The conceptual framework underlying the TEACH Research Program is based on a specific theoretical approach designed to influence adolescent career choice, in this case towards a career in clinical research. The factors responsible for influencing career choice that form the foundation for our investigation are: 1) the importance of role models in career choice; 2) acquisition of knowledge in order to align ambitions; and 3) the participation of students in activities that actively challenge and engage them. These three factors are addressed by the following three components of the TEACH Research Intervention: 1) participation in a research team consisting of a multi-tiered structure of mentors; 2) classroom instruction of clinical research knowledge and career strategies; and 3) a hands-on clinical research experience through an intership on the Hospitalist Project.

The evaluation of TEACH Research (Teaching Early Achievers for Careers in Health) aims to rigorously evaluate a precollege enrichment program in clinical research targeting high school students particularly underrepresented minorities, in order to increase the entry and success of these students into careers in clinical research. Through these measures, the TEACH Research Program will educate high achieving minority students and in turn hopefully encourage and promote these students to think about a career in clinical research.