Intraocular Pressure (IOP)Assessed by Dynamic Contour Tonometer (DCT) and Glutamic Acid-Alanine-Tyrosine Terpolymer (GAT) - Full Text View

Intraocular Pressure (IOP)Assessed by Dynamic Contour Tonometer (DCT) and Glutamic Acid-Alanine-Tyrosine Terpolymer (GAT)

This study is currently recruiting participants.
Verified by St. Franziskus Hospital, May 2008

Sponsored by:	St. Franziskus Hospital
Information provided by:	St. Franziskus Hospital
ClinicalTrials.gov Identifier:	NCT00552019

Purpose

Purpose of this study is to evaluate assessment of the intraocular pressure with the dynamic contour tonometry and the Goldmann applanation tonometry in patients with active anterior uveitis.

Condition

Uveitis
Intraocular Pressure

ChemIDplus related topics:

Tyrosine Glutamic acid Alanine

U.S. FDA Resources

Study Type:	Observational
Study Design:	Cohort, Prospective

Official Title:	Inflammatory Changes of Corneal Thickness and Influence on Assessment of Intraocular Pressure

Further study details as provided by St. Franziskus Hospital:

Primary Outcome Measures:

IOP by GAT and DCT [ Time Frame: active and inactive uveitis status ]

Biospecimen Retention: None Retained

Biospecimen Description:

Estimated Enrollment:	30
Study Start Date:	October 2007
Estimated Study Completion Date:	December 2008

Detailed Description:

Keratoprecipitates are often found in anterior uveitis. Also elevation of the IOP can be seen in these patients. Goldmann applanation tonometry is the standard technique to assess the IOP but depends on the corneal thickness. Therefore IOP is measured by Goldmann and dynamic contour tonometry and corneal thickness is quantified by Orbscan at active uveitis and after the keratoprecipitates have disappeared.

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Probability Sample

Study Population

tertiary referral center

Criteria

Inclusion Criteria:

active anterior or panuveitis with keratoprecipitates

Exclusion Criteria:

corneal endothelial dystrophy

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00552019

Contacts


Contact: Carsten Heinz, MD	49 251 933080	carsten.heinz@uveitis-zentrum.de

Locations


Germany
	Department of Ophthalmology at St.-Franziskus Hospital	Recruiting
	Münster, Germany, 48145
	Principal Investigator: Carsten Heinz, MD

Sponsors and Collaborators

St. Franziskus Hospital

Investigators


Study Director:	Arnd Heiligenhaus, MD	Department of Ophthalmology at St.-Franziskus Hospital

More Information

Related Info This link exits the ClinicalTrials.gov site

Study ID Numbers:	2007-405-f-S
First Received:	October 31, 2007
Last Updated:	May 23, 2008
ClinicalTrials.gov Identifier:	NCT00552019
Health Authority:	Germany: Federal Ministry of Education and Research

Study placed in the following topic categories:

Uveitis

Eye Diseases

Additional relevant MeSH terms:

Uveal Diseases

ClinicalTrials.gov processed this record on October 07, 2008