Mailing Address

Professional Background

Research Opportunities

NIST-NRC Postdoctoral Fellowship: 2-year fellowship at NIST, US citizens only, $60,000 salary plus benefits, relocation expenses included, application deadlines are Feb. 1 and Aug. 1, requires 3000-word research proposal, contact me if interested in writing proposal on biomaterials research project.

NIST/NIH-NRC Postdoctoral Fellowship: 2-year fellowship, split time at NIST and NIH, open to foreign nationals, $55,000 salary plus benefits, relocation expenses included, application deadline is Aug. 1, requires 3000-word research proposal, contact me if interested in writing proposal on biomaterials research project.

Summer Undergraduate Research Fellowship (SURF): 12-week summer research fellowship at NIST, $4000 stipend, free travel and housing, application deadline is Feb. 15, contact me if interested in doing summer research on biomaterials.

Publications

Gallant ND, Simon Jr CG, Kipper MJ (2008) Discerning statistical significance in non-normally distributed data sets: cell spreading on biomaterial surfaces. Biotechniques, in preparation.

Simon Jr CG, Yang Y, Thomas V, Morgan AW (2008) Cell interactions with biomaterials gradients and arrays. Combinatorial Chemistry and High-Throughput Screening, in preparation. (review)

Yang Y, Becker ML, Bolikal D, Kohn J, Simon Jr CG (2008) Combinatorial polymer scaffold libraries for screening cell-biomaterial interactions in 3D. Advanced Materials, in press.

Chen RI*, Gallant ND, Smith JR, Kipper MJ, Simon Jr CG. (2008) Cell adhesion and spreading on poly(D,L-lactic acid) films pre-aged in cell medium. Journal of Materials Science: Materials in Medicine 19, 1759-1766. (*undergraduate)

Morgan AW, Roskov KE, Lin-Gibson S, Kaplan DL, Becker ML, Simon Jr CG (2008) Characterization and optimization of RGD-containing silk blends to support osteoblastic differentiation. Biomaterials 29, 2556-2563.

Yang Y, Dorsey SM*, Becker ML, Lin-Gibson S, Schumacher GE, Flaim GM, Kohn J, Simon Jr CG (2008) X-ray imaging optimization of 3D tissue engineering scaffolds via combinatorial fabrication methods. Biomaterials 29, 1901-1911. (*undergraduate)

Simon Jr CG, Stephens JS, Dorsey SM*, Becker ML (2007) Fabrication of combinatorial polymer scaffold libraries. Review of Scientific Instruments 78, 0722071-0722077. (*undergraduate)

Kennedy SB, Washburn NR, Simon Jr CG, Amis EJ. (2006) High-throughput Investigation of Osteoblast Response to Surface Energy: Influence on Proliferation and Cell Spreading. Biomaterials 27, 3817-3824.

Simon Jr CG, Eidelman N, Kennedy SB, Sehgal A, Khatri CA, Washburn NR (2005) High-throughput screening of cell proliferation on poly(L-lactic acid)/poly(D,L-lactic acid) blends. Biomaterials 26, 6906-6915.

Zhang K, Simon Jr CG, Lin-Gibson S, Antonucci JM, Washburn NR (2005) In Situ Formation of Blends by Photopolymerization of Poly(ethylene glycol) Dimethacrylate (PEGDMA) and Polylactide (PLA). Biomacromolecules 6, 1615-1622.

Simon Jr CG, Deng Y, Eidelman N, Washburn NR (2004) High-throughput method for determining modulus of polymer blends. Macromolecular Rapid Communications 25, 2003-2007. (Cover Image)

Simon Jr CG (2004) Imaging cells on polymer spherulites. Journal of Microscopy 216, 153-155. (Cover Image)

Eidelman N, Simon Jr CG (2004) Characterization of combinatorial polymer blend composition gradients by FTIR microspectroscopy. Journal of Research of the National Institute of Standards and Technology 109, 219-231.

Bailey LO, Washburn NR, Simon Jr CG, Wang FW, Chan E (2004) The quantification of inflammatory cellular responses using real time polymerase chain reaction. Journal of Biomedical Materials Research 69A, 305-313.

Washburn NR, Yamada KM, Simon Jr CG, Kennedy SB, Amis EJ (2004) High-throughput investigation of osteoblast response to crystalline polymers: influence of nanometer-scale roughness on proliferation. Biomaterials 25, 1215-1224.

Washburn NR, Simon CG, Tona A, Elgendy HM, Karim A, Amis EJ (2002) Co-extrusion of biocompatible polymers for scaffolds with controlled morphology. Journal of Biomedical Materials Research 59, 690-696. (Cover Image)

CERAMIC BIOMATERIALS

Xu HHK, Weir MD, Simon Jr CG (2008) Injectable and strong nano-apatite scaffolds for cell/growth factor delivery and bone regeneration. Dental Materials, in press. (review)

Xu HHK, Weir MD, Simon Jr CG (2008) In situ setting nano-apatite scaffolds: load-bearing properties and delivery of cells and growth factors. Academy of Dental Materials Transactions 21, 14-29.

Xu HHK, Carey LE, Simon Jr CG (2007) Premixed macroporous calcium phosphate cement sccaffold. Journal of Materials Science: Materials in Medicine 18, 1345-1353.

Xu HHK, Carey LE, Simon Jr CG, Takagi S, Chow LC (2007) Premixed calcium phosphate cements: synthesis, physical properties and cell toxicity. Dental Materials 23, 433-441.

Weir MD, Xu HHK, Simon Jr CG (2006) Strong calcium phosphate cement-chitosan-mesh construct containing cell-encapsulating hydrogel beads for bone tissue engineering. Journal of Biomedical Materials Research 77A, 487-496. (Cover Image)

Simon Jr CG, Antonucci JM, Skrtic D (2005) In vitro cytotoxicity of amorphous calcium phosphate composites. Journal of Bioactive and Compatible Polymers 20, 279-295.

Carey LE, Xu HHK, Simon Jr CG, Takagi S, Chow LC (2005) Premixed rapid-setting calcium phosphate composites for bone repair. Biomaterials 26, 5002-5014.

Zhang K, Washburn NR, Simon Jr CG (2005) Three-dimensionally ordered macroporous sol-gel bioactive glass (3DOM-BG) particles and their in vitro biocompatibility. Biomaterials 26, 4532-4539.

Xu HHK, Simon Jr CG (2005) Fast setting calcium phosphate-chitosan scaffold: mechanical properties and biocompatibility. Biomaterials 26, 1337-1348.

Non-peer reviewed: Xu HHK, Simon Jr CG, Takagi S, Chow LC, Eichmiller FC (2005) Strong, macroporous and in-situ hardening hydroxyapatite scaffold for bone tissue engineering. Biomaterials Forum 27, p. 14, 18-19. (Cover Image)

Xu HHK, Smith DT, Simon Jr CG (2004) Strong and bioactive composites containing nano-silica-fused whiskers for bone repair. Biomaterials 25, 4615-4626.

Xu HHK, Simon Jr CG (2004) Self-hardening calcium phosphate cement-mesh composite: reinforcement, macropores and cell response. Journal of Biomedical Materials Research 69A, 267-278. (Cover Image)

Xu HHK, Simon Jr CG (2004) Self-hardening calcium phosphate composite scaffold for bone tissue engineering. Journal of Orthopaedic Research 22, 535-543.

Simon Jr CG, Guthrie WF, Wang FW (2004) Cell seeding into calcium phosphate cement. Journal of Biomedical Materials Research 68A, 628-639.

Simon Jr CG, Khatri CA, Wight SA, Wang FW (2002) Preliminary report on the biocompatibility of a moldable, resorbable, composite bone graft consisting of calcium phosphate cement and poly(lactide-co-glycolide) microspheres. Journal of Orthopaedic Research 20, 473-482.

BIOCHEMISTRY

Dahir GA, Cui Q, Anderson P, Simon Jr CG, Joyner C, Triffitt JT, Balian G (2000) Pluripotential Mesenchymal Cells Repopulate Bone Marrow and Retain Osteogenic Properties. Clinical Orthopaedics and Related Research 379S, S134-S145.

Simon Jr CG, Holloway PW, Gear ARL (1999) Exchange of C16-ceramide between phospholipid vesicles. Biochemistry 38, 14676-14682.

Simon Jr CG, Gear ARL (1999) Sphingolipid metabolism during human platelet activation. Thrombosis Research 94, 13-23.

Polanowska-Grabowska R, Simon Jr CG, Gear ARL (1999) Platelet adhesion to collagen type I, collagen type IV, von Willebrand factor, fibronectin, laminin, and fibrinogen: rapid kinetics under shear. Thrombosis and Haemostasis 81, 118-123.

Simon Jr CG, Chatterjee S, Gear ARL (1998) Sphingomyelinase activity in human platelets. Thrombosis Research 90, 155-161.

Simon Jr CG, Gear ARL (1998) Membrane-destabilizing properties of C2-ceramide may be responsible for its ability to inhibit platelet aggregation. Biochemistry 37, 2059-2069.

Gear ARL, Simon CG, Polanowska-Grabowska R (1997) Platelet adhesion to collagen activates a phosphoprotein complex of heat-shock proteins and protein phosphatase 1. Journal of Neural Transmission 104, 1037-1047.

Polanowska-Grabowska R, Simon Jr CG, Falchetto R, Shabanowitz J, Hunt DF, Gear ARL (1997) Platelet adhesion to collagen under flow causes dissociation of a phosphoprotein complex of heat-shock proteins and protein phosphatase 1. Blood 90, 1516-1526.

Honors, Awards & Other Activities

Chair, ASTM Working Group F044200.06 Reference Scaffolds for Tissue Engineering, 2007-present.

Program Chair, Proteins & Cells at Interfaces Special Interest Group, Society for Biomaterials, 2007-2008. (elected)

Symposia Organizer, "Cell Function on Biomaterial Gradients & Arrays", Society for Biomaterials, Chicago, 2007. (175 attendees)

Cover Image, Journal of Biomedical Materials Research, Volume 77A, Issue 3, 2006.

Cover Image, Biomaterials Forum, Volume 27, Issue 1, 2005.

Cover Image, Macromolecular Rapid Communications, Volume 25, Number 24, 2004.

Cover Image, Journal of Microscopy, Volume 216, Number 2, 2004.

Cover Image, Journal of Biomedical Materials Research, Volume 69A, Number 2, 2004.

Olympus BioScapes Digital Imaging Competition, Honorable Mention for "Cells on Spherulites", 2004.

Cell image featured on the cover of the Polymers Division 2003 Annual Report.

Cover Image, Journal of Biomedical Materials Research, Volume 60, Number 1, 2002.

Bone tissue engineering research highlighted as a significant accomplishment in the Polymers Division Annual Report, NIST, 2001.

Post-doctoral Fellowship, National Institute of Standards and Technology, 1999-2003.

Post-doctoral Fellowship, Dr. Adrian Gear, Biochemistry Department, University of Virginia, 1999.

University of Virginia, Biochemistry Department, Doctoral Student Stipend, 1992-1998.

Brookhaven National Lab, Summer Student Research Stipend, 1991.

Bucknell University, Burpee Biology Student Summer Research Stipend, 1990.

Balfour Award, Sigma Chi Fraternity; Chosen as the outstanding senior of 1992.

Big Brothers/Big Sisters of America Service Award, Susquehanna Valley Chapter, 1992.