Hospital In-Patient Insulin Study - Full Text View

Purpose

Hyperglycaemia has been shown to increase morbidity and mortality in patients with critical illness, myocardial infarction and stroke. This study aims to look at patients with hyperglycaemia and reduce their blood sugar levels using differing combinations of subcutaneous and intravenous insulin.

Condition	Intervention	Phase
Diabetes Mellitus, Type 2	Drug: Detemir	Phase IV

MedlinePlus related topics:

Diabetes

ChemIDplus related topics:

Insulin

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Safety/Efficacy Study

Official Title:	A Randomised Study Comparing Continuous Intravenous Insulin Infusion With Subcutaneous Insulin Analogues in Hospitalised Patients With Type II Diabetes and Hyperglycaemia

Further study details as provided by The Royal Bournemouth Hospital:

Primary Outcome Measures:

Glucose control

Secondary Outcome Measures:

Length of stay

Enrollment:	41
Study Start Date:	July 2005
Study Completion Date:	June 2006

Detailed Description:

This is a randomised trial involving patients with type II diabetes who are brought into the hospital with a problem other than a diabetic emergency. Patients will be included, who have a blood sugar > than 17mmols. They will be randomised to one of two groups and either given intravenous or subcutaneous insulin. Outcome measures are length of stay, glucose control and comparison of the two regimens. Cost implications will also be analysed.

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Type II diabetes
Blood glucose > 17mmols

Exclusion Criteria:

Type I diabetes
Hyperosmolar non-ketotic coma (HONK)
Diabetic ketoacidosis (DKA)
Myocardial infarction (MI)
Vomiting

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00135070

Locations


United Kingdom, Dorset
	The Royal Bournemouth Hospital
	Bournemouth, Dorset, United Kingdom, BH7 7DW

Sponsors and Collaborators

The Royal Bournemouth Hospital

Investigators


Principal Investigator:	David Kerr, Doctor	The Royal Bournemouth Hospital

More Information

Study ID Numbers:	H.P.I.1
First Received:	August 23, 2005
Last Updated:	April 27, 2007
ClinicalTrials.gov Identifier:	NCT00135070
Health Authority:	United Kingdom: Research Ethics Committee

Keywords provided by The Royal Bournemouth Hospital:

Diabetes Mellitus

Study placed in the following topic categories:

Metabolic Diseases

Hyperglycemia

Diabetes Mellitus, Type 2

Diabetes Mellitus

Endocrine System Diseases

Endocrinopathy

Metabolic disorder

Glucose Metabolism Disorders

Insulin

ClinicalTrials.gov processed this record on October 17, 2008

Sponsored by:	The Royal Bournemouth Hospital
Information provided by:	The Royal Bournemouth Hospital
ClinicalTrials.gov Identifier:	NCT00135070