The Department of Energy (DOE) manages a significant portion of the Nation’s R&D enterprise through its program offices.  DOE’s Office of Science (SC) is the single largest supporter of basic research in the physical sciences in the United States, providing more than 40 percent of total funding for physics, chemistry, materials science and other areas of the physical sciences.  SC also manages research at 10 national laboratories and the world’s most diverse portfolio of unique and powerful scientific tools – including particle accelerator centers, neutron sources, high-powered light sources, advanced computational centers, and atmospheric monitoring facilities.  In addition DOE, through the Office of Science, funds more than 7,000 individual research projects at universities, national laboratories, U.S. industry and the non-profit sector.