Randomized Controlled Trial of Doxycycline to Prevent Acquisition of Mycoplasma Pneumoniae in an Outbreak Setting - Full Text View

Randomized Controlled Trial of Doxycycline to Prevent Acquisition of Mycoplasma Pneumoniae in an Outbreak Setting

This study has been completed.

Sponsored by:	Centers for Disease Control and Prevention
Information provided by:	Centers for Disease Control and Prevention
ClinicalTrials.gov Identifier:	NCT00207584

Purpose

This study was designed to determine whether taking daily doxycycline during an outbreak of Mycoplasma pneumoniae could prevent a person from getting infected and interrupt ongoing disease transmission during an outbreak. Doxycycline is a treatment for Mycoplasma pneumoniae, but it is not certain that the drug could prevent disease if used prophylactically.

Condition	Intervention
Mycoplasma Pneumoniae	Drug: Doxycycline treatment

MedlinePlus related topics:

Pneumonia

ChemIDplus related topics:

Doxycycline Doxycycline calcium Doxycycline hyclate

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Randomized, Double-Blind, Placebo Control, Parallel Assignment

Official Title:	A Double-Blind, Randomized Placebo-Controlled Trial of Doxycycline for Chemoprophylaxis in the Setting of an Outbreak of Mycoplasma Pneumoniae

Further study details as provided by Centers for Disease Control and Prevention:

Study Start Date:	January 1994
Estimated Study Completion Date:	April 1994

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

- Working at hospital facility where outbreak of Mycoplasma pneumoniae occured

Exclusion Criteria:

- Pregnant, on antiseizure medications, allergic to macrolide antibiotics

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00207584

Sponsors and Collaborators

Centers for Disease Control and Prevention

Investigators


Principal Investigator:	Julia A Schillinger, MD	Centers for Disease Control and Prevention

More Information

Study ID Numbers:	CDC-NCHSTP-9997
First Received:	September 13, 2005
Last Updated:	September 13, 2005
ClinicalTrials.gov Identifier:	NCT00207584
Health Authority:	United States: Federal Government

Study placed in the following topic categories:

Bacterial Infections

Pneumonia, Mycoplasma

Mycoplasmal pneumonia

Pleurisy

Pleural Diseases

Mycoplasma Infections

Pleuropneumonia

Gram-Negative Bacterial Infections

Respiratory Tract Diseases

Respiratory Tract Infections

Lung Diseases

Pneumonia, Bacterial

Doxycycline

Pneumonia

Additional relevant MeSH terms:

Mycoplasmatales Infections

Antimalarials

Anti-Infective Agents

Anti-Bacterial Agents

Antiparasitic Agents

Antiprotozoal Agents

Therapeutic Uses

Pharmacologic Actions

ClinicalTrials.gov processed this record on October 10, 2008