Back to: Research : Division of Intramural Research
Most Recent Publications
- Bell M, Wang H, Chen H, McLenithan JC, Gong DW, Yang RZ, Yu D, Fried SK, Quon MJ, Londos C, Sztalryd C. Consequences of lipid droplet coat protein downregulation in liver cells: abnormal lipid droplet metabolism and induction of insulin resistance. Diabetes. 2008 Aug;57(8):2037–45.
- Tesauro M, Schinzari F, Rovella V, Melina D, Mores N, Barini A, Mettimano M, Lauro D, Iantorno M, Quon MJ, Cardillo C. Tumor necrosis factor-alpha antagonism improves vasodilation during hyperinsulinemia in metabolic syndrome. Diabetes Care. 2008 Jul;31(7):1439–41.
- Koh KK, Park SM, Quon MJ. Leptin and cardiovascular disease: response to therapeutic interventions. Circulation. 2008 Jun 24;117(25):3238–49.
- Koh KK, Quon MJ, Han SH, Lee Y, Ahn JY, Kim SJ, Koh Y, Shin EK. Simvastatin improves flow-mediated dilation but reduces adiponectin levels and insulin sensitivity in hypercholesterolemic patients. Diabetes Care. 2008 Apr;31(4):776–82.
- Arnold, JT, Le, H, McFann, KK, Blackman, MR. 2005 Comparative effects of DHEA vs. testosterone, dihydrotestosterone, and estradiol on proliferation and gene expression in human LNCaP prostate cancer cells. Am J Physiol Endocrinol Metab. Mar 2008; 288(3):E573–84.
- Hoffman KE, Derdak J, Bernstein D, Reynolds JC, Avila NA, Gerber L, Steinberg SM, Chrousos G, Mackall CL, Mansky PJ. Metabolic syndrome traits in long-term survivors of pediatric sarcoma. Pediatr Blood Cancer. 2008 Feb;50(2):341–6.
- Koh KK, Quon MJ, Rosenson RS, Chung WJ, Han SH. Vascular and metabolic effects of treatment of combined hyperlipidemia: focus on statins and fibrates. Int J Cardiol. 2008 Feb 29;124(2):149–59.
- Lee S, Muniyappa R, Yan X, Chen H, Yue LQ, Hong EG, Kim JK, Quon MJ. Comparison between surrogate indexes of insulin sensitivity and resistance and hyperinsulinemic euglycemic clamp estimates in mice. Am J Physiol Endocrinol Metab. 2008 Feb;294(2):E261–70.
- Koh KK, Quon MJ, Han SH, Lee Y, Ahn JY, Kim SJ, Koh Y, Shin EK. Simvastatin Improves Flow-Mediated Dilation, but Reduces Adiponectin Levels and Insulin Sensitivity In Hypercholesterolemic Patients. Diabetes Care. 2008 Jan 9.
- Koh KK, Quon MJ, Waclawiw MA. Are statins effective for simultaneously treating dyslipidemias and hypertension? Atherosclerosis. 2008 Jan;196(1):1–8.
- Lee S, Lynn EG, Kim JA, Quon MJ. Protein Kinase C-{zeta} phosphorylates Insulin Receptor Substrate-1, -3, and -4, but not -2: isoform specific determinants of specificity in insulin signaling. Endocrinology. 2008 Jan 17.
- Muniyappa R, Lee S, Chen H, Quon MJ. Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage. Am J Physiol Endocrinol Metab. 2008 Jan;294(1):E15–26.
- Zhao WQ, De Felice FG, Fernandez S, Chen H, Lambert MP, Quon MJ, Krafft GA, Klein WL. Amyloid beta oligomers induce impairment of neuronal insulin receptors. FASEB J. 2008 Jan;22(1):246–60.
- Arnold, JT, Blackman, MR. 2005. Does Dehydroepiandrosterone exert direct effects on androgen and estrogen receptors, and does it promote or prevent prostate cancer? Endocrinology Vol. 146, No. 11 4565–4567. Invited Editorial.
- Dalrymple, S. Antony, L, Xu, Y, Uzgare, AR Arnold, JT, Savaugeot, J, Sokoll, LJ, De Marzo, AM and Isaacs JT. 2005 Role of Notch-1 and E-Cadherin in the Differential Response to Calcium in Culturing Normal versus Malignant Prostate, Cancer Res., 65: 9269–9279.
- Le, H, Arnold, JT, McFann, KK, Blackman, MR, 2006 Differential modulation of IGF-I, IGF Binding Protein 2 and IGFBP-3 Expression by Dihydrotestosterone and Testosterone in Primary Cultures of Human Prostatic Stromal Cells AmJ Physiol Endocrinol Metab 290(5):E952–60.
- Steele, VE,, Arnold, JT, Le, H, Izmirilian, G and Blackman, MR, 2006, Comparative Effects of DHEA and DHT on Gene Expression in Human LNCaP Prostate Cancer Cells, Anticancer Research, Vol 26:5A, pp. 3205–3216.
- Collins QF, Liu HY, Pi J, Liu Z, Quon MJ, Cao W. Epigallocatechin-3-gallate (EGCG), a green tea polyphenol, suppresses hepatic gluconeogenesis through 5'-AMP-activated protein kinase. J Biol Chem. 2007 Oct 12;282(41):30143–9.
- Khoromi S, Blackman MR, Kingman A, Patsalides A, Matheny LA, Adams S, Pilla AA, Max MB. Low intensity permanent magnets in the treatment of chronic lumbar radicular pain. J Pain Symptom Manage. 2007 Oct;34(4):434–45.
- Koh KK, Quon MJ, Han SH, Ahn JY, Lee Y, Shin EK. Combined therapy with ramipril and simvastatin has beneficial additive effects on tissue factor activity and prothrombin fragment 1+2 in patients with type 2 diabetes. Atherosclerosis. 2007 Sep;194(1):230–7.
- Mammarella S, Creati B, Staniscia T, Verginelli F, Manzoli L, Di Valerio A, Aceto G, Romano F, Cama G, Capani F, Consoli A, Vitacolonna E, Esposito-Del Puente A, Battista P, Della Loggia F, Mariani-Costantini R, Quon MJ, Cama A. Obesity modifies the effects of the Asp905Tyr variant of PPP1R3A on risk of type 2 diabetes and insulin sensitivity. Diabetes Obes Metab. 2007 Sep;9(5):759–61.
- Muniyappa R, Sorkin JD, Veldhuis JD, Harman SM, Münzer T, Bhasin S, Blackman MR. Long-term testosterone supplementation augments overnight growth hormone secretion in healthy older men. Am J Physiol Endocrinol Metab. 2007 Sep;293(3):E769–75.
- Xu L, Lao LX, Ge A, Yu S, Li J, Mansky PJ. Chinese herbal medicine for cancer pain. Integr Cancer Ther. 2007 Sep;6(3):208–34.
- Arnold, JT, Liu, X Allen, JD, Le, H, McFann, KK, Blackman, MR. Androgen Receptor or Estrogen Receptor-beta Blockade alters DHEA-DHT- and E2-induced Proliferation and PSA production in human prostate cancer cells. Prostate. 2007, Aug 1;67(11):1152–62.
- Muniyappa R, Montagnani M, Koh KK, Quon MJ. Cardiovascular actions of insulin. Endocr Rev. 2007 Aug;28(5):463–91.
- Manoli I, Alesci S, Blackman MR, Su YA, Rennert OM, Chrousos GP. Mitochondria as key components of the stress response. Trends Endocrinol Metab. 2007 Jul;18(5):190–8.
- Muniyappa R, Quon MJ. Insulin action and insulin resistance in vascular endothelium. Curr Opin Clin Nutr Metab Care. 2007 Jul;10(4):523–30.
- Koh KK, Quon MJ, Lee SJ, Han SH, Ahn JY, Kim JA, Chung WJ, Lee Y, Shin EK. Efonidipine simultaneously improves blood pressure, endothelial function, and metabolic parameters in nondiabetic patients with hypertension. Diabetes Care. 2007 Jun;30(6):1605–7.
- Koh KK, Quon MJ, Lee Y, Han SH, Ahn JY, Chung WJ, Kim JA, Shin EK. Additive beneficial cardiovascular and metabolic effects of combination therapy with ramipril and candesartan in hypertensive patients. Eur Heart J. 2007 Jun;28(12):1440–7.
- Kim JA, Formoso G, Li Y, Potenza MA, Marasciulo FL, Montagnani M, Quon MJ. Epigallocatechin gallate, a green tea polyphenol, mediates NO-dependent vasodilation using signaling pathways in vascular endothelium requiring reactive oxygen species and Fyn. J Biol Chem. 2007 May 4;282(18):13736–45.
- Muniyappa R, Quon MJ. Is further research needed on glucosamine? J Fam Pract. 2007 May;56(5):343.
- Potenza MA, Marasciulo FL, Tarquinio M, Tiravanti E, Colantuono G, Federici A, Kim JA, Quon MJ, Montagnani M. EGCG, a green tea polyphenol, improves endothelial function and insulin sensitivity, reduces blood pressure, and protects against myocardial I/R injury in SHR. Am J Physiol Endocrinol Metab. 2007 May;292(5):E1378–87.
- Bai X, Wu J, Zhang Q, Alesci S, Manoli I, Blackman MR, Chrousos GP, Goldstein AL, Rennert OM, Su YA. Third-generation human mitochondria-focused cDNA microarray and its bioinformatic tools for analysis of gene expression. Biotechniques. 2007 Mar;42(3):365–75.
- Iantorno M, Chen H, Kim JA, Tesauro M, Lauro D, Cardillo C, Quon MJ. Ghrelin has novel vascular actions that mimic PI 3-kinase-dependent actions of insulin to stimulate production of NO from endothelial cells. Am J Physiol Endocrinol Metab. 2007 Mar;292(3):E756–64.
- Stickle DF, Seligman ML, Landmark JD, Quon MJ. Predicted effects of hemoglobin A1c assay precision on a patient population distribution of serial hemoglobin A1c difference values. Clin Chim Acta. 2007 Mar;378(1–2):201–5.
- Tesauro M, Rizza S, Iantorno M, Campia U, Cardillo C, Lauro D, Leo R, Turriziani M, Cocciolillo GC, Fusco A, Panza JA, Scuteri A, Federici M, Lauro R, Quon MJ. Vascular, metabolic, and inflammatory abnormalities in normoglycemic offspring of patients with type 2 diabetes mellitus. Metabolism. 2007 Mar;56(3):413–9.
- Han SH, Quon MJ, Kim JA, Koh KK. Adiponectin and cardiovascular disease: response to therapeutic interventions. J Am Coll Cardiol. 2007 Feb 6;49(5):531–8.
- Han SH, Quon MJ, Koh KK. Reciprocal relationships between abnormal metabolic parameters and endothelial dysfunction. Curr Opin Lipidol. 2007 Feb;18(1):58–65.
- Mansky P, Arai A, Stratton P, Bernstein D, Long L, Reynolds J, Chen D, Steinberg SM, Lavende N, Hoffman K, Nathan PC, Parks R, Augustine E, Chaudhry U, Derdak J, Wiener L, Gerber L, Mackall C. Treatment late effects in long-term survivors of pediatric sarcoma. Pediatr Blood Cancer. 2007 Feb;48(2):192–9.
- Rao, JS, Ertley, RN, Lee, HJ, Demar Jr, JC, Arnold, JT , Rapoport, SI and Bazinet, RP, n-3 Polyunsaturated Fatty Acid Deprivation in Rats Decreases Frontal Cortex BDNF Via A p38 MAPK Dependent Mechanism, Mol Psychiatry. 2007 Jan;12(1):36–46