Effects of Fetal, Infant, and Early Childhood Exposures on Adult Cancer Risk in Women - Full Text View

Purpose

RATIONALE: Gathering information about pregnancy, infancy, and early childhood exposures may help doctors identify cancer risk factors, and may help the study of cancer.

PURPOSE: This natural history study is looking at the effects of fetal, infant, and early childhood exposures on adult cancer risk in women.

Condition	Intervention
Breast Cancer Unspecified Adult Solid Tumor, Protocol Specific	Procedure: evaluation of cancer risk factors Procedure: questionnaire administration

Genetics Home Reference related topics:

breast cancer

MedlinePlus related topics:

Breast Cancer Cancer

U.S. FDA Resources

Study Type:	Observational

Official Title:	Fetal, Infant and Early Childhood Antecedents of Cancer in Women: Maternal Cohort Study of the Nurses' Health Studies

Further study details as provided by National Cancer Institute (NCI):

Primary Outcome Measures:

Diagnosis of incident cancers and other chronic diseases
Mortality

Estimated Enrollment:	128700
Study Start Date:	October 2000

Detailed Description:

OBJECTIVES:

Determine if fetal, infant, and early childhood exposures are associated with adult cancer risk in women.

OUTLINE: Mothers of nurses complete questionnaires to collect maternal data, such as pregnancy weight gain, diet during pregnancy, maternal pre-eclampsia, gestational diabetes, gestational age at birth, birth weight, and infant feeding practices. Maternal data is linked to other data collected from critical time periods in the nurses's life cycle, such as menarche, first pregnancy, or adult dietary intake.

Eligibility

Ages Eligible for Study:	18 Years to 89 Years
Genders Eligible for Study:	Female
Accepts Healthy Volunteers:	Yes

Criteria

DISEASE CHARACTERISTICS:

Mother of a nurse who is a participant in the Nurses' Health Studies I and II
- Nurse free of cancer in the year 2000

PATIENT CHARACTERISTICS:

Not specified

PRIOR CONCURRENT THERAPY:

Not specified

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00559039

Locations


United States, Maryland
	Warren Grant Magnuson Clinical Center - NCI Clinical Trials Referral Office	Recruiting
	Bethesda, Maryland, United States, 20892-1182
	Contact: Clinical Trials Office - Warren Grant Magnusen Clinical Center 888-NCI-1937

Sponsors and Collaborators

National Cancer Institute (NCI)

Investigators


Principal Investigator:	Michele R. Forman, PhD	M.D. Anderson Cancer Center

More Information

Clinical trial summary from the National Cancer Institute's PDQ® database This link exits the ClinicalTrials.gov site

Study ID Numbers:	CDR0000565931, NCI-01-C-N015
First Received:	November 15, 2007
Last Updated:	July 23, 2008
ClinicalTrials.gov Identifier:	NCT00559039
Health Authority:	Unspecified

Keywords provided by National Cancer Institute (NCI):

breast cancer

unspecified adult solid tumor, protocol specific

Study placed in the following topic categories:

Skin Diseases

Breast Neoplasms

Breast Diseases

Additional relevant MeSH terms:

Neoplasms

Neoplasms by Site

ClinicalTrials.gov processed this record on October 07, 2008

Sponsored by:	National Cancer Institute (NCI)
Information provided by:	National Cancer Institute (NCI)
ClinicalTrials.gov Identifier:	NCT00559039