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Sponsored by: |
Cordis Corporation |
Information provided by: | Cordis Corporation |
ClinicalTrials.gov Identifier: | NCT00403338 |
1500 eligible patients will be treated with the commercially available CYPHER® sirolimus-eluting Bx Velocity™ stent. Patients will be followed to twelve months post-procedure, watching for patients that require a repeat procedure on the same diseased area of the coronary artery.
Condition | Intervention | Phase |
Coronary Stenosis |
Device: CYPHER® Bx Velocity™ stent (sirolimus-eluting) |
Phase IV |
ChemIDplus related topics: | Sirolimus |
Study Type: | Observational |
Study Design: | Prospective |
Official Title: | Prospective Evaluation of the Impact of Stent Deployment Techniques on Clinical Outcomes of Patient Treated With the CYPHER® Stent, The e-CYPHER(SM)S.T.L.L.R., Registry [Study of Deployment Technique on Clinical Results] |
Enrollment: | 1500 |
Study Start Date: | December 2004 |
Study Completion Date: | April 2006 |
Geographical miss has been associated with treatment failures after intracoronary radiation therapy. This phenomenon, which is secondary to vascular injury outside the treated segment, was strongly correlated with the development of restenosis at the edges of the treated coronary segment. The European and Canadian SIRIUS trials (E and C-SIRIUS) randomized 350 patients with similar baseline characteristics of the US SIRIUS study. Operators used shorter post-dilatation balloons and direct stented 27% of the patients, achieving a 4.0% TLR rate and a 5.1% in-lesion binary restenosis. These somewhat superior results support the concept that refinement in deployment techniques may further improve clinical outcomes of drug-eluting stents.
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion criteria:
Exclusion criteria:
Study ID Numbers: | P03-6323 |
First Received: | November 22, 2006 |
Last Updated: | July 8, 2008 |
ClinicalTrials.gov Identifier: | NCT00403338 |
Health Authority: | United States: Institutional Review Board |
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