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| Sponsors and Collaborators: |
Norwegian University of Science and Technology The Royal Norwegian Ministry of Health |
| Information provided by: | Norwegian University of Science and Technology |
| ClinicalTrials.gov Identifier: | NCT00516776 |
Purpose
The study includes individuals with ulcerative colitis, Crohn's disease and healthy controls. The purpose of this study is to examine the innate immune system (IIS) by exposing peripheral blood monocytes to various ligands relevant for stimulation of the IIS and study the immune response. Colonic mucosal samples are examined to find gene expression patterns which may distinguish the two forms of disease from each other and from healthy controls.
The hypothesis is that the innate immune system has responses unique for the disease states, and that the diseases may be differentiated by examination of gene expression patterns in mucosal biopsies.
| Condition |
|
Ulcerative Colitis Crohn's Disease Healthy Controls |
| Genetics Home Reference related topics: | Crohn disease |
| MedlinePlus related topics: | Crohn's Disease Ulcerative Colitis |
| Study Type: | Observational |
| Study Design: | Case Control, Cross-Sectional |
| Official Title: | The Innate Immune System and Inflammatory Bowel Disease |
Eligibility
| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
| Sampling Method: | Probability Sample |
Patients from endoscopy unit and outpatients clinic with ulcerative colitis, Crohn's disease and healthy controls
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations| Contact: Arne K Sandvik, MD PhD | +47 73598808 | arne.sandvik@ntnu.no |
| Contact: Helge L Waldum, MD PhD | +47 73868541 | helge.waldum@ntnu.no |
| Norway | |||||
| Dept of Cancer Research and Molecular Medicine, NTNU | Recruiting | ||||
| Trondheim, Norway, NO-7489 | |||||
| Norwegian University of Science and Technology |
| The Royal Norwegian Ministry of Health |
| Principal Investigator: | Arne K Sandvik, MD PhD | Norwegian University of Science and Technology |
More Information
| Responsible Party: | Norwegian University of Science and Technology ( Professor Arne K. Sandvik ) |
| Study ID Numbers: | 5.2007.910 |
| First Received: | August 14, 2007 |
| Last Updated: | May 20, 2008 |
| ClinicalTrials.gov Identifier: | NCT00516776 |
| Health Authority: | Norway: Norwegian Social Science Data Services |
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