Research Interests

Professional Background

• B.S. in Chemistry from Faculty of Sciences and Mathematics, Department of Chemistry, University of Zagreb, Zagreb, Croatia in 1975.
• Ph.D. in Chemistry from Faculty of Sciences and Mathematics, University of Zagreb, Zagreb, Croatia in 1979.
Dissertation Title: Kinetics of Precipitation of Lead(II) Carbonates
• Research Assistant, Research Associate and Project Leader at Rudjer Boskovic Institute, Zagreb, 1975 - 1992.
• Associate Professor (Docent) in Department of General and Inorganic Chemistry, Faculty of Sciences and Mathematics, University of Zagreb, Zagreb, 1990 - 1995.
• Guest Scientist at the ADAF PRC, NIST, Gaithersburg, 1991 - 1995.
• Research Associate II at the ADAF PRC, NIST, Gaithersburg, 1995 to Present.

Honors and Awards

Selected Publications

• Calcium Phosphate Chemistry
• Markovic M, Fowler BO, Brown WE (1993). Octacalcium phosphate carboxylates. 1. Preparation and identification. Chem Mater 5:1401-1405.
• Markovic M, Fowler BO, Brown WE (1993). Octacalcium phosphate carboxylates. 2. Characterization and structural considerations. Chem Mater 5:1406-1416.
• Fowler BO, Markovic M, Brown WE (1993). Octacalcium phosphate. 3. Infrared and Raman vibrational spectra. Chem Mater 5:1417-1423.
• Markovic M, Fowler BO, Brown WE (1994). Octacalcium phosphate carboxylates. IV. Kinetics of formation and solubility of octacalcium phosphate succinate. J Crystal Growth 135:533-538.
• Markovic M, Fowler BO, Brown WE (1994). Octacalcium phosphate carboxylates. 5. Incorporation of excess succinate and ammonium ions in the octacalcium phosphate succinate structure. In: Hydroxyapatite and Related Materials, P.W. Brown and B.R. Constanz, eds. Boca Raton: CRC Press, pp. 139-144.
• Markovic M, Fowler BO, Tung MS, Lagergren ES (1995). Composition and solubility product of a synthetic calcium hydroxyapatite. Chemical and thermal determination of Ca/P ratio and statistical analysis of chemical and solubility data. In: Mineral and Scale Formation, Proc. of Am. Chem. Soc. Symp., Z. Amjad, ed. New York, London: Plenum, pp. 181-188.
• Markovic M (2001). Octacalcium Phosphate Carboxylates, In: Monographs in Oral Science, Vol 18: Octacalcium Phosphates, Chow, L.C. and Eanes, E.D., eds. Basel: Karger, pp. 77-93.
• Markovic M, Fowler BO, Tung MS (2003). Preparation and comprehensive characterization of calcium hydroxyapatite. J. Res. NIST, in preparation.
• Biomaterials and Biomineralization
• Chow LC, Markovic M, Takagi S, Cherng M (1997). Effects of cement liquid on the physical properties of the cement. Innov. Techn. Biol. Med. (Numero Special GRIBOL 97), 18: 11-14.
• Markovic M, Takagi, S, Chow LC (1998). Properties of calcium phosphate carbonate cements, In: Transactions of Twenty-Fourth Annual Meeting of the Society for Biomaterials, Volume XXI, Minneapolis: Society for Biomaterials, pp. 38.
• Chow LC, Markovic M, Takagi S (1998). Calcium phosphate cements. In: Cements Research Progress, Chapter 7, Struble LJ, ed. American Ceramic Society, pp. 215-238.
• Chow LC, Markovic, M, Takagi S (1999). Formation of hydroxyapatite in cement systems: Effects of phosphate. Phosphorus, Sulfur and Silicon and Related Elements 144-146:129-132.
• Markovic M, Takagi S, Chow LC (2000). Formation of macropores in calcium phosphate cements through the use of mannitol crystals. In: Bioceramics 13, Proc. of the 13th Int. Symposium on Ceramics in Medicine (Bologna, Italy), Giannini S and Moroni A, eds. Singapore: World Scientific, pp. 773-776.
• Takagi S, Chow LC, Markovic M, Friedman CD, Costantino PD (2000). Morphological and phase characterizations of retrieved calcium phosphate cement implants. J Biomed Mat Res (Applied Biomaterials) 58:36-41.
• Markovic M, Takagi S, Chow LC (2000). Reduced hardening time of calcium phosphate cements, In: Transactions of the Sixth World Biomaterials Congress, Volume I, Minneapolis: Society for Biomaterials, pp. 340.
• Chow LC, Markovic M, Takagi S (2003). A dual constant-composition titration system as an in vitro resorption model for comparing dissolution rates of calcium phosphate biomaterials. J Biomed Mater Res (Applied Biomaterials), in press.
• Dental Caries Prevention
• Chow LC, Markovic M (1998). Physicochemical properties of fluorapatite. In: Calcium phosphates in biological, industrial, and environmental systems, Amjad Z, ed. Norwell, MA: Kluwer Academic Publishers, pp.67-81.
• Chow LC, Takagi S, Ftukhtbeyn S, Sieck B, Parry EE, Liao S, Schumacher G, Markovic M (2002). Remineralization effect of a low concentration fluoride rinse in an intraoral model. Caries Res. 36:136-141.