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Sponsors and Collaborators: |
UNC Lineberger Comprehensive Cancer Center National Cancer Institute (NCI) |
Information provided by: | National Cancer Institute (NCI) |
ClinicalTrials.gov Identifier: | NCT00499759 |
RATIONALE: An individualized exercise program may be effective in lessening fatigue and depression and improving quality of life in patients undergoing chemotherapy for leukemia.
PURPOSE: This clinical trial is studying how well individualized exercise programs work in patients receiving chemotherapy for newly diagnosed acute or relapsed myeloid leukemia or lymphoblastic leukemia.
Condition | Intervention |
Depression Fatigue Leukemia Musculoskeletal Complications Psychosocial Effects/Treatment |
Procedure: chemotherapy Procedure: exercise intervention Procedure: fatigue assessment and management Procedure: laboratory biomarker analysis Procedure: management of therapy complications Procedure: musculoskeletal complications management Procedure: psychosocial assessment and care Procedure: quality-of-life assessment |
MedlinePlus related topics: | Cancer Depression Exercise and Physical Fitness Leukemia, Adult Acute Leukemia, Adult Chronic |
Study Type: | Interventional |
Study Design: | Other |
Official Title: | In-Hospital Individualized Prescriptive Exercise Intervention for Acute Leukemia Patients Undergoing Chemotherapy |
Estimated Enrollment: | 10 |
Study Start Date: | May 2007 |
OBJECTIVES:
Primary
Secondary
OUTLINE: This is a pilot study.
Patients participate in an individualized prescriptive exercise intervention 3 to 4 times per week for 6 weeks (4 weeks in hospital, 2 weeks at home). Exercise begins concurrently with the first course (induction therapy) of chemotherapy. Each exercise session consist of 3-5 minutes of light stretching (stretching component), 5-10 minutes of cycling on the recumbent bicycle (cardiorespiratory component), 5-15 minutes of resistance training including hand dumbbells, exercise tubing, rubber bands, and fit balls (resistance training component), and 5-10 minutes of abdominal exercises (core muscles component).
Quality of life, fatigue, and depression are assessed at baseline and weekly during study intervention.
Blood samples are collected at baseline and at weeks 3 and 6 for cytokine analysis.
Ages Eligible for Study: | 18 Years to 60 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
DISEASE CHARACTERISTICS:
Newly diagnosed acute or relapsed myeloid or lymphoblastic leukemia
PATIENT CHARACTERISTICS:
No condition that would compromise the patient's ability to participate in the exercise rehabilitation program, including any of the following:
PRIOR CONCURRENT THERAPY:
United States, North Carolina | |||||
Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill | Recruiting | ||||
Chapel Hill, North Carolina, United States, 27599-7295 | |||||
Contact: Clinical Trials Office - Lineberger Comprehensive Cancer Cente 877-668-0683; 919-966-4432 |
UNC Lineberger Comprehensive Cancer Center |
National Cancer Institute (NCI) |
Principal Investigator: | Claudio L. Battaglini, PhD | UNC Lineberger Comprehensive Cancer Center |
Clinical trial summary from the National Cancer Institute's PDQ® database 
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Study ID Numbers: | CDR0000551972, UNC-LCCC-0526 |
First Received: | July 10, 2007 |
Last Updated: | July 29, 2008 |
ClinicalTrials.gov Identifier: | NCT00499759 |
Health Authority: | Unspecified |
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