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Sponsored by: |
Oklahoma State University Center for Health Sciences |
Information provided by: | Oklahoma State University Center for Health Sciences |
ClinicalTrials.gov Identifier: | NCT00324402 |
To evaluate the maternal blood concentrations of brain natriuretic peptide (BNP) during the second and third trimesters of a normal pregnancy. We will attempt to define a normal range for pregnancy and any outliers that may serve as markers for abnormal cardiovascular physiology.
Condition |
Cardiomyopathy Pregnancy |
MedlinePlus related topics: | Cardiomyopathy |
ChemIDplus related topics: | Nesiritide |
Study Type: | Observational |
Study Design: | Cohort, Prospective |
Official Title: | Plasma Brain Natriuretic Peptide Levels in Pregnancy |
Estimated Enrollment: | 50 |
Study Start Date: | August 2006 |
Study Completion Date: | June 2008 |
Groups/Cohorts |
1
Healthy pregnant women, 18-40
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The brain natriuretic peptide (BNP) is a useful marker for volume overload, increased filling pressures and stretching of the myocardium. The current literature contains limited and unreliable information regarding normal BNP values in pregnancy. After baseline echocardiogram to detect individuals with asymptomatic structural defects, the participants will submit to 3 blood draws during the second and third trimester and at delivery to determine normal pregnancy values.
Ages Eligible for Study: | 18 Years to 40 Years |
Genders Eligible for Study: | Female |
Accepts Healthy Volunteers: | Yes |
Sampling Method: | Non-Probability Sample |
Healthy pregnant women, 18-40
Inclusion Criteria:
Exclusion Criteria:
United States, Oklahoma | |||||
Oklahoma State University Center for Health Sciences | |||||
Tulsa, Oklahoma, United States, 74127 |
Oklahoma State University Center for Health Sciences |
Study Chair: | Kimberly A Sorensen, DO | Oklahoma State University Center for Health Sciences |
Principal Investigator: | John M Beal, DO | Oklahoma State University Center for Health Sciences |
Responsible Party: | Oklahoma State University Center for Health Sciences ( Dr. J. Martin Beal, assistant professor of Ob/Gyn ) |
Study ID Numbers: | 2005008 |
First Received: | May 9, 2006 |
Last Updated: | July 8, 2008 |
ClinicalTrials.gov Identifier: | NCT00324402 |
Health Authority: | United States: Institutional Review Board |
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