample

Study Population

Patients with Normal Tension Glaucoma recruited from a teritary University Eye Hospital setting.

Criteria

Inclusion Criteria:

All Chinese patients with age>18 years old with Normal Tension Glaucoma will be recruited

Exclusion Criteria:

Diseases that precluded accurate measurement of IOP, visual acuity, retinal nerve fiber layer thickness, and visual field tests.
Previous ocular surgery per se is not an exclusion criteria.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00321386

Contacts


Contact: LEUNG YL Dexter, MBChB, FRCS	852-27623000	dexleung@alumni.cuhk.net

Locations


Hong Kong
	Hong Kong Eye Hospital	Recruiting
	Hong Kong, Hong Kong
	Contact: LEUNG YL Dexter, MBChB, FRCS 852-27623000 dexleung@alumni.cuhk.net
	Sub-Investigator: THAM CY Clement, MA, MD, FRCS
	Prince of Wales Hospital	Recruiting
	Hong Kong, Hong Kong

Sponsors and Collaborators

Chinese University of Hong Kong

Hong Kong Eye Hospital

Prince of Wales Hospital, Shatin, Hong Kong

Investigators


Principal Investigator:	LEUNG YL Dexter, MBChB, FRCS	Glaucoma Service, Hong Kong Eye Hospital

Study Chair:	LAM SC Dennis, MD, FRCOphth	Chinese University of Hong Kong

More Information

Publications:

Drance S, Anderson DR, Schulzer M; Collaborative Normal-Tension Glaucoma Study Group. Risk factors for progression of visual field abnormalities in normal-tension glaucoma. Am J Ophthalmol. 2001 Jun;131(6):699-708.

Responsible Party:	Department of Ophthalmology & Visual Sciences, The Chinese University of HK ( Dr. Dexter Leung/ Honorary Clinical Assistant Professor )
Study ID Numbers:	KC/KE 05-0169/ER-1, CRE-2005.434
First Received:	May 1, 2006
Last Updated:	May 13, 2008
ClinicalTrials.gov Identifier:	NCT00321386
Health Authority:	Hong Kong: Ethics Committee

Keywords provided by Chinese University of Hong Kong:

Glaucoma

Open Angle

Normal Tension

Study placed in the following topic categories:

Glaucoma

Eye Diseases

Disease Progression

Hypertension

Ocular Hypertension

ClinicalTrials.gov processed this record on November 06, 2008