A Study on a New Staining Method (C4d Staining) of Transplanted Kidney Biopsies - Full Text View

A Study on a New Staining Method (C4d Staining) of Transplanted Kidney Biopsies

This study has been completed.

Sponsored by:	Hospital Authority, Hong Kong
Information provided by:	Hospital Authority, Hong Kong
ClinicalTrials.gov Identifier:	NCT00498095

Purpose

Patients who had received kidney transplantation may suffer from rejection. Recently, positive staining for C4d in kidney biopsies of malfunctioning transplant kidney is increasingly recognized as an important prognostic indicator of poorer long-term kidney outcome. Data is, however, lacking in Hong Kong.

Condition	Intervention
Kidney Transplantation Graft Rejection	Procedure: Renal biopsy

MedlinePlus related topics:

Kidney Transplantation

U.S. FDA Resources

Study Type:	Observational
Study Design:	Prospective

Official Title:	Experience of C4d Staining in Renal Allograft Biopsies

Further study details as provided by Hospital Authority, Hong Kong:

Enrollment:	40
Study Start Date:	July 2006
Study Completion Date:	December 2006

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both

Criteria

Inclusion Criteria:

All renal allograft biopsies performed in Princess Margaret Hospital (PMH) during the period 1st April 2003 to 31st August 2005 for unexplained acute renal dysfunction (Creatinine rise from baseline by ≥ 20%) or delayed graft function in the immediate post-transplantation period were included in the study. Both cadaveric and living-donor transplant allografts were included.

Exclusion Criteria:

patients who were < 18 years' old at the time of renal biopsy or whose records were so incomplete that preclude meaningful analysis

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00498095

Locations


China
	Princess Margaret Hospital
	Hong Kong, China

Sponsors and Collaborators

Hospital Authority, Hong Kong

Investigators


Principal Investigator:	Sze Kit Yuen, Dr	Department of Medicine & Geriatrics, ICU, Caritas Medical Centre

More Information

HAREC Clinical Trial Registry This link exits the ClinicalTrials.gov site

Study ID Numbers:	KW/EX/06-054, HARECCTR0500061
First Received:	July 6, 2007
Last Updated:	June 17, 2008
ClinicalTrials.gov Identifier:	NCT00498095
Health Authority:	Hong Kong: Ethics Committee

Keywords provided by Hospital Authority, Hong Kong:

Delayed renal graft function

Acute renal allograft dysfunction

ClinicalTrials.gov processed this record on October 06, 2008