A Randomized, Double-Blind, Trial Comparing Epinephrine Versus Phenylephrine as a Vasoconstrictor in Regional Anesthesia for Upper Extremity Surgery - Full Text View

A Randomized, Double-Blind, Trial Comparing Epinephrine Versus Phenylephrine as a Vasoconstrictor in Regional Anesthesia for Upper Extremity Surgery

This study has been completed.

Sponsored by:	New York Methodist Hospital
Information provided by:	New York Methodist Hospital
ClinicalTrials.gov Identifier:	NCT00225043

Purpose

The study involves research, the purpose of which is to compare three different drug mixtures (Epinephrine, Phenylephrine 25 µg, or Phenylephrine 50 µg). Specifically, how long each medicine lasts will be studied.

Condition	Intervention
Healthy	Drug: Epinephrine/phenylephrine

ChemIDplus related topics:

Phenylephrine Guaifenesin Naphazoline Naphazoline hydrochloride Oxymetazoline Oxymetazoline hydrochloride Phenylephrine hydrochloride Phenylpropanolamine Phenylpropanolamine hydrochloride Epinephrine Epinephrine bitartrate

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Other, Randomized, Double-Blind, Active Control, Parallel Assignment

Further study details as provided by New York Methodist Hospital:

Enrollment:	60
Study Start Date:	June 2005
Study Completion Date:	August 2007
Primary Completion Date:	August 2007 (Final data collection date for primary outcome measure)

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

Shoulder surgery with regional anesthesia

Exclusion Criteria:

Shoulder surgery with general anesthesia unhealthy

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00225043

Locations


United States, New York
	New York Methodist Hospital
	Brooklyn, New York, United States, 11215

Sponsors and Collaborators

New York Methodist Hospital

Investigators


Principal Investigator:	Joel Yarmush, MD, MPA	New York Methodist Hospital

More Information

Responsible Party:	New York Methodist Hospital ( Joel Yarmush )
Study ID Numbers:	299
First Received:	September 21, 2005
Last Updated:	May 30, 2008
ClinicalTrials.gov Identifier:	NCT00225043
Health Authority:	United States: Institutional Review Board

Study placed in the following topic categories:

Pseudoephedrine

Naphazoline

Oxymetazoline

Guaifenesin

Phenylephrine

Salicylsalicylic acid

Sodium Salicylate

Ephedrine

Phenylpropanolamine

Healthy

Epinephrine

Additional relevant MeSH terms:

Respiratory System Agents

Neurotransmitter Agents

Adrenergic Agents

Molecular Mechanisms of Pharmacological Action

Cardiotonic Agents

Physiological Effects of Drugs

Adrenergic Agonists

Nasal Decongestants

Therapeutic Uses

Vasoconstrictor Agents

Appetite Depressants

Adrenergic alpha-Agonists

Adrenergic beta-Agonists

Sympathomimetics

Anti-Asthmatic Agents

Cardiovascular Agents

Protective Agents

Pharmacologic Actions

Anti-Obesity Agents

Mydriatics

Autonomic Agents

Expectorants

Peripheral Nervous System Agents

Bronchodilator Agents

Central Nervous System Agents

ClinicalTrials.gov processed this record on October 10, 2008