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| Sponsored by: |
University of Leipzig |
| Information provided by: | University of Leipzig |
| ClinicalTrials.gov Identifier: | NCT00497887 |
Purpose
Atherosclerotic cardiovascular disease is the major cause of morbidity and mortality in Western societies. It is a complex genetic disorder with many genes involved and significant gene-environment interactions. The aim of the study is to identify novel genetic- and biological-markers of atherosclerosis. Atherosclerosis is assessed in the coronay arteries using coronary angiography as well as in the carotid artery (intima-media-thickness) and periperal vessels (ankle brachial index). Association analysis of genetic and metabolic markers with atherosclerotic burden will be performed to identify novel factors of disposition to atherosclerotic vascular disease.
| Condition |
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Atherosclerosis Coronary Arteriosclerosis Carotid Artery Diseases Genetic Predisposition to Disease Biological Markers |
| MedlinePlus related topics: | Carotid Artery Disease |
| Study Type: | Observational |
| Study Design: | Natural History, Cross-Sectional, Defined Population, Prospective Study |
Eligibility
| Ages Eligible for Study: | 18 Years to 85 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations| Contact: Joachim Thiery, MD PhD | +49-341-9722201 | thiery@medizin.uni-leipzig.de |
| Contact: Gerhard Schuler, MD PhD | +49-341-8650 | schug@medizin.uni-leipzig.de |
| Germany | |||||
| University of Leipzig, Heart Center, Department of Cardiology | Recruiting | ||||
| Leipzig, Germany, 04289 | |||||
| Contact: Gerhard Schuler, MD PhD +49-341-8650 | |||||
| Contact: Stephan Gielen, MD PhD +49-341-8650 | |||||
| Principal Investigator: Gerhard Schuler, MD PhD | |||||
| Sub-Investigator: Stephan Gielen, MD PhD | |||||
| Sub-Investigator: Frank Beutner, MD | |||||
| University of Leipzig, Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics | Recruiting | ||||
| Leipzig, Germany, 04103 | |||||
| Contact: Joachim Thiery, MD PhD +49-341-9722201 thiery@medizin.uni-leipzig.de | |||||
| Contact: Daniel Teupser, MD PhD +49-341-9722204 teupser@medizin.uni-leipzig.de | |||||
| Principal Investigator: Joachim Thiery, MD PhD | |||||
| Sub-Investigator: Daniel Teupser, MD PhD | |||||
| Sub-Investigator: Frank Beutner, MD | |||||
| Sub-Investigator: Alexander Leichtle, MD PhD | |||||
| Sub-Investigator: Ralph Burkhardt, MD PhD | |||||
| University of Leipzig |
| Principal Investigator: | Joachim Thiery, MD PhD | University of Leipzig |
More Information
University Hospital Leipzig, Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics
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University of Leipzig, Heart Center
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| Study ID Numbers: | 276-2005 |
| First Received: | July 6, 2007 |
| Last Updated: | July 6, 2007 |
| ClinicalTrials.gov Identifier: | NCT00497887 |
| Health Authority: | Germany: Ethics Commission |
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