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Allograft Fibrosis Following Pediatric Cardiac Transplantation

This study is ongoing, but not recruiting participants.

Sponsored by: Children's Healthcare of Atlanta
Information provided by: Children's Healthcare of Atlanta
ClinicalTrials.gov Identifier: NCT00328185
  Purpose

Transplantation is the preferred method of treating many forms of end-stage organ failure. While short-term results have improved, long-term outcomes remain inadequate. Myocardial fibrosis could potentially have an adverse effect on long-term cardiac function. We wish to study the degree of fibrosis to see if we can predict survival following pediatric heart transplantation.


Condition
Children Who Underwent Heart Transplantation Prior to Age 18
Received Care at Children's Healthcare of Atlanta

MedlinePlus related topics:   Heart Transplantation   

U.S. FDA Resources

Study Type:   Observational
Study Design:   Natural History, Longitudinal, Defined Population, Retrospective Study
Official Title:   Allograft Fibrosis: Its Regulation and Significance Following Pediatric Cardiac Transplantation

Further study details as provided by Children's Healthcare of Atlanta:

Estimated Enrollment:   60
Study Start Date:   January 2006

Show detailed description  Show Detailed Description

  Eligibility
Ages Eligible for Study:   up to 18 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Criteria

Inclusion Criteria:

  • Children who underwent heart transplantation prior to age 18
  • Followed up at Children's Healthcare of Atlanta

Exclusion Criteria:

  • Children without a transplanted heart
  • Follow-up not at children's Healthcare of Atlanta
  Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00328185

Locations
United States, Georgia
Children's Healthcare of Atlanta    
      Atlanta, Georgia, United States, 30329

Sponsors and Collaborators
Children's Healthcare of Atlanta

Investigators
Principal Investigator:     Brian E Kogon, MD     Emory University    
  More Information


Study ID Numbers:   05-217
First Received:   May 18, 2006
Last Updated:   May 18, 2006
ClinicalTrials.gov Identifier:   NCT00328185
Health Authority:   United States: Food and Drug Administration

Keywords provided by Children's Healthcare of Atlanta:
pediatric  
heart disease  
orthotopic heart transplantation  
allograft fibrosis  

Study placed in the following topic categories:
Heart Diseases
Fibrosis

Additional relevant MeSH terms:
Pathologic Processes

ClinicalTrials.gov processed this record on October 07, 2008




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