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Sponsored by: |
University of Pavia |
Information provided by: | University of Pavia |
ClinicalTrials.gov Identifier: | NCT00659451 |
The anthypertensive treatment with Losartan may have benefits beyond blood pressure reduction on myocardial structure and function in hypertensive diabetic patients. We will evaluate the effect of losartan treatment on structural characteristics of myocardium in hypertensive diabetic patients:
Condition | Intervention | Phase |
Essential Hypertension Diabetes Mellitus |
Drug: Losartan Drug: Amlodipine |
Phase III |
MedlinePlus related topics: | Diabetes High Blood Pressure |
ChemIDplus related topics: | Losartan Losartan potassium Amlodipine Amlodipine besylate |
Study Type: | Interventional |
Study Design: | Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Safety/Efficacy Study |
Official Title: | Effects Of Losartan On Myocardial Structure And Function And On Epicardial Fat Deposition In Diabetic Hypertensive Patients With Left Ventricular: Qualitative And Quantitative Alteration |
Estimated Enrollment: | 100 |
Study Start Date: | April 2008 |
Estimated Study Completion Date: | April 2009 |
Primary Completion Date: | April 2008 (Final data collection date for primary outcome measure) |
Arms | Assigned Interventions |
2: Experimental
Losartan
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Drug: Losartan
tablets; 50, 100 mg; od; 12 months
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1: Active Comparator
Amlodipine
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Drug: Amlodipine
tablets; 5, 10 mg; od; 12 months
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Ages Eligible for Study: | 40 Years to 80 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contact: Roberto Fogari | +39 0382 526217 |
Italy | |||||
University of Pavia | Recruiting | ||||
Pavia, Italy | |||||
Contact: Paola Preti, MD +39 0382 526217 | |||||
Sub-Investigator: Paola Preti |
University of Pavia |
Responsible Party: | University of Pavia ( Paola Preti/MD ) |
Study ID Numbers: | UNIPV002DIM2008 |
First Received: | April 14, 2008 |
Last Updated: | April 14, 2008 |
ClinicalTrials.gov Identifier: | NCT00659451 |
Health Authority: | Italy: National Monitoring Centre for Clinical Trials - Ministry of Health |
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