ASAP Study - Hospital-Based Brief Intervention for Alcohol Problems - Full Text View

Purpose

The objective of this project was to test whether screening and brief intervention for unhealthy alcohol use leads to improved alcohol-related outcomes (such as alcohol consumption and linkage to alcohol assistance) and is cost-effective.

Condition	Intervention	Phase
Alcohol Dependence Alcohol Consumption	Behavioral: Brief Intervention (adaptation of motivational interviewing)	Phase III

MedlinePlus related topics:

Alcohol Consumption Alcoholism

Drug Information available for:

Ethanol

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Efficacy Study

Official Title:	Hospital-Based Brief Intervention for Alcohol Problems

Further study details as provided by National Institute on Alcohol Abuse and Alcoholism (NIAAA):

Primary Outcome Measures:

Linkage to alcohol assistance
Change in drinks per day

Secondary Outcome Measures:

Change in the number of times a subject exceeded per occasion limits
Abstinence (dichotomous)
Change in drinks per day
Drinking risky amounts (dichotomous)
Binge drinking (dichotomous)
Hospitalization
Emergency Department visits
Health related quality of life
Readiness to change alcohol use

Estimated Enrollment:	350
Study Start Date:	February 2001
Study Completion Date:	April 2006

Detailed Description:

In this study the effectiveness and cost-effectiveness of brief intervention for unhealthy alcohol use in a diverse group of hospitalized medical patients was tested.

We conducted a randomized trial of medical inpatients with the whole spectrum of alcohol problems from risky use through dependence. Subjects in one group received standard care; subjects in the second group received a brief motivational intervention tailored to the severity of his or her alcohol problem. Primary outcomes are alcohol consumption and linkage to alcohol treatment. Additional outcomes include health-related quality of life, health care utilization, alcohol problems, and readiness to change. Costs, and clinical outcomes measured in quality-adjusted life years, a standard metric that allows comparison to other chronic illnesses, will be compared in a cost-effectiveness analysis.

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

18 years of age or older
Fluent in English or Spanish
Consume risky amounts of alcohol
Provide 2 contacts to assist with follow-up
Have no plans to move from the local area within a year of screening
Score >21 on Mini-Mental State Examination (no serious cognitive impairment)

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00183105

Locations


United States, Massachusetts
	Boston Medical Center
	Boston, Massachusetts, United States, 02118

Sponsors and Collaborators

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

University of Pittsburgh

Boston University

Investigators


Principal Investigator:	Richard Saitz, M.D., M.P.H.	Boston Medical Center

More Information

Publications of Results:

Kraemer KL, Roberts MS, Horton NJ, Palfai T, Samet JH, Freedner N, Tibbetts N, Saitz R. Health utility ratings for a spectrum of alcohol-related health states. Med Care. 2005 Jun;43(6):541-50.

Publications indexed to this study:

Saitz R, Palfai TP, Cheng DM, Horton NJ, Freedner N, Dukes K, Kraemer KL, Roberts MS, Guerriero RT, Samet JH. Brief intervention for medical inpatients with unhealthy alcohol use: a randomized, controlled trial. Ann Intern Med. 2007 Feb 6;146(3):167-76. Summary for patients in: Ann Intern Med. 2007 Feb 6;146(3):I22.

Study ID Numbers:	NIAAASaitz12617-ASAP, NIH AA12617
First Received:	September 9, 2005
Last Updated:	December 6, 2007
ClinicalTrials.gov Identifier:	NCT00183105
Health Authority:	United States: Federal Government

Keywords provided by National Institute on Alcohol Abuse and Alcoholism (NIAAA):

Alcohol

Alcohol abuse

Alcohol dependence

Utilization

Alcohol consumption

Unhealthy alcohol use

Hospitalization

Screening

Brief Intervention

Motivational Interviewing

Randomized trial

Effectiveness

Unhealthy alcohol use (Risky alcohol consumption amounts, problem alcohol use, hazardous alcohol use, alcohol abuse and alcohol dependence)

Alcohol abuse

Study placed in the following topic categories:

Mental Disorders

Alcoholism

Substance-Related Disorders

Drinking Behavior

Disorders of Environmental Origin

Alcohol-Related Disorders

Alcohol Drinking

Ethanol

ClinicalTrials.gov processed this record on October 29, 2008

Sponsors and Collaborators:	National Institute on Alcohol Abuse and Alcoholism (NIAAA) University of Pittsburgh Boston University
Information provided by:	National Institute on Alcohol Abuse and Alcoholism (NIAAA)
ClinicalTrials.gov Identifier:	NCT00183105