A Randomized Controlled Trial on the Effect of Exercise on Physical, Cognitive and Affective Function in Dementia Subjects - Full Text View

A Randomized Controlled Trial on the Effect of Exercise on Physical, Cognitive and Affective Function in Dementia Subjects

This study is currently recruiting participants.
Verified by Hospital Authority, Hong Kong, June 2008

Sponsored by:	Hospital Authority, Hong Kong
Information provided by:	Hospital Authority, Hong Kong
ClinicalTrials.gov Identifier:	NCT00497822

Purpose

Studies have shown conflicting results of the effect of exercise on dementia patients.

The aim of this study is to examine the role of physical activity on the risk of cognitive impairment and dementia in older persons.

To promote the benefits of aerobic exercise on dementia patients and encourage exercise prescription in the management of dementia subjects.

Condition	Intervention
Dementia	Procedure: Aerobic exercise training

MedlinePlus related topics:

Dementia Exercise and Physical Fitness

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Other, Randomized, Single Blind, Active Control, Parallel Assignment, Efficacy Study

Official Title:	To Study the Effect of Exercise Training in Term of Aerobic Exercise for 3 Months, on the Physical, Cognitive and Affective Function in Dementia Subjects

Further study details as provided by Hospital Authority, Hong Kong:

Primary Outcome Measures:

Physical function measurement using SF-12 [ Time Frame: every 3 months for 1 year ]
Affective function measurement by Cornell depression score [ Time Frame: every 3 months for 1 year ]
Cognitive function by MMSE and ADAS-cog [ Time Frame: every 3 months for 1 year ]

Secondary Outcome Measures:

6 minutes walk, functional reach, Berg balance scale [ Time Frame: every 3 months for 1 year ]
Carer stress scale [ Time Frame: every 3 months for 1 year ]
No. of fall/restricted activity days/time spend in exercise or walking [ Time Frame: every 3 months for 1 year ]

Estimated Enrollment:	64
Study Start Date:	January 2006
Estimated Study Completion Date:	October 2007

Eligibility

Ages Eligible for Study:	60 Years and older
Genders Eligible for Study:	Both

Criteria

Inclusion Criteria:

MMSE<26
Age >60
Community dwelling and ambulatory
Have a caregiver that is willing to participate and escort patient to hospital for training and assessment

Exclusion Criteria:

MMSE<10
live in old age home
poor mobility, unable to attend exercise training
no carer to bring patient to attend hospital training

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00497822

Contacts


Contact: Doris KY Miu, Dr	(852) 3517 5326	donnamiu@hotmail.com

Locations


China
	Kwong Wah Hospital	Recruiting
	Hong Kong, China
	Sub-Investigator: Ying Fai Mak, Dr

Sponsors and Collaborators

Hospital Authority, Hong Kong

Investigators


Principal Investigator:	Doris KY Miu, Dr	Department of Medicine and Geriatrics, Kwong Wah Hospital

More Information

HAREC Clinical Trial Registry This link exits the ClinicalTrials.gov site

Study ID Numbers:	KW/EX05-090, HARECCTR0500054
First Received:	July 6, 2007
Last Updated:	June 17, 2008
ClinicalTrials.gov Identifier:	NCT00497822
Health Authority:	Hong Kong: Ethics Committee

Keywords provided by Hospital Authority, Hong Kong:

Dementia

Study placed in the following topic categories:

Delirium, Dementia, Amnestic, Cognitive Disorders

Mental Disorders

Central Nervous System Diseases

Brain Diseases

Dementia

Cognition Disorders

Delirium

Additional relevant MeSH terms:

Nervous System Diseases

ClinicalTrials.gov processed this record on October 06, 2008