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Sponsors and Collaborators: |
University of Utah Anecare |
Information provided by: | University of Utah |
ClinicalTrials.gov Identifier: | NCT00708526 |
The proposed study will measure the decrease in time to meet discharge criteria from the PACU and a reduction in the incidence of adverse events when hypercapnic hyperpnoea is used during emergence.
Condition | Intervention | Phase |
Hypercapnia |
Device: QED Other: standard of care for phase one anesthesia care |
Phase II |
MedlinePlus related topics: | Anesthesia |
Study Type: | Interventional |
Study Design: | Health Services Research, Randomized, Single Blind (Caregiver), Active Control, Parallel Assignment, Safety Study |
Official Title: | Improved Patient Recovery After Anesthesia With Hypercapnia Hyperpnoea |
Estimated Enrollment: | 45 |
Study Start Date: | March 2008 |
Estimated Study Completion Date: | June 2009 |
Estimated Primary Completion Date: | April 2009 (Final data collection date for primary outcome measure) |
Arms | Assigned Interventions |
2: Experimental
QED is in place for phase 1 anesthesia recovery
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Device: QED
The QED is place in the anesthesia circuit prior to wake up
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1: Active Comparator
monitoring of subject recovering during anesthesia phase 1 and phase 2
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Other: standard of care for phase one anesthesia care
standard of care
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Hypercapnia has been used in conjunction with hyperpnoea to provide a more rapid return of responsiveness after inhaled anesthesia (1-4). In our first clinical study with isoflurane we confirmed that the time from turning off the vaporizer to opening of eyes was shortened by an average of 62% when the minute ventilation was elevated and the EtCO2 was kept at 52 mmHg rather than 28 mmHg during emergence (5). In our second study we found that hypercapnia and hyperpnoea accelerated recovery proportionately for sevoflurane and desflurane (6). The benefits of accelerating subject recovery in the operating room may extend to the entire recovery period if the subject is more alert and easier to care for when they arrive in the post anesthesia care unit (PACU).
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contact: Dwayne Westenskow | 581-2478 | dwayne.westenskow@hsc.utah.edu |
Contact: Julia White | 587-4806 | julia.white@hsc.utah.edu |
United States, Utah | |||||
University of Utah | Recruiting | ||||
Salt Lake City, Utah, United States, 84132 | |||||
Contact: Dwayne Westenskow 801-581-8478 dwayne.westenskow@hsc.utah.edu | |||||
Contact: Julia White 801 587-4806 julia.white@hsc.utah.edu | |||||
Principal Investigator: Dwayne Westenskow |
University of Utah |
Anecare |
Principal Investigator: | Dwayne Westenskow | University of Utah |
Responsible Party: | Anecare ( Dwayne Westenskow ) |
Study ID Numbers: | 26111 |
First Received: | June 30, 2008 |
Last Updated: | June 30, 2008 |
ClinicalTrials.gov Identifier: | NCT00708526 |
Health Authority: | United States: Institutional Review Board |
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