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Cold Water Immersion Modulates Reinforcing Effects of Nitrous Oxide - 2

This study has been completed.

Sponsors and Collaborators: National Institute on Drug Abuse (NIDA)
University of Chicago
Information provided by: National Institute on Drug Abuse (NIDA)
ClinicalTrials.gov Identifier: NCT00000250
  Purpose

The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. Comparisons between nitrous oxide, opiates, and benzodiazepine antagonists will be made. To evaluate: cold water immersion modulates the reinforcing effects of nitrous oxide in healthy volunteers.


Condition Intervention Phase
Opioid-Related Disorders
Substance-Related Disorders
Drug: Nitrous oxide
Phase II

MedlinePlus related topics:   Drinking Water   

Drug Information available for:   Nitrous oxide   

U.S. FDA Resources

Study Type:   Interventional
Study Design:   Treatment
Official Title:   Cold Water Immersion Modulates Reinforcing Effects of Nitrous Oxide

Further study details as provided by National Institute on Drug Abuse (NIDA):

Primary Outcome Measures:
  • Pain intensity, pain bothersomeness
  • Mood
  • Psychomotor performance
  • Choice of nitrous oxide vs. placebo

Estimated Enrollment:   0
Study Start Date:   December 1993

  Eligibility
Ages Eligible for Study:   21 Years to 32 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Criteria

Please contact site for information.

  Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00000250

Locations
United States, Illinois
University of Chicago, Anesthesia & Critical Care    
      Chicago, Illinois, United States, 60637

Sponsors and Collaborators

Investigators
Principal Investigator:     James Zacny, Ph.D.     University of Chicago    
  More Information


Study ID Numbers:   NIDA-08391-2, R01-08391-2
First Received:   September 20, 1999
Last Updated:   June 23, 2005
ClinicalTrials.gov Identifier:   NCT00000250
Health Authority:   United States: Federal Government

Study placed in the following topic categories:
Mental Disorders
Nitrous Oxide
Substance-Related Disorders
Disorders of Environmental Origin
Opioid-Related Disorders

Additional relevant MeSH terms:
Disease
Physiological Effects of Drugs
Central Nervous System Depressants
Anesthetics
Pharmacologic Actions
Anesthetics, Inhalation
Pathologic Processes
Analgesics, Non-Narcotic
Sensory System Agents
Anesthetics, General
Therapeutic Uses
Analgesics
Peripheral Nervous System Agents
Central Nervous System Agents

ClinicalTrials.gov processed this record on October 29, 2008




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