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Sponsored by: |
University of Wisconsin, Madison |
Information provided by: | University of Wisconsin, Madison |
ClinicalTrials.gov Identifier: | NCT00214110 |
This is a single-center, phase 2 randomized clinical trial of tamoxifen on mean percent predicted isometric muscle strength in patients with amyotrophic lateral sclerosis (ALS). The purpose is to determine whether the triphenylethylenetamoxifen, used as adjuvant therapy in the treatment of breast cancer, can delay the loss of isometric muscle strength in ALS patients.
Condition | Intervention | Phase |
Amyotrophic Lateral Sclerosis (ALS) |
Drug: Tamoxifen |
Phase II |
Genetics Home Reference related topics: | amyotrophic lateral sclerosis |
MedlinePlus related topics: | Amyotrophic Lateral Sclerosis |
Drug Information available for: | Tamoxifen Tamoxifen citrate |
Study Type: | Interventional |
Study Design: | Randomized, Single Blind, Active Control, Parallel Assignment |
Official Title: | Phase 2 Randomized Single-Blind Escalating Dose Response Clinical Trial of Tamoxifen Therapy on Mean Percent Predicted Isometric Strength in Amyotrophic Lateral Sclerosis [ALS] |
Estimated Enrollment: | 100 |
Study Start Date: | January 2001 |
Study Completion Date: | January 2005 |
Ages Eligible for Study: | 18 Years to 90 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
United States, Wisconsin | |||||
University of Wisconsin | |||||
Madison, Wisconsin, United States, 53792 |
University of Wisconsin, Madison |
Principal Investigator: | Benjamin R Brooks, MD | University of Wisconsin, Madison |
Responsible Party: | University of Wisconswin ( Benjamin Rix Brooks, MD ) |
Study ID Numbers: | 2000-486 |
First Received: | September 13, 2005 |
Last Updated: | August 14, 2008 |
ClinicalTrials.gov Identifier: | NCT00214110 |
Health Authority: | United States: Institutional Review Board |
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