Study Evaluating AGG-523 in Subjects With Osteoarthritis - Full Text View

Study Evaluating AGG-523 in Subjects With Osteoarthritis

This study has been completed.

Sponsored by:	Wyeth
Information provided by:	Wyeth
ClinicalTrials.gov Identifier:	NCT00427687

Purpose

This study will evaluate the effect of AGG-523 administration on biomarkers related to osteoarthritis. Safety and tolerability of AGG-523 will also be assessed.

Condition	Intervention	Phase
Osteoarthritis	Drug: AGG-523	Phase I

MedlinePlus related topics:

Osteoarthritis

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment

Official Title:	A Randomized, Double-Blind, Placebo-Controlled, Multiple-Dose, Parallel-Group Study of the Pharmacodynamics, Safety, Tolerability, and Pharmacokinetics of AGG-523 Administered Orally to Subjects With Mild to Moderate Osteoarthritis

Further study details as provided by Wyeth:

Primary Outcome Measures:

The effect of AGG-523 on biomarkers related to osteoarthritis.

Study Start Date:	February 2007
Study Completion Date:	June 2007

Eligibility

Ages Eligible for Study:	40 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion:

Mild to moderate Osteoarthritis of the target knee.
Subjects must be generally healthy but enrolled with stable chronic illness if well controlled.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00427687

Locations


United States, California

	Anaheim, California, United States, 92801

United States, Florida

	Miami, Florida, United States, 33143

United States, Pennsylvania

	Altoona, Pennsylvania, United States, 16635

Sponsors and Collaborators

Wyeth

Investigators


Study Director:	Medical Monitor	Wyeth

More Information

Study ID Numbers:	3189A1-104
First Received:	January 25, 2007
Last Updated:	August 1, 2008
ClinicalTrials.gov Identifier:	NCT00427687
Health Authority:	United States: Food and Drug Administration

Study placed in the following topic categories:

Musculoskeletal Diseases

Osteoarthritis

Joint Diseases

Arthritis

Rheumatic Diseases

ClinicalTrials.gov processed this record on September 23, 2008