|
|
|
|
|
|
Sponsors and Collaborators: |
Imperial College London The Hypertension Trust |
Information provided by: | Imperial College London |
ClinicalTrials.gov Identifier: | NCT00131807 |
The purpose of this study is to explore the association between blood pressure, HIV and/or its treatment in a cross sectional observational study.
Condition | Intervention |
HIV Infections |
Procedure: Blood Pressure Measurement Procedure: Questionnaire |
MedlinePlus related topics: | AIDS |
Study Type: | Observational |
Study Design: | Natural History, Cross-Sectional, Random Sample, Prospective Study |
Official Title: | A Study to Explore the Association Between Blood Pressure, HIV and Antiretroviral Therapy |
Estimated Enrollment: | 3000 |
Study Start Date: | September 2005 |
Study Completion Date: | September 2006 |
Deaths from AIDS have declined dramatically since the introduction of highly active antiretroviral therapy in HIV infected patients. However the incidence of heart disease has increased four-fold and is now one of the major causes of death in HIV infected patients. While HIV drugs are known to adversely affect serum lipids, the evidence concerning the association between raised blood pressure (a major risk for cardiovascular disease) HIV and/or its treatment is limited and conflicting. The researchers believe it of interest to study heart disease risk factors in patients with HIV infection to avoid one premature cause of death (AIDS) being replaced with another potentially preventable cause of death and disability (heart disease). In this cross sectional observational study the researchers will systematically measure blood pressure and other cardiovascular risk factors in HIV positive patients on and off antiretroviral therapy. These individuals will be matched for age, sex and ethnic group with HIV negative individuals.
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
Exclusion Criteria:
United Kingdom, London | |||||
St. Mary's Hospital | |||||
Paddington, London, United Kingdom, W2 1NY |
Imperial College London |
The Hypertension Trust |
Principal Investigator: | Neil R Poulter | Imperial College London |
Study ID Numbers: | NPSW03 |
First Received: | August 18, 2005 |
Last Updated: | April 25, 2007 |
ClinicalTrials.gov Identifier: | NCT00131807 |
Health Authority: | United Kingdom: Research Ethics Committee |
|
|
|
|