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Sponsors and Collaborators: |
Scottsdale Healthcare University of California, Los Angeles University of Colorado at Denver and Health Sciences Center Department of Veterans Affairs University of Kansas |
Information provided by: | Scottsdale Healthcare |
ClinicalTrials.gov Identifier: | NCT00607425 |
This is a pilot study to test the feasibility of using gene expression from saliva to identify patients with early-stage non-small cell lung cancer (NSCLC).
The primary objective of this study is to compare gene expression profiles from saliva from healthy controls and patients with early-stage non-small cell lung cancer.
To be eligible, patients with non-small cell lung cancer, must not yet have received treatment for their cancer (surgical removal, chemotherapy, or radiation therapy). Health control participants may participate if they meet eligibility criteria listed below.
Eligible enrollees will be asked to submit a one time saliva sample and complete a study questionaire.
Condition |
Non-Small Cell Lung Cancer |
MedlinePlus related topics: | Cancer Lung Cancer |
Study Type: | Observational |
Study Design: | Case Control, Other |
Official Title: | Saliva mRNA Expression Profiling for Early Stage Non-Small Cell Lung Cancer Screening |
Saliva
Enrollment: | 40 |
Study Start Date: | August 2007 |
Study Completion Date: | July 2008 |
Primary Completion Date: | July 2008 (Final data collection date for primary outcome measure) |
Groups/Cohorts |
1
Non-small cell lung cancer patients
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2
Healthy control subjects
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Ages Eligible for Study: | 40 Years to 79 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | Yes |
Sampling Method: | Non-Probability Sample |
Untreated, clinical stage I and II non-small cell lung cancer (NSCLC) patients and matching healthy control subjects will be recruited to participate in this study.
Untreated patients have not yet had either complete surgical removal of their lung cancer, any chemotherapy, or any radiation therapy to treat their lung cancer.
Inclusion Criteria:
Patients with untreated stage I-II NSCLC OR Healthy control subjects: with a > 20 pack year history of cigarette smoking OR Never smokers (defined as less than 100 cigarettes over subject's lifetime)
Exclusion Criteria:
Scottsdale Healthcare |
University of California, Los Angeles |
University of Colorado at Denver and Health Sciences Center |
Department of Veterans Affairs |
University of Kansas |
Principal Investigator: | Glen J Weiss, MD | TGen Clinical Research Services at Scottsdale Healthcare |
Responsible Party: | TGen Clinical Research Services at Scottsdale Healthcare ( Glen J. Weiss, MD ) |
Study ID Numbers: | 2007-094, IASLC |
First Received: | January 22, 2008 |
Last Updated: | July 15, 2008 |
ClinicalTrials.gov Identifier: | NCT00607425 |
Health Authority: | United States: Institutional Review Board |
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