Treatment for Women With Post-Traumatic Stress Disorder Related to Childhood Abuse - Full Text View

Purpose

This study will compare one- and two-component treatments in women with post-traumatic stress disorder (PTSD).

Condition	Intervention
Stress Disorders, Post-Traumatic	Behavioral: Psychotherapy treatment

MedlinePlus related topics:

Post-Traumatic Stress Disorder Stress

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment, Randomized, Single Blind, Active Control, Parallel Assignment, Efficacy Study

Official Title:	Skills Training, Exposure, and Their Combination in Childhood Abuse PTSD

Further study details as provided by National Institute of Mental Health (NIMH):

Estimated Enrollment:	144
Study Start Date:	April 2002

Detailed Description:

PTSD is a debilitating and often chronic anxiety disorder with serious psychiatric comorbidity. The most common trauma associated with PTSD among women is childhood abuse. PTSD related to childhood abuse may cause problems with emotion regulation and interpersonal functioning. This study will address three domains of PTSD related to childhood abuse: emotion management problems, interpersonal problems, and PTSD symptoms.

Participants in this study will be randomly assigned to 16 sessions of one of three treatments: Skills Training for Affective and Interpersonal Regulation (STAIR), which focuses on helping individuals strengthen and build skills in managing feelings and improving interpersonal relationships; Modified Prolonged Exposure (MPE), which focuses on developing narratives of abuse history and completing an "emotional processing" of the trauma in a safe environment; and a combination of STAIR and MPE. Dropout rates and adverse effects will be measured.

Eligibility

Ages Eligible for Study:	22 Years to 65 Years
Genders Eligible for Study:	Female
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

DSM-IV criteria for Post-Traumatic Stress Disorder related to childhood physical and/or sexual abuse by a care-giver
At least one clear memory of the abuse
Willing to have all assessments tape recorded and sessions video taped
Willing to maintain any concurrent treatments for the duration of the study

Exclusion Criteria:

Bipolar Disorder
Eating Disorder
Borderline Personality Disorder
Active substance abuse or dependence
Living with the abuser
Self mutilation
Pregnancy

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00069381

Locations


United States, New York
	NYU Child Study Center Institute for Trauma and Stress
	New York, New York, United States, 10016

Sponsors and Collaborators

National Institute of Mental Health (NIMH)

More Information

Related Info This link exits the ClinicalTrials.gov site

Study ID Numbers:	R01 MH62347, DSIR 83-ATAS
First Received:	September 24, 2003
Last Updated:	October 15, 2008
ClinicalTrials.gov Identifier:	NCT00069381
Health Authority:	United States: Federal Government

Study placed in the following topic categories:

Anxiety Disorders

Mental Disorders

Stress Disorders, Post-Traumatic

Stress

Stress Disorders, Traumatic

Additional relevant MeSH terms:

Pathologic Processes

Disease

ClinicalTrials.gov processed this record on October 31, 2008

Sponsored by:	National Institute of Mental Health (NIMH)
Information provided by:	National Institute of Mental Health (NIMH)
ClinicalTrials.gov Identifier:	NCT00069381