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Intravitreal Bevacizumab for the Treatment of Central Serous Chorioretinopathy

This study is currently recruiting participants.
Verified by Asociación para Evitar la Ceguera en México, June 2006

Sponsored by: Asociación para Evitar la Ceguera en México
Information provided by: Asociación para Evitar la Ceguera en México
ClinicalTrials.gov Identifier: NCT00418431
  Purpose

Central serous chorioretinopathy (CSC) has been known since it was first described by Von Graefe and termed “idiopathic detachment of the macula” in 1866, is a well-characterized disorder leading to serous neurosensory elevation of the central macula. The acute form of the disease is associated with focal leakage at the level of the retinal pigment epithelium (RPE) demonstrated with fluorescein angiography (FA). The disorder is self-limited in the majority of patients, who also regain excellent vision. Occasionally, the neurosensory detachment persists and leads to pigment epithelial and photoreceptor damage with visual impairment.

The purpose of this clinical study is report the use of intravitreal bevacizumab is a new option in the treatment of the chronic or recurrent CSC.


Condition Intervention Phase
Central Serous Chorioretinopathy
Drug: Intravitreal injection of Bevacizumab
Phase II
Phase III

ChemIDplus related topics:   Bevacizumab   

U.S. FDA Resources

Study Type:   Interventional
Study Design:   Treatment, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment

Further study details as provided by Asociación para Evitar la Ceguera en México:

Study Start Date:   April 2006
Estimated Study Completion Date:   August 2006

  Eligibility
Ages Eligible for Study:   20 Years to 50 Years
Genders Eligible for Study:   Both

Criteria

Inclusion Criteria

  • Any visual acuity.
  • Central serous chorioretinopathy
  Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00418431

Contacts
Contact: Mitzy E Torres Soriano, MD     525510841400 ext 1172     retinamex@yahoo.com    
Contact: Hugo Quiroz-Mercado, MD     525510841400 ext 1171     hugoquiroz@yahoo.com    

Locations
Mexico, DF
Asociacion para Evitar la Ceguera en Mexico     Recruiting
      Mexico DF, DF, Mexico, 04030
      Contact: Mitzy E Torres Soriano, MD     5255510841400 ext 1171     mitzytorres@yahoo.com    
      Sub-Investigator: Maura Abraham, MD            
      Sub-Investigator: Orlando Ustariz, MD            
      Sub-Investigator: Gerardo Garcia Aguirre            
      Sub-Investigator: Veronica Kon-Jara, MD            
      Sub-Investigator: Hugo Quiroz-Mercado, MD            
      Sub-Investigator: Jose L Guerrero, MD            

Sponsors and Collaborators
Asociación para Evitar la Ceguera en México

Investigators
Principal Investigator:     Mitzy E Torres Soriano, MD     APEC    
  More Information


Study ID Numbers:   APEC-0016
First Received:   January 3, 2007
Last Updated:   January 3, 2007
ClinicalTrials.gov Identifier:   NCT00418431
Health Authority:   MEXICO : SECRETARIA DE SALUD

Study placed in the following topic categories:
Bevacizumab
Central serous chorioretinopathy

Additional relevant MeSH terms:
Antineoplastic Agents
Therapeutic Uses
Growth Substances
Physiological Effects of Drugs
Growth Inhibitors
Angiogenesis Modulating Agents
Angiogenesis Inhibitors
Pharmacologic Actions

ClinicalTrials.gov processed this record on September 23, 2008




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