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Sponsored by: |
Università degli Studi dell'Insubria |
Information provided by: | Università degli Studi dell'Insubria |
ClinicalTrials.gov Identifier: | NCT00517322 |
Aim of the study is to compare in hypertensive patients the effect of one year therapy with ACE-inhibitor (RAMIPRIL) or angiotensin II receptor blocker (IRBESARTAN) on left atrial remodelling and diastolic function.
Condition | Intervention | Phase |
Left Atrial Volume Hypertensive Heart Disease Antihypertensive Drugs Diastolic Function Renin Angiotensin System |
Drug: ramipril Drug: irbesartan |
Phase IV |
MedlinePlus related topics: | Heart Diseases High Blood Pressure |
ChemIDplus related topics: | Ramipril Irbesartan |
Study Type: | Interventional |
Study Design: | Treatment, Randomized, Double Blind (Subject, Investigator), Active Control, Parallel Assignment, Efficacy Study |
Official Title: | Left Atrial Remodelling in Hypertension: Effects of Ramipril or Irbesartan |
Estimated Enrollment: | 80 |
Study Start Date: | August 2007 |
Estimated Study Completion Date: | August 2010 |
Arms | Assigned Interventions |
1: Experimental
treatment with ramipril
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Drug: ramipril
ramipril 2.5- 5 mg once daily
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2: Experimental
treatment with irbesartan
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Drug: irbesartan
irbesartan 150-300 mg once daily
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Ages Eligible for Study: | 40 Years to 65 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:·
Exclusion Criteria:
Italy | |||||
University of Insubria-Department of Clinical Medicine | Recruiting | ||||
varese, Italy, 21100 | |||||
Contact: anna maria grandi, MD +39+332 278594 amgrandi@libero.it | |||||
Contact: anna maria grandi, MD +39 + 332 278594 amgrandi@libero.it | |||||
Sub-Investigator: andrea maria maresca, MD | |||||
Sub-Investigator: andrea bertolini, MD | |||||
Sub-Investigator: monica gianni, MD | |||||
Sub-Investigator: eleonora nicolini, MD |
Università degli Studi dell'Insubria |
Principal Investigator: | anna maria grandi, MD | university of insubria |
Study ID Numbers: | 1112 |
First Received: | August 15, 2007 |
Last Updated: | August 15, 2007 |
ClinicalTrials.gov Identifier: | NCT00517322 |
Health Authority: | Italy: Ethics Committee |
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