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| Sponsored by: |
Sheba Medical Center |
| Information provided by: | Sheba Medical Center |
| ClinicalTrials.gov Identifier: | NCT00498576 |
Purpose
Recently we have shown that melatonin secretion is impaired in rats with metabolic syndrome. We have also demonstrated that exogenic melatonin supplementation can improve blood pressure profile in nondipper patients.
The aim of this study is to find whether there is a difference between melatonin secretion in hypertensive kidney recipients versus "normal" hypertensive patients. Secondly, to ask if there is any correlation between melatonin secretion and adiponectin levels.
| Condition |
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Hypertension Kidney Transplant |
| MedlinePlus related topics: | High Blood Pressure Kidney Transplantation |
| ChemIDplus related topics: | Melatonin |
| Study Type: | Observational |
| Study Design: | Case Control, Prospective |
| Estimated Enrollment: | 60 |
| Study Start Date: | September 2007 |
| Groups/Cohorts |
|
1
kidney transplant with hypertension
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2
hypertensive patients with native kidneys
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3
healthy controls
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Eligibility
| Ages Eligible for Study: | 18 Years to 70 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
| Sampling Method: | Non-Probability Sample |
group1- patients from the kidney transplant unit, sheba medical center group2- patients from hypertension unit,sheba medical center
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations| Contact: Avshalom Leibowitz, MD | 972-3-530-2834 | leiboa@gmail.com |
| Israel | |||||
| Sheba Medical Center | Recruiting | ||||
| Ramat-gan, Israel | |||||
| Principal Investigator: Avshalom Leibowitz, MD | |||||
| Sheba Medical Center |
| Principal Investigator: | Avshalom Leibowitz, MD | Unaffiliated. |
More Information
| Responsible Party: | Sheba Medical Center ( leibowitz avshalom ) |
| Study ID Numbers: | SHEBA-07-4730-AL-CTIL |
| First Received: | July 8, 2007 |
| Last Updated: | May 5, 2008 |
| ClinicalTrials.gov Identifier: | NCT00498576 |
| Health Authority: | Israel: Israeli Health Ministry Pharmaceutical Administration |
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