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Does Lead Burden Alter Neuropsychological Development?

This study has been completed.

Sponsors and Collaborators: National Center for Research Resources (NCRR)
HRSA/Maternal and Child Health Bureau
Information provided by: National Center for Research Resources (NCRR)
ClinicalTrials.gov Identifier: NCT00000104
  Purpose

Inner city children are at an increased risk for lead overburden. This in turn affects cognitive functioning. However, the underlying neuropsychological effects of lead overburden and its age-specific effects have not been well delineated. This study is part of a larger study on the effects of lead overburden on the development of attention and memory. The larger study is using a multi-model approach to study the effects of lead overburden on these effects including the event-related potential (ERP), electrophysiologic measures of attention and memory are studied. Every eight months, for a total of three sessions the subjects will complete ERP measures of attention and memory which require them to watch various computer images while wearing scalp electrodes recording from 11 sites. It is this test that we are going to be doing on CRC. There will be 30 lead overburdened children recruited from the larger study for participation in the ERP studies on CRC. These 30 children will be matched with 30 children without lead overburden. This portion of the study is important in providing an index of physiological functioning to be used along with behaviorally based measures of attention and memory, and for providing information about the different measures.


Condition Intervention
Lead Poisoning
Procedure: ERP measures of attention and memory

MedlinePlus related topics:   Lead Poisoning    Memory    Poisoning   

U.S. FDA Resources

Study Type:   Observational
Study Design:   Longitudinal, Defined Population
  Eligibility
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes

Criteria

Inclusion Criteria:

  • Pregnant mothers of the Phillips neighborhood in Minneapolis, Minnesota. Subject recruitment will take place in local clinics which serve pregnant women and offspring
  Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00000104

Locations
United States, Minnesota
Department of Neurology 420 Delaware St. SE, Box 486 Mayo    
      Minneapolis, Minnesota, United States, 55455

Sponsors and Collaborators
National Center for Research Resources (NCRR)
HRSA/Maternal and Child Health Bureau
  More Information


Study ID Numbers:   NCRR-M01RR00400-0587, M01RR00400
First Received:   November 3, 1999
Last Updated:   June 23, 2005
ClinicalTrials.gov Identifier:   NCT00000104
Health Authority:   United States: Federal Government

Keywords provided by National Center for Research Resources (NCRR):
lead overburden  

Study placed in the following topic categories:
Lead Poisoning
Poisoning
Disorders of Environmental Origin

ClinicalTrials.gov processed this record on October 31, 2008




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