|
|
|
|
|
|
Sponsored by: |
University of Ulm |
Information provided by: | University of Ulm |
ClinicalTrials.gov Identifier: | NCT00223548 |
The purpose of this study is to determine wether Mesna could prevent contrast-induced nephropathy
Condition | Intervention | Phase |
Chronic Renal Insufficiency Serum Creatinine Concentration Contrast Media Exposition |
Drug: sodium 2-mercaptoethane sulfonate |
Phase II |
ChemIDplus related topics: | Mesna |
Study Type: | Interventional |
Study Design: | Prevention, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Efficacy Study |
Official Title: | MESNA Zur Prophylaxe Der Kontrastmittel-Induzierten Nephropathie |
Estimated Enrollment: | 106 |
Study Start Date: | October 2002 |
Estimated Study Completion Date: | December 2004 |
Contrast-induced nephropathy remains a common complication of radiographic precedures. Pretreatment with Mesna (Sodium 2-mercaptoethane sulfonate) in combination with sodium chloride is more protective than sodium chloride alone in animal models of acute renal failure.
The aim of this study is therefore to determine laboratory and clinical benefit of MESNA, as an adjunct to saline hydration, in patients with known renal impairment receiving contrast media.
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Germany | |||||
Division of Nephrology, University of Ulm | |||||
Ulm, Germany, 89081 |
University of Ulm |
Principal Investigator: | Frieder Keller, M.D. | Division of Nephrology, University Hospital Ulm |
Principal Investigator: | Frieder Keller, M.D. | Division of Nephrology, University Hospital of Ulm |
Study ID Numbers: | A119/2002 |
First Received: | September 14, 2005 |
Last Updated: | September 14, 2005 |
ClinicalTrials.gov Identifier: | NCT00223548 |
Health Authority: | Germany: Federal Institute for Drugs and Medical Devices |
|
|
|
|