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Matthew L. Becker , Ph.D.



 

 

photograph of Matthew Becker

Check my publications

Research Chemist

Biomaterials
  
    Phone:
(301) 975-6842
    Fax:
(301) 975-4977
    Email:
    Mail:
8543
 

Research Interests

My current research efforts are centered on the development of functional materials, which incorporate bio-functional species in a controlled manner, including stoichiometry and regioselectivity. These constructs are used to identify, characterize and quantify the critical interactions, material compositions and physico-chemical properties which interact with cell membranes and influence normal biological processes.

Professional Background

2005 - Present - Staff Scientist,

2003 - 2005 - NRC Postdoctoral Fellow

2003 Ph.D. Washington University, Organic Chemistry
Advisor: Professsor Karen L. Wooley

1998 B.S. Northwest Missouri State University, Chemistry


NRC Research Opportunities

The Material-Directed Cell Function project involves three areas of research: biomarker probe development, phage display, and functional surfaces. If interested in postdoctoral or fellowship opportunities, please contact me. Current opportunities: Matthew Becker


Honors and Awards

2003 - 2005 - National Research Council Postdoctoral Fellowship
2001 - 2003 - NIH Chemistry-Biology Interface Training Fellowship
2000 - Dean's Award for Teaching Excellence - Washington University
1999 - Department of Chemistry, Teaching Award - Washington University
1998 - Outstanding Graduate in Chemistry


Select Publications

Biomaterials
MD Roy, SJ Stanley, EJ Amis, ML Becker* 'High Specificity Hydroxyapatite Binding Motif Identified via Phage Display' Advanced Materials, 2008, 20(10), 1830-1836.

MD Roy, A Herzing, SH Lacerda, ML Becker* 'Emission-Tunable, Microwave Synthesis of Highly Luminescent Water Soluble Quantum Dots' Chemical Communications, 2008, 2106-2108.

AW Morgan, KE Roskov, S Lin-Gibson, DL Kaplan, ML Becker*, CG Simon* 'Morphology and Beta-Sheet structure in Silk Blend Films Influences Cell Differentiation.' Biomaterials, 2008, 29(16), 2556-2563.

Y Yang, D Bolikal, ML Becker, J Kohn, D Zieger, CG Simon, 'Combinatorial Polymer Scaffold Libraries for Screening Cell-Biomaterial Interactions in 3D' Advanced Materials, 2008, 20(11) 2037-2043.

Y Yang, SD Dorsey, ML Becker, S Lin-Gibson, GE Schumacher, GM Flaim, J Kohn, CG Simon, 'X-ray Imaging Optimization of 3D Tissue Engineering Scaffolds via Combinatorial Fabrication Methods' Biomaterials, 2008, 29(12), 1901-1911.

ND Gallant, KA Lavery, EJ Amis, ML Becker*, "Universal Substrate for 'Click' Biofunctionalization" Advanced Materials, 2007, 19(7), 965-969.

CG Simon, JS Stephens, SM Dorsey, ML Becker "Fabrication of Combinatorial Polymer Scaffold Libraries" Review Scientific Instruments, 2007, 78, 072207.

LO Bailey, ML Becker, JS Stephens, ND Gallant, CM Mahoney, NR Washburn, A Rege, J Kohn, EJ Amis, 'Cellular Responses to Phase-separated Blends of Tyrosine-derived Polycarbonates.' Journal of Biomedical Materials Research, 2006, 76A, 491-502.

B Hammouda, F Horkay, ML Becker, 'Clustering and Solvation in Poly(acrylic acid) Polyelectrolyte Solutions.' Macromolecules, 2005, 38, 2019-2021.

Carbon Nanotubes
JA Fagan, ML Becker, J Chun, EK Hobbie 'Length Fractionation of Carbon Nanotubes using Centrifugation' Advanced Materials, 2008, 20(9) 1609-1614.

ML Becker, JA Fagan, ND Gallant, BJ Bauer, V Bajpai, EK Hobbie, SH Lacerda, KB Migler, JP Jakupciak "Length Dependent Uptake of DNA-wrapped Single Wall Carbon Nanotubes" Advanced Materials, 2007, 19(7), 939-945.

JA Fagan, JR Simpson, BJ Bauer, SH Lacerda, ML Becker, KB Migler, AR Hight-Walker, EK Hobbie, 'Optical Measurements on Size Fractionated Single Wall Carbon Nanotubes' J. Am. Chem. Soc., 2007, 129(34), 10607-10612.

BJ Bauer, ML Becker, V Bajpai, JA Fagan, EK Hobbie, K Migler, CM Guttman, WR Blair, 'SWNT Dispersion as Measured by Size Exclusion Chromatography' J Phys Chem C, 2007, 111(48), 17914-17918.

BJ Bauer, EK Hobbie, ML Becker, 'Small Angle Neutron Scattering from Labeled Single Wall Carbon Nanotubes' Macromolecules, 2006, 39, 2637-2642.

Washington University
X Sun, R Rossin, JL Turner, ML Becker, MJ Joralemon, KL Wooley, MJ Welch, 'An Assessment of Shell Crosslinked Nanoparticle Size, Core Composition, and Surface PEGylation Effects on In vivo Biodistribution.' Biomacromolecules, 2005, 6, 2541-2554.

JL Turner, ML Becker, X Li, J-SA Taylor, KL Wooley, 'PNA Directed Solution and Surface Assembly of Shell Crosslinked (SCK) Nanoparticle Conjugates.' Soft Matter. 2005, 1(1) 69-78.

ML Becker, J Liu, KL Wooley, 'Peptide Functionalized Micellar Assemblies Prepared via Block Copolymers Synthesized by Living Free Radical Polymerization on Solid Support.' Biomacromolecules, 2005, 6, 220-228.

MJ Joralemon, KS Murthy, EE Remsen, ML Becker, KL Wooley, Synthesis, Characterization, and Bioactivity of Mannosylated Shell Crosslinked Nanoparticles. Biomacromolecules, 2004, 5, 903-913.

ML Becker, EE Remsen, D Pan, KL Wooley, 'Peptide Derivatized Shell Cross-linked Nanoparticles. 1) Synthesis and Characterization.' Bioconjugate Chemistry, 2004, 15(4), 699-709.

ML Becker, LO Bailey, KL Wooley, 'Peptide Derivatized Shell Cross-linked Nanoparticles. 2) Biocompatibility Evaluation.' Bioconjugate Chemistry, 2004, 15(4), 710-717.

ML Becker, J Liu, KL Wooley, 'Peptide-polymer Bio-conjugates: Hybrid block copolymers generated via living radical polymerizations from resin supported peptides.' Chem. Comm. 2003, 2, 180-181.

ML Becker, EE Remsen, KL Wooley, 'Diblock Copolymers, Micelles, and Shell Crosslinked Nanoparticles Containing Poly(4-Fluorostyrene): Tools for detailed analysis of nanostructured materials.' J. Polym. Sci. Part A: Polym. Chem. 2001, 39(23), 4152-4166.


 
 
 
 
NIST Materials Science & Engineering Laboratory - Polymers Division