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PET/CT to Identify "Vulnerable" Arterial Plaque

This study is currently recruiting participants.
Verified by Rambam Health Care Campus, November 2006

Sponsored by: Rambam Health Care Campus
Information provided by: Rambam Health Care Campus
ClinicalTrials.gov Identifier: NCT00416065
  Purpose

The purpose of this research is to evaluate the presence, location and intensity of FDG uptake in the large arteries using the new technology of fused PET/CT imaging and to compare FDG uptake with the presence of arterial calcifications as seen on the simultaneously acquired CT, in order to determine if FDG was increases incalcified plaque or in a different location in the arterial wall. we will also evaluate the relationship between FDG localization and future cardiovascular events in out patient population


Condition Intervention
Cancer
Device: PET/CT imaging

U.S. FDA Resources

Study Type:   Interventional
Study Design:   Randomized, Open Label, Uncontrolled, Single Group Assignment
Official Title:   PET/CT to Identify "Vulnerable" Arterial Plaque

Further study details as provided by Rambam Health Care Campus:

Primary Outcome Measures:
  • the impact of the imaging modality on patient management

Secondary Outcome Measures:
  • the impact of the imaging modality on patient management

Estimated Enrollment:   800
Study Start Date:   April 2004

  Eligibility
Ages Eligible for Study:   50 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Criteria

Inclusion Criteria:

  • Patients referred for clinical FDG-PET/CT studies
  • Patients 50 yr or older
  • Patients signed informed consent

Exclusion Criteria:

  • Patients unable or unwilling to tolerate the scan until its completion
  Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00416065

Contacts
Contact: Ora Israel, MD     972-4-8543009     o_israel@rambam.health.gov.il    

Locations
Israel
Rambam Medical Center     Recruiting
      Haifa, Israel
      Contact: Ora Israel, MD     972-4-8543009     o_israel@rambam.health.gov.il    

Sponsors and Collaborators
Rambam Health Care Campus

Investigators
Principal Investigator:     Ora Israel, MD     Rambam Health Care Campus    
  More Information


Study ID Numbers:   plaqueCTIL
First Received:   December 26, 2006
Last Updated:   December 26, 2006
ClinicalTrials.gov Identifier:   NCT00416065
Health Authority:   Israel: Israeli Health Ministry Pharmaceutical Administration

ClinicalTrials.gov processed this record on October 22, 2008




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