ClinicalTrials.gov
 Home    Search    Study Topics    Glossary  
 

  Full Text View  
  Tabular View  
  Contacts and Locations  
  No Study Results Posted  
  Related Studies  
Does the Relaxation Response Inhibit Acute Stress?

This study is currently recruiting participants.
Verified by Beth Israel Deaconess Medical Center, October 2007

Sponsors and Collaborators: Beth Israel Deaconess Medical Center
Centers for Disease Control and Prevention
Information provided by: Beth Israel Deaconess Medical Center
ClinicalTrials.gov Identifier: NCT00179595
  Purpose

The purposes of this study are:

  1. To examine molecular and biochemical changes, associated with the relaxation response (RR) that can counteract the effects of stress in healthy adults.
  2. To compare genomic, molecular and biochemical parameters between healthy adults with a long term meditative practice and those with no experience in meditation.

Since stress is a factor in the development of many health conditions, a further understanding of the mechanisms of the RR should be developed. The project is designed to determine how the RR can improve the quality of life that has been adversely affected by stress.


Condition Intervention Phase
Healthy
Behavioral: relaxation response- meditation
Phase II

MedlinePlus related topics:   Stress   

ChemIDplus related topics:   Nitric oxide   

U.S. FDA Resources

Study Type:   Interventional
Study Design:   Treatment, Randomized, Double-Blind, Active Control, Parallel Assignment, Efficacy Study
Official Title:   Does the Relaxation Response Inhibit Acute Stress?

Further study details as provided by Beth Israel Deaconess Medical Center:

Primary Outcome Measures:
  • To examine molecular and biochemical changes, associated with the relaxation response (RR) that can counteract the effects of stress in healthy adults.

Secondary Outcome Measures:
  • To compare genomic, molecular and biochemical parameters between healthy adults with a long term meditative practice and those with no experience in meditation.

Estimated Enrollment:   140
Study Start Date:   May 2002

Detailed Description:

The purposes of this study are:

  1. To examine molecular and biochemical changes, associated with the relaxation response (RR) that can counteract the effects of stress in healthy adults.
  2. To compare genomic, molecular and biochemical parameters between healthy adults with a long term meditative practice and those with no experience in meditation.

Since stress is a factor in the development of many health conditions, a further understanding of the mechanisms of the RR should be developed. The project is designed to determine how the RR can improve the quality of life that has been adversely affected by stress.

  Eligibility
Ages Eligible for Study:   18 Years to 49 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes

Criteria

Inclusion Criteria:

  • healthy individual
  • age:18-49 years
  • able to read and understand English
  • able to attend al study visits
  • access to a telephone (to schedule visits)

Exclusion Criteria:

  • current smoking
  • asthma
  • current use of any prescription or psychoactive medications or supplements
  • either:

    1. no prior experience with RR eliciting techniques
    2. at least 3 years of regular RR elicitation (at least 20 min/day)
  • BMI >30
  • exhaled nitric oxide levels >60 ppb
  • abnormal lab values (Hct <32,creatinine >1.3, glucose >200
  • pregnancy
  Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00179595

Contacts
Contact: Jeffery A Dusek, PhD     617-991-0102     jdusek@bidmc.harvard.edu    

Locations
United States, Massachusetts
Beth-Israel Deaconess Medical Center     Recruiting
      Boston, Massachusetts, United States, 02215
      Contact: Jeffery A Dusek, PhD     617-991-0201 ext 212     jdusek@bidmc.harvard.edu    
      Principal Investigator: Herbert Benson, MD            

Sponsors and Collaborators
Beth Israel Deaconess Medical Center
Centers for Disease Control and Prevention

Investigators
Principal Investigator:     Herbert Benson, MD     Beth Israel Deaconess Medical Center    
  More Information


Study ID Numbers:   2001-P-001747, H75-CCH-123424, H75-CCH-119124
First Received:   September 13, 2005
Last Updated:   October 30, 2007
ClinicalTrials.gov Identifier:   NCT00179595
Health Authority:   United States: Institutional Review Board;   United States: Centers for Disease Control and Prevention;   United States: Food and Drug Administration;   United States: Department of Health and Human Services;   United States: National Institutes of Health;   United States: Office for Human Research Protections

Keywords provided by Beth Israel Deaconess Medical Center:
nitric oxide, volumetric oxygen consumption  

Study placed in the following topic categories:
Nitric Oxide
Stress
Healthy

ClinicalTrials.gov processed this record on October 17, 2008




Links to all studies - primarily for crawlers