Effects of Nerve Block on Knee Function After Knee Replacement - Full Text View

Effects of Nerve Block on Knee Function After Knee Replacement

This study is currently recruiting participants.
Verified by Johns Hopkins University, July 2006

Sponsored by:	Johns Hopkins University
Information provided by:	Johns Hopkins University
ClinicalTrials.gov Identifier:	NCT00358241

Purpose

Early physical therapy after knee surgery is very painful on top of pain from surgery. Pain following surgery can limit recovery. One way to treat pain is by giving intravenous (IV) pain medication with morphine. Another method is to use a “nerve block” which involves placing a thin catheter (tube) into the lower back near the nerves that sense pain in the knee and give a local anesthetic to numb the nerves. Sometimes both methods are used together. This research is being done to determine whether nerve blocks with a local anesthetic improve knee recovery in addition to providing pain relief as compared to IV pain medicine alone

Condition	Intervention
Postoperative Pain	Procedure: Nerve block

MedlinePlus related topics:

Knee Replacement

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Randomized, Double-Blind, Placebo Control, Parallel Assignment

Official Title:	Effects of Continuous Lumbar Plexus Nerve Block on Functional Restoration and Outcome After Unilateral Total Knee Arthroplasty

Eligibility

Ages Eligible for Study:	21 Years to 80 Years
Genders Eligible for Study:	Both

Criteria

Inclusion Criteria:

Age 21-80 year old
ASA Physical Status ASA I and II
Mentally competent
Intellectually competent
Body mass index <35
No severe cardiac diseases
No severe pulmonary diseases
Unilateral knee disease
No other lower extremity joint disease
No chronic narcotic therapy or illicit drug use

Exclusion Criteria:

Age <21 or >80 year old
ASA Physical Status >ASA II
Mentally incompetent
Intellectually incompetent or cognitively impaired
Non-English speaking patient
Worker’s compensation patient
Body mass index > 35
Bilateral knee disease
Has other lower extremity joint disease
Severe cardiac diseases
Severe pulmonary diseases
Chronic narcotic therapy or illicit drug use
Pregnancy

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00358241

Contacts


Contact: A. Rollingson	410-550-0942

Locations


United States, Maryland
	Johns Hopkins Bayview Medical Center	Recruiting
	Baltimore, Maryland, United States, 21224
	Contact: A Rollingson 410-550-0942

Sponsors and Collaborators

Johns Hopkins University

Investigators


Principal Investigator:	J Hang, MD, PhD	Johns Hopkins Medicine, Johns Hopkins University

More Information

Study ID Numbers:	04-03-05-05
First Received:	July 27, 2006
Last Updated:	July 27, 2006
ClinicalTrials.gov Identifier:	NCT00358241
Health Authority:	United States: Institutional Review Board

Keywords provided by Johns Hopkins University:

Nerve block, postoperative pain, analgesia

Study placed in the following topic categories:

Signs and Symptoms

Postoperative Complications

Pain

Pain, Postoperative

Additional relevant MeSH terms:

Pathologic Processes

ClinicalTrials.gov processed this record on November 04, 2008